基金The authors thank the staff of the Recovery Medical Technology Development Co. for their important assistance in human blood sample collection and storage. The authors are also grateful to the anonymous reviewers for their constructive comments. This study was supported by the National Natural Science Foundation of China （Grant Nos. 81670462 and 81422006） to QC and the Fundamental Research Funds for Central Universities of China （Grant No. BMU2017YJ004） to YZ （Yuan Zhou）.