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中国儿童肺炎球菌疫苗接种情况调查分析

Vaccination coverage of pneumococcal vaccine among children in China: a cross-sectional study
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摘要 目的 了解中国儿童肺炎球菌疫苗(PV)的接种情况,为PV接种策略的制定提供参考依据。方法 从河北省、黑龙江省、上海市、江苏省、江西省、广东省、重庆市和甘肃省20个县(市、区)儿童预防接种信息管理系统中各随机抽取50名2008年1月1日—2012年12月31日出生的儿童,现场核对被调查儿童的预防接种证中PV接种信息进行统计分析。结果 共调查978名儿童,1、2、3、4剂次7价肺炎球菌结合疫苗(PCV7)的接种率分别为6.44%、3.37%、1.94%、1.23%,23价肺炎球菌多糖疫苗(PPV23)接种率为16.87%。2008、2009、2010、2011、2012年出生儿童1剂次PCV7接种率分别为8.12%、7.61%、4.62%、4.62%、7.22%,2008、2009、2010、2011年出生儿童PPV23接种率分别为23.86%、22.34%、18.97%、15.90%,不同出生年份儿童1剂次PCV7接种率和PPV23接种率差异均无统计学意义(P〉 0.05)。结论 中国儿童PCV7接种率较低,应通过公共卫生干预措施进一步提高儿童的PCV接种率,并进一步规范基层PPV23的接种服务,制定相应的疫苗接种指导意见。 Objective To examine the vaccination ofpneumococcal vaccine (PV) among children in China and to provide references for developing PV vaccination strategy. Methods We selected 20 counties (municipalities or districts) in 8 provincial regions as study sites and randomly recruited 50 children born in years between 2008 and 2012 in each of the counties from Children Vaccination Information Management System. Then we conducted on-site surveys on PV vaccination history among the children to evaluate vaccination rate of PV. Results Among the 978 children surveyed, the coverage rate for one, two, three, and four doses vaccination of 7-valent pneumococcal conjugate vaccine (PCV7) were 6.44%, 3.37%, 1.94%, and 1.23%, respectively, and the coverage rate of 23-valent pneumococcal conjugate vaccine (PCV23) was 16.87%. The coverage rate for one dose vaccination of PCV7 was 8.12%, 7.61%, 4.62%, 4.62%, and 7.22% for the children born in the year from 2008 to 2012 and the vaccination rate of PCV23 was 23.86%, 22.34%, 18.97%, and 15.90% for the children born in the year from 2008 to 2011, respectively. There was no significant difference in one dose PCV7 vaccination rate and in PCV23 vaccination rate among the children born in different years during the 5-year period (both P〉 0.05). Conclusion The vaccination rate of PCV7 is low among children in China, public health related intervention measures should be implemented to increase the coverage rate of pneumococcal conjugate vaccine among children, and PPV23 service should be further regulated.
作者 岳晨妍 韦宁 朱徐 王华庆 安志杰 YUE Chen-yan, WEI Ning, ZHU Xu, et al (National Immunization Program, Chinese Center for Disease Control and Prevention, Beijing 100050, China)
出处 《中国公共卫生》 CSCD 北大核心 2018年第11期1468-1470,共3页 Chinese Journal of Public Health
基金 联合国儿童基金会项目
关键词 肺炎球菌疫苗(PV) 接种率 儿童 pneumococcal vaccine vaccination rate children
作者简介 岳晨妍(1983-),女,山西文水人,助理研究员,硕士,主要从事免疫规划工作。;通信作者:安志杰,E-mail:anzj@chinacdc.cn
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