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早期量化功能锻炼对股骨干骨折患者凝血功能及炎性因子的影响观察 预览

Effects of early quantitative functional exercise on coagulation function and inflammatory cytokines of patients with femoral shaft fracture
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摘要 目的:研究早期量化功能锻炼对股骨干骨折患者凝血功能及炎性因子的影响。方法:选择2018年1月至2018年12月在我院进行治疗的100例股骨干骨折患者,随机分为两组,各50例。其中对照组患者采用常规护理,实验组患者常规护理基础上实施由护士指导进行股四头肌舒缩、上肢扩胸、抬臀运动等锻炼早期量化功能锻炼,每天锻炼15至30 min。采用酶联免疫吸附法(Enzyme linked immunosorbent assay,ELISA)检测白细胞介素1(Interleukin-1,IL-1)、胰岛素样生长因子-Ⅰ(Insulin-like Growth Factor-Ⅰ,IGF-Ⅰ)、白细胞介素6(Interleukin-6,IL-6)、C反应蛋白(C-reactive protein,CRP)、肿瘤坏死因子-α(Tumor necrosis factor-α,TNF-α)。采用全自动血液流变学分析仪检测2组患者治疗前后血浆黏度等血液流变学指标。结果:两组患者治疗后凝血功能相关指标均低于治疗前(P<0.05);且实验组更低(P<0.05);两组患者IL-1、IL-6、TNF-α均低于治疗前,IGF-Ⅰ高于治疗前;而治疗后实验组改善更为明显(P<0.05);实验组患者深静脉血栓发生率低于对照组(P<0.05)。结论:早期量化功能锻炼对股骨干骨折患者凝血功能及炎性因子改善效果明显,有利于患者康复,值得临床推广使用。 Objective:To investigate the effects of early quantitative functional exercise on coagulation function and inflammatory cytokinesofpatients with femoral shaft fractures.Method:All together,100 patients with femoral shaft fracture admitted to our hospital from January 2018 to December 2018 were enrolled,andrandomly divided into two groups with50 cases in each group.The control group was given routine care.The experimental group performed early quantitative functional exercise and received routine care.The expression of IL-1,IGF-Ⅰ,IL-6、TNF-α,blood rheology indicators such as plasma viscosity,and the incidence of deep venous thrombosis of the lower extremities of the two groups were measured and compared.Result:The coagulation function related indicators of the two groupsafter treatment waslower than that before treatment.The expression of IL-1,IL-6,andTNF-αwasdecreasedafter treatment.The expression ofIGF-I was increased after treatment.Conclusion:Early quantitative functional exercise can improve coagulation function and regulate the expression of inflammatory cytokinesin patients with femoral shaft fractures.
作者 于惠艳 Yu Hui-yan(Tianjin Hospital Traumatic pelvis,Tianjin 300211)
出处 《四川生理科学杂志》 2019年第2期132-134,137共4页 Sichuan Journal of Physiological Sciences
关键词 早期量化功能锻炼 股骨干骨折 凝血功能 炎性因子 Early quantitative functional exercise Femoral shaft fracture Coagulation Inflammatory factor influences
作者简介 于惠艳,女,护师,主要从事骨盆、股骨干等护理工作,Email:susuyy869868@163.com。
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