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Hirudotherapy attenuates arthritic pain in patients with various chronic pain syndromes: A retrospective analysis 认领
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作者 Johannes Loeser Brigitte Layer +3 位作者 Christopher Plata Klaus-Maria Perrar Tim Hucho Rebecca Kulbida 《结合医学学报:英文版》 SCIE CAS CSCD 2020年第5期425-433,共9页
Objective: Osteoarthritis is a degenerative disease that affects synovial joints. Micro-injuries of articular structures initiate inflammatory processes, leading to persistent pain. Due to various risk factors,osteoar... Objective: Osteoarthritis is a degenerative disease that affects synovial joints. Micro-injuries of articular structures initiate inflammatory processes, leading to persistent pain. Due to various risk factors,osteoarthritis is often diagnosed in multimorbid patients. This makes pain management one of the key challenges, with a consistent need for new therapeutic strategies. Hence, complementary and integrative methods such as hirudotherapy have become increasingly important, even though their mechanisms of action are not entirely understood.Methods: We retrospectively analyzed the longitudinal effect of a single leech application on osteoarthritic joints in a heterogenic cohort of 24 cases with various chronic pain syndromes. We assessed articular pain intensity ratings and movability of the treated joint after one-time leeching for up to 12 months.We further investigated the effect of hirudotherapy on the systemic pain status and multimodal treatment strategies of the patients.Results: There was a significant reduction in pain intensity ratings at the joint of leech application for up to 12 months after treatment. The improvements in pain intensities were independent of the form of osteoarthritis treated. In addition, we saw a considerable enhancement in local movability of the treated joint. Hirudotherapy did not seem to influence the systemic pain status as well as the previously established individualized multimodal treatment model of the patients.Conclusion: Leeching as an adjuvant therapy has a great potential especially in terms of safety and longterm outcome. 展开更多
关键词 Hirudotherapy Medicinal leeching Chronic pain syndromes Pain management OSTEOARTHRITIS
Treatment of diabetic foot ulcer with medicinal leech therapy and honey curcumin dressing: a case report 认领
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作者 Shirbeigi Laila Eghbalian Fatemeh Bakhtyari Lida 《TMR传统医学研究》 2019年第6期338-344,共7页
Background:Diabetic foot ulcers(DFUs)are common in patients with diabetes.The mortality rate of DFUs is ranked the highest after cancer.With advancements in modern medicine,leech therapy,a traditional treatment method... Background:Diabetic foot ulcers(DFUs)are common in patients with diabetes.The mortality rate of DFUs is ranked the highest after cancer.With advancements in modern medicine,leech therapy,a traditional treatment method for chronic wounds in Iranian medicine,has proven effective in relieving venous congestion.Herein,we aimed to observe the curative effects of leech therapy in combination with honey and curcumin dressing in a 77-year-old patient with a diabetic foot ulcer(UFC).Methods:Two medium-sized medicinal leeches were placed surrounding a grade 2 wound,based on Wagner’s classification system,located on the right first toe.The patient reported a visual analogue scale(VAS)score of 8.After leech therapy,the wound was covered with honey and curcumin,followed by oral administration of ciprofloxacin for 10 days.Results:Pain increased immediately after leech therapy(VAS:9-10)but decreased significantly(VAS:6)2 days after the therapy.At the end of the 2nd day,pain completely disappeared.After 3 weeks,there was no wound on the toe.After 12 weeks,there were no traces of the wound.Conclusion:Leech therapy in combination with honey and curcumin dressing is effective against disease progression in patients with DFUs. 展开更多
关键词 Hirudotherapy LEECH THERAPY DIABETIC FOOT ulcer GANGRENE DIABETIC FOOT wound Medicinal LEECH
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Beneficial effects of hirudotherapy in a chronic case of complex regional pain syndrome 认领
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作者 Rebecca Kulbida Alexander Mathes Johannes Loeser 《结合医学学报:英文版》 CAS CSCD 2019年第5期383-386,共4页
We report about hirudotherapy in a patient with chronic complex regional pain syndrome(CRPS) in the right hand. CRPS is a multifactorial disease associated with disabling pain as well as sensory and motor deficits. Th... We report about hirudotherapy in a patient with chronic complex regional pain syndrome(CRPS) in the right hand. CRPS is a multifactorial disease associated with disabling pain as well as sensory and motor deficits. The optimal therapeutic management is based on personalized multimodal treatment approaches;however, hirudotherapy has not been described in the available literature. To date, we have completed five medicinal leech treatments. Altogether, hirudotherapy led to rapid and substantial relief of symptoms, especially with respect to pain intensity ratings and skin temperature asymmetries. In addition, the patient’s active and passive agility of the affected limb improved obviously. 展开更多
关键词 Hirudotherapy Complex REGIONAL PAIN SYNDROME CHRONIC PAIN MEDICINAL LEECHES
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