AIM: To evaluate the efficacy of FS-LASIK combined with rapid corneal collagen cross-linking in treatment of high myopia. METHODS: A prospective self-control study. Totally 42 patients (81 eyes) with high myopia treated by FS-LASIK combined with rapid corneal collagen cross-linking in our hospital from June to September 2017 were followed up for 6mo. The uncorrected visual acuity (UCVA),spherical equivalent (SE),corneal morphological parameters,corrected intraocular pressure and complications were observed. RESULTS: At 6mo after operation,the UCVA (LogMAR) increased from 1.44±0.18 before operation to -0.03±0.04, the SE degree reduced from -8.01±1.23D to -0.06±0.54D,the steepest corneal curvature (Steep K) decreased from 44.23±0.80D to 37.39±1.17D at 6mo after operation,the flattest corneal curvature (Fleep K) decreased from 42.87±0.61D before operation to 36.84±0.99D after operation. And the thinnest point thickness of cornea decreased from 525.33±30.42μm to 402.12±28.04μm,the corrected intraocular pressure decreased from 17.77±2.16mmHg to 16.69±0.41mmHg. There were no significant changes in the posterior surface height of thinnest cornea and the endothelial cell density. No corneal infections,serious non-infectious inflammation and complications related to corneal flaps were found during follow-up. CONCLUSION: FS-LASIK combined with rapid corneal collagen cross-linking is safe and effective in treatment of high myopia. The corneal morphology and refraction are relatively stable after surgery.
International Journal of Ophthalmology