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Corvis ST分析中低度近视屈光手术后角膜生物力学的变化 预览

Analysis on biomechanical parameters about low to moderate myopia patients post refractive surgery by Corvis ST
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摘要 目的采用角膜生物力学分析测试系统即CorvisST研究中低度近视患者角膜屈光手术后角膜生物力学相关参数的变化,从角膜生物力学角度对屈光手术的安全性及有效性进行探讨。方法随机选择2015年3月~2016年10月就诊于内蒙古医科大学附属医院近视眼激光治疗中心的中低度近视患者100例(100眼),按手术方式不同分为前弹力层下激光角膜磨镶术(SBK)组及准分子激光原位角膜磨镶术(LASIK)组,每组患者50例(50眼)。对其进行相关术前检查及CorvisST检查,对手术前后及术后1个月两组患者的眼压(IOP)、中央角膜厚度(CCT)、第一压平时间(A-time1)及最大形变幅度(DA)等参数进行观察。结果两组屈光手术后IOP、CCT、A-time1值均较术前降低,差异均有统计学意义(P<0.05);手术前后DA值无明显变化,差异无统计学意义(P>0.05)。两组术前角膜生物力学参数比较,差异无统计学意义(P>0.05);屈光术后1个月,两组IOP、CCT及DA值无明显变化,差异均无统计学意义(P>0.05),SBK组A-time1值明显高于LASIK组,差异均有统计学意义(P<0.05)。结论中低度近视患者角膜屈光手术后角膜生物力学参数中IOP、CCT及A-time1有变化,DA值无变化。SBK与LASIK比较,前者A-time1较长。屈光手术后角膜生物力学参数的变化需进一步深入探讨研究。 To analyze the changes of biomechanical parameters about patients with low to moderate myopia after refractive surgery and discuss the safety and efficacy of refractive surgery with corneal visualization scheimpflug technology(Corvis ST)from the perspective of corneal biomechanical.Methods A total of 100 eyes from 100 patients with low to moderate myopia treated in Myopia laser center,the Affiliated Hospital of Inner Mongolia Medical University from March 2015 to October 2016 were selected randomly.According to operation method,the patients were divided into two groups,patients performed Sub-Bowman-Keratomileusis enrolled in SBK group and patients performed laser-assisted in situ keratectomy enrolled in LASIK group,with 50 patients in each group.And preoperative examination was performed and corneal biomechanics were tested by Corvis ST.Intraocular pressure(IOP),central corneal thickness(CCT),the first applanation time(A-time1)and deformation amplitude(DA)were observed in the two groups before and after operation and 1 month post-operation.Results Compared with pro-operation,patients in the two groups had significantly lower IOP,CCT and A-time1 after operation(P<0.05);but no significant difference was detected in DA before and after operation(P>0.05).Corneal biomechanics in the two groups before treatment have no difference(P>0.05);there were no significant differences in IOP,CCT and DA between SBK and LASIK group 1 month after operation(P>0.05);but A-time1 was higher in SBK group than that in LASIK group,and the difference was statistically significant(P<0.05).Conclusion There are differences in IOP,CCT and A-time1 between pro-operation and post-operation,but DA is not altered.From the perspective biomechanical parameters,SBK has higher A-time1 than LASIK.The changes of biomechanical parameters after refractive surgery should be studied and discussed in further study.
作者 关文英 赵海霞 GUAN Wenying;ZHAO Haixia(Myopia Laser Center,the Affiliated Hospital of Inner Mongolia Medical University,Inner Mongolia Autonomous Region,Huhhot 010050,China)
出处 《中国医药导报》 CAS 2018年第30期95-97,101共4页 China Medical Herald
基金 国家自然科学基金资助项目(81460090) 内蒙古自治区教育厅一般项目(NJZY16119)。
关键词 中低度近视 角膜屈光手术 角膜生物力学参数 可视化角膜生物力学分析仪 Low to moderate myopia Corneal refractive surgery Corneal biomechanical parameters Corneal visualization scheimpflug technology
作者简介 关文英(1983-),女,医学硕士;研究方向:眼视光学及角膜病;通讯作者:赵海霞(1968-),女,医学博士,主任医师,硕士生导师;研究方向:眼视光学及角膜病。
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