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保乳手术和改良根治术治疗早期乳腺癌的临床疗效分析 预览 被引量:15

Clinical analysis of breast-conserving surgery and modified radical mastectomy for early breast cancer
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摘要 目的探讨和比较保乳手术和改良根治术治疗早期乳腺癌的临床疗效和安全性。方法回顾性分析2013年1月至2015年9月期间接受外科手术治疗的100例早期乳腺癌手术患者的临床资料,根据患者的手术方式进行分组,其中保乳手术组(保乳组)50例,改良根治术组(改良组)50例,采用SPSS19.0统计分析,两组患者的手术时间、术中出血量、住院天数等用“均数±标准差”表示,组问比较采用t检验;术后并发症发生情况、乳房美容效果、术后肿瘤局部复发率、远处转移率、1年生存率等用“%”形式表示,组间比较采用Y。检验。P〈0.05差异有统计学意义。结果保乳组手术时间、术中出血量、住院时间及术后并发症发生率均少于改良组(P〈0.05),美容效果优良率高于改良组(P〈0.05)。两组患者术后肿瘤局部复发率、远处转移率、1年生存率差异均无统计学意义(P〉0.05)。结论保乳手术与改良根治术治疗早期乳腺癌疗效确切,但保乳手术对患者损伤小、出血量少、并发症少、美容效果好,值得推广应用。 Objective To investigate and compare the clinical outcome of breast-conserving surgery" and modified radical mastectomy for patients with early breast cancer. Methods Clinical data of 100 patients with early breast cancer from January 2013 to September 2015 were retrospectively analyzed. 100 of patients were divided into breast conserving operation group (50 cases) and modified radical operation group (50 cases). Statistical analysis were performed by using SPSS 19.0 software. Perioperative measurement data such as operation time, intraoperative blood loss and postoperative hospital stay were expressed as mean ± standard deviation ( ±s) , and were examined by using t test. The postoperative complications, breast cosmetic effects, local recurrence rates, distant metastasis rates and 1-year survival rates were expressed as "% " and analyzed by Chi-square test. A P value 〈 0. 05 was considered as statistically significant difference. Results The operation time, intraoperative blood loss, postoperative hospital stay and postoperative complications in breast-conserving group were much less than those in modified radical group, with significant difference (P 〈 0.05). The breast cosmetic effects in breast-conserving group was better than that in modified radical group, with significant difference (P 〈 0. 05 ). There was no significant difference of the local recurrence rates, distant metastasis rates and 1-year survival rates between two groups ( P 〉 0.05 ). Conclusion Both breast conserving operation and modified radical operation could achieve curative effect for patients with early breast cancer, however breast conserving surgery has the advantages of less injury, less blood loss, less clinical complications and better cosmetic resuhs, which is worth clinical promotion.
作者 李翔 Li Xiang(Department of Thyroid and Breast Surgery, the Fourth People's Hospital of Zigong City, Zigong 643000, China)
出处 《中华普外科手术学杂志(电子版)》 2017年第3期222-225,共4页 Chinese Journal of Operative Procedures of General Surgery(Electronic Version)
关键词 乳腺肿瘤 乳房切除术 改良根治性 保乳手术 Breast neoplasms Mastectomy, modified radical Breast conserving operation
作者简介 通信作者:李翔,Email:Li_xiang0918@126.com
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