Objective To study the effect of vertebroplasty combined with zoledronic acid on pain of spinal metastases. Methods Selected 104 cases of patients with spinal metastases who were treated in our hospital from January 2014 to December 2018, divided into two groups randomly. The control group was treated with vertebroplasty, while the observation group was treated with zoledronic acid. The analgesic effect, activity improvement effect and quality of life of the two groups were compared. Results The effective rate of pain relief in the observation group was 88.46%(46/52), which was significantly higher than control group 71.15%(37/52),P<0.05. The improvement rate of activity ability in the observation group was 86.54%(45/52), which was significantly higher than control group 69.23%(36/52),P<0.05. After treatment, the Kamofsky functional state scores of both groups were significantly increased(P<0.05), and the observation group was significantly higher(P<0.05). Conclusion Vertebroplasty combined with zoledronic acid has a good analgesic effect for patients with spinal metastases, which is helpful to improve their mobility and quality of life.
Foreign Medical Sciences:Section of Medgeography