期刊文献+

基于证据综合加权方法评价人参干预血糖、血压及血脂文献筛选研究

Study on Screening of Panax Ginseng in Blood Glucose, Blood Pressure and Blood Lipid Based on Comprehensive Weighted Evaluation of Literature Evidence
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摘要 目的:从中外文献中筛选人参对血糖、血压及血脂领域有较高证据效力的文献。方法:以人参降血糖、降血压、降血脂作用为主要研究目的,参考循证医学文献分级标准,对收集的临床、动物、体外试验文献予以证据分级,结合权重赋值计算并作归一化处理。结果:人参在血糖领域积累较高的证据效力,其次是血脂领域,血压领域的证据效力最低。证据效力较高的人参临床试验以复方研究为主,而证据效力较低的动物、体外实验以非复方研究为主。结论:基于文献证据综合加权评价方法对人参的功效证据筛选具有一定的参考价值,可为中医药数据分析挖掘提供方法与思路参考。 Objective: To screen panax ginseng with high evidences in blood glucose, blood pressure and blood lipid from Chinese and foreign literature. Methods: Referring to classification criterion of the evidence - based medicine, the sudies on clinical trials, animal studies and vitro experiments with the functions of reducing blood glucose, lowering blood pressure and lowering blood lipid were classified into diffferent grades, and the weight assignment method and unitary processing were used. Results: Panax ginseng had prominent effects on reducing blood glucose, followed by reducing blood lipid. And panax ginseng had the lowest effects on reducing blood pressure. The studies of panax ginseng with strong evidences in clinical trials were mainly about traditional Chinese medicine compound, while the studies of panax ginseng with low evidences in animal studies and vitro experiments were not about traditional Chinese medicine compound. Conclusions :The study had a certain reference value on the screening of panax ginseng in blood glucose, blood pressure and blood lipid based on comprehensive weighted evaluation of literature evidence, which can provide methods and thoughts for data mining and analysis of traditional Chinese medicine.
作者 杨丽丽 李文林 曾莉 李正钧 卞尧尧 宋宇 YANG Lili;LI Wenlin;ZENG Li;LI Zhengjun;BIAN Yaoyao;SONG Yu(School of First Clinical Medicine, Nanjing University of Chinese Medicine, Nanjing 210023 ,Jiangsu,China;Jingwen Library, Nanjing University of Chinese Medicine, Nanjing 210023 , Jiangsu,China;Management School, Lancaster University, Lancaster,United Kingdom LAI 4YW;School of Nursing, Nanjing University of Chinese Medicine, Nanjing 210023 ,Jiangsu,China)
出处 《中华中医药学刊》 CAS 北大核心 2019年第3期555-558,共4页 Chinese Archives of Traditional Chinese Medicine
基金 国家自然科学基金项目(81673982,81603529,81704084) 江苏省中医药管理局科技项目(YB2017002) 江苏省高校自然基金面上研究项目(16KJB360002) 江苏高校哲学社会科学研究基金项目(2017SJB0302) CALIS全国医学文献信息中心科研基金重点项目(CALIS-2018-01-006).
关键词 人参 血糖 血压 血脂 文献证据 综合加权评价 panax ginseng blood glucose blood pressure blood lipid literature evidence comprehensive weighted evaluation
作者简介 杨丽丽(1986-),女,江苏南通人,馆员,博士研究生,研究方向:中医药大数据分析;通讯作者:李文林(1973-),女,河南西华人,教授,硕士研究生导师,研究方向:中医药大数据分析.E-mail: njliwenlin@126. com.
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