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血清胆碱酯酶测定在脓毒症患者中的应用价值 预览

Value of Serum Cholinesterase Determination in Patients With Sepsis
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摘要 目的探讨血清胆碱酯酶水平与脓毒症患者病情严重程度及预后的关系。方法分析脓毒症患者50例,按照入院24小时内APACHEⅡ评分不同分为2组,其中≤20分为A组,≥21分为B组,测定入院24小时内血清胆碱酯酶水平,分析其与APACHEⅡ评分的关系。结果全组患者血清胆碱酯酶水平与APACHEⅡ评分呈负相关(r=-0.444,P〈0.05);B组血清胆碱酯酶水平低于A组(P〈0.05),死亡组血清胆碱酯酶水平低于存活组(P〈0.05)。结论血清胆碱酯酶测定对于早期评估脓毒症患者病情严重程度和预后具有一定价值。 Objective To exlpore the relationship between serum levels of cholinesterase and severity and prognosis of sepsis. Methods 50 patients defined as sepsis were assigned into 2 groups according to the APACHE-II score within 24 hours of admission. The patients whose APACHE-II score ≤ 20 were assigned into Group A. The patients whose APACHE-II score 〉20 were assigned into Group B. The contents of serum cholinesterase in group A and group B were determined within 24 h of hospital to analyze its relationship with APACHE-II score. Results The serum cholinesterase level was negatively correlated with APACHEII score(r =-0.444, P =0.05). The serum cholinesterase level in group B was significantly lower than that in group A(P〈0.05), and the serum cholinesterase level in death group was significantly lower than that in survival group(P〈0.05). Conclusion The determination of serum cholinesterase is valuable for early assessment of the severity and prognosis of sepsis.
作者 耿英杰 GENG Yingjie( Department of Critical Care Medicine, Beijing Shijingshan Hospital, Beijing 100043, China)
出处 《中国卫生标准管理》 2018年第11期57-59,共3页
关键词 脓毒症 胆碱酯酶 APACHE Ⅱ评分 严重程度 预后 早期 sepsis cholinesterase APACHE-II score severity prognosis early stage
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  • 1徐远达,黎毅敏,萧正伦,刘晓青,何为群,钟南山.连续性血液净化对重症肺炎合并多器官功能衰竭的回顾性分析[J].中国危重病急救医学,2005,17(12):747-751. 被引量:16
  • 2社区获得性肺炎诊断和治疗指南[J].中华结核和呼吸杂志,2006,29(10):651-655. 被引量:2556
  • 3陈文彬.诊断学[M].7版.北京:人民卫生出版社,2008:35-37. 被引量:182
  • 4王超,苏强,张淑文,阴赪宏,王红,王宝恩.多器官功能障碍综合征病情严重度评分系统[J].中国医学科学院学报,2007,29(4):497-500. 被引量:26
  • 5钱德才,黄明康,田云,张进,黄其建,王强.急性有机磷农药中毒时血清胆碱酯酶的测定时机及其意义[J].中国危重病急救医学,2007,19(12):738-738. 被引量:3
  • 6Mandell LA, Wunderink RG, Anzueto A, et al. Infectious Diseases Society of America/American Thoracic Society consensus guidelines on the management of community-acquired pneumonia in adults [J]. Clin Infect Dis, 2007, 44 Suppl 2 : $27-72. DOI: 10.1086/511159. 被引量:1
  • 7Richards G, Levy H, Laterre PF, et al. CURB-65, PSI, and APACHE I] to assess mortality risk in patients with severe sepsis and community acquired pneumonia in PROWESS [J]. J Intensive Care Med, 2011, 26 (1): 34-40. 被引量:1
  • 8Restrepo MI, Mortensen EM, Velez JA, et al. A comparative study of community-acquired pneumonia patients admitted to the ward and the ICU [J]. Chest, 2005, 133 (3): 610-617. DOI: 10.1378/chest.07-1456. 被引量:1
  • 9American Thoracic Society, Infectious Diseases Society of America. Guidelines for the management of adults with hospital-acquired, ventilator-associated, and healthcare-associated pneumonia [J]. Am J Respir Crit Care Med, 2005, 171 (4): 388-416. DOI: 10.1164/. 被引量:1
  • 10Hsieh BC, Hsiao HY, Cheng TJ, et al. Assays for serum cholinesterase activity by capillary electrophoresis and an amperometric flow injection choline biosensor [J]. Anal Chim Acta, 2008, 623 (2): 157-162. DOI: 10.1016/j.aca.2008.06.008. 被引量:1

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