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干细胞来源及内耳导入途径的研究进展 预览

Review of Stem Cell Sources and Inner Ear Transportation Pathways
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摘要 移植干细胞来源的选择、干细胞定向诱导分化、内耳移植途径的选择及移植后内耳功能恢复状况的评估是干细胞临床应用的研究热点。干细胞种类选择以及移植途径不同是影响内耳移植安全性及内耳功能恢复效果的两个重要因素,也是目前研究干细胞移植治疗耳聋的重点。本文就上述两者对感音神经性耳聋的治疗机制的相关文献进行综述,从而为耳聋传统治疗方案提供更新的指导。 Sources selection, directional differentiation and selection of inner ear transplantation approaches of stem cells, as well as evaluation of inner ear functional recovery after stem cell transplantation are hot topics of research on clinical application of stem cells. Stem cell types selection and the way of transplantation are two important factors affecting inner ear stem cell transplantation safety and inner ear function recovery. They are also the focus of current research on stem cell transplantation for deafness. This article reviews the literature on treatment mechanisms in sensorineural deafness, so as to provide new guidance for deafness treatment.
作者 田海月 向大伟 王新兰 钟翠萍 TIAN Haiyue;XIANG Dawei;WANG Xinlan;ZHONG Cuiping(Graduate School of Clinical College,Ningxia Medical University ,Yinchuan 750004;The 940th Hospital of Joint Logistics Support Force of Chinese People’s Liberation Army,Lanzhou 730050;The 940th Hospital of Joint Logistics Support Force of Chinese People’s Liberation Army Department of Otolaryngologyhead and neck surgery,Lanzhou 730050)
出处 《中华耳科学杂志》 CSCD 北大核心 2019年第3期421-427,共7页 Chinese Journal of Otology
基金 甘肃省重点研发计划项目(甘肃省科学技术厅),项目批准号:18YF1WA132 2018年度军队医学科技青年培育计划(军委后勤保障部卫生局),项目批准号:18QNP047.
关键词 干细胞 细胞移植 感音神经性耳聋 Stem Cells Cell Transplantation Sensorineural Hearing Loss
作者简介 田海月,医师,硕士研究生在读,研究方向:内耳干细胞移植和中耳炎临床防治研究;通讯作者:钟翠萍,Email:doctor.zhong@hotmail.com.
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