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恶性肿瘤患者血清对LAK细胞杀伤活性影响的研究 预览

THE RESEARCH OF SERUM IN MALIGNANT TUMOURS PATIENT EXERTION AN INFLUENCE ON LAK CELL LETHAL ACTIVITY
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摘要 用^3H—TdR掺入法测定了62例恶性肿瘤患者血清对LAK细胞杀伤活性的影响,并与20例健康成人血清对照,结果:20例健康成人组血清作用后的LAK细胞杀伤率均值为65.85±3.55%,62例恶性肿瘤患者组血清作用后的LAK细胞杀伤率均值为49.34±6.27%,两者有非常显著差异(P<0.01);48例有临床可见癌灶患者组血清作用后的LAK细胞杀伤率均值为49.60±6.60%,与健康成人组比较有非常显著差异(P<0.01);14例无临床可见癌灶患者组血清作用后的LAK细胞杀伤率均值为48.47±5.11%,与健康成人组比较有非常显著差异(P<0.01);与有临床可见癌灶患者组比较,无显著差异(P>0.05)。 ~.3H-TdR insert method was used for detection the serum of 62 malignant tumour patients which exerted an in-flunce on LAK cell LETHAL activity. The results showed: the mean of lethal rate was 65. 85 ?3. 55% in the group of 20 normal adults, the mean of lethal rate in the group of 62 malignan tumour patients was 49. 34?. 27%, both difference was significant (P<0. 01). The mean of lethal rate was 49. 60?6. 60% in the group of 48 patients whose tumour focus was clinic visible, com-pared with the normal group, the difference was obvious (P<0. 01) , the mean of lethal rate was 48. 47 ?5. 11% in the group of 14 patients who had not tumour focus of clinic visible, compared with the normal group, the difference was obvious (P<0. 01), but compared with the group of clinic visible tumour focus, it had not obvious difference (P>0. 05).
作者 罗泽民 林晓丽 叶宇钊 Luo Zeming, Lin Xiaoli, Ye Yuchao. The cancer clinical research group, Centre hospital of guangdong province agricultural reclamation, Zhanjiang 524002
出处 《临床肿瘤学杂志》 CAS 1996年第3期 35-37,共3页 Chinese Clinical Oncology
关键词 恶性肿瘤 血清 LAK细胞 免疫功能 临床资料 Malignant tumour, Serum/patient, LAK cell, Lethal activity,Restrain material
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