Objective To observe the clinical efficacy of acupuncture plus Si jun zi decoction in treating hepatocirrhosis. Method Sixty-two patients with hepatocirrhosis were randomized into a treatment group of 28 cases and a control group of 34 cases. The control group was intervened by conventional medication, while the treatment group was additionally given acupuncture plus Si jun zi decoction. The indicators of liver fibrosis markers [laminin (LN), hyaluronic acid (HA) and type-III procollagen (PCⅢ)] and gastrointestinal symptom score in the two groups were observed before and at the end of the treatment. The indicators of liver function [albumin (ALB), total bilirubin (TBil), alanine transaminase (ALT) and aspartate transaminase (AST)], Child-Pugh score, the recovery of gastrointestinal function (recovery time of bowel sounds, extinction time of regurgitation and vomiting, and daily defecation frequency) and the incidences of complications in the two groups were also compared. Result The indicators of liver fibrosis markers (LN, HA and PCⅢ) and gastrointestinal symptom score all showed a significant change after the treatment in the two groups (P<0.01). After the treatment, the indicators of liver function (ALT, ALB,AST and TBil), Child-Pugh score, the indicators of liver fibrosis markers, gastrointestinal symptom score and the recovery of gastrointestinal function in the treatment group were significantly different from those in the control group (P<0.01). The incidences of complications was 10.7% in the treatment group and 38.2% in the control group, and there was a statistically significant difference between the two groups (P<0.05). Conclusion Acupuncture plus Si jun zi decoction is an effective method in treating hepatocirrhosis. It can effectively improve liver function in the patients, control the development of the disease, promote the recovery of gastrointestinal function, and reduce complications.
Shanghai Journal of Acupuncture and Moxibustion