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拉贝洛尔联合硫酸镁治疗妊娠期高血压对妊娠结局的影响 预览

The pregnancy outcomes of labetalol combined with magnesium sulfate in the treatment of gestational hypertension
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摘要 目的探讨拉贝洛尔联合硫酸镁治疗妊娠期高血压孕妇对于妊娠结局的影响。方法2014年8月到2018年3月选择在本院产科建档分娩的妊娠期高血压孕妇120例作为研究对象,根据治疗方法的不同分为观察组40例与对照组80例,对照组采用硫酸镁治疗,观察组在对照组治疗的基础上给予拉贝洛尔治疗。结果治疗后两组的平均动脉压都呈现显著下降的趋势,差异有统计学意义(P<0.05),治疗后观察组也显著低于对照组,差异有统计学意义(P<0.05)。观察组的早产、胎儿窘迫、产后出血等发生率低于对照组,差异有统计学意义(P<0.05)。结论拉贝洛尔联合硫酸镁治疗妊娠期高血压孕妇可有效控制平均动脉压,改善妊娠结局,值得推广应用。 Objective To investigate the pregnancy outcomes of labetalol combined with magnesium sulfate in the treatment of gestational hypertension. Methods From August 2014 to March 2018, 120 pregnant women with pregnancy induced hypertension in obstetrics and gynecology were selected as the subjects. All the women were divided into the observation group of 40 cases and the control group 80 cases accorded to the different treatment methods, the control group were treated with magnesium sulfate, and the observation group were given the treatment of the labetalol combined with magnesium sulfate. Results After treatment, the mean arterial pressure of the two groups were showed significant downward trend and compared were significantly difference (P<0.05). After treatment, the observation group were also significantly lower than that of the control group and compared were significantly difference (P<0.05). The incidence of premature delivery, fetal distress and postpartum hemorrhage in the observation group were significantly lower than that in the control group and compared were significantly difference (P<0.05). Conclusion The labetalol combined with magnesium sulfate in the treatment of pregnant women with gestational hypertension can effectively control the mean arterial pressure and improve the outcome of pregnancy, which is worthy of popularization and application.
作者 田燕荣 王海平 李小菊 Tian Yanrong;Wang Haiping;Li Xiaoju(Department of Obstetrics and Gynecology,Miyun District Maternal and Child Health Hospital, Beijing, 101500, China)
出处 《当代医学》 2019年第3期12-14,共3页 Contemporary Medicine
关键词 拉贝洛尔 硫酸镁 妊娠期高血压 妊娠结局 Labetalol Magnesium sulfate Gestational hypertension Pregnancy outcome
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