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Guided Care管理模型干预对老年慢性病管理的影响 认领
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作者 庄路 《中国继续医学教育》 2021年第2期126-130,共5页
目的探究基于Guided Care管理模型干预应用于老年患者中对药物不良反应风险的影响。方法选取医院2018年2月—2019年2月收治的老年患者106例,采用随机数字表法分为观察组和对照组,各53例。对照组实施常规干预,观察组实施基于Guided Care... 目的探究基于Guided Care管理模型干预应用于老年患者中对药物不良反应风险的影响。方法选取医院2018年2月—2019年2月收治的老年患者106例,采用随机数字表法分为观察组和对照组,各53例。对照组实施常规干预,观察组实施基于Guided Care管理模型干预。对比两组日常生活能力、家庭功能及社会支持水平。结果观察组干预后ADL评分高于对照组,差异有统计学意义(P<0.05)。观察组干预后APGAR评分高于对照组,差异有统计学意义(P<0.05)。观察组干预后SSRS评分高于对照组,差异有统计学意义(P<0.05)。结论对老年慢性病患者实施基于Guided Care管理模型干预可显著提升日常生活能力,强化家庭功能及社会支持。 展开更多
关键词 Guided Care管理模型 老年 药物不良反应 疾病管理 风险 防控
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SAR image de-noising via grouping-based PCA and guided filter 认领
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作者 FANG Jing HU Shaohai MA Xiaole 《系统工程与电子技术:英文版》 SCIE EI 2021年第1期81-91,共11页
A novel synthetic aperture radar(SAR)image de-noising method based on the local pixel grouping(LPG)principal component analysis(PCA)and guided filter is proposed.This method contains two steps.In the first step,we pro... A novel synthetic aperture radar(SAR)image de-noising method based on the local pixel grouping(LPG)principal component analysis(PCA)and guided filter is proposed.This method contains two steps.In the first step,we process the noisy image by coarse filters,which can suppress the speckle effectively.The original SAR image is transformed into the additive noise model by logarithmic transform with deviation correction.Then,we use the pixel and its nearest neighbors as a vector to select training samples from the local window by LPG based on the block similar matching.The LPG method ensures that only the similar sample patches are used in the local statistical calculation of PCA transform estimation,so that the local features of the image can be well preserved after coefficients shrinkage in the PCA domain.In the second step,we do the guided filtering which can effectively eliminate small artifacts left over from the coarse filtering.Experimental results of simulated and real SAR images show that the proposed method outstrips the state-of-the-art image de-noising methods in the peak signalto-noise ratio(PSNR),the structural similarity(SSIM)index and the equivalent number of looks(ENLs),and is of perceived image quality. 展开更多
关键词 synthetic aperture radar(SAR)image de-noising local pixel grouping(LPG) principal component analysis(PCA) guided filter
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Immediate implant placement in combination with platelet rich-fibrin into extraction sites with periapical infection in the esthetic zone:A case report and review of literature 认领
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作者 Jiao Fang Xi-Rui Xin +3 位作者 Wen Li Han-Chi Wang Hui-Xin Lv Yan-Min Zhou 《世界临床病例杂志》 SCIE 2021年第4期960-969,共10页
BACKGROUND In this case,platelet-rich fibrin(PRF)was added to guided tissue regeneration as a biomaterial in proper order for immediate planting in aesthetic area with periapical infection.CASE SUMMARY With the histor... BACKGROUND In this case,platelet-rich fibrin(PRF)was added to guided tissue regeneration as a biomaterial in proper order for immediate planting in aesthetic area with periapical infection.CASE SUMMARY With the history of endodontic failure in maxillary central incisor,a 34-year-old female patient required the extraction of maxillary anterior residual root and immediate implantation.Cone beam computed tomography and clinical observation were used to assess the regeneration of soft and bone tissue.Before operation,cone beam computed tomography showed the anterior residual root had serious periapical periodontitis with insufficient labial bone in the aesthetic zone.The patient underwent immediate implant placement and reconstruction of the bone substitution by modified guided bone regeneration.The barrier was a three-layer structure of PRF-collagen membrane-PRF that covered the mixture of PRF and Bio-Oss to promote both osteogenesis and soft tissue healing.At 6 mo postoperatively,the definitive crown was placed after accomplished finial impression.One-year follow-up showed a satisfactory aesthetic effect with no obvious absorption of the labial bone and soft tissue.CONCLUSION The use of PRF in combination with guided bone regeneration can serve as a reliable and simple adjuvant for immediate implanting in infected socket and result in a stable osteogenic effect with good aesthetic outcome. 展开更多
关键词 Immediate implant Platelet rich-fibrin Periapical infection Esthetic zone Guided bone regeneration Case report
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文章速递Multi-objective optimization of feature selection using hybrid cat swarm optimization 认领
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作者 GAO Xiao-Zhi NALLURI Madhu Sudana Rao +1 位作者 KANNAN K SINHAROY Diptendu 《中国科学:技术科学英文版》 SCIE EI CAS CSCD 2021年第3期508-520,共13页
With the pervasive generation of information from a wide range of sensors and devices,there always exist a large number of input features in databases,thus complicating machine learning problem formulation.However,cer... With the pervasive generation of information from a wide range of sensors and devices,there always exist a large number of input features in databases,thus complicating machine learning problem formulation.However,certain features are relatively impertinent to specific problems,which may degrade the performances of classifiers in terms of prediction accuracy,sensitivity,specificity,and recall rate.The main goal of a multi-objective optimization problem is to identify the subsets of the given features.To this end,a hybrid cat swarm optimization(HCSO)algorithm is proposed in our paper for performance improvement of the basic cat swarm optimization(CSO)that incorporates guided and competitive&inherent characteristics into the original CSO.The performance of HCSO has been tested by finding the optimal feature subset for 15 benchmark datasets.The number of class labels for these datasets varies between 2 and 40.The time complexity analysis of both CSO and HCSO has also been evaluated.Moreover,the performance of the proposed algorithm has been compared with that of simple CSO and other state-ofthe-art techniques.The performances obtained by HCSO have an average 2.68%improvement with a standard deviation of 2.91.The maximum performance improvement is up to 10.09%in prediction accuracy.Tested on the same datasets,CSO has yielded improvements within the range of-7.27%to 8.51%with an average improvement 0.9%and standard deviation 3.96.The statistical tests carried out in the experiments prove that HCSO manifests a moderately better feature selection capacity than that of its counterparts. 展开更多
关键词 feature selection competition cat swarm optimization guided search parameter evolution
文章速递Tunable dual-band terahertz graphene absorber with guided mode resonances 认领
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作者 吴俊 刘夏吟 黄喆 《中国物理B:英文版》 SCIE EI CAS CSCD 2021年第1期234-238,共5页
A tunable dual-band terahertz absorber is designed and investigated. The unit cell of the proposed absorber consists of a graphene monolayer on a guided-mode resonant filter. The graphene absorber presents > 40% ab... A tunable dual-band terahertz absorber is designed and investigated. The unit cell of the proposed absorber consists of a graphene monolayer on a guided-mode resonant filter. The graphene absorber presents > 40% absorption at two resonance frequencies, which is attributed to the guided mode resonances with different mode numbers. The electric field intensity distribution is analyzed to disclose the physical mechanism of such a dual-band absorption effect. Furthermore,the influence of optical properties of graphene, including Fermi level and relaxation time, on the absorption spectra are investigated. Finally, the influence of geometric parameters on the absorption spectrum is studied, which will provide useful guidance for the fabrication of this absorber. We believe that the results may be useful for developing the next-generation graphene-based optoelectronic devices. 展开更多
关键词 dual-band graphene guided mode resonance spectrum selective absorption
The Therapeutic Role of Guided Mental Imagery in Treating Stress and Insomnia: A Neuropsychological Perspective 认领
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作者 Ravinder Jerath Connor Beveridge +1 位作者 Michael Jensen Ruchir Paladiya 《医学心理学(英文)》 2020年第1期21-39,共19页
Excessive distress and insomnia are much too common in the modern world and often lead to a myriad of detrimental effects including loss of cognitive ability and even physical ailments such as cancer. Current pharmace... Excessive distress and insomnia are much too common in the modern world and often lead to a myriad of detrimental effects including loss of cognitive ability and even physical ailments such as cancer. Current pharmaceutical treatments can be addictive, detrimental to health, and in the case of insomnia don’t produce naturalistic sleep. We present a viewpoint on a potential adjunctive treatment of distress and insomnia that harnesses specific mental imagery as a component of mind/body relaxation technique. Via our perspective on the modern nature of stress and insomnia, our theoretical perspective on how specific guided mental imagery can be used to treat these ailments, and our review on the current literature on treatment with mental imagery, we hope to stimulate further research into mental health treatment with mental imagery which has traditionally been neglected. This perspective on the pathology of insomnia and distress is founded in prevailing “dysevolution” and hyper-arousal theories. Hyper-arousal is characterized in part by a vicious cycle of chronic physiological and emotional stimulation/distress. We argue for spatially based mental imagery in the form of nighttime-sky imagery to attenuate such pathology by breaking one away from a vicious cycle of stimulation and distress and discuss neuropsychological bases for its potential treatment mechanisms which include the autonomic nervous system and a phenomenal foundation of conscious cognition. 展开更多
关键词 MENTAL IMAGERY GUIDED IMAGERY INSOMNIA Chronic STRESS HYPERAROUSAL Vicious Cycle
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Resonant Characteristics in Sandwich Gratings 认领
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作者 Xuehui Xiong 《应用数学与应用物理(英文)》 2020年第12期3070-3074,共5页
In this paper, the intensity distributions of the magnetic field in the proposed sandwich grating were studied. The results indicated that there were two apparent enhanced transmission peaks. The magnetic intensity di... In this paper, the intensity distributions of the magnetic field in the proposed sandwich grating were studied. The results indicated that there were two apparent enhanced transmission peaks. The magnetic intensity distributions of these two peaks manifest that the narrow higher transmission enhancement peak was caused by guided mode resonance and the other wide low one was formed by surface plasmon resonance. The resonant wavelength was estimated by the momentum matching conditions of resonance. 展开更多
关键词 Sandwich Grating Guided Mode Resonance Surface Plasmon Resonance
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The Relationship between Implant Size and Success Rate in Computer Guided Implant Surgery 认领
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作者 Mohammed Abu Younis Raéd O. Abu Hantash 《生物医学工程(英文)》 2020年第12期267-274,共8页
Guided implant surgery gained acceptance and credit in implant dentistry. The aim of this study is to find out and evaluate the relationship between implant size and success rate following computed tomography scan gui... Guided implant surgery gained acceptance and credit in implant dentistry. The aim of this study is to find out and evaluate the relationship between implant size and success rate following computed tomography scan guided implant surgery. Sixty-four (36 females, 28 males) completely and partially edentulous patients aged between 42 and 65 years old were participated and fulfilled the inclusion criteria of the study. Two hundred and seventeen dental implants <u>(length: 10, 11.5, and 13 mm;Diameter: 3.3, 3.75, and 4.2 mm)</u> were placed using computed tomography scan guided implant surgery, 117 implants were placed in the maxilla, while 100 implants were placed in the mandible. The implants were evaluated for clinical parameters at 2, 4, and 12 weeks intervals after installation. <u>The overall success rate was 95.4%.</u> Clinical stability of the implant size (Diameter 3.3 mm, Length 10 mm) was the least as compared to other dimensions (<em>P</em> ≤ 0.05). Medium and large size implants (Diameter 3.75 and 4.2 mm, Length 11.5 and 13 mm) were the highest success rate in implant surgery. Implants width (diameter 3.3 mm) and length (10 mm) are best avoided in guided computed tomography surgery as compared with other implant sizes especially in atrophic bony areas. Computer-guided implant surgery remains exciting. Watchful planning and precise stability of the surgical guide are mandatory for successful protocol. Further investigations should be performed to assess such technique among dental patients from satisfactory point of view. Intensive cooperation between dentists and software engineering discipline should be aimed to maximize the success of such technique. 展开更多
关键词 Guided Surgery Surgical Template ACCURACY Implants Dimension
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基于视觉导航仓储AGV的模糊PID控制 认领
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作者 周阔海 黄民 +1 位作者 高宏 郎需强 《北京信息科技大学学报:自然科学版》 2020年第4期69-74,共6页
研究了仓储自动导引运输车(automatic guided vehicle,AGV)运动过程中由于随机非线性误差引起的AGV行走左右位置偏差问题。以建立AGV底盘相对应的运动学模型为基础,在仓储AGV运动控制中采用了模糊PID方法,依靠视觉传感器反馈的偏移误差... 研究了仓储自动导引运输车(automatic guided vehicle,AGV)运动过程中由于随机非线性误差引起的AGV行走左右位置偏差问题。以建立AGV底盘相对应的运动学模型为基础,在仓储AGV运动控制中采用了模糊PID方法,依靠视觉传感器反馈的偏移误差和偏移误差变化率,通过仓储AGV的合成速度进行运动调节。通过仿真实验发现在AGV运动控制中应用模糊PID控制方法较传统PID控制方法的结果曲线误差小。经测试,在视觉导航仓储AGV中运用模糊PID控制方法较传统PID控制方法的工作效率提高了5%。 展开更多
关键词 视觉导航 AGV(automatic guided vehicle) 模糊控制 PID
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Evaluation of axis alignment and refractive results of toric phakic IOL using image-guided system 认领
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作者 Sherif Emerah 《国际眼科杂志:英文版》 SCIE CAS 2020年第4期667-670,共4页
AIM: To evaluate accuracy of axis alignment and refractive results of toric phakic intraocular lens(IOL) implantation using a digital imaging system. METHODS: This retrospective study investigated toric implantable co... AIM: To evaluate accuracy of axis alignment and refractive results of toric phakic intraocular lens(IOL) implantation using a digital imaging system. METHODS: This retrospective study investigated toric implantable collamer lens(ICL) implantation in 30 eyes of 21 patients with myopic astigmatism more than 2.0 D guided with digital imaging system. Data were collected during the first week after phakic IOL implantation.RESULTS: Thirty eyes of 21 patients were included in our study. Patients includes 9 males and 12 females. The mean age of the patients was 26.5±7.1(range 21-44)y. The mean preoperative manifest astigmatism was 3.2±1.7(range from 2.25 to 4.75) D. The mean postoperative uncorrected distance visual acuity(UCDVA) were 0.07±0.07(range from 0.1 to 0.0) log MAR. The mean postoperative residual refractive cylinder was 0.25±0.29(range 0-0.75) D. Eyes with postoperative residual refractive cylinder of 0.5 D or less represented 80%(24 eyes). The mean postoperative toric IOL misalignment measured by the OPD scan III was 1.9°±1.45°(range from 0 to 5°). CONCLUSION: Image guided system allows accurate alignment of toric ICL. This is associated with good postoperative visual acuity and low residual refractive astigmatism which correlates with the precision of toric phakic IOL alignment. 展开更多
关键词 myopic ASTIGMATISM TORIC INTRAOCULAR lenses image guided SYSTEM
Guided Care护理模式对老年慢性心力衰竭患者家庭功能的影响 认领
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作者 彭小荷 《首都食品与医药》 2020年第19期135-136,共2页
目的分析Guided Care护理模式对老年慢性心力衰竭患者家庭功能的影响.方法选取我院2017年2月~2019年5月老年慢性心力衰竭患者87例,2017年2月~2018年3月41例为对照组,接受常规护理干预;2018年4月~2019年5月46例为观察组,在对照组基础上接... 目的分析Guided Care护理模式对老年慢性心力衰竭患者家庭功能的影响.方法选取我院2017年2月~2019年5月老年慢性心力衰竭患者87例,2017年2月~2018年3月41例为对照组,接受常规护理干预;2018年4月~2019年5月46例为观察组,在对照组基础上接受Guided Care护理模式干预,比较两组干预前后家庭功能(家庭关怀度指数量表)、护理满意度.结果干预后,观察组家庭关怀度指数量表评分较对照组高(P<0.05);观察组护理满意度较对照组高(P<0.05).结论老年慢性心力衰竭患者接受Guided Care护理模式干预,能提高家庭关怀度程度,且护理满意度高. 展开更多
关键词 Guided Care护理模式 慢性心力衰竭 生活质量
Efficacy of concentrated growth factors combined with mineralized collagen on quality of life and bone reconstruction of guided bone regeneration 认领
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作者 Yan Dai Xiao-Hui Han +3 位作者 Li-Hua Hu Hai-Wei Wu Sheng-Yun Huang Yu-Peng Lu 《再生生物材料(英文版)》 SCIE 2020年第3期313-320,共8页
To evaluate the clinical efficacy of concentrated growth factors(CGFs)combined with mineralized collagen(MC)in guided bone regeneration(GBR).A retrospective study involving 29 patients treated with GBR technique,which... To evaluate the clinical efficacy of concentrated growth factors(CGFs)combined with mineralized collagen(MC)in guided bone regeneration(GBR).A retrospective study involving 29 patients treated with GBR technique,which was performed either CGF and MC complexes or MC alone.Implants were inserted simultaneously and cone-beam computed tomography was taken immediately,at 3 and 6 months postoperation.Questionnaires were completed by all patients so as to evaluate the main symptoms and daily activities during the first week after surgery.The outcomes of the two groups were statistically compared.All implants healed uneventfully.Patients in both groups suffered from different levels of discomfort for the reason of swelling,pain and chewing impairment on 1-2 days.Meanwhile,swelling of the Trial group was weaker than the Control group.When compared with the Control group,pain levels in Trial group were more rapidly reduced and patients took fewer analgesics from Day 3.Furthermore,the reconstitution mean value of the graft was thicker at 3 and 6 months in Trial group.CGFs complex with MC were beneficial to relieve the clinical symptoms,promote the peri-implant bone regeneration and shorten the healing time. 展开更多
关键词 concentrated growth factors mineralized collagen guided bone regeneration bone augmentation OSSEOINTEGRATION
Study on repairing canine mandibular defect with porous Mg-Sr alloy combined with Mg-Sr alloy membrane 认领
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作者 Shanning Zhang Xirao Sun +3 位作者 Chunyu Kang Man Yang Yuan Zhao Chengyue Wang 《再生生物材料(英文版)》 SCIE 2020年第3期331-336,共6页
To discuss the feasibility of the application of porous Mg-Sr alloy combined with Mg-Sr alloy membrane in the repair of mandibular defects in dogs.The second and third mandibular premolars on both sides were extracted... To discuss the feasibility of the application of porous Mg-Sr alloy combined with Mg-Sr alloy membrane in the repair of mandibular defects in dogs.The second and third mandibular premolars on both sides were extracted from six dogs.The model of mandible buccal fenestration bone defects were prepared after the sockets healed.Twelve bone defects were randomly divided into groups A and B,then Mg-Sr alloy was implanted in bone defects of group A and covered by Mg-Sr alloy membrane while Mg-Sr alloy was implanted in bone defects of group B and covered by mineralized collagen membrane.Bone defects observed on cone beam computed tomographic images and comparing the gray value of the two groups after 4,8 and 12 weeks.After 12 weeks,the healing of bone defects were evaluated by gross observation,X-ray microscopes and histological observation of hard tissue.Bone defects in each group were repaired.At 8 and 12 weeks,the gray value of group A was higher than that of group B(P<0.05).At 12 weeks,the bone volume fraction of group A was higher than that of group B(P<0.05).The newly woven bone in group A is thick and arranged staggered,which was better than that of group B.Porous Mg-Sr alloy combined with Mg-Sr alloy membrane could further promote the repair of mandibular defects,and obtain good osteogenic effect. 展开更多
关键词 Mg-Sr alloy Mg-Sr alloy membrane mineralized collagen membrane mandibular defects guided bone regeneration
Vitrectomy with air tamponade for surgical repair of rhegmatogenous retinal detachment by eye position guided fluid-air exchange 认领
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作者 Yu-Hong Cheng Hua Wang +6 位作者 Bo Li Meng Ji Qiang Shi Yun Qi Ya-Guang Hu An-Ming Xie Cheng Pei 《国际眼科杂志:英文版》 SCIE CAS 2020年第9期1417-1422,共6页
AIM:To observe the efficacy and safety of pars plana vitrectomy(PPV)with eye position guided fluid-air exchange(FAX)and air to mponade in the treatment of rhegmatogenous retinal detachment(RRD).METHODS:RRD patients wi... AIM:To observe the efficacy and safety of pars plana vitrectomy(PPV)with eye position guided fluid-air exchange(FAX)and air to mponade in the treatment of rhegmatogenous retinal detachment(RRD).METHODS:RRD patients without severe proliferative vitreoretinopathy(PVR)C1 or more were enrolled.All patients underwent PPV combining with air tamponade.During operation,the primary retinal break(s)were placed at lower site and subretinal fluid was aspirated through the break(s)at the same time when eye position guided FAX was proceeding.Sufficient laser spots were made to seal the retinal break(s)after FAX,and filtered air was left in vitreous cavity as to mponade agent finally.The main outcomes were primary and final success rates,best corrected visual acuity(BCVA),and the secondary outcomes were rate of postoperative cataract surgery and high intraocular pressure.RESULTS:A total of 37 eyes(20 males and 17 females)with a follow-up time of≥6 mo were included.The range of RRD was 5.6±1.8 h,and the number of retinal breaks was 1.9±1.2.The breaks located at inferior quadrants(between 3:00 and 9:00)in 5 cases(13.5%),and both superior and inferior breaks were found in 3 cases(8.1%).A total of 25 cases(67.6%)with macular detached involvement,9 cases(24.3%)with intraocular lens,and 8 patients(21.6%)were treated with phacoemulsification and intraocular lens implantation together.The success rate of primary retinal reattachment was 100%(37/37).At 6 mo postoperatively,BCVA(logMAR)was increased from 1.13±1.07 to 0.23±0.15(P<0.001).Phacoemulsification combined with intraocular lens implantation was performed in 2 patients(5.4%),and one of them underwent macular epiretinal membrane peeling in addition(2.7%).Furthermore,high intraocular pressure was found in 4 cases(10.8%).CONCLUSION:PPV with air tamponade by eye position guided FAX can achieve a high reattachment success rate in the management of patients with RRD,and it has the advantages of short postoperative prone time and fewer operative complications. 展开更多
关键词 pars plana vitrectomy eye position guided FAX air tamponade rhegmatogenous retinal detachment
Fast-armored target detection based on multi-scale representation and guided anchor 认领
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作者 Fan-jie Meng Xin-qing Wang +2 位作者 Fa-ming Shao Dong Wang Xiao-dong Hu 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2020年第4期922-932,共11页
Focused on the task of fast and accurate armored target detection in ground battlefield,a detection method based on multi-scale representation network(MS-RN) and shape-fixed Guided Anchor(SF-GA)scheme is proposed.Firs... Focused on the task of fast and accurate armored target detection in ground battlefield,a detection method based on multi-scale representation network(MS-RN) and shape-fixed Guided Anchor(SF-GA)scheme is proposed.Firstly,considering the large-scale variation and camouflage of armored target,a new MS-RN integrating contextual information in battlefield environment is designed.The MS-RN extracts deep features from templates with different scales and strengthens the detection ability of small targets.Armored targets of different sizes are detected on different representation features.Secondly,aiming at the accuracy and real-time detection requirements,improved shape-fixed Guided Anchor is used on feature maps of different scales to recommend regions of interests(ROIs).Different from sliding or random anchor,the SF-GA can filter out 80% of the regions while still improving the recall.A special detection dataset for armored target,named Armored Target Dataset(ARTD),is constructed,based on which the comparable experiments with state-of-art detection methods are conducted.Experimental results show that the proposed method achieves outstanding performance in detection accuracy and efficiency,especially when small armored targets are involved. 展开更多
关键词 RED image RPN Fast-armored target detection based on multi-scale representation and guided anchor
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MRS联合FL导航手术治疗幕上高级别胶质瘤疗效观察 认领
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作者 陈曦 《海南医学》 CAS 2020年第14期1800-1803,共4页
目的比较磁共振波谱分析(MRS)联合荧光素钠(FL)导航手术与常规显微外科手术治疗幕上高级别胶质瘤的临床效果。方法回顾性分析2017年1月至2019年1月期间自贡市第四人民医院神经外科收治的80例幕上高级别胶质瘤患者的临床资料,其中51例实... 目的比较磁共振波谱分析(MRS)联合荧光素钠(FL)导航手术与常规显微外科手术治疗幕上高级别胶质瘤的临床效果。方法回顾性分析2017年1月至2019年1月期间自贡市第四人民医院神经外科收治的80例幕上高级别胶质瘤患者的临床资料,其中51例实施MRS联合FL导航手术,纳入观察组,29例实施常规显微外科手术,纳入对照组。比较两组患者围术期指标(手术时间、住院天数)、肿瘤切除率、术后肢体功能运动情况、术后3个月、6个月、12个月生存质量[卡氏功能状态评分(KPS)]评分,以及术后随访情况[肿瘤无进展生存时间(PFS)、1年生存率]。结果两组患者的手术时间比较差异无统计学意义(P>0.05);观察组患者的住院天数为(7.22±0.85)d,明显短于对照组的(24.68±0.73)d,肿瘤全切率为90.20%,明显高于对照组的51.72%,差异均有统计学意义(P<0.05);观察组患者术后偏瘫或肌力下降比例为9.80%(5/51),低于对照组的44.83%(13/29),差异有统计学意义(P<0.05);观察组和对照组患者KPS评分术后3个月[(91.97±4.26)分vs(88.73±6.58)分]、6个月[(85.47±5.95)分vs(81.33±4.79)分]、12个月[(81.92±7.32)分vs(7.48±6.73)分]比较,观察组明显高于对照组,差异均有统计学意义(P<0.05);观察组患者平均PFS和1年生存率分别为(13.37±1.75)个月、78.43%,分别与对照组的(12.72±1.69)个月、75.86%比较,差异均无统计学意义(P>0.05)。结论与常规显微外科手术相比,MRS联合FL导航手术治疗幕上高级别胶质瘤可提高全切率,同时更好地保护患者的肢体运动功能,提高生存质量,但暂无证据表明该手术可延长患者生存期。 展开更多
关键词 磁共振波谱分析 荧光素钠 导航 显微手术 幕上高级别胶质瘤 疗效
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A review of dual-spin projectile stability 认领
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作者 James Norris Amer Hameed +1 位作者 John Economou Simon Parker 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2020年第1期1-9,共9页
This paper gives a succinct review of dual-spinprojectile stability and some technologies relating to them.It describes how the traditional stability factors from linear projectile theory are modified to better descri... This paper gives a succinct review of dual-spinprojectile stability and some technologies relating to them.It describes how the traditional stability factors from linear projectile theory are modified to better describe a controlled dual-spin projectile.Finally,it reviews works which have investigated how different aspects of a controlled dual-spin design can affect flight stability,primarily airframe structure and canard properties.A conclusion is given,highlighting important guidelines from the enclosed discussions. 展开更多
关键词 Guided PROJECTILES Dual-spin Gyroscopic Dynamic STABILITY CANARDS
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Sterols possess immunomodulatory property:Activity guided isolation and in vitro screening of phytoconstituents of Pongamia glabra and Ficus glomerata 认领
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作者 Sanjeev Heroor Arunkumar Beknal +2 位作者 Nitin Mahurkar Suresh Hiremath Shivkumar Inamdar 《中草药:英文版》 CAS 2020年第3期310-315,共6页
Objective:To isolate the phytoconstituents from the methanolic extracts of the stem bark of Pongamia glabra and Ficus glomerata,characterize spectroscopically and screen for in vitro immunomodulatory activity on human... Objective:To isolate the phytoconstituents from the methanolic extracts of the stem bark of Pongamia glabra and Ficus glomerata,characterize spectroscopically and screen for in vitro immunomodulatory activity on human neurophils.Methods:A flavonoid(PGF)and an alkaloidal compound(PGA)from the extract of P.glabra and a steroidal compound(FGS)and tannin fraction(FGT)from the extract of F.glomerata were isolated using column chromatography technique and were subjected for the spectroscopic(FT-IR,1HNMR and LC-MS)and TLC studies to identify the compounds.The isolated compounds were screened for in vitro immunomodulatory activity on human neutrophils using nitroblue tetrazolium(NBT)dye test,phagocytosis of Candida albicans and neutrophil locomotion and chemotaxis assay at the concentration range of 100,50,25,12.50 and 5.00μg/mL.Results:From the spectroscopic and TLC studies data,the isolated compounds were identified as glabrin(PGA),karanjin(PGF),β-sitosterol(FGS),and tannin fraction(FGT).The isolated compounds PGA,PGF,FGS,and FGT exhibited significant(P<0.05)in vitro immunomodulatory activity in all the parameters studied.Conclusion:The steroidal compound,i.e.FGS was found to be more immunopotent than all constituents alkaloid,flavonoid and tannins.Hence,these constituents could be attributed to the immunomodulatory property of the plants. 展开更多
关键词 activity guided isolation Ficus glomerate Roxb. immunomodulation Pongamia glabra Vent.
系统评价导引治疗骨质疏松症的Meta分析 认领 被引量:1
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作者 周晓宁 许金海 +5 位作者 王国栋 尹萌辰 叶洁 马俊明 莫文 施杞 《中国骨质疏松杂志》 CAS CSCD 北大核心 2020年第7期946-952,共7页
目的系统评价导引治疗骨质疏松症的有效性及安全性。方法计算机检索中、英文数据库(自建库至2019年4月)中收录的导引治疗骨质疏松症的临床随机对照文献,依据JADAD评估质量,并用Rev Man 5.3进行Meta分析。结果检索文献共289篇,纳入9篇,... 目的系统评价导引治疗骨质疏松症的有效性及安全性。方法计算机检索中、英文数据库(自建库至2019年4月)中收录的导引治疗骨质疏松症的临床随机对照文献,依据JADAD评估质量,并用Rev Man 5.3进行Meta分析。结果检索文献共289篇,纳入9篇,总样本量808例。Meta分析得出:导引+常规VS常规干预改善VAS评分[MD=-1.06,95%CI(-1.31,-0.82),P<0.00001]、腰椎骨密度[MD=0.09,95%CI(0.01,0.16),P=0.02]、股骨颈骨密度[MD=0.13,95%CI(0.00,0.25),P=0.05]、血清磷[MD=0.02,95CI(0.00,0.04),P=0.05]均优于常规治疗,且差异有统计学意义。对血清钙[MD=-0.53,95%CI(-1.48,0.41),P=0.27]、血清碱性磷酸酶[MD=-0.18,95%CI(-11.90,11.53),P=0.98]的改善未见明显差异。导引VS传统锻炼改善VAS评分[MD=-1.66,95%CI(-2.57,-0.74),P=0.0004]、腰椎骨密度[MD=0.11,95%CI(0.02,0.20),P=0.01]、股骨颈骨密度[MD=0.08,95CI(0.01,0.14),P=0.02]疗效均优于传统锻炼。结论导引治疗骨质疏松症在改善VAS评分、腰椎骨密度、股骨颈骨密度均优于常规干预,且与西药联用具有增效作用。 展开更多
关键词 骨质疏松 导引 骨密度 META分析
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Guided cell migration on a graded micropillar substrate 认领
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作者 Srikumar Krishnamoorthy Zhengyi Zhang Changxue Xu 《生物设计与制造(英文)》 CSCD 2020年第1期60-70,共11页
Cell migration is facilitated by the interaction of living cells and their local microenvironment.The local topography is one of the key factors regulating cell migration.Interaction between the surface topography and... Cell migration is facilitated by the interaction of living cells and their local microenvironment.The local topography is one of the key factors regulating cell migration.Interaction between the surface topography and the cell behaviors is critical to understanding tissue development and regeneration.In this study,a dynamic mask photolithography technique has been utilized to fabricate a surface with graded micropillars.It has been demonstrated that the cells have been successfully guided to migrate from the sparse zone to the dense zone.The cell polarization angle has been characterized in both sparse zone and the dense zone.Compared to the dense zone,the cells in the sparse zone are more aligned along the direction of the micropillar spacing gradient,which enables the guided cell migration.Moreover,the effects of the micropillar spacing gradient,micropillar diameter,and micropillar height have been investigated in terms of the cell migration speed and cell spreading area.Finally,two issues significantly affecting the cell migration have been discussed:trapped cells between the micropillars and cell clusters. 展开更多
关键词 GUIDED CELL migration GRADED MICROTOPOGRAPHY CELL POLARIZATION
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