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Recurrent abdominal liposarcoma: Analysis of 19 cases and prognostic factors 预览
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作者 Wei Lu James Lau +6 位作者 Mei-Dong Xu Yong Zhang Ying Jiang Han-Xing Tong Juan Zhu Wei-Qi Lu Xin-Yu Qin 《世界胃肠病学杂志:英文版(电子版)》 SCIE CAS 2013年第25期4045-4052,共8页
AIM: To evaluate the clinical outcome of re-operation for recurrent abdominal liposarcoma following multidis-ciplinary team cooperation. METHODS: Nineteen consecutive patients who had re-current abdominal liposarcoma... AIM: To evaluate the clinical outcome of re-operation for recurrent abdominal liposarcoma following multidis-ciplinary team cooperation. METHODS: Nineteen consecutive patients who had re-current abdominal liposarcoma underwent re-operation by the retroperitoneal sarcoma team at our institution from May 2009 to January 2012. Patient demographic and clinical data were reviewed retrospectively. Multidisciplinary team discussions were held prior to treatment, and re-operation was deemed the best treatment. The categories of the extent of resection were as follows: gross total resection (GTR), palliative resection and partial resection. Surgical techniques were divided into discrete lesion resection and combined contiguous multivisceral resection (CMR). Tumor size was determined as the largest diameter of the specimen. Patients were followed up at approximately 3-monthly intervals. For survival analysis, a univariate analysis was performed using the Kaplan-Meier method, and a multivariate analysis was performed using the Cox pro-portional hazards model. RESULTS: Nineteen patients with recurrent abdominal liposarcoma (RAL) underwent 32 re-operations at our institute. A total of 51 operations were reviewed with a total follow-up time ranging from 4 to 120 (47.4 ± 34.2) mo. The GTR rate in the CMR group was higher than that in the non-CMR group (P = 0.034). CMR was positively correlated with intra-operative bleeding (correlation coefficient = 0.514, P = 0.010). Six cases with severe postoperative complications were recorded. Patients with tumor sizes greater than 20 cm carried a significant risk of profuse intra-operative bleeding (P = 0.009). The ratio of a highly malignant subtype (de-differentiated or pleomorphic) in recurrent cases was higher compared to primary cases (P = 0.027). Both single-factor survival using the Kaplan-Meier model and multivariate analysis using the Cox proportional hazards model showed that overall survival was corre-lated with resection extent and pathological subtype (P 【 0.001 and P = 展开更多
关键词 Overall survival RECURRENT ABDOMINAL lipo-sarcoma Relapse-free interval
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提高对比的内视镜的 ultrasonography 的当前的地位和未来应用 预览
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作者 Hon Chi Yip Anthony Yuen Bun Teoh +1 位作者 Charing Ching Ning Chong James Yun Wong Lau 《世界胃肠内镜杂志:英文版(电子版)》 2014年第4期121-127,共7页
Endoscopic ultrasonography(EUS) is currently an in-tegral investigation of many gastrointestinal disorders.It has been shown to have a higher efficacy thanconventional computed tomography in detection andcharacteriza... Endoscopic ultrasonography(EUS) is currently an in-tegral investigation of many gastrointestinal disorders.It has been shown to have a higher efficacy thanconventional computed tomography in detection andcharacterization of small lesions especially in the pan-creas. Much effort has been put to further improvethe sensitivity, specificity and overall accuracy of EUS.One of the major advances is the utilization of contrastagents for better delineation of the vascularity and tis-sue perfusion of the target lesion. This article describesthe basic principles of ultrasound contrast agents andthe different modalities used in contrast-enhanced EUS(CE-EUS) including contrast-enhanced Doppler EUS(CED-EUS) and contrast-enhanced harmonic EUS(CEH-EUS). In addition, the current applications of contrastenhanced EUS in different gastrointestinal conditionswere discussed. Furthermore, the future developmentof hybrid approaches combining CE-EUS with other im-aging modalities and the potential therapeutic aspectof using it as a vector for drug delivery were also dis-cussed. 展开更多
关键词 ENDOSCOPIC ULTRASONOGRAPHY Contrastenhanced ENDOSCOPIC ULTRASONOGRAPHY ADVANCED ENDOSCOPIC ultrasonographic IMAGING
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外汇市场发展与金融稳定 预览
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作者 刘怡翔 《中国货币市场》 2004年第2期 26-31,共6页
香港金融市场发展的基本要素归纳起来是5P,也就是产品(Products)、定价(Pricing)、交易场所(Place)、交易平台(P1cqtrom)和市场参与者(Participants)。
关键词 外汇市场 金融稳定 香港 交易所市场 外汇清算平台 定价机制 货币局制度 港元 中国
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