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《北京周报:英文版》 2019年第4期10-11,共2页
Wu Mengchao,a world-famous Chinese hepatic surgeon,retired at the age of 97 on January 14. H.e was the head of the Eastern Hepatobiliary Surgery Hospital attached to the Second Military Medical University in Shanghai.
关键词 WU Mengchao Chinese HEPATIC SURGEON HEPATOBILIARY Surgery
Gadoxetic acid-enhanced magnetic resonance imaging can predict the pathologic stage of solitary hepatocellular carcinoma 预览
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作者 Yi-Chen Chou I-Ha Lao +8 位作者 Pei-Ling Hsieh Ying-Ying Su Chee-Wai Mak Ding-Ping Sun Ming-Jen Sheu Hsing-Tao Kuo Tzu-Ju Chen Chung-Han Ho Yu-Ting Kuo 《世界胃肠病学杂志:英文版》 SCIE CAS 2019年第21期2636-2649,共14页
BACKGROUND Although important for determining long-term outcome, pathologic stage of hepatocellular carcinoma (HCC) is difficult to predict before surgery. Current state-of-the-art magnetic resonance imaging (MRI) usi... BACKGROUND Although important for determining long-term outcome, pathologic stage of hepatocellular carcinoma (HCC) is difficult to predict before surgery. Current state-of-the-art magnetic resonance imaging (MRI) using gadoxetic acid provides many imaging features that could potentially be used to classify single HCC as pT1 or pT2. AIM To determine which gadoxetic acid-enhanced MRI (EOB-MRI) findings predict pathologic stage T2 in patients with solitary HCC (cT1). METHODS Pre-operative EOB-MRI findings were reviewed in a retrospective cohort of patients with solitary HCC. The following imaging features were examined: Hyperintensity in unenhanced T2-weighted images, hypointensity in unenhanced T1-weighted images, arterial enhancement, corona enhancement, washout appearance, capsular appearance, hypointensity in the tumor tissue during the hepatobiliary (HB) phase, peritumoral hypointensity in the HB phase, hypointense rim in the HB phase, intratumoral fat, hyperintensity on diffusionweighted imaging, hypointensity on apparent diffusion coefficient map, mosaic appearance, nodule-in-nodule appearance, and the margin (smooth or irregular). Surgical pathology was used as the reference method for tumor staging. Univariate and multivariate analyses were performed to identify predictors of microvascular invasion or satellite nodules. RESULTS There were 39 (34.2%;39 of 114) and 75 (65.8%;75 of 114) pathological stage T2 and T1 HCCs, respectively. Large tumor size (≥ 2.3 cm) and two MRI findings, i.e., corona enhancement [odds ratio = 2.67;95% confidence interval: 1.101-6.480] and peritumoral hypointensity in HB phase images (odds ratio = 2.203;95% confidence interval: 0.961-5.049) were associated with high risk of pT2 HCC. The positive likelihood ratio was 6.25 (95% confidence interval: 1.788-21.845), and sensitivity of EOB-MRI for detecting pT2 HCC was 86.2% when two or three of these MRI features were present. Small tumor size and hypointense rim in the HB phase were regarded as benign features. Small HCCs with hypoi 展开更多
关键词 Tumor INVASIVENESS GADOLINIUM ethoxybenzyl diethylenetriaminepentaacetic acid HEPATOBILIARY CONTRAST agent Magnetic resonance imaging Hepatocellular carcinoma
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Hepatobiliary & Pancreatic Diseases International 预览
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《国际肝胆胰疾病杂志:英文版》 SCIE CAS CSCD 2019年第4期I0006-I0008,共3页
General information Hepatobiliary&Pancreatic Diseases International is a journal published bimonthly in the English language by the First Affiliated Hospital,Zhejiang University School of Medicine,Hangzhou,China.W... General information Hepatobiliary&Pancreatic Diseases International is a journal published bimonthly in the English language by the First Affiliated Hospital,Zhejiang University School of Medicine,Hangzhou,China.We welcome original research articles,review articles,editorials,and others from any part of the world.Manuscripts are reviewed by members of the international editorial board and our expert peer reviewers,then either accepted for publication or rejected by the chief editor.Manuscripts should be submitted via https://mc03.manuscriptcentral.com/hbpdint. 展开更多
关键词 HEPATOBILIARY INFORMATION GENERAL
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Optimization of hepatobiliary phase delay time of Gd-EOB-DTPA-enhanced magnetic resonance imaging for identification of hepatocellular carcinoma in patients with cirrhosis of different degrees of severity 预览
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作者 Jian-Wei Wu Yue-Cheng Yu +2 位作者 Xian-Li Qu Yan Zhang Hong Gao 《世界胃肠病学杂志:英文版》 SCIE CAS 2018年第3期415-423,共9页
AIM To optimize the hepatobiliary phase delay time(HBPDT)of Gd-EOB-DTPA-enhanced magnetic resonance imaging(GED-MRI)for more efficient identification of hepatocellular carcinoma(HCC)occurring in different degrees of c... AIM To optimize the hepatobiliary phase delay time(HBPDT)of Gd-EOB-DTPA-enhanced magnetic resonance imaging(GED-MRI)for more efficient identification of hepatocellular carcinoma(HCC)occurring in different degrees of cirrhosis assessed by Child-Pugh(CP)score.METHODS The liver parenchyma signal intensity(LPSI),the liver parenchyma(LP)/HCC signal ratios,and the visibility of HCC at HBP-DT of 5,10,15,20,and 25 min(i.e.,DT-5,DT-10,DT-15,DT-20,and DT-25)after injection of Gd-EOB-DTPA were collected and analyzed in 73 patients with cirrhosis of different degrees of severity(including 42 patients suffering from HCC)and 18 healthy adult controls.RESULTS The LPSI increased with HBP-DT more significantly in the healthy group than in the cirrhosis group(F=17.361,P<0.001).The LP/HCC signal ratios had a significant difference(F=12.453,P<0.001)among various HBP-DT points,as well as between CP-A and CP-B/C subgroups(F=9.761,P<0.001).The constituent ratios of HCC foci identified as obvious hypointensity(+++),moderate hypointensity(++),and mild hypointensity or isointensity(+/-)kept stable from DT-10 to DT-25:90.6%,9.4%,and 0.0%in the CP-A subgroup;50.0%,50.0%,and 0.0%in the CP-B subgroup;and 0.0%,0.0%,and 100.0%in the CP-C subgroup,respectively.CONCLUSION The severity of liver cirrhosis has significant negative influence on the HCC visualization by GED-MRI.DT-10 is more efficient and practical than other HBP-DT points to identify most of HCC foci emerging in CP-A cirrhosis,as well as in CP-B cirrhosis;but an HBP-DT of 15 min or longer seems more appropriate than DT-10 for visualization of HCC in patients with CP-C cirrhosis. 展开更多
关键词 Magnetic resonance imaging Gd-EOBDTPA HEPATOBILIARY PHASE Delay time Hepatocellular carcinoma CIRRHOSIS OPTIMIZATION
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胆道疾病患者外科手术后胃肠功能恢复的临床研究 预览
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作者 刘志武 高雪梅 《中国社区医师》 2018年第36期38-39,共2页
目的:分析胆道疾病患者外科手术后给予不同处理,患者胃肠功能恢复情况。方法:收治行胆道外科手术患者253例,分两组。观察组127例(常规治疗+综合治疗)、对照组126例(常规治疗),观察围手术期不同处理方式患者术后恢复情况,对术后12h、1d、... 目的:分析胆道疾病患者外科手术后给予不同处理,患者胃肠功能恢复情况。方法:收治行胆道外科手术患者253例,分两组。观察组127例(常规治疗+综合治疗)、对照组126例(常规治疗),观察围手术期不同处理方式患者术后恢复情况,对术后12h、1d、2d 患者腹痛程度进行评分,比较两组术后并发症发生情况,检测患者胃泌素治疗前后水平变化。结果:观察组肠鸣音恢复、肛门排气用时短,且术后12h、1d、2d 疼痛评分低(P<0.05),术后观察组胃泌素水平高于对照组(P<0.05),观察组并发症发生少(P<0.05)。结论:临床对胆道手术者围手术期给予综合治疗,患者术后并发症少、恢复快、疼痛弱。 展开更多
关键词 围手术期 胃肠功能 肝胆 综合治疗
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无陪人护理新模式在肝胆胰脾外科病区的构建和应用效果 预览
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作者 刘红 任炜 郑明霞 《临床医学研究与实践》 2018年第35期161-163,共3页
目的探讨无陪人护理新模式在肝胆胰脾外科病区的构建和应用效果。方法选择宝鸡市中心医院肝胆胰脾外科病区206例患者,按照患者的入院时间分为对照组(92例,常规护理)及试验组(114例,无陪人护理),观察两组患者的护理效果。结果试验组患者... 目的探讨无陪人护理新模式在肝胆胰脾外科病区的构建和应用效果。方法选择宝鸡市中心医院肝胆胰脾外科病区206例患者,按照患者的入院时间分为对照组(92例,常规护理)及试验组(114例,无陪人护理),观察两组患者的护理效果。结果试验组患者的住院天数、下床活动时间、排气时间及排便时间均短于对照组(P<0.05)。试验组患者住院期间不良反应总发生率、护理不良事件总发生率明显低于对照组(P<0.05)。试验组患者的治疗行为、环境及生活服务满意度及综合满意度均明显高于对照组(P<0.05)。结论无陪人护理新模式有助于促进肝胆胰脾外科病区患者的术后恢复,且护理满意度高,值得临床推广。 展开更多
关键词 无陪人护理新模式 肝胆胰脾外科病区 护理满意度
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Multidisciplinary management of hepatobiliary tumors in the era of precision medicine 预览
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作者 Jian-Zhen Lin Yi Bai +7 位作者 An-Qiang Wang Jun-Yu Long Wei-Yu Xu Ke Hu Lin Zhao Jie Pan Xin-Ting Sang Hai-Tao Zhao 《国际肝胆胰疾病杂志:英文版》 SCIE CAS CSCD 2018年第5期381-382,共2页
Hepatobiliary tumor(HBT),one of the leading causes of cancer deaths globally,is more frequent in East Asia including China[1].HBT includes liver cancer,cholangiocarcinoma and gallbladder cancer.HBT burden varies marke... Hepatobiliary tumor(HBT),one of the leading causes of cancer deaths globally,is more frequent in East Asia including China[1].HBT includes liver cancer,cholangiocarcinoma and gallbladder cancer.HBT burden varies markedly by gender and geographic region due to the exposure of risk factors.Majority of the hepatocellular carcinomas are associated with hepatitis B-type virus infection[2],and approximate 70%patients were male in China.Other risk factors include infections(hepatitis C virus),aflatoxins,flukes in endemic areas,behavioral factors(alcohol,tobacco),metabolic factors(diabetes,obesity)and congenital disease(bile duct cyst).The pathogenesis of HBTs are complex and HBTs possess high-level tumor heterogeneity(both intra-and intertumor)[3,4],it is important to conduct a comprehensive assessment for every patient before making decision in treatment,which needs multidisciplinary management efforts. 展开更多
关键词 HEPATOBILIARY tumor HEPATITIS C virus EAST Asia
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Helicobacter pylori and extragastric diseases:A review 预览
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作者 Antonietta Gerarda Gravina Rocco Maurizio Zagari +3 位作者 Cristiana De Musis Lorenzo Romano Carmelina Loguercio Marco Romano 《世界胃肠病学杂志:英文版》 SCIE CAS 2018年第29期3204-3221,共18页
Helicobacter pylori(H.pylori)infection is very common and affects approximately half of the world population.It causes gastric diseases,but some authors have reported an association of H.pylori infection with other sy... Helicobacter pylori(H.pylori)infection is very common and affects approximately half of the world population.It causes gastric diseases,but some authors have reported an association of H.pylori infection with other systemic manifestations beginning in 1994.The list of potential effects of H.pylori outside the stomach includes a number of extragastric manifestations and we focused on neurological,dermatological,hematologic,ocular,cardiovascular,metabolic,allergic,and hepatobiliary diseases.This review discusses these important reported manifestations that are not related to the gastrointestinal tract. 展开更多
关键词 Helicobacter pylori Extragastric disease NEUROLOGICAL DISEASES Dermatological DISEASES HEMATOLOGIC DISEASES OCULAR DISEASES Cardiovascular DISEASES Metabolic DISEASES ALLERGIC DISEASES HEPATOBILIARY DISEASES
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MR with Gd-EOB-DTPA in assessment of liver nodules in cirrhotic patients 预览
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作者 Riccardo Inchingolo Riccardo Faletti +4 位作者 Luigi Grazioli Eleonora Tricarico Marco Gatti Anna Pecorelli Davide Ippolito 《世界肝病学杂志:英文版(电子版)》 2018年第7期462-473,共12页
To date the imaging diagnosis of liver lesions is based mainly on the identification of vascular features,which are typical of overt hepatocellular carcinoma(HCC),but the hepatocarcinogenesis is a complex and multiste... To date the imaging diagnosis of liver lesions is based mainly on the identification of vascular features,which are typical of overt hepatocellular carcinoma(HCC),but the hepatocarcinogenesis is a complex and multistep event during which,a spectrum of nodules develop within the liver parenchyma,including benign small and large regenerative nodule(RN),low-grade dysplastic nodule(LGDN),high-grade dysplastic nodule(HGDN),early HCC,and well differentiated HCC.These nodules may be characterised not only on the basis of their respective different blood supplies,but also on their different hepatocyte function.Recently,in liver imaging the introduction of hepatobiliary magnetic resonance imaging contrast agent offered the clinicians the possibility to obtain,at once,information not only related to the vascular changes of liver nodules but also information on hepatocyte function.For this reasons this new approach becomes the most relevant diagnostic clue for differentiating low-risk nodules(LGDN-RN)from highrisk nodules(HGDN/early HCC or overt HCC)and consequently new diagnostic algorithms for HCC have been proposed.The use of hepatobiliary contrast agents is constantly increasing and gradually changing the standard of diagnosis of HCC.The main purpose of this review is to underline the added value of Gd-EOB-DTPA in early-stage diagnoses of HCC.We also analyse the guidelines for the diagnosis and management of HCC,the key concepts of HCC development,growth and spread and the imaging appearance of precursor nodules that eventually may transform into overt HCC. 展开更多
关键词 HEPATOBILIARY CONTRAST materials CIRRHOSIS Gadoxetic acid Magnetic resonance imaging LIVER
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Acute and chronic hepatobiliary manifestations of sickle cell disease: A review 预览
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作者 Rushikesh Shah Cesar Taborda Saurabh Chawla 《世界胃肠病理生理学杂志:英文版(电子版)》 2017年第3期108-116,共9页
Sickle cell disease(SCD) is a common hemoglobinopathy which can affect multiple organ systems in the body. Within the digestive tract, the hepatobiliary system is most commonly affected in SCD. The manifestations rang... Sickle cell disease(SCD) is a common hemoglobinopathy which can affect multiple organ systems in the body. Within the digestive tract, the hepatobiliary system is most commonly affected in SCD. The manifestations range from benign hyperbilirubinemia to overt liver failure, with the spectrum of acute clinical presentations often referred to as 'sickle cell hepatopathy'. This is an umbrella term referring to liver dysfunction and hyperbilirubinemia due to intrahepatic sickling process during SCD crisis leading to ischemia, sequestration and cholestasis. In this review, we detail the pathophysiology, clinical presentation and biochemical features of various acute and chronic hepatobiliary manifestations of SCD and present and evaluate existing evidence with regards to management of this disease process. We also discuss recent advances and controversies such as the role of liver transplantation in sickle cell hepatopathy and highlight important questions in this field which would require further research. Our aim with this review is to help increase the understanding, aid in early diagnosis and improve management of this important disease process. 展开更多
关键词 镰刀房间疾病 HEPATOPATHY HEPATOBILIARY Intrahepatic cholestasis 肝的隐遁 镰刀房间肝的危机 镰刀房间 cholangiopathy 肝移植 铁超载
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THANKS 预览
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《国际肝胆胰疾病杂志:英文版》 SCIE CAS CSCD 2017年第6期671-672,共2页
The editorial staff of the Hepatobiliary & Pancreatic Diseases International are grateful to the listed reviewers for their contributions to the improvement of the manuscripts received and the publication of the j... The editorial staff of the Hepatobiliary & Pancreatic Diseases International are grateful to the listed reviewers for their contributions to the improvement of the manuscripts received and the publication of the journal in the year of 2017 (November 1, 2016 to October 31, 2017).Eman Abushady Paola Aceto Adreas Adler Nobuhisa Akamatsu Sheikh Mohammad Fazle Akbar Antonio Maria AlfanoFrancesco Ardito Koji Asai Federico Aucejo Dagfinn Aune Serin Ayfer Shashwatee Bagchi Peter Bannasch Luis M Barrera Giacomo Batignani George Berci Kimberly Bertens Chandra Shekhar Bhati Hubert E Blum Ugo Boggi Richard J Bold Giuseppe Borzellino Martin Brand William R Brugge Helge Bruns Tony Bruns Raffaele Brustia Trond A Buanes 展开更多
关键词 HEPATOBILIARY & PANCREATIC DISEASES INTERNATIONAL
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对行肝胆外科手术的患者在术后进行强化引流护理的效果研究 预览 被引量:3
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作者 陈琼霞 《当代医药论丛》 2017年第9期7-9,共3页
目的:探讨对进行肝胆外科手术的患者在术后进行强化引流护理的效果。方法 :选取近几年邛崃市医疗中心医院收治的100例进行肝胆外科手术的患者作为研究对象。这些患者在术后均放置了引流管。随机将这些患者分为强化组和常规组。在术后... 目的:探讨对进行肝胆外科手术的患者在术后进行强化引流护理的效果。方法 :选取近几年邛崃市医疗中心医院收治的100例进行肝胆外科手术的患者作为研究对象。这些患者在术后均放置了引流管。随机将这些患者分为强化组和常规组。在术后对所有患者均进行常规护理。在此基础上,为强化组患者进行强化引流护理。然后比较两组患者并发症的发生情况、接受护理的效果及对护理服务的满意度。结果 :强化组患者接受护理的效果、并发症的发生率及对护理服务的总满意率均优于常规组患者,差异具有统计学意义(P〈0.05)。结论 :对进行肝胆外科手术的患者在术后进行强化引流护理的效果显著,能降低其并发症的发生率,提高其对护理服务的满意度。 展开更多
关键词 肝胆外科 手术 引流 护理 并发症
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Hepatobiliary & Pancreatic Diseases International 预览
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《国际肝胆胰疾病杂志:英文版》 SCIE CAS CSCD 2017年第6期566-569,共4页
General information Hepatobiliary & Pancreatic Diseases International is a journal published bimonthly in the English language by the First Affiliated Hospital, Zhejiang University School of Medicine,Hangzhou, Chi... General information Hepatobiliary & Pancreatic Diseases International is a journal published bimonthly in the English language by the First Affiliated Hospital, Zhejiang University School of Medicine,Hangzhou, China. We welcome original research articles, review articles,editorials, and others from any part of the world. Manuscripts are reviewed by members of the international editorial board and our expert peer reviewers, then either accepted for publication or rejected by the chief editor. Manuscripts should be submitted via https://mc03.manuscriptcentral.com/hbpdint.Most of submissions accepted for publication may undergo revisions recommended by the reviewers, editors or statistical advisers. A decision takes from two weeks to three months, the longer period being due to the multiple reviews needed for articles likely to be accepted. Publication varies from two to six months after final acceptance.Proofs of edited articles and illustrations are sent to the corresponding author for correction and reply to any queries from editors. A sample copy of the journal containing the articles will be forwarded to the corresponding author within a few days of publication. 展开更多
关键词 GENERAL INFORMATION HEPATOBILIARY & PANCREATIC DISEASES INTERNATIONAL
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Bisphosphonates as potential adjuvants for patients withcancers of the digestive system 预览
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作者 Celina Ang Erin Doyle Andrea Branch 《世界胃肠病学杂志:英文版》 SCIE CAS 2016年第3期906-916,共11页
Best known for their anti-resorptive activity in bone,bisphosphonates (BPs) have generated interest aspotential antineoplastic agents given their pleiotropicbiological effects which include antiproliferative,antiang... Best known for their anti-resorptive activity in bone,bisphosphonates (BPs) have generated interest aspotential antineoplastic agents given their pleiotropicbiological effects which include antiproliferative,antiangiogenic and immune-modulating properties.Clinical studies in multiple malignancies suggest thatBPs may be active in the prevention or treatment ofcancer. Digestive tract malignancies represent a largeand heterogeneous disease group, and the activityof BPs in these cancers has not been extensivelystudied. Recent data showing that some BPs inhibithuman epidermal growth factor receptor (HER)signaling highlight a potential therapeutic opportunityin digestive cancers, many of which have alterations inthe HER axis. Herein, we review the available evidenceproviding a rationale for the repurposing of BPs asa therapeutic adjunct in the treatment of digestivemalignancies, especially in HER-driven subgroups. 展开更多
关键词 BISPHOSPHONATES Cancer GASTROINTESTINAL HEPATOBILIARY Human EPIDERMAL growth FACTOR
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肝胆胰疾病合并糖尿病患者围手术期的护理 预览 被引量:1
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作者 宮长宇 《糖尿病新世界》 2016年第7期136-137,共2页
目的 探讨肝胆胰疾病合并糖尿病患者围手术期的护理效果.方法 择取该院收治的50例肝胆胰疾病合并糖尿病患者作为研究对象,收治年限在2012年4月―2015年5月之间,按照随机化的原则将所有患者分为各有25例患者的对照组和观察组,对照组采用... 目的 探讨肝胆胰疾病合并糖尿病患者围手术期的护理效果.方法 择取该院收治的50例肝胆胰疾病合并糖尿病患者作为研究对象,收治年限在2012年4月―2015年5月之间,按照随机化的原则将所有患者分为各有25例患者的对照组和观察组,对照组采用常规护理,观察组采用围术期综合护理干预措施,分析两组护理方法的临床效果.结果 观察组肝胆胰疾病合并糖尿病患者并发症发生率(4.00%)及平均住院时间(5.43±1.13)d明显优于对照组(P〈0.05).结论 给予肝胆胰疾病合并糖尿病患者围手术期全程护理干预措施,能够有效降低并发症发生率,缩短患者的住院时间,值得推广使用. 展开更多
关键词 肝胆胰 糖尿病 围手术期 护理
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腹腔镜肝胆胰脾手术策略与技巧 被引量:6
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作者 胡三元 展翰翔 《中华消化外科杂志》 CAS CSCD 北大核心 2016年第9期868-871,共4页
腹腔镜肝胆胰脾手术临床应用日益广泛,但该类手术复杂,术后并发症发生率高。术者应熟悉正常解剖与变异,熟练掌握术中出血的预防与处理,针对不同组织特点,采用不同离断方法。另外消化道重建是腹腔镜肝胆胰手术的技术瓶颈与难点,强... 腹腔镜肝胆胰脾手术临床应用日益广泛,但该类手术复杂,术后并发症发生率高。术者应熟悉正常解剖与变异,熟练掌握术中出血的预防与处理,针对不同组织特点,采用不同离断方法。另外消化道重建是腹腔镜肝胆胰手术的技术瓶颈与难点,强调学习曲线与团队配合,并根据患者具体病情选择不同的吻合方式。3D腹腔镜及达芬奇手术机器人手术系统的应用极大地促进了复杂腹腔镜肝胆胰脾手术的发展与应用。围术期的综合管理及术后加速康复理念的应用是患者术后安全快速康复的保障,进而充分体现微创外科的优势。 展开更多
关键词 肝胆胰脾疾病 外科手术 加速康复外科 腹腔镜检查
柔性管理在肝胆外科护理工作中的应用分析 预览 被引量:2
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作者 韩云红 《中国卫生产业》 2015年第15期158-159,共2页
目的为了进一步提高肝胆外科护士工作积极性并降低医患矛盾的发生几率,分析和探讨柔性管理的价值和意义。方法抽取60例于2013年1月—2015年1月在该院肝胆外科工作的护理人员作为研究对象并按照管理模式的不同将其分为观察组和对照组各30... 目的为了进一步提高肝胆外科护士工作积极性并降低医患矛盾的发生几率,分析和探讨柔性管理的价值和意义。方法抽取60例于2013年1月—2015年1月在该院肝胆外科工作的护理人员作为研究对象并按照管理模式的不同将其分为观察组和对照组各30例,其中对照组护理人员实施传统的管理办法,而观察组护理人员则采取柔性管理,对比和分析两组的护理质量。结果经过对比分析发现,对照组在护理质量(明显不如观察组的,两组比较差异有统计学意义(P〈0.05)。结论将柔性管理应用到肝胆外科护理人员的日常管理,不仅可以显著提高患者的满意度,而且提高了护理质量,值得推广和应用。 展开更多
关键词 柔性管理 护理 肝胆外科
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Laparoscopic vs open approach to resection of hepatocellular carcinoma in patients with known cirrhosis:Systematic review and meta-analysis 预览
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作者 Ahmed Twaij Philip H Pucher +3 位作者 Mikael H Sodergren Tamara Gall Ara Darzi Long R Jiao 《世界胃肠病学杂志:英文版(电子版)》 SCIE CAS 2014年第25期8274-8281,共8页
AIM: To review the currently available literature comparing laparoscopic to open resection of hepatocellular carcinoma(HCC) in patients with known liver cirrhosis.METHODS: A literature search of MEDLINE, EMBASE, and C... AIM: To review the currently available literature comparing laparoscopic to open resection of hepatocellular carcinoma(HCC) in patients with known liver cirrhosis.METHODS: A literature search of MEDLINE, EMBASE, and Cochrane databases was conducted. The search terms used included(laparoscopic OR laparoscopy) AND(hepatic or liver) AND(surgery or resection) AND 'hepatocellular carcinoma' AND(cirrhosis or cirrhotic). Furthermore, to widen the search, we also used the 'related articles' section. Studies reporting a comparison of outcomes and methods of open vs laparoscopic hepatic resection for HCC in patients with liver cirrhosis were included. Meta-analysis of results was performed using a random effects model to compute relative risk(RR) and for dichotomous variablesand standard mean differences(SMD) for continuous variables.RESULTS: A total of 420 patients from 4 cohort studies were included in final analysis. Patients undergoing laparoscopic procedures had statistically less blood loss compared to the open cohort, SMD of-1.01(95%CI:-1.23-0.79), P < 0.001, with a reduced risk of transfusion, RR = 0.19(95%CI: 0.09-0.38), P < 0.001. A wider clearance at tumour resection margins was achieved following a laparoscopic approach, SMD of 0.34(95%CI: 0.08-0.60), P = 0.011. No significant difference was noted between laparoscopic and open resection operative times, SMD of-0.15(95%CI: 0.35-0.05), P = 0.142. The overall RR of suffering from postoperative morbidity is 0.25 in favour of the open surgery cohort(95%CI: 0.17-0.37), P < 0.001. Patients under-going laparoscopic surgery had significantly shorter length of stays in hospital compared to the open cohort, SMD of-0.53(95%CI:-0.73 to-0.32), P < 0.001.CONCLUSION: This review suggests that laparoscopic resection of hepatocellular carcinoma in patients with cirrhosis is safe and may provide improved patient outcomes when compared to the open technique. 展开更多
关键词 LAPAROSCOPIC HEPATOCELLULAR carcinoma CIRRHOSIS He
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甲亢患者肝胆损害的探讨 预览 被引量:2
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作者 张燕 《当代医学》 2014年第4期91-92,共2页
目的:对甲状腺功能亢进患者肝胆损害进行探讨。方法选取收治141例甲状腺功能亢进患者,同时收集50例正常人进行对比,分析检查结果。结果在B超下观察,观察组患者具体情况为:42例肝肿大,7例脂肪肝,16例胆囊炎,6例肝硬化;对照组有... 目的:对甲状腺功能亢进患者肝胆损害进行探讨。方法选取收治141例甲状腺功能亢进患者,同时收集50例正常人进行对比,分析检查结果。结果在B超下观察,观察组患者具体情况为:42例肝肿大,7例脂肪肝,16例胆囊炎,6例肝硬化;对照组有2例脂肪肝,2例胆囊炎。结论作为甲亢患者最大的并发症,肝胆损害的程度主要跟患者的病情有关,临床上需要加强治疗。 展开更多
关键词 甲状腺功能亢进 肝胆 B超
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A Primary Hepatobiliary Neoplasia in a Persian Cat 预览
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作者 Mohamed Shokry E1-Sayed Berbish Iman Shaheed 《生命科学(ISSN1934-7391)》 2014年第6期529-532,共4页
关键词 肝肿瘤 波斯猫 病理组织学 健康问题 临床症状 化验结果 超声检查 决定性
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