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骨填充网袋治疗老年骨质疏松性压缩骨折合并椎体内裂隙征 预览

A bone filling mesh container for treating senile osteoporotic vertebral compression fractures combined with intravertebral cleft sign
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摘要 背景:经皮椎体成形术治疗骨质疏松性椎体压缩骨折具有较好的疗效,但对于合并椎体裂隙征患者,较易发生骨水泥渗漏。目的:探讨骨填充网袋治疗老年骨质疏松性压缩骨折合并椎体内裂隙征的效果。方法:选择2017年10月至2018年7月青海大学附属医院收治的62例骨质疏松性压缩骨折合并椎体内裂隙征患者,年龄60-80岁,其中31例进行单侧椎体成形术骨水泥注入治疗(对照组),另31例进行骨填充网袋灌注骨水泥治疗(研究组),记录2组骨水泥渗漏情况、手术时间与透视次数。比较两组患者治疗前及治疗后7,30,60 d的目测类比评分与功能障碍ODI评分;通过X射线评估治疗前及治疗后7 d伤椎高度变化;采用SF-36量表评估患者治疗前与治疗后60 d的生活质量。结果与结论:①研究组手术时间与透视次数均少于对照组(P<0.05),研究组骨水泥渗漏率低于对照组(6%,39%,P<0.05);②两组治疗后7,30,60 d的目测类比评分与功能障碍ODI评分均较治疗前明显改善,研究组治疗后不同时间点的目测类比评分均低于对照组(P<0.05),两组治疗后不同时间点的功能障碍评分比较无差异(P>0.05);③两组治疗后7 d的伤椎高度明显高于治疗前(P<0.05),且研究组高于对照组(P<0.05);④两组治疗后60 d的生活质量均较治疗前明显改善(P<0.05),两组间比较无差异(P>0.05);⑤结果表明,相比于单侧椎体成形骨水泥注入治疗,骨填充网袋灌注骨水泥治疗老年骨质疏松性压缩骨折合并椎体内裂隙征,可降低骨水泥渗漏发生率、减轻疼痛、提高伤椎高度。 BACKGROUND:Percutaneous vertebroplasty is an effective method for osteoporotic thoracic vertebral compression fracture,but bone cement leakage is easy to occur in patients with intravertebral cleft.OBJECTIVE:To explore the therapeutic efficacy of bone-filling mesh containers in elderly patients with osteoporotic vertebral compression fractures combined with intravertebral cleft sign.METHODS:From October 2017 to July 2018,62 patients aged from 60 to 80 years with osteoporotic vertebral compression fractures combined with intravertebral cleft sign were admitted at the Affiliated Hospital of Qinghai University.Among them,31 cases were treated with unilateral percutaneous vertebroplasty(control group),and the other 31 cases were treated with bone-filling mesh containers(study group).The leakage of bone cement,the time of operation and the times of fluoroscopy were recorded in the two groups.The visual analogue scale score and Oswestry disability index score were compared between the two groups before and 7,30,60 days after treatment.The height changes of injured vertebrae were evaluated by X-ray before treatment and 7 days after treatment.The quality of life was evaluated by the MOS item short from health survey(SF-36)before and 60 days after treatment.RESULTS AND CONCLUSION:(1)The time of operation and the times of fluoroscopy in the study group were less than those in the control group(P<0.05),and the leakage rate of bone cement in the study group was lower than that in the control group(6%vs.39%,P<0.05).(2)The visual analogue scale score and Oswestry disability index score of the two groups were significantly improved at 7,30 and 60 days after treatment.The visual analogue scale scores of the study group were lower than those of the control group at different time points after treatment(P<0.05).There was no difference in Oswestry disability index scores between the two groups at different time points after treatment(P>0.05).(3)The height of injured vertebrae 7 days after treatment in both groups was significantly
作者 许勇 官众 李永霞 陈锋 Xu Yong;Guan Zhong;Li Yongxia;Chen Feng(Affiliated Hospital of Qinghai University,Xining 810000,Qinghai Province,China)
出处 《中国组织工程研究》 CAS 北大核心 2019年第10期1477-1482,共6页 Journal of Clinical Rehabilitative Tissue Engineering Research
基金 青海省卫计委指导项目(2016-wjzdx-50),项目负责人:许勇,项目名称:可注射性异烟肼磷酸钙纤维蛋白胶复合人工骨的生物相容性及骨缺损修复的实验研究.
作者简介 许勇,男,1984年生,青海省平安市人,汉族,副主任医师,硕士,主要从事脊柱外科、脊柱脊髓疾病研究;通讯作者:官众,教授,硕士生导师,青海大学附属医院,青海省西宁市810000
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