Objective To observe the effect Zhizhu Kuanzhong Capsule on functional dyspepsia patientswith anxiety and depression. Methods A total of 95 functional dyspepsia patients with anxiety and depression were randomly divided into two groups,47 patients in the control group were treated with domperidone combined with Luyoutai,while 48 patients in the observation group were treated with Qizhuanzhong Capsule. The clinical symptom scores,anxiety and depression were compared. Clinical efficacy,adverse events,and cost-effectiveness in two groups were compared. Results The clinical symptoms,HAMA and HDMD scores of the two groups were lower than those before treatment,there was no difference between two groups(P>0.05). The incidence of adverse events and compositioneffect ratioin in the observation group was lower than those in the control group(P<0.05). Conclusion Qizhu Kuanzhong Capsule can effectively improve the negative emotions in functional dyspepsia patients with anxiety and depression,eliminate symptoms and signs with good safety.
Journal Of International Psychiatry
Zhizhu Kuanzhong Capsule