目的系统评价18F-FDGPET/CT对肝转移瘤的诊断价值。方法计算机检索Pubmed、EMbase、The Cochrane Library、Web of Science、中国生物医学文献数据库、万方数字化期刊数据库和中国期刊全文数据库及维普数据库中关于18F-FDGPET/CT诊断肝...目的系统评价18F-FDGPET/CT对肝转移瘤的诊断价值。方法计算机检索Pubmed、EMbase、The Cochrane Library、Web of Science、中国生物医学文献数据库、万方数字化期刊数据库和中国期刊全文数据库及维普数据库中关于18F-FDGPET/CT诊断肝转移瘤的文献,检索时间截止至2017年12月。由两位评价员按照预定的纳入与排除标准独立筛选文献、提取资料,按照QUADAS-2工具评价纳入研究的偏倚风险后,采用Stata12.0软件进行Meta分析。结果最终纳入15个研究,共1628个患者,1022个结节。Meta分析结果显示:以患者为单位,12篇(1473例患者)PET/CT研究的SEN合并=0.95(95%CI0.92-0.97)SPE合并=0.94(95%CI0.87-0.97)、AUC=0.98(95%CI0.97-0.99),以病灶为单位的6篇(1022例病灶)PET/CT研究的SEN合并=0.82(95%CI0.61-0.93),SPE合并=0.95(95%CI0.89-0.98)、AUC=0.97(95%CI0.95-0.98);亚组分析结果显示:各亚组PET/CT对肝转移瘤诊断的AUC进行比较,差异均无统计学意义(P>0.05)。结论18F-FDGPET/CT对肝转移瘤具有较高的诊断价值,尤其是对以病人为单位的病例具有更好的诊断敏感度。展开更多
Two metal-organic frameworks(MOFs) of formulae [Co7(L)3(4,4′-BPy)2(OH)2(H2O)6]·-4 H2O(1) and [Cd2(L)(2,2′-BPy)2]n(2, H4L = 5-(3,5-dicarboxybenzyloxy)-isophthalic acid,2,2′-BPy = 2,2?-bipyridine, 4,4′-BPy = 4,...Two metal-organic frameworks(MOFs) of formulae [Co7(L)3(4,4′-BPy)2(OH)2(H2O)6]·-4 H2O(1) and [Cd2(L)(2,2′-BPy)2]n(2, H4L = 5-(3,5-dicarboxybenzyloxy)-isophthalic acid,2,2′-BPy = 2,2?-bipyridine, 4,4′-BPy = 4,4′-bipyridine) were synthesized under solvothermal conditions. The structures of 1 and 2 were characterized by X-ray single-crystal diffraction analysis.In complex 1, six cobalt atoms were connected by oxygen atoms to form a defect dicubane structure. The defect dicubane structures were further linked by Co(4,4?-BPy) units to generate a3-D network structure. Compound 2 displays a 2-D chain structure. The photoluminescent property of complex 2 is investigated. The results show the exclusive luminescence emission bands being originated from intraligand π-π^* transitions.展开更多
为了提高盐碱地降水利用率,抑制化学(脱硫石膏)改良碱土过程中土壤盐分表聚及板结问题,该文以宁夏平罗县西大滩盐碱地试验站为例,设置了地膜秸秆复合覆盖(plastic and straw dual mulching,PSM)、地膜覆盖(plastic film mulching,P...为了提高盐碱地降水利用率,抑制化学(脱硫石膏)改良碱土过程中土壤盐分表聚及板结问题,该文以宁夏平罗县西大滩盐碱地试验站为例,设置了地膜秸秆复合覆盖(plastic and straw dual mulching,PSM)、地膜覆盖(plastic film mulching,PM)、秸秆覆盖(straw mulching,SM)和无覆盖常规种植(no mulching,CK)4个处理,探讨改良龟裂碱土过程中不同覆盖措施下旱地油葵的土壤水盐结构特征及其对产量的影响。结果表明,PSM处理有效提高了30~100 cm土层土壤贮水、持水能力,推迟油葵消耗相对深层60~100 cm土壤水分的时间;在30~90 cm土层,其水分活跃性显著高于其他处理;比单一覆盖抑盐效果佳,土壤盐分缓冲性增强,盐分表聚程度显著降低;同时能显著降低土壤容重,提高土壤孔隙度。PSM处理提高了油葵苗期存活率和产量,其较PM、SM处理和CK分别增产35.45%,120.15%,87.80%(P〈0.05);PSM处理较PM、SM处理和CK的降水利用效率分别提高了14.71%、86.45%和59.05%(P〈0.05),其水分利用效率分别比SM和CK提高了10.80%和32.71%。综上,地膜秸秆复合覆盖(PSM)可增强土壤保墒抑盐能力,改善作物根区土壤水盐环境,提高天然降水的生产潜力;促进碱土改良初期的保苗增产,提高经济效益。展开更多
文摘目的系统评价18F-FDGPET/CT对肝转移瘤的诊断价值。方法计算机检索Pubmed、EMbase、The Cochrane Library、Web of Science、中国生物医学文献数据库、万方数字化期刊数据库和中国期刊全文数据库及维普数据库中关于18F-FDGPET/CT诊断肝转移瘤的文献,检索时间截止至2017年12月。由两位评价员按照预定的纳入与排除标准独立筛选文献、提取资料,按照QUADAS-2工具评价纳入研究的偏倚风险后,采用Stata12.0软件进行Meta分析。结果最终纳入15个研究,共1628个患者,1022个结节。Meta分析结果显示:以患者为单位,12篇(1473例患者)PET/CT研究的SEN合并=0.95(95%CI0.92-0.97)SPE合并=0.94(95%CI0.87-0.97)、AUC=0.98(95%CI0.97-0.99),以病灶为单位的6篇(1022例病灶)PET/CT研究的SEN合并=0.82(95%CI0.61-0.93),SPE合并=0.95(95%CI0.89-0.98)、AUC=0.97(95%CI0.95-0.98);亚组分析结果显示:各亚组PET/CT对肝转移瘤诊断的AUC进行比较,差异均无统计学意义(P>0.05)。结论18F-FDGPET/CT对肝转移瘤具有较高的诊断价值,尤其是对以病人为单位的病例具有更好的诊断敏感度。
基金the National Natural Science Foundation of China (21763028)the Natural Science Foundation of Shaanxi Province (2018JM2055).
文摘Two metal-organic frameworks(MOFs) of formulae [Co7(L)3(4,4′-BPy)2(OH)2(H2O)6]·-4 H2O(1) and [Cd2(L)(2,2′-BPy)2]n(2, H4L = 5-(3,5-dicarboxybenzyloxy)-isophthalic acid,2,2′-BPy = 2,2?-bipyridine, 4,4′-BPy = 4,4′-bipyridine) were synthesized under solvothermal conditions. The structures of 1 and 2 were characterized by X-ray single-crystal diffraction analysis.In complex 1, six cobalt atoms were connected by oxygen atoms to form a defect dicubane structure. The defect dicubane structures were further linked by Co(4,4?-BPy) units to generate a3-D network structure. Compound 2 displays a 2-D chain structure. The photoluminescent property of complex 2 is investigated. The results show the exclusive luminescence emission bands being originated from intraligand π-π^* transitions.
基金福建省中青年教师教育科研项目(JA15224) Scientific Research Project Foundation of the Educational Committee of Fujian Province for Young and Middle Aged Teachers (JA15224)