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Association between Sleep Disturbances and Cardiovascular Diseases: Results from NHANES 认领
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作者 Thierry P. Ayafor Jinkal Modi +2 位作者 Dayana A. Venkata Bolanle Bolaji Nicole C. Wright 《生物科学与医学(英文)》 2020年第4期1-11,共11页
Objectives: The relationship between sleep disturbances and cardiovascular disease (CVD) is not well established. This study assesses the association between sleep disturbances and CVD, and the effect of sleep duratio... Objectives: The relationship between sleep disturbances and cardiovascular disease (CVD) is not well established. This study assesses the association between sleep disturbances and CVD, and the effect of sleep duration on the relationship between sleep disturbances and CVD among adults in the United States (US). Design: Cross-sectional analysis. Setting: NHANES (National Health and Nutrition Examination Survey). Participants: A total of 5660 adults were included from the 2015-2016 cycle of the NHANES survey. Measurements: The main outcome was the presence of any CVD and included self-reported angina, congestive heart failure, coronary heart disease, hypertension and myocardial infarction. Associations between sleep disturbances and sleep duration with CVD were analyzed using logistic regression. Stratified models by sleep duration were used to assess effect modification. Results: We included 5660 participants (52.2% males), 32.7% of the participants reported having a disturbed sleep and 38% reported a CVD. Compared to those who did not report any sleep disturbances, those with sleep disturbance had 85% higher odds of CVD (OR 1.85, 95% CI 1.43 - 2.39). Similarly, there were 40% higher odds of CVD (OR 1.40, 95% CI 1.01 - 1.95) among those with shorter sleep duration compared with those that slept for 6 to 9hours. However, there was no evidence of effect modification by sleep duration. Conclusions: Our findings show that sleep disturbance is associated with higher odds of CVD. Clinicians and other healthcare providers need to consider the consequence of sleep disturbances and implement strategies in the treatment of patients with or at high risk of CVD. 展开更多
关键词 SLEEP DISTURBANCE CARDIOVASCULAR Disease SLEEP DURATION NHANES
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文章速递College Student Sleep Quality Following Sleep Classes 认领
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作者 Kathy Sexton-Radek 《健康(英文)》 2020年第10期1409-1414,共6页
Sleep hygiene and knowledge about sleep basics is unknown in college student populations. The college student population have abbreviated sleep due to social schedules and busy academic schedules. A measurement of sle... Sleep hygiene and knowledge about sleep basics is unknown in college student populations. The college student population have abbreviated sleep due to social schedules and busy academic schedules. A measurement of sleep hygiene and knowledge about sleep in the college student population indicates that there are varying levels along with sleep knowledge. The objective of the study was to examine young adult sleep quality because of providing an educative intervention. A sleep class of one hour provided once a week for ten weeks was provided following the administration of a ten-item sleep survey. Following the sleep class, the sleep survey was read ministered. Measures of central tendency and non-parametric analysis of nominal data were conducted. The results indicated two of the five cohorts had statistically significant differences. Further, the measures of sleep quality differed, statistically, for two of the cohorts receiving the classroom instruction. This research finding indicates a continued need to educate college student populations about their sleep health. 展开更多
关键词 Sleep Quality Sleep Sleep Deprivation
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基于微信小程序的“睡眠助手”设计与实现 认领
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作者 高群霞 胡镜鸿 《科技创新与应用》 2020年第34期31-32,共2页
近年微信小程序以便捷特性得到许多用户的喜爱,目前市面上虽然已有许多睡眠相关软件,但睡眠助手类小程序还很少或不成熟。从用户需求出发,设计并开发了一款基于微信小程序的“睡眠助手”软件,提供睡眠科普知识、睡眠量表打分、助眠音乐... 近年微信小程序以便捷特性得到许多用户的喜爱,目前市面上虽然已有许多睡眠相关软件,但睡眠助手类小程序还很少或不成熟。从用户需求出发,设计并开发了一款基于微信小程序的“睡眠助手”软件,提供睡眠科普知识、睡眠量表打分、助眠音乐、自动问答等功能。软件有助于科学了解睡眠、辅助改善睡眠,具有较好应用价值。 展开更多
关键词 睡眠 微信小程序 助眠音乐 睡眠量表 问答交互
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Association between non-alcoholic fatty liver disease and obstructive sleep apnea 认领
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作者 Ilaria Umbro Valerio Fabiani +2 位作者 Mario Fabiani Francesco Angelico Maria Del Ben 《世界胃肠病学杂志:英文版》 SCIE CAS 2020年第20期2669-2681,共13页
BACKGROUND Non-alcoholic fatty liver disease(NAFLD)is an emerging liver disease and currently the most common cause of incidental abnormal liver tests.The pathogenesis of NAFLD is multifactorial and many mechanisms th... BACKGROUND Non-alcoholic fatty liver disease(NAFLD)is an emerging liver disease and currently the most common cause of incidental abnormal liver tests.The pathogenesis of NAFLD is multifactorial and many mechanisms that cause fatty liver infiltration,inflammation,oxidative stress and progressive fibrosis have been proposed.Obstructive sleep apnea(OSA)may be linked with the pathogenesis and the severity of NAFLD.AIM To study the association between NAFLD and OSA considering also the efficacy of continuous positive airway pressure(CPAP)treatment.METHODS A Pub Med search was conducted using the terms"non-alcoholic fatty liver disease AND(obstructive sleep apnea OR obstructive sleep disorders OR sleep apnea)".Research was limited to title/abstract of articles published in English in the last 5 years;animal and child studies,case reports,commentaries,letters,editorials and meeting abstracts were not considered.Data were extracted on a standardized data collection table which included:First author,publication year,country,study design,number of patients involved,diagnosis and severity of OSA,diagnosis of NAFLD,patient characteristics,results of the study.RESULTSIn total,132 articles were initially retrieved on Pub Med search and 77 in the last five years.After removal of irrelevant studies,13 articles were included in the qualitative analysis.There was a total of 2753 participants across all the studies with a mean age between 42 and 58 years.The proportion of males ranged from21%to 87.9%and the mean body mass index ranged from 24.0 to 49.9 kg/m2.The results of this review showed an increased prevalence of NAFLD in patients with diagnosis of OSA,even in the absence of coexisting comorbidities such as obesity or metabolic syndrome.Furthermore,the severity of NAFLD is associated with the increase in OSA severity.Effective CPAP treatment,although not always decisive,may stabilize or slow NAFLD progression with benefits on metabolic and cardiovascular functions.CONCLUSION In NAFLD patients,although asymptomatic,it is recom 展开更多
关键词 Continuous positive air pressure Non-alcoholic fatty liver disease Nonalcoholic steatohepatitis Obstructive sleep apnea Obstructive sleep disorders Sleep apnea
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小学生同房间共眠状况及其影响因素研究 认领
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作者 李双艳 林艳媚 +2 位作者 林连虹 谢丽凯 张斌 《中国全科医学》 CAS 北大核心 2020年第33期4196-4202,共7页
背景儿童同房间共眠可能影响其睡眠质量,并引发一系列睡眠问题。目的调查广州市小学生同房间共眠状况,并分析其影响因素。方法根据广州市登记在册的小学名单,2014年应用随机数字法抽取1所省重点、1所市重点和1所区重点小学符合研究标准... 背景儿童同房间共眠可能影响其睡眠质量,并引发一系列睡眠问题。目的调查广州市小学生同房间共眠状况,并分析其影响因素。方法根据广州市登记在册的小学名单,2014年应用随机数字法抽取1所省重点、1所市重点和1所区重点小学符合研究标准的2462名在校小学生为研究对象。采用定式化睡眠问卷调查小学生最近1年的睡眠状况,问卷包括5部分:基本资料、家庭资料、父母资料、睡眠问题及儿童通常是否自己睡一间房?并依据最后一部分结果将儿童分为非共眠组和共眠组。问卷经学生带回家后与家长一起完成填写,1周内交回。结果共发放调查问卷2462份,回收有效问卷2345份,有效回收率为95.2%。2345名小学生中,男1218名,女1127名;年龄(9.5±1.7)岁;共眠1217名(51.9%),非共眠1128名(48.1%)。两组儿童年龄、近1年规律服药情况、单亲家庭情况、就寝环境、居住面积情况、家庭月收入情况比较,差异有统计学意义(P<0.05)。7~14岁儿童同房间共眠发生率随年龄增长而降低(χ2趋势=30.91,P<0.01)。非共眠组儿童母亲、父亲年龄均大于共眠组(P<0.05);两组儿童母亲不愿晨起情况比较,差异有统计学意义(P<0.05);两组儿童父亲文化程度、晨起口干、惊醒、不愿晨起、经常流汗、日间困倦、入睡困难、晨起头痛、睡眠感缺失情况比较,差异有统计学意义(P<0.05)。两组儿童打鼾、惊醒、不愿晨起、经常流汗、经常翻身、日间困倦、特殊俯睡体位、磨牙、尿床、呓语情况比较,差异有统计学意义(P<0.05)。多因素Logistic回归分析结果显示,年龄〔OR=0.713,95%CI(0.659,0.772)〕、单亲家庭〔OR=1.348,95%CI(1.098,1.655)〕、儿童打鼾〔OR=1.115,95%CI(1.020,1.219)〕、居住面积〔OR=0.908,95%CI(0.826,0.997)〕是小学生发生同房间共眠的影响因素(P<0.05)。结论广州市小学生与其家人同房间共眠状况较普遍(51.9%),低龄、单亲家庭、儿 展开更多
关键词 睡眠 睡眠障碍 儿童 同房间共眠 影响因素分析
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Sleep and Development 认领
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作者 Royi Gilad Colin Shapiro 《健康(英文)》 2020年第6期653-670,共18页
The early years of life are characterized by significant developmental processes of growth and differentiation in all physical systems and especially the central nervous system. Sleep plays a crucial role in cerebral ... The early years of life are characterized by significant developmental processes of growth and differentiation in all physical systems and especially the central nervous system. Sleep plays a crucial role in cerebral developmental processes and the accumulation of new abilities and skills. We review the current research evidence regarding the relationship between sleep (and its various components) and cerebral and physical developmental processes. Although sleep is an everyday physiological necessity, the ability to recognize it as a critical component of development may bring a different view towards sleep by parents, educators, and caregivers. This change might lead to a shift in individual and social attitudes aimed at enabling the necessary time and conditions for adequate sleep in children and adolescents to become the norm. These sets of values will then hopefully extend into adulthood, in which sleep also plays a crucial role in both physical and mental wellbeing. 展开更多
关键词 SLEEP DEVELOPMENT GROWTH
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Relationship between metabolic syndrome and hypercapnia among obese patients with sleep apnea 认领
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作者 Yuka Kimura Takatoshi Kasai +5 位作者 Yasuhiro Tomita Satoshi Kasagi Hisashi Takaya Mitsue Kato Fusae Kawana Koji Narui 《世界呼吸病学杂志》 2020年第1期1-10,共10页
BACKGROUND In the obese patient population,some patients have severe obstructive sleep apnea(OSA)with daytime hypoventilation.Such patients are generally identified on the basis of the presence or absence of daytime h... BACKGROUND In the obese patient population,some patients have severe obstructive sleep apnea(OSA)with daytime hypoventilation.Such patients are generally identified on the basis of the presence or absence of daytime hypercapnia,and the condition is called obesity hypoventilation syndrome.However,mechanisms for such daytime hypoventilation remain unclear.AIM To investigate metabolic syndrome and daytime hypercapnia association based on hypercapnia prevalence in obese OSA patients in a nested case-control study.METHODS Consecutive obese patients(body mass index≥30 kg/m2)who underwent polysomnography due to suspected OSA were included.Among them,patients with severe OSA(apnea hypopnea index≥30/h)were divided into two groups according to the presence or absence of hypercapnia during wakefulness(arterial partial pressure of carbon dioxide≥or<45 Torr,respectively).The characteristics and clinical features of these two groups were compared.RESULTS Among 97 eligible patients,25 patients(25.8%)had daytime hypercapnia.There were no significant differences in age,gender,body mass index,apnea-hypopnea index,and Epworth Sleepiness Scale scores between the two groups.However,patients with hypercapnia had a significantly lower arterial partial pressure of oxygen level(75.8±8.2 torr vs 79.9±8.7 torr,P=0.042)and higher arterial partial pressure of carbon dioxide level(46.6±2.5 torr vs 41.0±2.9 torr,P<0.001).Additionally,patients with hypercapnia were more likely to have metabolic syndrome(72.0%vs 48.6%,P=0.043)and a higher metabolic score(the number of satisfied criteria of metabolic syndrome).In multivariate logistic regression analysis,the presence of metabolic syndrome was associated with the presence of hypercapnia(OR=2.85,95%CI:1.04-7.84,P=0.042).CONCLUSION Among obese patients with severe OSA,26%of patients had hypercapnia during wakefulness.The presence of metabolic syndrome was independently correlated with the presence of daytime hypercapnia. 展开更多
关键词 Arterial partial pressure of carbon dioxide HYPERCAPNIA Metabolic SYNDROME Obesity HYPOVENTILATION SYNDROME Obstructive SLEEP APNEA SLEEP DISORDERED breathing
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磁珠耳穴疗法结合中医情志护理改善乳腺癌失眠患者睡眠质量的效果观察 认领
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作者 赵冬梅 申旭 《中华现代护理杂志》 2020年第4期505-509,共5页
目的探讨磁珠耳穴疗法结合中医情志护理改善乳腺癌失眠患者睡眠质量的效果。方法采用便利抽样法,选取2016年3月—2019年4月河北北方学院附属第一医院收治的乳腺癌失眠患者152例为研究对象,按入院顺序编号后采用随机数字表法分为观察组... 目的探讨磁珠耳穴疗法结合中医情志护理改善乳腺癌失眠患者睡眠质量的效果。方法采用便利抽样法,选取2016年3月—2019年4月河北北方学院附属第一医院收治的乳腺癌失眠患者152例为研究对象,按入院顺序编号后采用随机数字表法分为观察组、对照组各76例。对照组予以常规护理干预,观察组采用磁珠耳穴疗法结合中医情志护理。使用匹兹堡睡眠质量指数(PSQI)、疼痛视觉模拟评分(VAS)、汉密尔顿焦虑量表(HAMA)、汉密尔顿抑郁量表(HAMD)比较两组患者睡眠质量以及负性情绪。比较两组患者睡眠质量干预有效率。结果观察组睡眠质量干预有效率为90.79%(69/76),高于对照组的78.95%(60/76),两组比较差异有统计学意义(P<0.05);干预后1、3周观察组PSQI评分低于对照组,两组比较差异有统计学意义(P<0.05);干预后观察组VAS、HAMA、HAMD评分低于对照组,两组比较差异有统计学意义(P<0.05)。结论磁珠耳穴疗法结合中医情志护理可较好地改善乳腺癌失眠患者睡眠质量,减轻疼痛、负性情绪,值得在临床推广实践。 展开更多
关键词 乳腺肿瘤 睡眠 入睡和睡眠障碍 中医护理 情志护理 磁珠耳穴疗法
基于和谐护理理论的护理模式对胃癌根治术后患者睡眠和生活质量的影响 认领
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作者 常晶 韩晓霞 +1 位作者 宋伟华 巴楠 《癌症进展》 2020年第18期1940-1944,共5页
目的探讨基于和谐护理理论的护理模式对胃癌根治术后患者睡眠和生活质量的影响。方法采用随机数字表法将162例行胃癌根治术的患者随机分为观察组和对照组,各81例。对照组实施常规护理,观察组在此基础上实施基于和谐护理理论的护理。比... 目的探讨基于和谐护理理论的护理模式对胃癌根治术后患者睡眠和生活质量的影响。方法采用随机数字表法将162例行胃癌根治术的患者随机分为观察组和对照组,各81例。对照组实施常规护理,观察组在此基础上实施基于和谐护理理论的护理。比较两组患者干预前后匹兹堡睡眠质量指数(PSQI)、胃癌患者生活质量问卷(QLQ-ST022)评分。结果干预后,观察组PSQI量表各维度的评分均低于本组干预前,且均低于对照组(P﹤0.05)。干预后,两组患者QLQ-ST022中的各维度评分均低于本组干预前,且观察组QLQ-ST022中的吞咽困难、胃部疼痛、呃逆、饮食受限、焦虑、口干维度评分均低于对照组(P﹤0.05)。结论基于和谐护理理论的护理模式能够改善行胃癌根治术患者的睡眠和生活质量。 展开更多
关键词 和谐护理 胃癌根治术 睡眠 生活质量 匹兹堡睡眠质量指数
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A Novel Innovative Sleeping Mattress Could Possibly Save Lives and the National Economy: Small but Solid Evidence from a Medical Perspective 认领
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作者 Masaki Omura Nobuhiro Suetake +3 位作者 Kenichi Itao Takuji Yamaguchi Ailing Hu Hiroyuki Kobayashi 《健康(英文)》 2020年第7期811-827,共17页
The RAND Corporation reported that insufficient sleep causes an economic loss of $138 billion (2.92% of GDP) in Japan every year. In this study, we investigated the sleep improvement effect of a novel innovative sleep... The RAND Corporation reported that insufficient sleep causes an economic loss of $138 billion (2.92% of GDP) in Japan every year. In this study, we investigated the sleep improvement effect of a novel innovative sleeping mattress called “AiR SI” (Nishikawa Co., Ltd.) to find a simple method to solve the problem of sleep deprivation. We conducted a 2-week randomized, open-label, crossover, self-controlled study in 14 healthy adults in their 30s to 50s (control: 1 week, AiR SI: 1 week), with sleep quality as the primary endpoint as well as salivary components (cortisol, melatonin) and autonomic nervous function (sympathetic nerve, parasympathetic nerve) as secondary endpoints. Trends toward improvement in sleep were suggested for all the endpoints, regardless of differences in the subject background. The results suggested that the use of AiR SI for 1 week not only improved sleep but normalized both the endocrine and autonomic functions as well. We conclude that, by using a sleeping mattress with a high sleep improvement effect, the user may easily achieve higher labor productivity and have a lower mortality risk. Eliminating sleep deprivation with a sleeping mattress may lead to a reduction in national economic losses and ultimately produce significant economic effects. 展开更多
关键词 Sleeping Mattress Sleep Deprivation Mortality Risk Autonomic Nervous System Medical Economy
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Is the Shark Just Drifting, or Does It Take a Quick Nap? 认领
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作者 Erich K. Ritter 《动物科学期刊(英文)》 2020年第1期40-47,共8页
It is unknown if resting sharks can sleep, which is also true for gliding ones. Here, a videotaped bull shark is presented that drifted in an uncontrolled manner for 120 seconds while sinking with 0.1 m/second. Severa... It is unknown if resting sharks can sleep, which is also true for gliding ones. Here, a videotaped bull shark is presented that drifted in an uncontrolled manner for 120 seconds while sinking with 0.1 m/second. Several aspects are discussed to determine if the shown behavior reflects the commonly accepted definition of sleep. Additionally, the idea is also discussed if this state might reflect a “quiet waking state” instead of where the shark still maintained some vigilance despite its general appearance. 展开更多
关键词 DRIFTING MELATONIN PINEAL GLAND SHARK Sleep
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Approach to Paroxysmal Atrial Fibrillation Type Arrhythmia in a Cardiology Service: A Case Report 认领
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作者 Miriam Viviane Baron Luis Manuel Ley Dominguez +16 位作者 Carolina Paz Mohamad Isa Gabriela Di Lorenzo Garcia Scherer Michele Paula dos Santos Vitória Pereira Itaquy Talia Guimarã es dos Santos Julia Braga da Silveira Paulo Ricardo Martins Amanda Corrêa dos Santos Marcus Vinicius de Mello Pinto Janine Koepp Daiana Klein Weber Carissimi Joice Nedel Ott Carolina Gon?alves Pinheiro Nathália Ken Pereira Iketani Gabriela Feltez Bartira Ercília Pinheiro da Costa 《炎症(英文)》 2020年第2期9-17,共9页
Atrial fibrillation is a cardiac arrhythmia of high prevalence in the population, especially in the elderly. Its main electrical characteristics are the interval between two successive irregular R waves, absence of P ... Atrial fibrillation is a cardiac arrhythmia of high prevalence in the population, especially in the elderly. Its main electrical characteristics are the interval between two successive irregular R waves, absence of P waves and presence of f waves between QRS complexes. The most common symptoms of atrial fibrillation are irregular palpitations associated with dyspnea, dizziness, feeling tired, fatigue and general malaise, but not all patients have any symptoms. The present report presents the history of an elderly patient who arrived at the hospital’s emergency department with irregular heart rhythm and palpitations. The patient’s symptoms, associated with the electrocardiogram results, indicated paroxysmal atrial fibrillation. Electrical cardioversion was performed, and after, cardiac ablation via the femoral vein at the hospital’s cardiology service. There were no complications during the procedure. As a routine imaging exam after ablation, control esophagogastroduodenoscopy was requested to verify that there was no formation of atrio-esophageal fistula developed by the invasive ablation procedure and electrocardiogram, which showed normal sinus rhythm. The patient remained in the cardiac intensive care unit for observation for 24 hours. After the electrical cardioversion and catheter ablation procedures, the patient improved his clinical picture of atrial fibrillation and was discharged after 24 hours of hospitalization. He received treatment to perform at home, to reduce acid reflux into the esophagus and to prevent thrombosis. He did not present pulmonary thromboembolism after hospital discharge. It is believed, therefore, that this form of treatment and management of paroxysmal atrial fibrillation is effective for the solution of the proposed problem and can also serve as a reference for other professionals within the cardiology service. 展开更多
关键词 Atrial FIBRILLATION Electrical CARDIOVERSION CATHETER Ablation Hypertension OBSTRUCTIVE Sleep APNEA Syndrome
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Anxiolytic Effect of Increased NREM Sleep after Acute Social Defeat Stress in Mice 认领
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作者 Xiang Feng Hui-Ying Zhao +4 位作者 Yu-Jin Shao Hui-Fang Lou Li-Ya Zhu Shumin Duan Yan-Qin Yu 《神经科学通报:英文版》 SCIE CAS CSCD 2020年第10期1137-1146,共10页
Social defeat stress(SDS)plays a major role in the pathogenesis of psychiatric disorders like anxiety and depression.Sleep is generally considered to involve recovery of the brain from prior experience during wakefuln... Social defeat stress(SDS)plays a major role in the pathogenesis of psychiatric disorders like anxiety and depression.Sleep is generally considered to involve recovery of the brain from prior experience during wakefulness and is altered after acute SDS.However,the effect of acute SDS on sleep/wake behavior in mice varies between studies.In addition,whether sleep changes in response to stress contribute to anxiety is not well established.Here,we first investigated the effects of acute SDS on sleep/wake states in the active period in mice.Our results showed that total sleep time(time in rapid eyemovement[REM]and non-REM[NREM]sleep)increased in the active period after acute SDS.NREM sleep increased mainly during the first 3 h after SDS,while REM sleep increased at a later time.Then,we demonstrated that the increased NREM sleep had an anxiolytic benefit in acute SDS.Mice deprived of sleep for 1 h or 3 h after acute SDS remained in a highly anxious state,while in mice with ad libitum sleep the anxiety rapidly faded away.Altogether,our findings suggest an anxiolytic effect of NREM sleep,and indicate a potential therapeutic strategy for anxiety. 展开更多
关键词 Social defeat stress SLEEP Sleep deprivation ANXIETY Anxiolytic effect
丙泊酚与睡眠障碍 认领
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作者 王培 陈怀龙 +1 位作者 秦伟伟 王明山 《国际麻醉学与复苏杂志》 CAS 2020年第2期208-211,共4页
睡眠是维持人体正常生理功能的一个重要生理活动,随着人们生活节奏的加快,睡眠障碍的人数也在逐渐增多。目前许多研究表明全身麻醉药可以通过作用于睡眠‐觉醒环路引起意识消失,从而在短时间内对人体的睡眠产生一定的影响。丙泊酚是全... 睡眠是维持人体正常生理功能的一个重要生理活动,随着人们生活节奏的加快,睡眠障碍的人数也在逐渐增多。目前许多研究表明全身麻醉药可以通过作用于睡眠‐觉醒环路引起意识消失,从而在短时间内对人体的睡眠产生一定的影响。丙泊酚是全身麻醉药的一种,进一步观察和研讨丙泊酚对睡眠障碍患者产生的影响,有助于了解丙泊酚对患者预后和康复产生的影响,但是丙泊酚与睡眠障碍关系的研究却少之又少。文章通过介绍睡眠产生的机制和调节因素、睡眠障碍产生的机制和影响因素,总结丙泊酚对睡眠的影响及导致意识消失的分子靶点,综述丙泊酚对睡眠障碍可能产生的影响及机制。 展开更多
关键词 丙泊酚 麻醉药 全身 意识消失 睡眠 睡眠障碍
A review on the effects of sleep duration on hypertension 认领
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作者 Toluwase Adewunmi 《TMR生命研究》 2020年第1期39-43,共5页
Blood pressure and sleep,the two important indicators of health outcomes,are of increasing public health importance.There are variations in the blood pressure parameters during sleep and association exists between sle... Blood pressure and sleep,the two important indicators of health outcomes,are of increasing public health importance.There are variations in the blood pressure parameters during sleep and association exists between sleep and elevated blood pressure.The absence of nocturnal dipping of the blood pressure also increases cardiovascular risk.Sleep duration has been defined as normal(7-8 hours of sleep),short≤6 hours and long sleep≥9 hours.Short sleep duration is associated with hypertension especially during middle age and women who are deprived of sleep particularly post-menopausal had a higher risk of hypertension than men.Methodological concerns exist in the measurement of sleep duration,although both subjective and objective assessment of sleep duration showed an association with hypertension.Shorter sleep duration is believed to result in prolonged exposures to elevated sympathetic activity and psychosocial stressors.There is no enough evidence to support this statement for longer sleep duration.Long and short sleep duration are associated with the incidence of hypertension across most age groups.Relationships of short sleep are stronger among women and young adults compared to long sleep duration which is stronger among the elderly. 展开更多
关键词 HYPERTENSION SLEEP DURA tion BLOOD PRESSURE SLEEP
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神经递质在OSA相关觉醒中可能发挥的作用 认领
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作者 卢静成 杨立新 +1 位作者 赵花 周宁 《世界睡眠医学杂志》 2020年第6期1115-1116,共2页
睡眠对于人类的一生来说,是必不可少的组成部位,人生有三分之一的时间处于睡眠状态,许多疾病也跟睡眠有关。但是睡眠-觉醒到底是如何控制的,至今尚不明确。但可以肯定的是睡眠-觉醒系统是由多种神经肽递质参与的,其中可分为促睡眠类和... 睡眠对于人类的一生来说,是必不可少的组成部位,人生有三分之一的时间处于睡眠状态,许多疾病也跟睡眠有关。但是睡眠-觉醒到底是如何控制的,至今尚不明确。但可以肯定的是睡眠-觉醒系统是由多种神经肽递质参与的,其中可分为促睡眠类和促觉醒类。二者共同合作,来维持睡眠-觉醒系统。目前发现觉醒在阻塞性睡眠呼吸暂停(OSA)发病及预后过程中的作用越来越受到重视,而OSA相关觉醒的具体产生机制尚不明确。本综述重点概括了可能参与OSA相关觉醒的神经递质。 展开更多
关键词 睡眠 觉醒 阻塞性睡眠呼吸暂停 5-羟色胺 神经肽S 神经肽Y γ-氨基丁酸 食欲素 儿茶酚胺 黑色素浓缩激素 乙酰胆碱
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Survey of the Sleep Quality of Medical Staff in a Grade A Tertiary Hospital during the Novel Coronavirus Pneumonia Outbreak 认领
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作者 Qiugui Huang Jian Yu +2 位作者 Linjun Liang Xiaofang Zhang Yuyao Liu 《临床护理研究》 2020年第5期56-60,共5页
This study aimed to investigate the sleep quality of medical staff in China who are combatting novel coronavirus pneumonia(COVID-19).To perform this,a survey of 127 medical staff from three separate wards(the general ... This study aimed to investigate the sleep quality of medical staff in China who are combatting novel coronavirus pneumonia(COVID-19).To perform this,a survey of 127 medical staff from three separate wards(the general ward,isolation ward,and fever clinic)of a Grade A tertiary hospital in China was conducted.The survey questionnaire measured general characteristics and included the Pittsburgh Sleep Quality Index(PSQI).We consequently found that global PSQI scores differed significantly between the different wards(χ2=44.561,P<0.001).Whilst the medical staff in the general ward did not report any sleep disturbances,those in the isolation ward and the fever clinic both exhibited various degrees of sleep disturbance(global PSQI score>7).Medical staff in the isolation ward had the worst sleep quality(mean rank=91.74),followed by those in the fever clinic(mean rank=70.52)and the general ward(mean rank=39.10),respectively.The primary sleep disturbances reported by the medical staff from the isolation ward included difficulty falling asleep(24 cases,71.42%),waking early or at night(28 cases,80%),and nightmares(18 cases,51.42%).In addition,31.42%(11 cases)of the medical staff from the isolation ward had less than six hours of sleep a night,and 65.71%(23 cases)felt that their sleep quality was poor;meanwhile,for the staff from the fever clinic these ratios were 16.67%(seven cases)and 33.33%(14 cases),respectively.In contrast,among medical staff in the general ward,98%(49 cases)reported sleeping for more than six hours a night,and 96%felt that their sleep quality was good.In conclusion,of the medical staff providing treatment for COVID-19,those in isolation wards and fever clinics are more likely to experience sleep disturbances. 展开更多
关键词 Novel coronavirus pneumonia medical staff sleep quality Pittsburgh Sleep Quality Index
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Effect of motivational interviewing on postoperative weight control in patients with obstructive sleep apnea-hypopnea syndrome 认领
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作者 Xiang-Hong Sun Peng-Shi Xue +1 位作者 Xiang-Xiu Qi Ling Fan 《世界临床病例杂志》 SCIE 2020年第15期3209-3217,共9页
BACKGROUND Obesity is an important factor to cause the obstructive sleep apnea-hypopnea syndrome(OSAHS).Higher body mass index(BMI)often results in more severe OSAHS.Currently,the common measures for controlling the w... BACKGROUND Obesity is an important factor to cause the obstructive sleep apnea-hypopnea syndrome(OSAHS).Higher body mass index(BMI)often results in more severe OSAHS.Currently,the common measures for controlling the weight mainly include diet control,increase exercise and so on.Motivational interviewing(MI)could explore the patient’s internal state and make the patient realize his/her ambivalence,resulting in the change in his/her behavior.This process emphasizes respecting the patient’s autonomy.AIM To evaluate the effect of MI on the weight control of patients with OSAHS.METHODS A randomized controlled study was conducted in 100 obese OSAHS patients undergoing surgical treatment at Shengjing Hospital of China Medical University.The patients were divided into an intervention group and a control group,with 50 cases each.The control group was given routine health education after the operation;in addition to the regular health education,the intervention group was given MI according to a predetermined plan.Obesity-related indicators,postoperative complications,and the sleep status of both groups were evaluated before and 6 mo after the intervention.RESULTS Patients in the intervention group had significantly improved body weight,BMI,and waist and neck circumferences compared with patients in the control group(P<0.05).Regarding complications at 6 mo after operation,the incidence of cough and reflux in patients in the intervention group was significantly lower than that in the control group(P<0.05).In addition,the Epworth Sleepiness Scale and Self-Rating Scale of Sleep scores of patients in the intervention group were significantly lower than those in the control group,and the sleep status of patients in the intervention group was improved(P<0.05).CONCLUSION MI intervention has a significant advantage over postoperative routine health education.It can greatly change the lifestyle,further control the postoperative weight,reduce the occurrence of complications,improve the quality of sleep,and improve long-term posto 展开更多
关键词 Obstructive sleep apnea-hypopnea syndrome POSTOPERATIVE Weight control Motivational interview Quality of sleep PATIENTS
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Photoacoustic treatment mitigates cognitive dysfunction in a model of sleep-wake rhythm disturbance 认领
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作者 Fang Xing Xin Fang +5 位作者 Xiang-Dan Gong Xin Zhao Ying Du Zheng-Liang Ma Xiao-Ping Gu Tian-Jiao Xia 《中国神经再生研究:英文版》 SCIE CAS CSCD 2020年第6期1094-1101,共8页
Sleep-wake rhythm disturbances,which are characterized by abnormal sleep timing or duration,are associated with cognitive dysfunction.Photoacoustic treatments including light and sound stimulation have been found to b... Sleep-wake rhythm disturbances,which are characterized by abnormal sleep timing or duration,are associated with cognitive dysfunction.Photoacoustic treatments including light and sound stimulation have been found to be effective in modulating sleep patterns and improving cognitive behavior in abnormal sleep-wake pattern experiments.In this study,we examined whether light and sound interventions could reduce sleep-wake pattern disturbances and memory deficits in a sleep rhythm disturbance model.We established a model of sleep rhythm disturbance in C57 BL/6 J mice via a sleep deprivation method involving manual cage tapping,cage jostling,and nest disturbance.We used a Mini Mitter radio transmitter device to monitor motor activity in the mice and fear conditioning tests to assess cognitive function.Our results indicated that an intervention in which the mice were exposed to blue light(40-Hz flickering frequency)for 1 hour during their subjective daytime significantly improved the 24-hour-acrophase shift and reduced the degree of memory deficit induced by sleep deprivation.However,interventions in which the mice were exposed to a 40-Hz blue light at offset time or subjective night time points,as well as 2 Hz-blue light at 3 intervention time points(subjective day time,subjective night time,and offset time points),had no positive effects on circadian rhythm shift or memory deficits.Additionally,a 2000-Hz sound intervention during subjective day time attenuated the24-hour-acrophase shift and memory decline,while 440-Hz and 4000-Hz sounds had no effect on circadian rhythms.Overall,these results demonstrate that photoacoustic treatment effectively corrected abnormal sleep-wake patterns and cognitive dysfunction associated with sleep-deprivation-induced disturbances in sleep-wake rhythm.All animal experiments were approved by the Experimental Animal Ethics Committee of Drum Tower Hospital Affiliated to the Medical College of Nanjing University,China(approval No.20171102)on November20,2017. 展开更多
关键词 circadian RHYTHM cognitive impairment fear conditioning light INTERVENTION PHOTOACOUSTIC treatment RHYTHM DISTURBANCE RHYTHM shift sleep DEPRIVATION SLEEP-WAKE RHYTHM sound INTERVENTION
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Effect of Huatan Jieyu granules in treatment of Parkinson’s disease patients with sleep disorder identified as symptom pattern of phlegma-heat-stirring wind 认领
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作者 Liu Meijun Hu Chongshan +8 位作者 Zhang Yaodan Li Qizheng Zhang Qi Fang Yu Sun Honghui Hou Xiaolin Jin Shuoguo Tao Liangjing Yang Dongdong 《中医杂志:英文版》 SCIE CAS CSCD 2020年第3期461-466,共6页
OBJECTIVE: To investigate the safety and efficacy of Huatan Jieyu granules in treatment of Parkinson’s disease(PD) patients with sleep disorder identified as symptom pattern of phlegma-heat-stirring wind in terms of ... OBJECTIVE: To investigate the safety and efficacy of Huatan Jieyu granules in treatment of Parkinson’s disease(PD) patients with sleep disorder identified as symptom pattern of phlegma-heat-stirring wind in terms of the theory of Traditional Chinese Medicine.METHODS: In total, 107 Parkinson’s disease patients with sleep disorders identified as symptom pattern of phlegma-heat-stirring wind were selected and randomly divided into the experimental group(55 cases) and the control group(52 cases).Both groups were given basic treatment with prednisone. The experimental group of patients was treated with Huatan Jieyu granules and the control group of patents was treated with only the basic treatment. Treatment lasted for 4 weeks. Sleep polygraph were recorded before the study as well as 3 months and 6 months after treatment.RESULTS: After treated with Huatan Jieyu granules,the total sleep time, and the percentage of non rapid eye movement 2(NREM 2), non rapid eye movement 3(NREM 3) and rapid eye movement(REM)sleep period increased significantly, while the percentage of NREM1 sleep period decreased significantly compared with before treatment(P < 0.05).CONCLUSION: The treatment of PD patients with sleep disorder by Huatan Jieyu granules can improve their sleep structure and their sleep quality. 展开更多
关键词 Parkinson disease Sleep disorder Phlegma-heat-stirring wind Sleep polygraph Huatan Jieyu granules
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