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先天畸形的发生情况、诊断及妊娠结局分析

The occurrence of congenital malformation,diagnosis and analysis of pregnancy outcome
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摘要 目的探究先天畸形的发生情况、诊断及妊娠结局,明确产科临床工作特点及重点。方法描述性方法,将2014年6月-2017年6月在我院常规产检及分娩的21 500例孕产妇作为研究对象,对胎儿畸形发生情况予以总结,明确胎儿畸形类型,并随访孕产妇的妊娠结局,观察其分娩方式及引产率。结果 2014年6月-2017年6月先天畸形胎儿共为35例,先天畸形发生率为0.163%,其中多发畸形、心脏畸形以及泌尿生殖系统畸形发生率最高。产前诊断出先天畸形为32例,占91.43%,主要通过超声诊断及染色体检查等检出,产后诊断出先天畸形为3例,占8.57%;对产妇妊娠结局予以随访,结果显示共有25例选择引产,引产率为65.71%,其中神经系统畸形引产率最高,占100.0%。结论孕产妇孕期保健及出生缺陷监测是产科临床工作重点,应加强先天畸形诊断与监测,提升妊娠结局。 Objective:To explore the occurrence,diagnosis and pregnancy outcome of congenital malformations,and to clarify the clinical features and emphases of obstetrics. Methods:Descriptive method,will be in June 2014 to June 2017 in our hospital regular prenatal and delivery of 21500 cases of maternal as the research object,we summarize what is happening to fetal abnormalities,clear fetal malformation type,and follow-up of maternal pregnancy outcomes,the childbirth way and induced labor rate was observed. Results:From June 2014 to June,2017,there were 35 congenital malformed fetuses,and the incidence of congenital malformation was 0.163%,with the highest incidence of malformation,cardiac malformation and malformation of the genitourinary system. Prenatal diagnosis of congenital malformation was 32 cases,accounting for 91.43%,mainly through ultrasonography and chromosomal examination,and postpartum diagnosis of congenital malformation was 3 cases,accounting for 8.57%. The results showed that there were 25 cases of induced abortion and 71.43% induced labor rate,among which the incidence rate of nervous system malformation was 100%. Conclusion:The monitoring of maternal health and birth defects is the focus of obstetrics clinic,and the diagnosis and monitoring of congenital malformation should be strengthened to improve the pregnancy outcome.
作者 张莉 张耀 ZHANG Li,ZHANG Yao( The Women and Children Health Care Hospital ofHaikou, Hainan Haikou 570203 )
出处 《中国优生与遗传杂志》 2018年第9期78-79,110共3页 Chinese Journal of Birth Health & Heredity
关键词 先天畸形 产前诊断 妊娠结局 引产 Congenital malformation Prenatal diagnosis Pregnancy outcome Induced labor
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