Objective To investigate the curative effect of modified Bushen Zhidai decoction and Zhibai Dihuang pills in the treatment of senile vaginitis of liver and kidney yin deficiency. Methods 58 cases of senile vaginitis of liver and kidney yin deficiency from June 2016 to December 2016 were selected,and they were randomly divided into groups,with 29 cases in each group. The control group was treated with metronidazole. The observation group was treated with modified Bushen Zhidai decoction and Zhibai Dihuang pills. The clinical effect,the pH value of the vagina and serum sex hormone [estradiol（ E2） and follicle stimulating hormone（ FSH） ]levels was compared between the two groups. Results The total effective rate of the observation group was 93. 10%（ 27/29） which was higher than 68. 97%（ 20/29） of the control group,and the difference was statistically significant（ P 0. 05）. After treatment,the vaginal pH value and serum E2 level of the observation group were lower those of the control group,the level of FSH of the observation group was higher than that of the control group,and the difference was statistically significant（ P 0. 05）. Conclusion Modified Bushen Zhidai decoction and Zhibai Dihuang pills is effective in the treatment of senile vaginitis of liver and kidney yin deficiency,which can effectively improve vaginal pH value and serum sex hormone level.
Journal of Traditional Chinese Medicine
Modified Bushen Zhidai decoction
Zhibai Dihuang pills
Senile vaginitis of liver kidney yin deficiency type
Therapy of TCM