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Approach to 2′-(Dialkylamino)-1-alkyl-4′H-spiro[indoline-3,5′-oxazole]-2,4′-diones and 1,3-Oxazin-4-ones via Cyclization of Vilsmeier Salts withα-Hydroxy andβ-Carbonyl Amides
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作者 DAI Jianan LIU Bengen +4 位作者 WEI Zhonglin CAO Jungang LIANG Dapeng DUAN Haifeng LIN Yingjie 《高等学校化学研究:英文版》 SCIE CAS CSCD 2019年第2期216-220,共5页
A straiglitforward and efficient synthetic method of 2′-(dialkylammo)-l-alkyl-4′H-spiro[indoline-3,5′-oxazole]-2,4′-diones and 2-(dialkylamino)-5,6-dihydro-4H-naphtho[2,1-e][1,3]oxazin-4-one-derivatives have been ... A straiglitforward and efficient synthetic method of 2′-(dialkylammo)-l-alkyl-4′H-spiro[indoline-3,5′-oxazole]-2,4′-diones and 2-(dialkylamino)-5,6-dihydro-4H-naphtho[2,1-e][1,3]oxazin-4-one-derivatives have been developed from a-hydroxy andβ-carbonyl amides and various Vilsmeier salts.A wide range of heterocyclic compounds were obtained in excellent yields(up to 97%),which will provide promising candidates lor chemical biology and drug discovery. 展开更多
关键词 SPIROOXINDOLE unit 2-Oxazolin-4-ones CORE STRUCTURE 3-Oxazin-4-ones CORE STRUCTURE
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