期刊文献+

利格列汀结合胰岛素治疗糖尿病肾病疗效观察 预览

Therapeutic Effect of Linagliptin Combined with Insulin on Diabetic Nephropathy
在线阅读 下载PDF
分享 导出
摘要 目的分析糖尿病肾病采用利格列汀联合胰岛素治疗的临床治疗效果。方法选择该院2017年1月-2018年12月收治的64例糖尿病肾病患者,根据治疗方法不同分组,对两组的血糖水平及肾功能改善情况进行对比分析。结果观察组经治疗后FBG、2hPG、HbA1c指标均显著低于对照组,差异有统计学意义(P<0.05);观察组治疗后Ccr(70.09±5.18)mL/min、M-Alb(263.77±29.50)mg/24h均与对照组差异有统计学意义(P<0.05)。结论利格列汀结合胰岛素在糖尿病肾病治疗中有血糖控制效果好,不加重对患者肾功能的损伤,也降低了胰岛素的用量,以避免低血糖发生。 Objective To analyze the clinical effect of linagliptin combined with insulin in the treatment of diabetic nephropathy.Methods 64 patients with diabetic nephropathy admitted to our hospital from January 2017 to December 2018 were enrolled.According to different treatment methods,the blood glucose levels and renal function improvement of the two groups were compared and analyzed.Results The FBG,2 hPG and HbA1c indexes in the observation group were significantly lower than those in the control group,the different was statistically significant(P<0.05).The observation group of Ccr(70.09±5.18)mL/min and M-Alb(263.77±29.50)mg/24 h were observed.There was a significant difference from the control group,the different was statistically significant(P<0.05).Conclusion Ligliptin combined with insulin has a good glycemic control effect in the treatment of diabetic nephropathy.It does not aggravate the damage of renal function in patients,and also reduces the amount of insulin to avoid hypoglycemia.
作者 王立全 李春燕 WANG Li-quan;LI Chun-yan(Department of Respiratory Endocrinology,Xuecheng People's Hospital,Zaozhuang,Shandong Province,277000 China)
出处 《糖尿病新世界》 2019年第9期187-188,共2页 Diabetes New World
关键词 糖尿病 肾病 利格列汀 胰岛素 疗效 Diabetes Kidney disease Linagliptin Insulin Efficacy
作者简介 王立全(1985-),男,山东枣庄人,本科,主治医师,主要从事临床工作。
  • 相关文献
投稿分析

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部 意见反馈