Objective To evaluate the MRI appearances of Leukemia with dura and intervertebral foramina infiltration,as well as the MRI diagnosis and differential diagnosis. Methods MRI findings and clinical data of 6 cases of clinicallyproven or pathologically-confirmed Leukemia which invaded intervertebral foramina were retrospective analysed. All cases underwent MRI scans of the spine. 5 patients with both pre-contrast and post-contrast MRI scan,1 patient only accepted precontrast MRI examination before local treatment. Results 1 case located at cervicothoracic spine showed an irregular paravertebral tumor,as well as both extradural and subdural masses of right paraspinal region and some right intraforaminal tumors. 4 cases showed extradural masses of thoracic spinal as well as unilateral or bilateral intervertebral foramina involvement. 1 case of right chest wall leukemia infiltration communicates with the epidural lesions through the right intervertebral foramen. 1 case appeared as lumbosacral epidural tumor involved bilateral intervertebral foramina along the nerve roots,and dural sac was mostly wrapped and narrowed. 4 lesions presented almost iso-intensity or slight hypo-intensity to soft tissue on T1 WI and iso-intensity or slight hyperintensity on T2 WI,and after gadolinium injection,they all enhanced uniformly. Other2 cases showed slight hypointensity on T1 WI and heterogeneous hyperintensity on T2 WI,and inhomogeneous enhancement.Conclusion The thoracic spinal canal is the most vulnerable spinal canal of Leukemia extramedullary infiltration,and in which epidural infiltration is the most common type,furthermore,epidural lesions often involve intervertebral foramina along the nerve roots.
Journal of Clinical Radiology