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P2X7 receptor antagonism in amyotrophic lateral sclerosis 预览
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作者 Ronald Sluyter Rachael Bartlett +1 位作者 Diane Ly Justin J.Yerbury 《中国神经再生研究:英文版》 SCIE CAS CSCD 2017年第5期749-750,共2页
<正>Amyotrophic lateral sclerosis(ALS)is a rapidly progressive disorder characterized by the degeneration and subsequent loss of upper and lower motor neurons,resulting in reduced muscle function and paralysis(M... <正>Amyotrophic lateral sclerosis(ALS)is a rapidly progressive disorder characterized by the degeneration and subsequent loss of upper and lower motor neurons,resulting in reduced muscle function and paralysis(Mathis et al.,2017).Current therapies are limited to the oral administration of riluzole,which improves survival by only 3 months(Mathis et al.,2017).Thus,new therapies are urgently required to treat this neurodegenerative disor- 展开更多
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