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亚临床维生素A缺乏与重庆市及周边地区儿童生长痛的关系研究

Correlation analysis of marginal vitamin A deficiency and growing pains in children from Chongqing and surrounding areas
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摘要 目的:探讨亚临床维生素 A 缺乏与重庆市及周边地区儿童生长痛的关系,为生长痛儿童临床治疗提供依据。方法:对我院 2015 年 11 月至 2017 年 9 月临床上已排除其他疾病,诊断为生长痛且症状持续 6 个月以上的 111 名患儿,采用高效液相色谱法测定静脉血维生素A含量。其中男性患儿 53 例,女性 58 例;年龄:2.4~12.3 岁,平均 5.8 岁。采用同样的方法检测了 176例同期来我院健康体检儿童的维生素 A 含量,其中男 100 例,女 76 例;年龄 2.1~13.1 岁,平均 4.8 岁。结果:生长痛组 111 名中有 70 例(63.1%)为维生素 A 亚临床缺乏;体检组维生素A亚临床缺乏有 87 例(49.4%),比较 2 组数据差异有统计学意义(χ^2=5.104,P<0.05)。结论:亚临床维生素 A 缺乏与重庆市及周边地区儿童生长痛存在相关性。 Objective:To investigate the correlation of growing pains and marginal vitamin A deficiency in children from Chongqing and surrounding areas,and provide evidence for the clinical treatment of growing pains. Methods:From December 2015 to September 2017,111 children with growing pains in our hospital were chosen as observation group,including 53 boys and 58 girls with an aver- age age of 5.8 years old. And 176 checkup children at the same period were selected as control group,including 100 boys and 76 girls with an average age of 4.8 years old. The serum level of vitamin A was measured by high performance liquid chromatography,and was compared between the two groups. Results:There were 70 children of marginal vitamin A deficiency in the observation group,and 87 in the control group. The rate of marginal vitamin A deficiency was significantly different between the two groups(70/111 vs. 87/176, chi-square test,χ^2 =5.104,P<0.05). Conclusion:Marginal vitamin A deficiency may be associated with growing pains in children from Chongqing and surrounding areas.
作者 何金洲 刘星 张文兵 陈俊 陆干满 张润 周尹 He Jinzhou;Liu Xing;Zhang Wenbing;Chen Jun;Lu Ganman;Zhang Run;Zhou Yin(Ministry of Education Key Laboratory of Child Development and Disorders,China International Science and Technology Cooperation base of Child development and Critical Disorders,Chongqing Key Laboratory of Pediatrics)
出处 《重庆医科大学学报》 CAS CSCD 北大核心 2019年第5期638-641,共4页 Journal of Chongqing Medical University
基金 重庆市卫生和计划生育委员会重点资助项目(编号:[渝卫科教(2013)39 号 2013-1-029]) 国家临床重点专科建设项目(编号:[国卫办医函(2013)544]) 重庆市科学技术委员会民生资助项目(编号:[cstc2016shmszx130079])。
关键词 生长痛 维生素 A 亚临床缺乏 儿童 growing pains vitamin A marginal deficiency children
作者简介 何金洲,Email:799968616@qq.com,研究方向:小儿骨科;通信作者:刘星,Email:liuxingda@126.com.
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