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肝癌患者血清5`—NT测定 被引量:3

THE DETERMINATION OF 5'-NUCLEOTIDASE IN PATIENTS WITH HEPATOCELLULAR CARCINOMA(HCC)
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摘要 本文对539例血清标本进行了5′-NT活性分析。在89例各种肝脏肿瘤中:原发性肝癌77例,其中α-FP阳性原发性肝癌68例,活性范围为41.6±25.8IU/L,α-FP阴性原发性肝癌9例,活性范围43.3±26.2IU/L;继发性肝癌7列,活性范围39.0±17.2IU/L(P【0.001);肝脏良性肿瘤5例,活性范围10.9±6.8IU/L(P】0.05)。另外还比较了血清5′-NT和ALP在诊断肝癌上的灵敏度。结果表明,血清5′-NT活性测定对于临床上肝癌的诊断具有一定价值,其灵敏度高于ALP。 The Determination of serum 5'-nucleotidase was made in 539 cases, 89 of which were found in association with the tumor of the liver 68 with primary HCC with AFP positive, 9 with primary HCC with AFP negative, 7 with secondary HCC and 5 with non-malignant tumor of the liver. The serum levels of 5'-nucleotidase activity were 41.6± 25.8 IU/L, 43.3±26.2 IU/L, 39.0±17.2 IU/L, ( P<0.001 )and 10,9±6.8 IU/L. (P>0.05), respectively. In contrast with ALP, the determination of serum 5'-nucleotidase activity is more sensitive in the diagnosis of HCC. We conclude that the detefmination of serum 5'-NT activity of patient with HCC is of significance to clinical diagnosis.
作者 郭华北 高学平 李詠 姜程茂 张启英 蒋秉坤 Guo Huabei, Gao Xueping, Li Yong, Jiang Chengmao, Zhang Qiying,Jiang Bingkun ( Department of Clinical Biochemistry, Bengbu Medical College,Anhui)
出处 《蚌埠医学院学报》 CAS 1992年第3期 163-164,共2页 Journal of Bengbu Medical College
关键词 5`-核苷酸酶 肝肿瘤 血清 serum 5' -nucleotidase ( 5' -NT ) serum alkaline phosphatase ( ALP ) hepatocellular carcinoma ( HCC )
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参考文献1

  • 1李影林主编..临床医学检验手册[M].长春:吉林科学技术出版社,1987:1173.

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