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External application of Chinese medicine formula combined with analgesic drugs to treat lung squamous cell carcinoma pain: A case study with mixed methods 预览

External application of Chinese medicine formula combined with analgesic drugs to treat lung squamous cell carcinoma pain: A case study with mixed methods
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摘要 目的:探讨外用中药联合镇痛药治疗肺鳞状细胞癌的疗效.方法:研究了一名54岁的左肺鳞癌患者,当患者入院时患有严重的癌症疼痛,最初的数字评价量表(NRS)为7分.将外用配方应用于疼痛部位以减轻疼痛.采用包括NRS,简化McGill疼痛问卷调查表,生活质量量表,突发疼痛次数,不良反应记录和半结构式访谈的混合方法评估疗效.结果:结合使用配方和镇痛药物,患者的NRS评分从7分下降到3分.生活质量评分从33分提高到42分.爆发性疼痛的次数从两次减少到一次.羟考酮的用量从30mgBid降至10mgBid.没有不利影响出现.病人的睡眠和食欲更加充沛.结论:与镇痛药联用时,该配方止痛有效安全,可能是治疗局部癌症疼痛的良好选择.需要进一步行随机对照研究来更好地评估疗效. Objective: To investigate the effectiveness of the external application of Chinese medicine combined with analgesicdrugs to treat lung squamous cell carcinoma pain. Methods: A 54-year-old patient with upper lobe of the left lungsquamous cell carcinoma was studied, who suffered from severe cancer pain with the initial numeric rating scale (NRS)7 point when admitted. Exterior-use formula was applied to pain spot to relieve the pain. Mixed methods approachcomprising NRS, Short-form of McGill Pain Questionnaire, quality of life scale, times of breakout pain, records ofadverse reactions and semi-structured interviews were utilized to evaluate the effect. Results: With the combination useof the formula and analgesic drugs, the patient’s NRS score dropped from 7 to 3 point. Quality of life scale scoreimproved from 33 to 42 point. Times of breakout pain reduced from twice to none. The amount of oxycodone decreasedfrom 30 mg Bid to 10 mg Bid. No adverse effect appeared. The patient’s felt more energetic with good sleep and appetite.Conclusion: This formula is effective and safe for pain relief when combined with analgesic drugs, and may be a goodoption in dealing with local cancer pain. Future randomized, controlled studies are needed to better evaluate the efficacy.
出处 《TMR现代中药》 2018年第1期29-34,共6页 TMR Modern Herbal Medicine
关键词 癌症疼痛 中医药 病例研究 混合方法 Cancer pain, Chinese medicine, Case study, Mixed methods
作者简介 Correspondence to: Yu-Fang Hao, Nursing School, Beijing University of Chinese Medicine, Beijing, China. E-mail:haoyufangbucm@163.com.
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