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丙泊酚复合氯化琥珀胆碱静脉麻醉在无抽搐电休克治疗中的临床效果分析 预览

Clinical Analysis of Intravenous Anesthesia with Propofol Combined with Acetylcholine Chloride in the Treatment of Electroconvulsive without Convulsion
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摘要 目的探讨对精神分裂症患者在实施无抽搐电休克(MECT)治疗期间丙泊酚复合氯化琥珀胆碱静脉麻醉的应用效果。方法选择该院2016年12月-2018年5月收治的82例精神分裂症患者作为实验对象;临床均选择MECT方法展开疾病治疗;保持3次/周频率展开治疗。期间对患者实施静脉全麻诱导操作,主要选择2.0 mg/kg丙泊酚复合1.0 mg/kg氯化琥珀胆碱药物完成,之后就患者的心率水平、血压水平、意识消失时间、血氧分压、自行行走时间、自主呼吸恢复时间以及副反应加以观察分析。结果给药前,所有精神分裂症患者的心率水平为(81.49±6.25)次/min;电击前,心率水平为(78.35±5.79)次/min;电击后,心率水平为(105.02±9.35)次/min;清醒后,心率水平为(81.13±6.39)次/min;电击后精神分裂症患者心率水平高于给药前、电击前以及清醒后尤为明显(P<0.05);患者意识消失时间为(50.25±10.79)min;自行行走时间为(24.49±9.32)min,自主呼吸恢复时间为(6.12±1.13)min。治疗期间,表现出头痛症状、呕吐症状以及嗜睡症状患者例数分别为2例、1例以及3例,总发生率为7.32%。结论精神分裂症患者在接受无抽搐电休克治疗期间,丙泊酚复合氯化琥珀胆碱静脉麻醉的应用,可以使得患者的痛苦感获得显著减轻,对于精神分裂症患者疗效提升以及病情好转可以获得显著促进效果。 Objective To investigate the effect of propofol combined with acetylcholine chloride intravenous anesthesia in patients with schizophrenia during the treatment of non-convulsive electroconvulsive(MECT). Methods Eighty-two patients with schizophrenia admitted to our hospital from December 2016 to May 2018 were selected as experimental subjects. The MECT method was selected for clinical treatment;the frequency was maintained at 3 times/week. During the period of intravenous anesthesia induction, the main choice was 2.0 mg/kg propofol combined with 1.0 mg/kg succinylcholine drug, and then the patient’s heart rate, blood pressure level,consciousness disappearance time, blood oxygen partial pressure Self-walking time, spontaneous breathing recovery time and side ef-fects were observed and analyzed. Results Before administration, the heart rate of all patients with schizophrenia was(81.49 ±6.25)times/min;before the shock, the heart rate was(78.35±5.79) times/min;after the shock, the heart rate was(105.02±9.35)times/min. After the waking, the heart rate level was(81.13±6.39) times/min;the heart rate level of patients with schizophrenia after electric shock was higher than that before administration, before the shock and after waking(P<0.05);the consciousness disappearing time(50.25±10.79) min;the self-traveling time was(24.49±9.32) min, and the spontaneous breathing recovery time was(6.12±1.13) min. During the treatment period, the number of patients with symptoms of headache, vomiting and drowsiness was 2 cases, 1 cases and 3 cases,respectively, with a total incidence of 7.32%. Conclusion The application of propofol combined with acetylcholine chloride intravenous anesthesia in patients with schizophrenia during the treatment of convulsion-free electroconvulsive therapy can significantly reduce the pain of patients, improve the efficacy of patients with schizophrenia and improve their condition, which can achieve good effect.
作者 马娇 MA Jiao(Department of Anesthesiology, Second People's Hospital of Honghe Prefecture, Honghe, Yunnan Province, 654399 China)
出处 《世界复合医学》 2019年第6期51-53,共3页 World Journal Complex Medicine
关键词 丙泊酚 氯化琥珀胆碱 静脉麻醉 无抽搐电休克 临床效果 Propofol Succinylcholine chloride Intravenous anesthesia No convulsion electroconvulsive Clinical effect
作者简介 马娇(1986-),女,回族,云南建水人,本科,主治医师,主要从事临床麻醉工作。
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