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吸入用布地奈德混悬液治疗小儿哮喘急性发作的效果及对肺功能的影响 预览

Effect of Budesonide in the treatment of acute attack of children with asthma and its effect on pulmonary function of patients
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摘要 目的探讨吸入用布地奈德混悬液治疗小儿哮喘急性发作的效果及对肺功能的影响。方法选取我院2016年3月~2018年1月收治的50例小儿哮喘急性发作的患儿作为研究对象,按照随机分组的方法分为观察组(25例)和对照组(25例)。对照组采用常规治疗,观察组采用吸入用布地奈德混悬液治疗,比较两组的治疗效果、临床症状改善时间,并比较两组治疗前后肺功能指标改善情况。结果观察组的治疗有效率为96.00%,明显高于对照组的72.00%,差异有统计学意义(P<0.05);观察组的咳嗽缓解时间、肺哮鸣音消失时间以及气促缓解时间明显短于对照组,治疗后观察组的肺功能各项指标数据也明显高于对照组,差异均有统计学意义(P<0.05)。结论对小儿哮喘急性发作的治疗,采用吸入用布地奈德混悬液效果较为理想,能快速缓解患儿的临床症状,改善其肺功能,加速患儿恢复,具有重要的临床意义。 Objective To investigate the effect of Budesonide suspension in the treatment of acute attack of asthma in children and its influence on pulmonary function. Methods Altogcther 50 children with acute attack of asthma in our hospital from March 2016 to January 2018 were selected and randomly divided into observation group (25 cases) and control group (25 cases). The control group was treated with routine treatment. The observation group was treated with Budesonide. The therapeutic effects of the two groups were compared. The improvement time of clinical symptoms and the improvement of pulmonary function before and after treatment were compared. Results The effective rate of the observation group was 96.00%, which was significantly higher than that of the control group (72.00%), the difference was statistically significant (P<0.05). The cough relief time, the disappearance time of wheezing sound and the relief time of shortness of breath was significantly shorter than that of the control group(P<0.05). After treatment, the indexes of lung function in the observation group were also significantly higher than those in the control group, the differences were statistically significant (P<0.05). Conclusion Budesonide is effective in the treatment of acute asthma in children. It can quickly relieve the clinical symptoms, improve the pulmonary function and accelerate the recovery of children with asthma.
作者 黄璜 HUANG Huang(Pediatric Respiratory Medicine, the Second Affiliated Hospital of Shantou University Medical College, Guangdong Province, Shantou 515000, China)
出处 《中国当代医药》 2019年第4期162-164,共3页 China Modern Medicine
关键词 吸入用布地奈德混悬液 小儿哮喘 急性发作 临床效果 肺功能影响 Budesonide Pediatric asthma Acute attack Clinical effect Pulmonary function effect
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