Dear Editor,Recurrent pregnancy loss (RPL) in early pregnancy is a devastating problem for couples who want to become parents and a difficult challenge for their physician.RPL is also referred to as recurrent miscarriage or habitual abortion.It is defined as two or more consecutive clinical miscarriages (CMs) before 20 weeks of gestation (Practice Committee of the American Society for Reproductive Medicine,2012).
Science China: Life Science
the major program of the National Natural Science Foundation of China (81671456 to XML,81490742 to H.F.H.)
the Science and Technology 332 Commission of Shanghai (14DJ1400100 to H.F.H.)
the International Peace Maternity and Child Health Hospital Support Program (Y.T.T.)
the Medical and Health Science and Technology Plan of Zhejiang Province (2017KY078 to C.F.)
the Science and Technology Projects of Competent Departments (2017FZA7013 to P.P.L).