期刊文献+

早产儿校正胎龄40周肺功能检测及影响因素分析 预览

Lung Function of Preterm Infants at 40 Weeks of Gestational age and Analysis of In?uencing Factors
在线阅读 下载PDF
收藏 分享 导出
摘要 目的了解早产儿校正胎龄至40周时的肺功能情况,并探讨其影响因素。方法本次研究选取2018年1月至10月收治于聊城市人民医院新生儿重症监护室、并于校正胎龄40周至儿科门诊随访并行潮气呼吸肺功能检测的85例早产儿。并选取同期因非呼吸系统疾病住院的23例足月新生儿为对照组。(1)比较早产儿校正胎龄至40周时肺功能与足月儿对照组的差异;(2)填写早产儿住院期间的临床病例资料,分析围产期情况、出生时情况、合并症及治疗情况等15项指标对早产儿肺功能的影响。结果 (1)校正胎龄40周的早产儿肺功能的分析结果,达峰时间比(Tpef/Te)、达峰容积比(Vpef/Ve)、吸气峰流量(TPIF)、25%呼气流量(TEF25)、平均达峰时间(TpefMean)、平均达峰容积(VpefMean)、分钟通气量(MV)比足月对照组明显降低(P<0.05);(2)单因素分析结果表明,肺功能正常组胎龄(GA)、出生体重(BW)、1分钟Apgar评分(Apgar1)、5分钟Apgar评分(Apgar5)及出院时血红蛋白较异常组高,异常组达全肠道喂养时间较正常组长,与正常组相比,其动脉导管未闭(PDA)、胎膜早破、宫外生长发育迟缓(EUGR)、支气管肺发育不良(BPD)、新生儿呼吸窘迫综合征(RDS)发生率更高,正常组与异常组间的差异有统计学意义(P<0.05)。进一步采用logistic回归分析,得出导致肺功能异常的独立危险因素有EUGR、胎膜早破、PDA,肺功能的独立保护因素是GA、咖啡因及生后激素的使用,差异有统计学意义(P<0.05)。结论 (1)校正胎龄至40周时,早产儿与足月儿相比,仍存在阻塞性通气功能障碍,肺功能水平仍较差;(2)胎膜早破、PDA和EUGR是肺功能异常的独立危险因素,加强孕期保健,避免早产,加强呼吸、循环管理,保证良好的营养状态可以降低肺功能异常的发生。 Objective To understand the lung function of preterm infants at adjusted gestational age to 40 weeks,and to explore the influencing factors.Methods This study selected 85 premature infants admitted to the neonatal intensive care unit of Liaocheng people’s hospital from January to October,2018,who were followed up from 40 weeks of corrected gestational age to the outpatient department of pediatrics and tested for moisture respiratory and pulmonary functions.Twenty-three full-term newborns hospitalized for non-respiratory diseases in the same period were selected as the control group.(1)to compare the difference between the lung function of preterm infants and the control group of full-term infants from corrected gestational age to 40 weeks;(2)the clinical data of premature infants during hospitalization were filled in to analyze the influence of 15 indicators,including perinatal condition,birth condition,complications and treatment,on the lung function of premature infants.Results(1)Compared with the full-term control group,ratio of Tpef and Te(Tpef/Te),ratio of Vpef and Ve(Vpef/Ve),inspiratory peak flow rate(TPIF),25%expiratory flow rate(TEF25),mean time to peak expiratory flow(TpefMean),mean volume to peak expiratory flow(VpefMean)and minute ventilation volume(MV)of premature infants were all lower(P<0.05).(2)The results of univariate analysis showed that fetal age(GA),birth weight(BW),1 min Apgar score(Apgar1),5 min Apgar score(Apgar5)and hemoglobin at discharge were higher in the normal lung function group than in the abnormal group.The abnormal group had a longer total intestinal feeding time,higher incidence of patent ductus arteriosus(PDA),premature rupture of membranes,extrauterine growth retardation(EUGR),bronchopulmonary dysplasia(BPD),and neonatal respiratory distress syndrome(RDS),and the difference between the normal group and the abnormal group was statistically significant(P<0.05).Multivariate logistic regression analysis showed that EUGR,premature rupture of membranes and PDA were independent ris
作者 施敏 王钰 许平 高玲玲 韩梅盈 SHI Min;WANG Yu;XU Ping;GAO Ling-ling;HAN Mei-ying(NICU of liaocheng people’s hospital,Taishan Medical University,Liaocheng Shandong;NICU of liaocheng people’s hospital,Liaocheng Shandong)
出处 《世界最新医学信息文摘(电子版)》 2019年第35期21-23,共3页 World Latest Medicine
基金 聊城市人民医院早产儿RDS发生率及相关影响因素的调查分析(2018GSF118173).
关键词 早产 婴儿 呼吸功能试验 影响因素 Infant Premature Respiratory Function Tests Influencing factors
作者简介 施敏(1991-),在读硕士,新生儿重症;通讯作者:许平(1964-),女,教授,主任医师,硕士生导师。
  • 相关文献
投稿分析

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部 意见反馈