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渭南市临渭区学龄前期儿童轮状病毒感染性腹泻流行特征调查研究 预览

Epidemiological Features of Rotavirus Infectious Diarrhea in Preschool Children in Linwei District of Weinan City
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摘要 目的 调查分析渭南市临渭区学龄前期儿童轮状病毒(RV)感染性腹泻疾病流行特征。方法 回顾性分析2015年1月-2017年12月渭南市临渭区605例学龄前期感染性腹泻儿童的临床资料,比较不同性别及不同年龄儿童RV感染情况,并分析RV感染发病时间、RV分型情况及RV感染儿童的临床特征。结果 605例患儿中91例(15.04%)患儿为RV感染阳性;不同性别患儿RV感染阳性率比较,差异无统计学意义(P〉0.05)。3岁儿童RV感染阳性率最高,占23.66%,明显高于4岁、5岁、6岁儿童(P〈0.05); 4岁儿童RV感染阳性率高于6岁儿童(P〈0.05);而5岁与6岁儿童RV感染阳性率比较,差异无统计学意义(P〉0.05)。RV感染发病时间以冬季为主,占比达57.14%; RV分型G血清型分型以G3血清型为主,占比70.33%; P基因型分型则以P8基因型为主,占比68.13%。RV感染儿童起病至就诊时间以1~3 d为主(70.33%);每日腹泻次数以5~6次为主(48.35%);大便性质主要为水样便(85.71%)及蛋花汤样便(75.82%);主要的合并症状有呕吐、呼吸道症状、发热,占比依次为61.54%、47.25%、34.07%。结论 渭南市临渭区学龄前期儿童RV感染性腹泻好发于低龄儿童,且冬季为高发季节,G3P8型为其RV优势流行性毒株,临床表现也有其特点,医疗服务机构可根据其流行病学特征进行防控。 Objective To explore the epidemiological features of rotavirus( RV) infectious diarrhea in preschool children in Linwei District of Weinan. Methods The clinical data of 605 preschool children with infectious diarrhea in Linwei District who were treated between January 2015 and December 2017 was retrospectively analyzed. The RV infections of children of different gender and age were compared. The onset time of RV infection,RV classification and clinical features of children with RV infection were analyzed. Results Among the 605 children,91 cases( 15.04%) were with positive RV infection. There was no significant difference in the positive rate of RV infection between children of different gender( P〈0.05). The positive rate of RV infection was the highest in three-year-old children( 23.66%),which was significantly higher than that of children aged four to six( P〈0.05). The positive rate of RV infection in 4-year-old children was also higher than that in 6-year-old children( P〈0.05).There was no significant difference in the positive rate of RV infection between 5-year-old children and 6-year-old ones( P〈0.05). The onset time of RV infection was mainly in winter,accounting for 57.14%. The G serotype of RV classification was mainly G3 serotype,accounting for 70.33%. The P genotype was mainly P8 genotype,accounting for 68.13%. The interval between onset and visits to doctors among the RV-infected children was 1 to 3 d( 70.33%). The frequency of daily diarrhea was 5-6 times( 48.35%). The stool was mainly watery( 85.71%) and seemed like egg-flower soup( 75.82%). The main combined symptoms were vomiting,respiratory symptoms and fever,accounting for 61.54%,47.25% and 34.07% respectively. Conclusion RV infectious diarrhea in preschool children in Linwei District of Weinan occurs in young children,and winter is a high-risk season.G3P8 is a dominant strain of RV,and its clinical manifestations also have its characteristics. Related institutions should enforce prevention and
作者 王亚利 田娟 郭斌 WANG Yali, TIAN Juan, GUO Bin (Department of Pediatrics, Weinan Central Hospital, Weinan Shaanxi 714000, China)
出处 《解放军预防医学杂志》 CAS 2018年第10期1235-1237,共3页 Journal of Preventive Medicine of Chinese People's Liberation Army
关键词 轮状病毒感染性腹泻 学龄前期 渭南市临渭区 流行特征 rotavirus infectious diarrhea Preschool Linwei District of Weinan City epidemiological features
作者简介 王亚利(1974-),女,大学本科,主治医师。从事儿科呼吸及消化系统疾病的诊断及治疗研究。
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