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补阳还五汤对周围性面瘫合并无症状性脑梗死患者的临床疗效及预后影响 预览 被引量:6

Clinical and Prognostic Effects of Buyang Huanwu Decoction in the Treatment of Patients with Peripheral Facial Paralysis Combined with Asymptomatic Cerebral Infarction
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摘要 目的:分析补阳还五汤对周围性面瘫(PFP)合并无症状性脑梗死(ACI)患者的临床疗效及预后影响。方法:选取2012年8月至2015年8月首都医科大学附属复兴医院收治的PFP合并ACI患者60例,按数字随机表法分为观察组与对照组,每组30例。对照组单纯应用西医疗法,观察组另给予补阳还五汤,治疗2个月后比较2组疗效,治疗后复查CT的结果,以及治疗前后的面神经功能评分(MHBN)。结果:观察组的治愈率以及总有效率分别是33.33%、96.67%,较对照组的10.00%、73.22%明显更高,差异均有统计学意义(均P〈0.05)。观察组治疗后复查CT显示病灶密度下降以及病灶面积减少〉1/2的比例分别是96.67%、70.00%,较对照组的70.00%、46.67%明显更高,差异均有统计学意义(均P〈0.05)。2组治疗后的MHBN评分较治疗前均有明显改善,且治疗后观察组的MHBN评分显著高于对照组,差异均有统计学意义(均P〈0.05)。结论:利用补阳还五汤对PFP合并ACI患者实施治疗的疗效明显,有助于临床症状的改善,值得给予推荐。 Objective: To study the clinical and prognostic effects of Buyang Huanwu Decoction in the treatment of peripheral facial paralysis( PFP) patients with peripheral facial paralysis combined with asymptomatic cerebral infarction( ACI). Methods: A total of 60 cases of patients of PFP with ACI who were admitted and treated in Fuxing Hospital Affiliated to Capital University of Medical Sciences from August 2012 to August 2015 were randomly divided into the observation group and the control group,with 30 cases in each group. Patients in the control group were treated with western medicine therapy,and patients in the treatment group were given Buyang Huanwu Decoction. The curative effects were compared between the two groups after 2 months treatment,and the results of CT were reviewed. The facial nerve function score( MHBN) was observed before and after treatment. Results: The cure rate and total effective rate of observation group were 33. 33% and 96. 67%,respectively,compared with the control group of 10. 00%,73. 22%,which were significantly higher and the difference was statistically significant( P〈0. 05). After treatment,CT showed that the rates of density of the lesions and the area of the lesions decreased more than 1/2 were 96. 67% and 70. 00%,respectively,compared with the control group of 70. 00%,46. 67%,which were significantly higher and the difference was statistically significant( P〈0. 05). The MHBN score after treatment in two groups were significantly improved compared with before treatment,and the MHBN score in the observation group was significantly higher than that in the control group. The difference was statistically significant( P〈0. 05). Conclusion: The effects of Buyang Huanwu Decoction in the treatment of patients with PFP combined with ACI were significant,which can help to improve the clinical symptoms and was worthy to be recommended.
作者 李春林 杨慧 Li Chunlin, Yang Hui ( Department of TCM, Fuxing Hospital Affiliated to Capital Medical University, Beijing 100038, China )
出处 《世界中医药》 CAS 2018年第2期386-388,392共4页
基金 北京市科技计划项目(Z111107056811040)
关键词 补阳还五汤 周围性面瘫 无症状性脑梗死 疗效 预后 Buyang Huanwu Decoction Peripheral facial paralysis Asymptomatic cerebral infarction Curative effect Prognosis
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