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枳术宽中胶囊对功能性消化不良伴焦虑抑郁患者的效果

Effect of Zhizhu Kuanzhong Capsule on functional dyspepsia patients with anxiety and depression
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摘要 目的观察功能性消化不良伴焦虑抑郁状态患者应用枳术宽中胶囊治疗的效果。方法随机将我院95例功能性消化不良伴焦虑抑郁状态患者分组,对照组47例予多潘立酮联合路优泰治疗,观察组48例予枳术宽中胶囊治疗,对比两组患者的临床症状、焦虑抑郁、疗效、不良事件及成本-效果。结果两组患者治疗后临床症状、HAMA、HDMD评分均较治疗前降低,组间对比没有差异(P>0.05),观察组不良事件发生率低于对照组(P<0.05),观察组成本-效果比值低于对照组。结论枳术宽中胶囊能够有效改善功能性消化不良伴焦虑抑郁状态患者的负性情绪,消除症状体征,安全性佳。 Objective To observe the effect Zhizhu Kuanzhong Capsule on functional dyspepsia patientswith anxiety and depression. Methods A total of 95 functional dyspepsia patients with anxiety and depression were randomly divided into two groups,47 patients in the control group were treated with domperidone combined with Luyoutai,while 48 patients in the observation group were treated with Qizhuanzhong Capsule. The clinical symptom scores,anxiety and depression were compared. Clinical efficacy,adverse events,and cost-effectiveness in two groups were compared. Results The clinical symptoms,HAMA and HDMD scores of the two groups were lower than those before treatment,there was no difference between two groups(P>0.05). The incidence of adverse events and compositioneffect ratioin in the observation group was lower than those in the control group(P<0.05). Conclusion Qizhu Kuanzhong Capsule can effectively improve the negative emotions in functional dyspepsia patients with anxiety and depression,eliminate symptoms and signs with good safety.
作者 侯云峰 李俊成 张静 HOU Yunfeng;LI Juncheng;ZHANG Jing(Central Hospital of Jiaozuo Coal Industry(Group)Co. ,Ltd,Jiaozuo 454150,China)
出处 《国际精神病学杂志》 2019年第4期721-723,共3页 Journal Of International Psychiatry
关键词 枳术宽中胶囊 功能性消化不良 焦虑 抑郁 Zhizhu Kuanzhong Capsule Functional dyspepsia Anxiety Depression
作者简介 第一作者及通讯作者:侯云峰(1982.09-),男,河南焦作人,本科,主治医师,研究方向:消化内科疾病中医诊疗。(Email:houyunfengjz@163.com).
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