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Impact of contrast-enhanced ultrasound in patients with renal function impairment 预览
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作者 Rossano Girometti Tiziano Stocca +2 位作者 Elena Serena Antonio Granata Michele Bertolotto 《世界放射学杂志:英文版(电子版)》 2017年第1期10-16,共7页
AIM To investigate the role of contrast enhanced ultrasound(CEUS) in evaluating patients with renal function impairment(RFI) showing:(1) acute renal failure(ARF) of suspicious vascular origin; or(2) suspicious renal l... AIM To investigate the role of contrast enhanced ultrasound(CEUS) in evaluating patients with renal function impairment(RFI) showing:(1) acute renal failure(ARF) of suspicious vascular origin; or(2) suspicious renal lesions.METHODS We retrospectively evaluated patients addressed to CEUS over an eight years period to rule-out vascular causes of ARF(first group of 50 subjects) or assess previously found suspicious renal lesions(second group of 41 subjects with acute or chronic RFI). After preliminary grey-scale and color Doppler investigation, each kidney was investigated individually with CEUS, using 1.2-2.4 m L of a sulfur hexafluoride-filled microbubble contrast agent. Image analysis was performed in consensus by two readers who reviewed digital clips of CEUS. We calculated the detection rate of vascular abnormalities in the first group and performed descriptive statistics of imaging findings for the second group.RESULTS In the first group, CEUS detected renal infarction orcortical ischemia in 18/50 patients(36%; 95%CI: 23.3-50.9) and 1/50 patients(2%; 95%CI: 0.1-12), respectively. The detection rate of infarction was significantly higher(P = 0.0002; Mc Nemar test) compared to color Doppler ultrasonography(10%). No vascular causes of ARF were identified in the remaining 31/50 patients(62%). In the second group, CEUS detected 41 lesions on 39 patients, allowing differentiation between solid lesions(21/41; 51.2%) vs complex cysts(20/41; 48.8%), and properly addressing 15/39 patients to intervention when feasible based on clinical conditions(surgery and cryoablation in 13 and 2 cases, respectively). Cysts were categorized Bosniak Ⅱ, ⅡF, Ⅲ and Ⅳ in 8, 5, 4 and 3 cases, respectively. In the remaining two patients, CEUS found 1 pseudolesion and 1 subcapsular hematoma.CONCLUSION CEUS showed high detection rate of renal perfusion abnormalities in patients with ARF, influencing the management of patients with acute or chronic RFI and renal masses throughout their proper characterization. 展开更多
关键词 提高对比的 ultrasonography 肾的功能缺陷 尖锐肾的失败 肾的梗塞 肾的损害 肾的包囊 Bosniak 分类
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