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督灸联合塞来昔布胶囊治疗强直性脊柱炎肾阳亏虚证的疗效观察 预览 被引量:6

Observation of the Therapeutic Effect of Du-moxibustion Combined with Celecoxib Capsules in the Treatment ofAnkylosing Spondylitis with Kidney Yang Deficiency
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摘要 目的:观察应用督灸联合塞来昔布胶囊治疗强直性脊柱炎肾阳亏虚证的临床疗效。方法:选取强直性脊柱炎肾阳亏虚证患者60例,随机分为督灸组、西药组及联合组,每组20例。督灸组给予隔姜督灸治疗;西药组给予塞来昔布胶囊口服;联合组给予隔姜督灸联合塞来昔布胶囊口服治疗;3组均治疗3个月。治疗后应用国际强直性脊柱炎评估工作组(ASAS)制定的疗效评价因子及中医证候评分进行临床疗效对比,同时进行安全性评价。结果:3组患者治疗后ASAS疗效评价因子及中医证候评分较治疗前均有显著改善(P〈0.05),治疗后3组患者PGA评分、脊柱活动度、枕墙距、晨僵时间、红细胞沉降率、中医证候积分、中医证候疗效的比较,联合组优于其他2组,差异有统计学意义(P〈0.05);3组患者均未出现严重的不良反应。结论:督灸联合塞来昔布胶囊治疗强直性脊柱炎肾阳亏虚证疗效显著,安全有效,具有较高的临床价值。 Objective:To observe the clinical efficacy of du-moxibustion ( moxibustion on du mai ) combined with Celecoxib Capsules in the treatment of ankylosing spondylitis with kidney yang deficiency. Methods:Sixty cases of ankylosing spondylitis with kidney yang deficiency syndrome were randomly divided into a du-moxibustion group,a western medicine group and a combined group,20 cases in each group.The dumoxibustion group was treated with moxibustion on ginger, and the western medicine group was treated with Celecoxib Capsules.The combined group was treated with above two methods.The three groups were treated for 3 months.After treatment,therapeutic evaluation factors made by ASAS and TCM syndrome scores were used to compare the efficacies,and safety evaluation was carried out at the same time.Results:After treatment,the therapeutic evaluation factors and TCM syndrome scores of the three groups were significantly improved than those before treatment ( P 〈 0.05 ) .The PGA score,spinal mobility, pillow wall distance,morning stiffness time,erythrocyte sedimentation rate,TCM syndrome score,TCM syndrome of the combined group were better than those of the other two groups,and the difference was statistically significant ( P 〈 0.05 ) .There were no serious adverse reactions in the three groups.Conelusion:Du-moxibustion combined with Celecoxib Capsules in the treatment of ankylosing spondylitis with kidney yang deficiency syndrome is effective and safe,and has a high clinical value.
作者 刘怀省 乔登朝 韩文朝 王少华 LIU Huai-sheng, QIAO Deng-chao, HAN Wen-chao, WANG Shao-hua
出处 《风湿病与关节炎》 2017年第7期29-33,共5页 RHEUNATISM AND ARTHRITIS
关键词 脊柱炎 强直性 督灸 肾阳亏虚证 塞来昔布 spondylitis,ankylosing Du-moxibustion kidney yang deficiency syndrome celecoxib
作者简介 通信作者:乔登朝E-mail:2577445273@qq.com
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