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Bacteriological Profile of Pneumopathies in Chronic Renal Failure at the University Hospital Center of Point-G in Mali 认领
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作者 Seydou Sy Magara Samaké +11 位作者 Hamadoun Yattara Moctar Coulibaly Ba Oumou Diallo Aboubacar Sidiki Fofana Djénéba Diallo Atabieme Kodio Modi Sidibé Nouhoum Coulibaly Alkaya Touré Djibril Sy Moustapha Tangara Saharé Fongoro 《临床诊断学期刊(英文)》 2020年第1期18-28,共11页
Introduction: Chronic renal failure (CKD) is defined as a glomerular filtration rate (GFR) of less than 60 ml/min/1.73m2 for more than 3 months [1]. Infectious complications are a major source of morbidity in patients... Introduction: Chronic renal failure (CKD) is defined as a glomerular filtration rate (GFR) of less than 60 ml/min/1.73m2 for more than 3 months [1]. Infectious complications are a major source of morbidity in patients with chronic renal failure. In Mali, we have no data on pneumopathies in this population, hence the interest of this study. The objective of this work was to determine the frequency of pneumopathies in patients with chronic renal failure, describe the clinical radio-types, identify the microorganisms involved, and assess the renal prognosis of pneumopathies. Materials and Methods: This was an 18-month prospective and descriptive study from January 1, 2018 to June 30, 2019 conducted in the nephrology and hemodialysis department of the University Hospital of Point G. Included were patients hospitalized during our study period with CKD associated with pneumopathy on a chest X-ray. Not included were all patients hospitalized outside the study period, all CKD cases without pneumonia, patients with incomplete records, and non-consenting patients. Results: We examined 1111 patients, 35 of whom presented an image on chest X-ray related to pneumopathy, a frequency of 3.15% of cases. Twenty-one men (60%) and 14 women (40%) with a sex ratio of 1.5. The mean age was 46.8 ± 13.9 years with extremes of 23 and 76 years. The types of pneumopathy on the chest X-ray were: alveolar pneumopathy: 23 cases (65.7%), pleuropneumopathy: 10 cases (28.6%) and cavitary pneumopathy: 2 cases (5.7%). Cytobacteriological sputum examination was positive in 65.7%;leukocytes (68.6% of cases). The germs found were: Klebsiella pneumoniae (25.7% of cases), Escherica coli (11.4%), Pseudomonas aeruginosa (5.7%), Staphylococcus aureus (5.7%), Citrobacter freundi (5.7%), Enterococus sp. (2.9%), Enterobacter cloacae (2.9%), Candida albicans (5.7%). The search for acid-alcohol-resistant bacilli (BAAR) in sputum was positive in 4 cases (11.4%). There was an association between the results of cytobacteriological examination of sputum and the r 展开更多
关键词 RENAL FAILURE DIALYSIS Pneumopathy MALI
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Erectile Dysfunction in Chronic Hemodialysis Patients at the University Hospital Center of Point-G in Mali 认领
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作者 Seydou Sy Magara Samaké +11 位作者 Hamadoun Yattara Moctar Coulibaly Ibrahima Koné Aboubacar Sidiki Fofana Djénèba Diallo Atabieme Kodio Modi Sidibé Nouhoum Coulibaly Alkaya Touré Djibril Sy Moustapha Tangara Saharé Fongoro 《临床诊断学期刊(英文)》 2020年第1期29-40,共12页
Introduction: Erectile Dysfunction (ED) is defined as the inability to achieve or maintain an erection sufficient for sexual intercourse. The frequency of erectile dysfunction in patients with kidney failure is estima... Introduction: Erectile Dysfunction (ED) is defined as the inability to achieve or maintain an erection sufficient for sexual intercourse. The frequency of erectile dysfunction in patients with kidney failure is estimated at 50% to 70%. The objective of this work was to determine the frequency of sexual dysfunction in chronic hemodialysis patients, to evaluate the psycho-social impact and to describe hormonal disturbances. Patients and Methods: This was a descriptive prospective study carried out from 3 April to 31 August 2017 in the nephrology and haemodialysis department of the Point G University Hospital. She has been interested in men over the age of 18 who have been on chronic hemodialysis for more than a year. Sexual dysfunction was assessed using the questionnaire: International Index of Erectile Function (IIEF-5). Results: Sixty-five patients were included. Forty-six (70.8%) had severe (30.8%), moderate (13.8%) and mild (26.2%) ED. 56.9% of patients had libido disorders, with decreased sexual desire (38.5%);absent sexual desire (18.5%). Sexual desire was normal in 43.1% of patients. Sexual activity was absent in 20 patients (30.8%). Sexual rigidity was reduced in 28 patients (43.1%) and normal in 24 patients (36.9%). The mean age of our patients was 42.55 years with a median age of 40 years and extremes of 23 and 74 years. Eighty percent were married. Nine patients (13.8%) were using sildenafil-based medications. Antihypertensives were prescribed in 93.9% and erythropoietin in 30.8% of patients. The main impact groups were anxiety (53.8%), fear of failure (27.7%), insomnia (7.7%) and anxiety (6.1%). And defence mechanisms included: understanding (54.7%);isolation (24.6%);repression (7.7%);quarrel (7.7%);and divorce in 1 case (1.5%). The occurrence of ED was related to hypotestosterolemia (p = 0.030), and between low libido and testosterone (p = 0.001). Nutritional status was satisfactory in 78.4% of our patients. Moderate and at and severe undernutrition was found in equal proportions (10.8%) in our patien 展开更多
关键词 Erectile DYSFUNCTION RENAL Failure DIALYSIS MALI
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基于光纤传感器的透析穿刺针头漏血检测方法研究 认领
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作者 张敏 邱召运 +3 位作者 陈雪梅 王倩倩 齐静 隋亚奇 《生物医学工程研究》 2020年第2期181-185,共5页
基于光导纤维设计了一种检测血红细胞浓度的光纤传感器,并将光纤传感器用于透析穿刺针头的漏血检测,提出了一种漏血检测的新方法。通过动物血样实验,分别测量了红、绿、蓝三色光为光源的光纤传感器的输出曲线,对比分析了三色光源的光纤... 基于光导纤维设计了一种检测血红细胞浓度的光纤传感器,并将光纤传感器用于透析穿刺针头的漏血检测,提出了一种漏血检测的新方法。通过动物血样实验,分别测量了红、绿、蓝三色光为光源的光纤传感器的输出曲线,对比分析了三色光源的光纤传感器的输出特性,证明蓝光源光纤传感器检测灵敏度最高;通过志愿者血样实验测量了蓝光源光纤传感器输出特性曲线,并确定了报警阈值范围。结果证明,以蓝光为光源的光纤传感器漏血检测方法具有灵敏度高和安全可靠的优点,能够准确检测透析穿刺针头的微漏血量。此种漏血检测报警装置能够在透析过程中对穿刺针头的微量漏血进行实时监测,避免透析中发生漏血事故。 展开更多
关键词 透析 漏血 穿刺针头 光纤传感器 灵敏度
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Acute Kidney Injury (AKI) in the Setting of Multi-Organ Dysfunction Syndrome (MODS) Secondary to Yellow Fever Infection (YFI) in a 19-Year-Old Woman 认领
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作者 Peter K. Uduagbamen Charles J. Elikwu +3 位作者 Adesola T. Oyelese Marion I. Ogunmola Tunde E. Thompson Tolulope E. Falana 《生物科学与医学(英文)》 2020年第9期142-148,共7页
<strong>Background: </strong>Outbreak of yellow fever infection (YFI), a mosquito-borne disease, occurs sporadically worldwide especially in tropical nations. Acute kidney injury (AKI) commonly results fro... <strong>Background: </strong>Outbreak of yellow fever infection (YFI), a mosquito-borne disease, occurs sporadically worldwide especially in tropical nations. Acute kidney injury (AKI) commonly results from YFI and could be associated with a poor prognosis for victims even under intensive care unit (ICU). Pathophysiologic mechanisms for AKI include hypovolemic shut down, cytotoxicity, acute tubular necrosis (ATN), hemolysis, or coagulopathy. Early diagnosis, prompt and effective treatment modalities including dialysis improve treatment outcome. <strong>Aim: </strong>We report the case management of a 19-year-old woman who had yellow fever infection complicated by acute kidney injury in the setting of multi-organ dysfunction syndrome (MODS). <strong>Case Presentation: </strong>A 19-year-old woman who presented with fever, headache and vomiting for 2 weeks. In the course of the illness, urine volume became reduced and coke colored, followed by body swelling, yellowness of the eyes bleeding from the orifices. Examination revealed an acutely ill looking woman, icteric, and with pedal edema. Her pulse was 100/min and blood pressure was 120/80 mmHg. Liver was enlarged, soft and tender. She had proteinuria 3+ and polymerase chain reaction (PCR) confirmed yellow fever infection. She had markedly deranged serum biochemical parameters for which she had a three-hour session of hemodialysis with Heparin anticoagulation. The urea reduction ratio (URR) was 46.9%. Barrier nursing was commenced. She had 7 units of whole blood and a pint of fresh frozen plasma (FFP) with antibiotics, Rabeprazole, Tranexamic acid, Vitamin K and Frusemide. She had the second dialysis session of HD and entered into the recovering phase of AKI and was subsequently discharged after 18th days on admission. <strong>Conclusion: </strong>Yellow fever infection occurs sporadically and could lead to MODS involving the kidneys, liver and hematologic system. Prompt initiation of dialysis, correction of coagulopathy, and antibiotics use are measures needed to 展开更多
关键词 Acute Kidney Injury Acute Tubular Necrosis DIALYSIS Yellow Fever Virus Fresh Frozen Plasma
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Parathyroidectomy in Chronic Haemodialysis in the Nephrology and Haemodialysis Department at the University Hospital Center of Point G in Bamako, Mali 认领
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作者 Saharé Fongoro Hamadoun Yattara +9 位作者 Seydou Sy Magara Samaké Djénèba Diallo Moctar Coulibaly Fatoumata Modjéré Doumbia Djibril Samaké Moustapha Tangara Alkaya Touré Atabième Kodio Nouhoum Coulibaly 《肾脏病(英文)》 2020年第2期135-143,共9页
<strong>Introduction:</strong> Secondary hyperparathyroidism is a common complication in chronic hemodialysis patients. It is characterized by hypersecretion of parathormone by the parathyroid glands to ma... <strong>Introduction:</strong> Secondary hyperparathyroidism is a common complication in chronic hemodialysis patients. It is characterized by hypersecretion of parathormone by the parathyroid glands to maintain phosphocalcium homeostasis in response to hypocalcemia, lowering of 1.25 dihydroxy vitamin D3 and hyperphosphatemia. <strong>Objective:</strong> To analyze the results of parathyroidectomy (PTX) in cases of secondary hyperparathyroidism (HPTS), report the post-operative course and early and late complications. Patients and Methods: We conducted a retrospective study of ten (10) patients with chronic renal failure operated on at the CHU of Point G over a 32-month period, from January 1, 2016 to August 31, 2019. We analyzed the clinical, biological, radiological and histological parameters of the thyroid glands. <strong>Results:</strong> We have collected 33 cases of secondary hyperparathyroidism. Ten (10) patients met the inclusion criteria. They were 45 years old on average, seven (7) women and three (3) men, in dialysis for an average of 6.8 years before parathyroidectomy. Half of the initial kidney disease was of vascular origin (HTA). No cases of diabetic nephropathy were identified. Symptoms were in order of frequency: bone pain (60%), paresthesia (50%), functional impotence of the lower limbs (50%). Radiological signs included demineralisation (5 out of 6 cases) and brown tumour associated with a fracture (1 out of 6 cases). The most frequent indication for parathyroidectomy (100%) was persistence despite treatment of a serum PTH concentration above 1000 pg/ml. Subtotal PTX (7/8) was performed after cervical ultrasound in all patients. Histological analysis of the parathyroid glands showed adenoma (60%) and hyperplasia in 40% of cases. The evolution was marked by a progressive reduction of the parathormone level over twelve (12) months, without achieving normalization. This could be related to sub-dialysis (generator failure with reduction of dialysis time). There were no cases of complications or mo 展开更多
关键词 Chronic Renal Failure Secondary Hyperparathyroidism DIALYSIS PARATHYROIDECTOMY
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Non-Infectious Complications of Peritoneal Dialysis in Senegal 认领
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作者 Ahmed Tall Lemrabott Maria Faye +12 位作者 Moustapha Faye Abdoul Hassane Sanlé Traoré Mouhamadou Moustapha Cissé Khodia Fall Yaya Kane Zeinabou Maiga Moussa Tondi Mansour Mbengue Bacary Ba Niakhalee Keita Seynabou Diagne Abdou Niang Boucar Diouf El Hadji Fary Ka 《肾脏病(英文)》 2020年第1期43-49,共7页
Introduction: Senegal has pioneered the implementation of peritoneal dialysis (PD) in West Africa, practicing it since 2004. Non-infectious complications are a significant cause of failure of this technique and the tr... Introduction: Senegal has pioneered the implementation of peritoneal dialysis (PD) in West Africa, practicing it since 2004. Non-infectious complications are a significant cause of failure of this technique and the transfer of patients to haemodialysis. The aim of this study was to determine the prevalence and the different types of non-infectious complications in our context. Patients and Methods: This was a 5-year, descriptive, retrospective study of patients on chronic peritoneal dialysis for more than 3 months. Results: During the study period, 75 patients were included. The prevalence of non-infectious complications was 88%, including 45.3% mechanical complications and 76% metabolic complications. Catheter migration was the most common mechanical complication (55.9%), followed by catheter blockage (23.5%). Metabolic complications were dominated by hypoalbuminemia (76.3%). Dyslipidaemia and hypokalaemia affected more than 50% of patients, occurring in 59.3% and 56.9% of cases, respectively. Conclusion: In our study, non-infectious complications related to PD were frequent and varied. They remain a significant cause of technical failure. Mechanical complications are often the cause of permanent transfer to haemodialysis. 展开更多
关键词 PERITONEAL DIALYSIS NON-INFECTIOUS COMPLICATIONS CATHETER Migration HYPOALBUMINEMIA Hypokalaemia
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A Cross-Cultural Investigation of the Lifestyle Factors Affecting Laypeople’s Allocation of a Scarce Medical Resource 认领
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作者 Agathe Nguyen Huynh Adrian Furnham Alastair McClelland 《健康(英文)》 2020年第2期141-157,共17页
This study investigates how lifestyle factors affect laypeople’s allocation of a scarce medical resource and explores cross-cultural differences in ethical decision-making between the UK, France and Switzerland. A to... This study investigates how lifestyle factors affect laypeople’s allocation of a scarce medical resource and explores cross-cultural differences in ethical decision-making between the UK, France and Switzerland. A total of 193 participants completed an online questionnaire in which they had to rate the profiles of 16 hypothetical patients in terms of priority for access to kidney dialysis. Each profile was a unique combination of the following lifestyle factors: smoking behaviour, alcohol consumption, weight and amount of physical activity. As predicted, it was found that non-smokers were favoured over smokers, moderate drinkers over heavy drinkers, normal weight patients over obese patients and frequent exercisers over infrequent exercisers. However, contrary to our predictions, no cross-cultural differences were evident. The potential impact of these findings with respect to the formulation of guidelines for allocating scarce medical resources is discussed. 展开更多
关键词 ALLOCATION Kidney DIALYSIS SMOKING Alcohol Weight ADDICTION
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单病种护理路径干预在维持性血液透析患者中的应用效果 认领
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作者 杨柳 赵琳娜 +1 位作者 武海捷 邵莉 《中华现代护理杂志》 2020年第30期4265-4269,共5页
目的:观察单病种护理路径干预在维持性血液透析(MHD)患者中的应用效果。方法:采用便利抽样法,选取2018年6月—2019年6月于首都医科大学附属北京友谊医院行MHD治疗的128例患者,采用随机数字表法分为单病种护理组和常规护理组,各64例。常... 目的:观察单病种护理路径干预在维持性血液透析(MHD)患者中的应用效果。方法:采用便利抽样法,选取2018年6月—2019年6月于首都医科大学附属北京友谊医院行MHD治疗的128例患者,采用随机数字表法分为单病种护理组和常规护理组,各64例。常规护理组给予常规MHD护理干预,单病种护理干预组在常规护理干预的基础上,基于临床护理路径,针对首次透析患者、透析间期患者、维持性透析期患者制订单病种护理路径进行护理干预。干预6个月后,比较两组患者对透析知识的掌握情况、并发症发生率及透析耐受度。结果:单病种护理组患者饮食原则、功能锻炼、用药原则、急慢性并发症、内瘘及静脉置管5个方面评分及透析知识总分均高于常规护理组;单病种护理组的渗血、血栓发生率及总体并发症发生率均低于常规护理组;单病种护理组患者的肾脏病为目标的评估、生活质量评估得分以及透析生活质量问卷总得分均高于常规护理组;差异均有统计学意义(P<0.05)。结论:单病种护理路径干预能够提高MHD患者透析知识掌握程度,降低并发症发生率,改善患者透析耐受度。 展开更多
关键词 透析 维持性血液透析 单病种 护理路径 并发症 透析耐受度
Comparison of clinical features and outcomes in peritoneal dialysisassociated peritonitis patients with and without diabetes:A multicenter retrospective cohort study 认领
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作者 Ling-Fei Meng Li-Ming Yang +7 位作者 Xue-Yan Zhu Xiao-Xuan Zhang Xin-Yang Li Jing Zhao Shi-Chen Liu Xiao-Hua Zhuang Ping Luo Wen-Peng Cui 《世界糖尿病杂志:英文版(电子版)》 SCIE CAS 2020年第10期435-446,共12页
BACKGROUND The number of end-stage renal disease patients with diabetes mellitus(DM)who are undergoing peritoneal dialysis is increasing.Peritoneal dialysis-associated peritonitis(PDAP)is a serious complication of per... BACKGROUND The number of end-stage renal disease patients with diabetes mellitus(DM)who are undergoing peritoneal dialysis is increasing.Peritoneal dialysis-associated peritonitis(PDAP)is a serious complication of peritoneal dialysis leading to technical failure and increased mortality in patients undergoing peritoneal dialysis.The profile of clinical symptoms,distribution of pathogenic organisms,and response of PDAP to medical management in the subset of end-stage renal disease patients with DM have not been reported previously.Discrepant results have been found in long-term prognostic outcomes of PDAP in patients with DM.We inferred that DM is associated with bad outcomes in PDAP patients.AIM To compare the clinical features and outcomes of PDAP between patients with DM and those without.METHODS In this multicenter retrospective cohort study,we enrolled patients who had at least one episode of PDAP during the study period.The patients were followed for a median of 31.1 mo.They were divided into a DM group and a non-DM group.Clinical features,therapeutic outcomes,and long-term prognostic outcomes were compared between the two groups.Risk factors associated with therapeutic outcomes of PDAP were analyzed using multivariable logistic regression.A Cox proportional hazards model was constructed to examine the influence of DM on patient survival and incidence of technical failure.RESULTS Overall,373 episodes occurred in the DM group(n=214)and 692 episodes occurred in the non-DM group(n=395).The rates of abdominal pain and fever were similar in the two groups(P>0.05).The DM group had more infections with coagulase-negative Staphylococcus and less infections with Escherichia coli(E.coli)as compared to the non-DM group(P<0.05).Multivariate logistic regression analysis revealed no association between the presence of diabetes and rates of complete cure,catheter removal,PDAP-related death,or relapse of PDAP(P>0.05).Patients in the DM group were older and had a higher burden of cardiovascular disease,with lower level of ser 展开更多
关键词 Diabetes mellitus MORTALITY Peritoneal dialysis Peritoneal dialysis-associated peritonitis Technical failure
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前臂透析通路狭窄介入治疗穿刺点的意义探讨 认领
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作者 陈寒 刘杨东 《中国继续医学教育》 2020年第1期98-100,共3页
慢性肾功能不全晚期即为尿毒症,对于尿毒症患者开展透析治疗属于维持患者生命的主要措施,所以临床中将透析通路比作生命通路,透析治疗期间由于血管反复穿刺,或是穿刺方法不当,会引发血管内膜产生增生,血管管腔出现闭塞,严重者会导致血... 慢性肾功能不全晚期即为尿毒症,对于尿毒症患者开展透析治疗属于维持患者生命的主要措施,所以临床中将透析通路比作生命通路,透析治疗期间由于血管反复穿刺,或是穿刺方法不当,会引发血管内膜产生增生,血管管腔出现闭塞,严重者会导致血管内部出现血栓,最终造成无法满足透析要求,对此临床中一般应用手术治疗或是内科药物治疗维修透析通路。DSA引导下开展球囊扩张术属于现在临床中十分多见的治疗措施,虽然无法根治或是永久解决通路狭窄现象,但是到目前为止没有根治永久解决透析通路的措施,开展介入治疗期间,通过不同穿刺入路开通成功率存在显著差异,怎样选取穿刺点,使透析通路狭窄开通成功率获得提升是现在临床专家急需解决的问题。 展开更多
关键词 介入治疗 穿刺点 透析治疗 前臂透析通路狭窄 开通成功率 应用价值
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文章速递四通胶囊防治动静脉内瘘血栓形成的临床研究 认领
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作者 马营 申凤云 +3 位作者 肖娟 姚美 陈梅 曹海珍 《大医生》 2020年第13期35-37,共3页
目的探讨四通胶囊防治动静脉内瘘(AVF)血栓形成的临床效果。方法选取2018年1月至2019年4月泰安市中医二院收治的150例采取维持性血液透析患者为研究对象,根据随机数字表法分为A、B、C组,各50例。A组进行四通胶囊治疗,B组进行低分子肝素... 目的探讨四通胶囊防治动静脉内瘘(AVF)血栓形成的临床效果。方法选取2018年1月至2019年4月泰安市中医二院收治的150例采取维持性血液透析患者为研究对象,根据随机数字表法分为A、B、C组,各50例。A组进行四通胶囊治疗,B组进行低分子肝素钠治疗,C组不使用药物治疗。观察AVF术后通畅状况、内瘘成熟时间、动静脉内瘘血流量(AVFB);对三组凝血酶原时间(PT)、凝血酶时间(TT)、血浆纤维蛋白原(FIB)、活化部分凝血酶原时间(APTT)进行检测。结果A组内瘘成熟时间显著短于B、C组,B组内瘘成熟时间显著短于C组;A组内瘘通畅率和AVFB显著高于B、C组,差异有统计学意义(P<0.05),B组内瘘通畅率和AVFB显著高于C组,差异有统计学意义(P<0.05)。治疗后,A组TT、PT、APTT显著高于B、C组,B组TT、PT、APTT显著高于C组,A组FIB显著低于B、C组(P<0.05),B组FIB显著低于C组(P<0.05)。结论糖尿病透析患者采取四通胶囊能够有效防止AVF内血栓形成,可对患者透析治疗有效保障。 展开更多
关键词 四通胶囊 动静脉内瘘 血栓形成 肾功能衰竭 透析
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文章速递宁波市鄞州区透析患者30天再入院影响因素分析及简易评分工具构建 认领
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作者 孙小宇 聂振禹 +3 位作者 孙烨祥 包蓓艳 林鸿波 张路霞 《中国血液净化》 CSCD 2020年第11期721-725,共5页
目的30天再入院是反映疾病转归和医疗质量的重要指标。本研究通过分析宁波市鄞州区健康医疗大数据平台数据,探讨透析患者发生30天再入院的影响因素、估算效应大小并建立简易评分工具。方法纳入2010年1月~2020年1月在鄞州区医疗机构进行... 目的30天再入院是反映疾病转归和医疗质量的重要指标。本研究通过分析宁波市鄞州区健康医疗大数据平台数据,探讨透析患者发生30天再入院的影响因素、估算效应大小并建立简易评分工具。方法纳入2010年1月~2020年1月在鄞州区医疗机构进行过住院治疗,未发生院内死亡且出院诊断ICD编码符合透析相关诊断的18岁以上患者。采集患者年龄,性别,住院记录,出院诊断等信息。对于有多次住院记录的患者,随机选择一次作为指示住院记录。统计模型采用COX比例风险模型。结果最终纳入患者1614例,发生30天再入院患者348例(21.56%)。构建多因素COX比例风险模型显示,与患者30天再入院相关的因素为高查尔斯合并症指数(Charles comorbidity index,CCI)评分(对比CCI 2分组,3~4分组风险比HR=1.257,95%CI:0.917~1.724,≥5分组HR=1.848,95%CI:1.374~2.486)、既往半年内住院次数(HR=1.576,95%CI:1.471~1.688)、本次住院时间(HR=1.010,95%CI:1.001~1.020)、腹膜透析(对比血液透析,HR=1.505,95%CI:1.207~1.876)。利用以上因素构建简易评分工具,可通过患者评分对应再入院发生概率。结论对宁波市鄞州区住院透析患者的分析显示,高CCI评分、既往半年内住院次数多、住院时间长、腹膜透析患者发生30天再入院的风险更高,应用简易评分工具可用于临床中对透析患者再入院风险进行评估。 展开更多
关键词 30天再入院 透析 CCI评分 电子医疗记录 风险预测
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文章速递连续性血液净化治疗在危重患者急性左心衰抢救中的护理观察 认领
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作者 徐莉 《智慧健康》 2020年第24期32-33,共2页
目的探究护理干预在连续性血液净化治疗危重患者急性左心衰抢救中的效果。方法选取2019年1月至2020年1月本院收治的48例急性左心衰危重患者为研究对象,通过数字列表法分为对照组24例行常规护理,研究组24例行系统化护理干预,比较两组抢... 目的探究护理干预在连续性血液净化治疗危重患者急性左心衰抢救中的效果。方法选取2019年1月至2020年1月本院收治的48例急性左心衰危重患者为研究对象,通过数字列表法分为对照组24例行常规护理,研究组24例行系统化护理干预,比较两组抢救及护理效果。结果抢救有效率研究组为100%、高于对照组的83.33%,护理满意度研究组为95.83%、高于对照组的75%,差异均有统计学意义(P<0.05)。结论在急性左心衰危重患者连续性血液净化治疗中系统化护理干预效果显著,值得推广应用。 展开更多
关键词 连续性血液净化治疗 急性左心衰 护理干预 透析
文章速递外周血T细胞亚群在慢性肾脏病透析患者中的表达与出现肺动脉高压的相关性 认领
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作者 童艳 张泉 +3 位作者 邵亚 余芬 叶巍 杨楷 《临床和实验医学杂志》 2020年第21期2306-2309,共4页
目的研究外周血T细胞亚群在慢性肾脏病(CKD)透析患者中的表达与出现肺动脉高压(PAH)的相关性。方法前瞻性选择2017年6月至2018年8月湖北省中西医结合医院收治的CKD透析患者127例作为研究对象,根据美国超声心动图协会右心功能评估指南分... 目的研究外周血T细胞亚群在慢性肾脏病(CKD)透析患者中的表达与出现肺动脉高压(PAH)的相关性。方法前瞻性选择2017年6月至2018年8月湖北省中西医结合医院收治的CKD透析患者127例作为研究对象,根据美国超声心动图协会右心功能评估指南分为PAH组53例,非PAH组74例。观察比较2组患者T细胞亚群(CD3+、CD4+、CD3+CD8+、CD8+、CD8+CD69+)和血液生化指标[尿素氮(BUN)、血红蛋白浓度(Hb)、钙离子(Ca2+)、肌酐(Scr)、甲状旁腺激素(PTH)、血浆脑钠肽(BNP)],并对CKD透析患者出现PAH的相关因素分析及多因素Logistic回归分析。结果PAH组CD8+、CD8+CD69+值明显低于非PAH组,差异具有统计学意义(P<0.05);CD3+、CD4+、CD3+CD8+值比较差异无统计学意义(P>0.05);PAH组BUN、Hb、Scr、Ln(BNP)值明显高于非PAH组,差异具有统计学意义(P<0.05);2组Ca2+、PTH值比较差异无统计学意义(P>0.05);PAH组CKD透析患者PASP与CD8+、CD8+CD69+、BUN、Scr、Ln(BNP)呈正相关(P<0.05),与Hb呈负相关(P<0.05);CD8+、CD8+CD69+、Hb及Ln(BNP)水平CKD透析患者出现PAH的独立危险因素(P<0.05)。结论CKD透析患者外周血CD8+T细胞、CD8+CD69+T细胞表达异常及血液Hb、BNP指标超出正常范围是导致CKD透析患者出现PAH的独立危险因素。 展开更多
关键词 慢性肾脏病 透析 外周血T细胞亚群 肺动脉高压 相关性
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文章速递补中益气汤治疗血液透析并慢性低血压患者的效果 认领
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作者 金一峰 《中国医药指南》 2020年第29期143-144,共2页
目的分析补中益气汤用于治疗血液透析合并慢性低血压患者的临床价值。方法选取2017年10月至2019年10月沈阳市中医院收治的126例血液透析合并慢性低血压患者作为观察对象,根据随机数字表法将患者分为对照组(63例)和试验组(63例)。对照组... 目的分析补中益气汤用于治疗血液透析合并慢性低血压患者的临床价值。方法选取2017年10月至2019年10月沈阳市中医院收治的126例血液透析合并慢性低血压患者作为观察对象,根据随机数字表法将患者分为对照组(63例)和试验组(63例)。对照组给予常规西药治疗,试验组在对照组用药基础上增加补中益气汤治疗,比较两组患者的血压改善情况、整体恢复情况、不良反应发生情况及预后满意度。结果治疗后,试验组慢性低血压症状明显较对照组改善,治疗总有效率、患者及其家属对预后的满意度高于对照组,差异有统计学意义(P<0.05)。两组仅少数患者在用药后出现了消化道不良反应,但经过对症支持处理后症状均消失,且两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论将补中益气汤用于治疗血液透析合并慢性低血压患者的效果突出,能够显著改善患者的临床症状,促进患者的身体恢复,具有较高的临床应用价值。 展开更多
关键词 透析疗法 慢性低血压 补中益气汤 不良反应 满意度
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猪胰脏中胰淀粉酶的提取及其稳定性 认领
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作者 岳晓禹 陈贵敏 《食品工业》 CAS 北大核心 2020年第2期46-50,共5页
研究胰淀粉酶的最佳提取条件和胰淀粉酶的稳定性保存。以冷冻猪胰脏为原料提取胰淀粉酶酶,以酶活力为衡量指标,在单因素试验基础上通过正交试验来探究提取胰淀粉酶的最佳条件,通过透析对粗胰淀粉酶液进行浓缩,探究胰淀粉酶液的保存。胰... 研究胰淀粉酶的最佳提取条件和胰淀粉酶的稳定性保存。以冷冻猪胰脏为原料提取胰淀粉酶酶,以酶活力为衡量指标,在单因素试验基础上通过正交试验来探究提取胰淀粉酶的最佳条件,通过透析对粗胰淀粉酶液进行浓缩,探究胰淀粉酶液的保存。胰淀粉酶最佳提取条件为:提取剂采用磷酸盐缓冲液、提取pH 6.8、提取时间2 h、提取温度30℃,透析之后酶活达2 614.66 U/g,是提取剂提取酶的5.2倍,胰淀粉酶保存温度越低胰淀粉酶的酶活力保存时间越长,且胰淀粉酶酶活力下降速度越慢。该方法简单易操作,提取工艺时间短,成本低,利于环保、易于产业化生产。 展开更多
关键词 胰淀粉酶 酶活力 提取剂 透析 稳定性
继发性甲状旁腺功能亢进症术后迟发性出血的原因分析 认领
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作者 冯剑平 唐诗彬 +1 位作者 叶剑 谭健辉 《中国基层医药》 CAS 2020年第15期1828-1831,共4页
目的探讨继发性甲状旁腺功能亢进症术后迟发性出血的原因及处理措施。方法回顾性分析南方医科大学顺德医院甲状腺外科2014年11月至2018年11月手术治疗的继发性甲状旁腺功能亢进症患者56例的临床资料,对其中5例术后迟发性出血的患者进行... 目的探讨继发性甲状旁腺功能亢进症术后迟发性出血的原因及处理措施。方法回顾性分析南方医科大学顺德医院甲状腺外科2014年11月至2018年11月手术治疗的继发性甲状旁腺功能亢进症患者56例的临床资料,对其中5例术后迟发性出血的患者进行原因分析。结果5例术后出血患者均为终末期肾病血液透析患者(5/56,8.93%),其中颈前静脉出血1例,甲状腺断面渗血1例,舌骨下肌群渗血3例,环甲肌渗血1例,所有病例经及时处理止血后,伤口甲级愈合,无死亡病例。结论继发性甲状旁腺术后出血发生率不低,做好围手术期预防措施,早期明确诊断及处理,能减少其并发症及危害。 展开更多
关键词 甲状旁腺功能亢进症 继发性 肾病 透析 甲状旁腺切除术 手术后出血
水溶性姜黄素制备工艺的研究 认领
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作者 周代营 丁立 +3 位作者 曾庆珊 卢俊囧 李灶莲 林修良 《山东化工》 CAS 2020年第17期29-30,共2页
本研究通过采用表面活性剂乳化与两亲性共聚物自组装并在蒸馏水中透析。采用透析法制备姜黄素两亲性共聚物纳米胶束,通过正交试验考察姜黄素溶解度。与传统的技术相比,该技术具有工艺简单,投资设备低,产品稳定等特点。并用紫外光谱的方... 本研究通过采用表面活性剂乳化与两亲性共聚物自组装并在蒸馏水中透析。采用透析法制备姜黄素两亲性共聚物纳米胶束,通过正交试验考察姜黄素溶解度。与传统的技术相比,该技术具有工艺简单,投资设备低,产品稳定等特点。并用紫外光谱的方法加以鉴定,按照本研究生产的姜黄素溶解度得到了提高。 展开更多
关键词 姜黄素 两亲性共聚物 透析
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糖尿病肾病透析过程中低血糖反应的预见性护理及营养干预 认领
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作者 魏军 李霞 《糖尿病新世界》 2020年第19期179-181,共3页
目的观察预见性护理及营养干预对糖尿病肾病透析过程中低血糖反应的干预效果。方法将2016年6月—2019年5月该科行维持性血液透析的糖尿病肾病患者170例,随机分为对照组和观察组,各85例,两组患者均采用无糖碳酸氢盐进行透析。对照组采用... 目的观察预见性护理及营养干预对糖尿病肾病透析过程中低血糖反应的干预效果。方法将2016年6月—2019年5月该科行维持性血液透析的糖尿病肾病患者170例,随机分为对照组和观察组,各85例,两组患者均采用无糖碳酸氢盐进行透析。对照组采用常规护理,观察组针对透析过程中低血糖反应的相关诱因采用预见性护理和营养干预。检测两组透析时发生低血糖的比率,并统计两组患者针对护理打分满意度。结果观察组低血糖发生率(1.2%)低于对照组(17.6%),差异有统计学意义(χ^2=13.523,P<0.05)。观察组患者对护理的满意度(98.8%)高于对照组(85.9%),差异有统计学意义(χ^2=10.078,P<0.05)。结论对糖尿病肾病透析患者采取低血糖反应的预见性护理及营养干预措施,可降低患者低血糖的发生,提高患者的护理满意度,有效改善患者的透析质量和生活质量。 展开更多
关键词 糖尿病肾病 透析 低血糖反应 预见性 营养干预
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个体化延续护理对透析患者下肢深静脉血栓形成的预防效果及自我管理能力影响 认领
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作者 温丽新 《国际感染病学(电子版)》 CAS 2020年第1期173-174,共2页
目的 研究个体化延续护理对透析患者下肢深静脉血栓形成的预防效果及自我管理能力影响。方法 选取2016年11月-2017年11月在本院进行透析的患者116例,按数字表法将患者的均分为对照组(常规护理)、研究组(个体化延续护理),对患者的预防血... 目的 研究个体化延续护理对透析患者下肢深静脉血栓形成的预防效果及自我管理能力影响。方法 选取2016年11月-2017年11月在本院进行透析的患者116例,按数字表法将患者的均分为对照组(常规护理)、研究组(个体化延续护理),对患者的预防血栓知识的了解程度和自我管理能力进行评价。结果 研究组对于血栓产生原因、预防方法等方面知识的把握程度均明显高于对照组(P<0.05);研究组整体的自我管理能力显著高于对照组(P<0.05)。结论 在预防透析患者形成下肢深静脉血栓的过程中,对患者应用个体化延续护理可以提高患者对血栓相关知识的了解程度,有效预防血栓形成,还可以加强患者的自我管理,有助于患者疾病的治疗,可以在临床上应用。 展开更多
关键词 个体化延续护理 透析 下肢深静脉血栓 预防效果 自我管理能力
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