Objective To study the effect of Helicobacter pylori(HP)infection on acute exacerbation of chronic obstructive pulmonary disease(COPD).Methods A total of 86 patients were enrolled from those met COPD criteria and had ever admitted at the Fifth people’s Hospital of Yuhang District of Hangzhou during August 2015 to May 2017.13C breath test was performed in all patients.They were divided into two groups according to the conditions of patients at that time,Two groups werestable phase and acute exacerbation phase.Based on the results of 13C breath test,the patients were also divided into positive group and negative group,respectively.All patients were followed up for one year by telephone and read the medical record monthly.Which main included the onset times of acute exacerbation of COPD with in one year.Chi-square test was used during data analysis.Results There were 44 patients in acute exacerbation of COPD(AECOPD)group.Of them,9 patients were infected with Helicobacter pylori.The prevalence of Helicobacter pylori infection was 20.5%in patients with acute exacerbation of COPD in(AECOPD)group while 47.6%in patients with(COPD)in stable stage,and the positive rate of 13C breath test was 20.5%in patients with acute exacerbation of(COPD)while 47.6%in patients with stable(COPD).There was a significant difference between the two groups(P<0.05).However,there was no correlation between HP(Helicobacter pylori)infection and the frequency of acute exacerbation of COPD(P>0.05).Conclusion No correlation between Helicobacter pylori infection and acute exacerbation of COPD was found.
World Latest Medicine Information
Helicobacter pylori infection
Helicobacter pylori negative
13C breath test
Acute exacerbation of chronic obstructive Pulmonary Disease
Stable phase of chronic obstructive Pulmonary Disease