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Modified constraint-induced movement therapy alters synaptic plasticity of rat contralateral hippocampus following middle cerebral artery occlusion 预览
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作者 Bei-Yao Gao Dong-Sheng Xu +6 位作者 Pei-Le Liu Ce Li Liang Du Yan Hua Jian Hu Jia-Yun Hou Yu-Long Bai 《中国神经再生研究:英文版》 SCIE CAS CSCD 2020年第6期1045-1057,共13页
Modified constraint-induced movement therapy is an effective treatment for neurological and motor impairments in patients with stroke by increasing the use of their affected limb and limiting the contralateral limb.Ho... Modified constraint-induced movement therapy is an effective treatment for neurological and motor impairments in patients with stroke by increasing the use of their affected limb and limiting the contralateral limb.However,the molecular mechanism underlying its efficacy remains unclear.In this study,a middle cerebral artery occlusion(MCAO)rat model was produced by the suture method.Rats received modified constraint-induced movement therapy 1 hour a day for 14 consecutive days,starting from the 7^th day after middle cerebral artery occlusion.Day 1 of treatment lasted for 10 minutes at 2r/min,day 2 for 20 minutes at 2 r/min,and from day 3 onward for 20 minutes at 4 r/min.CatWalk gait analysis,adhesive removal test,and Y-maze test were used to investigate motor function,sensory function as well as cognitive function in rodent animals from the 1st day before MCAO to the 21^st day after MCAO.On the 21^st day after MCAO,the neurotransmitter receptor-related genes from both contralateral and ipsilateral hippocampi were tested by micro-array and then verified by western blot assay.The glutamate related receptor was shown by transmission electron microscopy and the glutamate content was determined by high-performance liquid chromatography.The results of behavior tests showed that modified constraint-induced movement therapy promoted motor and sensory functional recovery in the middle cerebral artery-occluded rats,but had no effect on cognitive function.The modified constraint-induced movement therapy upregulated the expression of glutamate ionotropic receptor AMPA type subunit 3(Gria3)in the hippocampus and downregulated the expression of the beta3-adrenergic receptor gene Adrb3 and arginine vasopressin receptor 1 A,Avprla in the middle cerebral artery-occluded rats.In the ipsilateral hippocampus,only Adra2 a was downregulated,and there was no significant change in Gria3.Transmission electron microscopy revealed a denser distribution the more distribution of postsynaptic glutamate receptor 2/3,which is an a-amino-3-hydrox 展开更多
关键词 brain-derived neurotrophic factor glutamate HIPPOCAMPUS m CIMT middle cerebral artery occlusion modified constraint-induced movement therapy α-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid receptor
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Characterization of astrocytes and microglial cells in the hippocampal CA1 region after transient focal cerebral ischemia in rats treated with Ilexonin A 预览
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作者 Ai-Ling Xu Guan-Yi Zheng +2 位作者 Hui-Ying Ye Xiao-Dong Chen Qiong Jiang 《中国神经再生研究:英文版》 SCIE CAS CSCD 2020年第1期78-85,共8页
Ilexonin A is a compound isolated from the root of Ilex pubescens,a traditional Chinese medicine.Ilexonin A has been shown to play a neuroprotective role by regulating the activation of astrocytes and microglia in the... Ilexonin A is a compound isolated from the root of Ilex pubescens,a traditional Chinese medicine.Ilexonin A has been shown to play a neuroprotective role by regulating the activation of astrocytes and microglia in the peri-infarct area after ischemia.However,the effects of ilexonin A on astrocytes and microglia in the infarct-free region of the hippocampal CA1 region remain unclear.Focal cerebral ischemia models were established by 2-hour occlusion of the middle cerebral artery in rats.Ilexonin A(20,40 or 80 mg/kg)was administered immediately after ischemia/reperfusion.The astrocyte marker glial fibrillary acidic protein,microglia marker Iba-1,neural stem cell marker nestin and inflammation markers were detected by immunohistochemistry and western blot assay.Expression levels of tumor necrosis factor-αand interleukin 1βwere determined by enzyme linked immunosorbent assay in the hippocampal CA1 tissue.Astrocytes were activated immediately in progressively increasing numbers from 1,3,to 7 days post-ischemia/reperfusion.The number of activated astrocytes further increased in the hippocampal CA1 region after treatment with ilexonin A.Microglial cells remained quiescent after ischemia/reperfusion,but became activated after treatment with ilexonin A.Ilexonin A enhanced nestin expression and reduced the expression of tumor necrosis factor-αand interleukin 1βin the hippocampus post-ischemia/reperfusion.The results of the present study suggest that ilexonin A has a neuroprotective effect in the hippocampus after ischemia/reperfusion,probably through regulating astrocytes and microglia activation,promoting neuronal stem cell proliferation and reducing the levels of pro-inflammatory factors.This study was approved by the Animal Ethics Committee of the Fujian Medical University Union Hospital,China. 展开更多
关键词 ASTROCYTES HIPPOCAMPAL CA1 REGION ilexonin A MICROGLIA middle CEREBRAL artery OCCLUSION neural stem cell neuroprotection transient focal CEREBRAL ischemia
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Ileal Occlusion on Bezoars at Kati BSS Hospital 预览
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作者 Keita Koniba Abdoulaye Diarra +11 位作者 Sidiki Keita Issa Traore Salia Coulibaly Fadima Tall Daouda Diallo Oulematou Coulibaly Assitan Kone Boubacar Kone Mahamadou Bacary Coulibaly Daouda Konate Ismael Konare Drissa Traore 《外科学(英文)》 2019年第1期39-43,共5页
Bowel occlusions by bezoars are rare pathologies. They are due to an ob-struction of the intestinal lumen by a solid mass of fruits or undigested vegetable fibers. They are seasonal (wild fruit season from March to Ju... Bowel occlusions by bezoars are rare pathologies. They are due to an ob-struction of the intestinal lumen by a solid mass of fruits or undigested vegetable fibers. They are seasonal (wild fruit season from March to June) in the Sahel Zone. We report a case of small bowel obstruction in a 35-year-old rural man after swallowing a significant amount of wild grapes (Lannea microcarpa). We proceeded to the resection of the occluded ileal segment and performed an ileal terminal ileal anastomosis. There weren’t any complications during the postoperative site. 展开更多
关键词 BEZOARS OCCLUSION JEJUNUM SEASON
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基于结构化遮挡编码和极限学习机的局部遮挡人脸识别 预览
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作者 张芳艳 王新 许新征 《计算机应用》 CSCD 北大核心 2019年第10期2893-2898,共6页
提出使用结构化遮挡编码(SOC)结合极限学习机(ELM)的算法来处理人脸识别中的遮挡问题。首先,使用SOC去除图像上的遮挡物,将遮挡物体与人脸分离开;同时,通过局部性约束字典(LCD)来估计遮挡物的位置,建立遮挡字典和人脸字典。然后,将建立... 提出使用结构化遮挡编码(SOC)结合极限学习机(ELM)的算法来处理人脸识别中的遮挡问题。首先,使用SOC去除图像上的遮挡物,将遮挡物体与人脸分离开;同时,通过局部性约束字典(LCD)来估计遮挡物的位置,建立遮挡字典和人脸字典。然后,将建立好的人脸字典矩阵进行归一化处理,并利用ELM对归一化的数据进行分类识别。最后,在AR人脸库上进行的仿真实验结果表明,所提方法对不同遮挡物和不同区域遮挡的图像具有较好的识别率和鲁棒性。 展开更多
关键词 人脸识别 遮挡 结构化遮挡编码 局部性约束字典 极限学习机
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分块多示例学习算法的目标跟踪
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作者 张华 杨岑玉 《控制工程》 CSCD 北大核心 2019年第1期23-28,共6页
为解决目标跟踪中的光照、位姿变化及遮挡问题,提出分块多示例学习算法。该算法将目标图像分块,对每块图像片应用多示例学习算法。跟踪过程中结合样本所有图像片的综合分类器分数和每块图像片的分类器分数检测并判断跟踪过程中的光照、... 为解决目标跟踪中的光照、位姿变化及遮挡问题,提出分块多示例学习算法。该算法将目标图像分块,对每块图像片应用多示例学习算法。跟踪过程中结合样本所有图像片的综合分类器分数和每块图像片的分类器分数检测并判断跟踪过程中的光照、位姿变化,及遮挡问题。针对不同的跟踪状态,采用分类器学习率自适应调整策略,以避免"过更新"及更新不及时的问题。最后将所提方法在典型视频序列中进行验证,并与其他多示例学习算法进行对比实验。实验结果表明所提方法跟踪性能稳定,实时性强,解决了跟踪过程中的光照、位姿变化及遮挡等问题。 展开更多
关键词 目标跟踪 遮挡 分块多示例学习算法 强分类器
Minor ST-segment deviations followed by tall T waves in precordial leads caused by acute left main coronary artery occlusion:A case report
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作者 詹中群 吴立昊 +3 位作者 韩利红 李静 蔡婕 栗洋 《岭南心血管病杂志:英文版》 CAS 2019年第3期197-200,共4页
A 53-year-old male with chest pain complicated with cardiogenic shock was presented to the emergency department. The electrocardiogram showed features of acute myocardial infarction due to left main coronary artery oc... A 53-year-old male with chest pain complicated with cardiogenic shock was presented to the emergency department. The electrocardiogram showed features of acute myocardial infarction due to left main coronary artery occlusion,and minor ST-segment deviations followed by tall T waves in precordial leads with concomitant left anterior fascicular block. Emergency coronary angiogram revealed left main coronary artery complete occlusion without collateral circulation. Percutaneous intervention of the left main coronary artery was then carried out. The ECG features of a left main occlusion were discussed with this case report. 展开更多
关键词 ACUTE myocardial INFARCTION CARDIOGENIC shock left main coronary artery OCCLUSION ECG
控制入肝血流对腹腔镜治疗胆囊结石伴急性胆囊炎的疗效探讨 预览
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作者 黎秋曦 黎冬暄 +2 位作者 贺长林 刘锋 贾健锋 《医药前沿》 2019年第7期160-161,共2页
目的:对比分析肝十二指肠血流阻断与常规方法彳亍腹腔镜切除急性期胆囊结石的疗效,探讨控制肝十二指肠血流在腹腔镜胆囊切除急性期胆女的应用价值.方法:回顾分析2016年1月一2017年1月我院行腹腔镜胆囊切除的急性期胆囊结石患者共136例,... 目的:对比分析肝十二指肠血流阻断与常规方法彳亍腹腔镜切除急性期胆囊结石的疗效,探讨控制肝十二指肠血流在腹腔镜胆囊切除急性期胆女的应用价值.方法:回顾分析2016年1月一2017年1月我院行腹腔镜胆囊切除的急性期胆囊结石患者共136例,根据手术方式分为两组,腹腔镜切除术中Pringle法阻断肝十二指肠血流组(A组)70例,未行肝十二指肠血流阻断组(B组)66例,比较分析两组的治疗效果.结果:两组在住院总时间、抗生素应用时间、术后肝功能损害等方面的差异均无统计学意义(P>0.05);阻断第一肝门组的手术时间缩短、术中出血量减少、损伤性并发症少,且中转开腹率较未阻断第一肝门组发生率明显眸低(P<0.05).结论:控制肝十二指肠血流治疗胆囊结石伴急性胆囊炎患者安全有效,与未控制血流组比较,手术时间短、出血量少、损伤性并发症少、中转开腹率明显降低,值得在临床上推广使用. 展开更多
关键词 阻断 肝十二指肠韧带 腹腔镜胆囊切除 胆囊结石伴急性胆囊炎
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实验性牙移动及其引起的咬合改变对牙周神经末梢分布及相关蛋白表达的影响 预览
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作者 张羽博翰 杨鸿旭 +1 位作者 王美青 鹿蕾 《实用口腔医学杂志》 CSCD 北大核心 2019年第5期642-646,共5页
目的:研究实验性牙移动及其引起的咬合变化对牙周神经末梢标记物分布,及对牙周终末雪旺细胞标记物S-100和神经营养素-3(neurotrophin-3,NT-3)的表达。方法:用正畸皮圈推左侧上颌和右侧下颌第三磨牙向远中移动。用免疫荧光检测移动牙及... 目的:研究实验性牙移动及其引起的咬合变化对牙周神经末梢标记物分布,及对牙周终末雪旺细胞标记物S-100和神经营养素-3(neurotrophin-3,NT-3)的表达。方法:用正畸皮圈推左侧上颌和右侧下颌第三磨牙向远中移动。用免疫荧光检测移动牙及其对颌牙牙周膜中牙周神经末梢标记物蛋白基因产物9.5(protein gene product 9.5,PGP 9.5),雪旺细胞末梢标记物S-100及神经营养因子NT-3表达的变化。结果:移动牙及移动牙的对颌牙出现PGP 9.5表达的一过性降低及分布变化,以及S-100及NT-3表达的一过性增多,且S-100和NT-3有共表达。结论:实验性牙移动及其引起的咬合变化可影响牙周神经末梢标记物的分布,终末雪旺细胞及其表达的NT-3可能在其中起积极作用。 展开更多
关键词 牙周 神经末梢 牙齿移动 咬合 雪旺细胞 神经营养素-3
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The effect and safety of chronic total occlusion etrograded recanalization by epicardial collateral channel
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作者 周仪 钟志安 +3 位作者 黄泽涵 吴开泽 马墩亮 张斌 《岭南心血管病杂志:英文版》 CAS 2019年第1期37-43,共7页
Background Data on retrograde recanalization of epicardial collateral channels in patients with chronic total occlusion(CTO) undergoing percutaneous coronary intervention(PCI) are limited. Fearing about the complicati... Background Data on retrograde recanalization of epicardial collateral channels in patients with chronic total occlusion(CTO) undergoing percutaneous coronary intervention(PCI) are limited. Fearing about the complications of perforation, few CTO patients have chosen retrograde recanalization of epicardial collateral channels. Methods A retrospective analysis was conducted in this study. We followed up eligible patients who underwent continuous CTO via epicardial CCS from August 2011 to October 2018 in our center, and analyzed the detailed clinical baseline and angiographic data, surgical success rate and hospital complications to determine the efficacy and safety. The Cox model was used to compare major adverse cardiac events(MACE) and related co-variables between CTO patients with epicardial CCS perforation and non-perforated PCI patients. Results The study enrolled 191 patients with epicardial CCs PCI of CTO and the long term follow-up time was 24.03±19.18 months.Successful CCs PCI of CTO was achieved in 161(84.8 %) patients. Procedural collateral perforation occurred in23(12.0%) patients. MACEs occurred in 18 patients(9.4%) at 1-year follow-up. Kaplan-Meier curves showed no significant difference in MACEs between perforating recanalization of CCs PCI of CTO and non-perforating PCI of CTO.( adjusted hazard ratios(HR): 0.467;95% confidence intervals(CI): 0.13 to 1.69, P=0.245). The multivariate Cox regression analysis identified the Werner score=0/1(HR: 5.80;95% CI: 1.89 to 17.8;P=0.002) as significant independent predictors of perforation of CCs PCI of CTO. Conclusions The major complication of the procedure is collateral perforation. Recanalization of CTOs through epicardial collateral channel is safe and effective. It may be a available choice for recanalization of complex CTO. 展开更多
关键词 EPICARDIAL COLLATERAL CHANNEL chronic total occlusion COLLATERAL PERFORATION SAFETY and effective
遮挡图像分析及完形检测算法
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作者 莫丽莎 马惠敏 《电子测量与仪器学报》 CSCD 北大核心 2019年第4期10-18,共9页
针对复杂场景下现有的检测算法应对遮挡问题的鲁棒性不足的问题,建立了贯穿性截断遮挡模型及数据集、完成了遮挡对检测算法的影响分析且设计了一种抗遮挡目标检测算法。根据自然场景下的遮挡规律,提出了贯穿性截断遮挡模型来模拟真实遮... 针对复杂场景下现有的检测算法应对遮挡问题的鲁棒性不足的问题,建立了贯穿性截断遮挡模型及数据集、完成了遮挡对检测算法的影响分析且设计了一种抗遮挡目标检测算法。根据自然场景下的遮挡规律,提出了贯穿性截断遮挡模型来模拟真实遮挡;继而,以不同宽度、不同位置、不同朝向的灰条对无遮挡物体添加截断遮挡并建立了相应数据集,采用Fast R-CNN网络进行目标检测,并对检测结果完成可视化分析、IoU及其偏移量分析和候选区域遮挡前后MABO分数对比分析;依据分析实验结论和格式塔准则,设计提出了采取制定候选区域合并策略和设计基于一致性敏感哈希算法修复实现的抗遮挡目标检测算法框架。该框架的检测结果在建立的贯穿性截断遮挡数据集上与基线Fast R-CNN相比,平均准确率(mAP)取得了4.3%的提升。利用已知信息来推断被遮挡的未知信息建立的框架提升了目标检测算法应对遮挡现象的鲁棒性,对于遮挡干扰影响分析和抗遮挡检测算法的设计都具有重要指导意义。 展开更多
关键词 遮挡 目标检测 贯穿性截断遮挡 候选区域合并 粗糙修复
康柏西普联合光凝治疗视网膜分支静脉阻塞黄斑水肿
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作者 赵学军 张小鹏 张超玲 《中华眼外伤职业眼病杂志》 2019年第2期143-146,共4页
目的观察玻璃体内注射康柏西普联合光凝治疗缺血型视网膜分支静脉阻塞所致黄斑水肿的临床疗效。方法回顾性分析2014年6月至2018年4月在本院眼科缺血型视网膜分支静脉阻塞所致黄斑水肿48例(48眼)的临床资料,患者按住院顺序平均分为观察... 目的观察玻璃体内注射康柏西普联合光凝治疗缺血型视网膜分支静脉阻塞所致黄斑水肿的临床疗效。方法回顾性分析2014年6月至2018年4月在本院眼科缺血型视网膜分支静脉阻塞所致黄斑水肿48例(48眼)的临床资料,患者按住院顺序平均分为观察组和对照组,观察组行康柏西普联合视网膜激光光凝治疗,对照组直接行视网膜激光光凝治疗。观察两组治疗前及治疗后1周、1个月、3个月的最佳矫正视力、黄斑中心区视网膜厚度及并发症情况。结果观察组和对照组的视力和黄斑中心区视网膜厚度的差异在治疗后各时间点均有统计学意义(P<0.05)。结论玻璃体内注射康柏西普联合激光治疗缺血型视网膜分支静脉阻塞所致黄斑水肿可提高视力,减轻水肿,预防并发症的发生。 展开更多
关键词 阻塞 分支静脉 视网膜 水肿 黄斑 康柏西普 玻璃体内注射 光凝 激光
Treatment of upper and lower lacrimal punctal occlusion using retrograde canaliculotomy and punctoplasty
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作者 Ai Zhuang Jing Sun Wo-Dong Shi 《国际眼科杂志:英文版》 SCIE CAS 2019年第9期1498-1502,共5页
This is a retrospective, noncomparative analysis of a case series to explore the safety and effectiveness of retrograde canaliculotomy and punctoplasty for treating epiphora due to upper and lower lacrimal punctal occ... This is a retrospective, noncomparative analysis of a case series to explore the safety and effectiveness of retrograde canaliculotomy and punctoplasty for treating epiphora due to upper and lower lacrimal punctal occlusion. During the procedure, the horizontal portion of the normal lower canaliculus was identified;the corresponding punctum was reconstructed via retrograde canaliculotomy and punctoplasty. Intubation was performed to prevent postoperative reocclusion. Patients were followed up for 12 to 24 mo. A total of 16 patients with unilateral upper and lower lacrimal punctal occlusion were included. Satisfactory outcomes were achieved: all 16 patients exhibited improvement of epiphora;31 rebuilt punctal openings and canaliculi achieved recanalization. Only one upper punctal opening could not be reconstructed because the corresponding canaliculus exhibited severe injury. No significant complications occurred as a result of the treatments. Retrograde canaliculotomy and punctoplasty appears to effective, safe, and minimally invasive for treatment of upper and lower punctal occlusion. 展开更多
关键词 punctal OCCLUSION RETROGRADE canaliculotomy punctoplasty INTUBATION
椎动脉椎间段反向血流频谱在判断颈部血管病变部位中的应用价值 预览
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作者 吴治胜 唐琪 穆玉明 《广西医学》 CAS 2019年第15期1914-1916,共3页
目的探讨椎动脉间段反向血流频谱在判断颈部血管病变部位中的应用价值。方法83例明确诊断为椎动脉病变的患者,均行颈动脉彩色多普勒超声检查。所有患者椎动脉椎间段血流频谱呈反向。根据血管病变部位,将患者分为锁骨下动脉狭窄组61例和... 目的探讨椎动脉间段反向血流频谱在判断颈部血管病变部位中的应用价值。方法83例明确诊断为椎动脉病变的患者,均行颈动脉彩色多普勒超声检查。所有患者椎动脉椎间段血流频谱呈反向。根据血管病变部位,将患者分为锁骨下动脉狭窄组61例和椎动脉起始段闭塞组22例。观察患者椎动脉椎间段血流及频谱图像,比较两组患侧椎动脉血流速度及内径、对侧椎动脉血流频谱参数。结果锁骨下动脉狭窄组的患侧椎动脉椎间段血流频谱形态在收缩期及舒张期均表现为反向血流信号,椎动脉起始段闭塞组在收缩期表现为反向的低速血流信号,而在舒张期无血流信号。椎动脉起始段闭塞组患侧椎动脉收缩期及舒张期流速均慢于锁骨下动脉狭窄组(均P<0.05),两组对侧椎动脉血流频谱参数差异均无统计学意义(均P>0.05)。结论椎动脉椎间段反向血流频谱能够为快速寻找颈部血管病变部位提供重要线索。 展开更多
关键词 椎动脉 锁骨下动脉 颈部血管病变 狭窄 闭塞 内径 血流速度 椎间段 彩色多普勒超声 血流频谱 病变部位 诊断
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基于区域先验信息的去遮挡立体匹配算法
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作者 陈先锋 郭正华 +3 位作者 伍俊龙 马帅 杨平 许冰 《激光与光电子学进展》 CSCD 北大核心 2019年第19期87-93,共7页
提出了一种基于区域先验信息的去遮挡立体匹配算法。该方法采用边缘检测和区域生长对参考图像进行区域分割,将分割后的同质区域作为区域先验信息引入代价计算中,减弱了代价函数对遮挡区域的敏感度,并使用区域一致性检测修正遮挡和误匹... 提出了一种基于区域先验信息的去遮挡立体匹配算法。该方法采用边缘检测和区域生长对参考图像进行区域分割,将分割后的同质区域作为区域先验信息引入代价计算中,减弱了代价函数对遮挡区域的敏感度,并使用区域一致性检测修正遮挡和误匹配像素,从而获得精确视差图。所提算法是一种加性算法,在不显著增加计算量的同时,可有效提升算法对遮挡区域的匹配效果。使用Middlebury数据集进行测试,测试结果表明,所提算法能够有效降低遮挡区域的误匹配率。 展开更多
关键词 图像处理 遮挡 立体匹配 边缘检测 区域分割
Common iliac artery occlusion with small intestinal transection caused by blunt abdominal trauma:A case report and review of the literature 预览
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作者 You-Xin Zhou Yong Ji +3 位作者 Jing Chen Xin Yang Qing Zhou Jian Lv 《世界临床病例杂志》 2019年第15期2120-2127,共8页
BACKGROUND Most major abdominal vascular injuries are caused by penetrating injuries.A common iliac artery occlusion caused by blunt force trauma is rare,and very few cases have been reported.Because of this low incid... BACKGROUND Most major abdominal vascular injuries are caused by penetrating injuries.A common iliac artery occlusion caused by blunt force trauma is rare,and very few cases have been reported.Because of this low incidence,atypical symptoms,and frequent association with other severe injuries,the proper diagnosis tends to be missed or delayed.The gold standard for diagnosis is angiography,and treatment remains a challenge.CASE SUMMARY We report here the unusual case of a common iliac artery occlusion caused by blunt abdominal compressive trauma,with transection of the small intestine.At presentation,the patient(a 56-year-old man)complained of pain and numbness in the left lower extremity and severe pain in the whole abdomen.Physical examination showed total abdominal tenderness with evidence of peritoneal irritation.The left lower limb was pulseless and cold.Abdominal computed tomography examination revealed digestive tract perforation,and abdominal computed tomography angiography showed left common iliac artery occlusion.The patient was treated successfully by anastomosis of the intestine,percutaneous transluminal angioplasty,and stenting.The patient was followed for more than 11 mo after the operation and showed a good recovery.CONCLUSION Patients with abdominal trauma should be suspected of having major vascular injury.Individualized treatment strategies are needed for this condition. 展开更多
关键词 Common ILIAC artery OCCLUSION TRANSECTION of the small INTESTINE BLUNT abdominal trauma Case report Percutaneous TRANSLUMINAL angioplasty Anastomosis of the INTESTINE
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慢性脑动脉闭塞供血区脑皮层灰质及深部白质的血流CT灌注分析
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作者 安盼盼 师红美 +5 位作者 任庆国 张冠经 任国荣 管帅 张晓倩 孟祥水 《中华放射学杂志》 CAS CSCD 北大核心 2019年第10期877-881,共5页
目的探讨慢性脑动脉重度狭窄或闭塞致脑皮层灰质及深部脑白质的不同缺血特征。方法回顾性收集山东大学齐鲁医院2014年4月至2018年4月单侧脑动脉重度狭窄或闭塞且常规影像检查脑组织无责任梗塞灶患者30例,行CTP检查,测量责任动脉供血区(... 目的探讨慢性脑动脉重度狭窄或闭塞致脑皮层灰质及深部脑白质的不同缺血特征。方法回顾性收集山东大学齐鲁医院2014年4月至2018年4月单侧脑动脉重度狭窄或闭塞且常规影像检查脑组织无责任梗塞灶患者30例,行CTP检查,测量责任动脉供血区(患侧)及对侧大脑半球(健侧)脑皮层灰质、深部脑白质脑血流量(CBF)、脑血容量(CBV)、平均通过时间(MTT)、达峰时间(TTP)及排出时间(TTD)值,患侧与健侧脑皮层灰质及深部脑白质灌注参数值进行组间比较,方差齐采用t检验,方差不齐采用t′检验。结果患侧及健侧脑皮层灰质CBF、CBV平均值均大于同侧深部脑白质(P<0.01),患侧及健侧脑皮层灰质MTT、TTP、TTD平均值均小于同侧深部脑白质(P<0.01);患侧脑皮层灰质CBF平均值与健侧比较差异无统计学意义,患侧深部脑白质CBF平均值较健侧减小(P<0.01);患侧脑皮层灰质CBV平均值较健侧增大(P<0.01),深部脑白质CBV平均值较健侧差异无统计学意义;患侧脑皮层灰质及深部脑白质MTT、TTP、TTD平均值均较健侧相应区域延长(P<0.01)。结论慢性重度狭窄或闭塞脑动脉供血区深部脑白质灌注减低较皮层灰质明显,CTP能够对慢性脑缺血程度量化评价,为临床治疗及疗效评估提供定量诊断依据。 展开更多
关键词 脑动脉 体层摄影术 X线计算机 狭窄 闭塞
加权颜色粒子滤波与SIFT特征双融合的行人跟踪 预览
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作者 魏旭东 秦立峰 《计算机工程与设计》 北大核心 2019年第2期556-561,共6页
为改善粒子退化现象,提高粒子滤波算法对于遮挡目标的跟踪精度,提出加权颜色特征与SIFT特征双层融合的粒子滤波算法。用粒子的位置信息对传统粒子权重进行改进,作为内层融合,对SIFT点匹配跟踪框与粒子滤波跟踪框进行外融合,改善遮挡情... 为改善粒子退化现象,提高粒子滤波算法对于遮挡目标的跟踪精度,提出加权颜色特征与SIFT特征双层融合的粒子滤波算法。用粒子的位置信息对传统粒子权重进行改进,作为内层融合,对SIFT点匹配跟踪框与粒子滤波跟踪框进行外融合,改善遮挡情况下粒子退化的情况,提高跟踪精度。在VOT2014视频数据库上的实验结果表明,提出算法平均跟踪精度为95.03%,较传统粒子滤波算法提高了6个百分点。 展开更多
关键词 目标跟踪 遮挡 粒子滤波 SIFT点 算法融合 粒子退化
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Intravascular ultrasound-guided “extended” reverse controlled antegrade and retrograde subintimal tracking technique using a cutting balloon for recanalizing chronic coronary total occlusion with a side branch 预览
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作者 Yong-Tai GONG Jian-Qiang LI +2 位作者 Li SHENG Dang-Hui SUN Yue LI 《老年心脏病学杂志:英文版》 SCIE CAS CSCD 2019年第6期498-501,共4页
Percutaneous coronary intervention (PCI) of chronic total occlusion (CTO) represents the most technically challenging procedure in contemporary interventional cardiology.[1] Blunt lesions and presence of proximal side... Percutaneous coronary intervention (PCI) of chronic total occlusion (CTO) represents the most technically challenging procedure in contemporary interventional cardiology.[1] Blunt lesions and presence of proximal side branch are considered to be strong predictors of reduced technical success.[ 2,3] For such lesions, the antegrade approach may not be feasible or desirable, and the retrograde approach can be used as the initial crossing strategy. However, when treating the blunt CTO with a large side branch proximal to the occlusion, the side branch might be occluded after stent implantation if the retrograde guidewire passed the occluded segment through the subintimal space and re-entered into the true lumen at the opposite side of the side branch.[4] We reported a useful method to solve the above issue which utilizes intravascular ultrasound (IVUS) to guide “extended” reverse controlled antegrade and retrograde subintimal tracking (CART) technique with a cutting balloon. 展开更多
关键词 Chronic total OCCLUSION Cutting balloon INTRAVASCULAR ultrasound Percutaneous CORONARY intervention REVERSE controlled ANTEGRADE and RETROGRADE tracking technique
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Successful opening in-stent chronic total occlusion lesion of coronary artery by excimer laser coronary angioplasty 预览
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作者 Jing BAI Hai-Xia WANG +7 位作者 Jiang-Tao WANG Jing ZHAO Liang PENG Xue-Dong YANG Zhe TANG Shaheena Nazneen Gao-Kun WANG Yu WANG 《老年心脏病学杂志:英文版》 SCIE CAS CSCD 2019年第6期502-506,共5页
In percutaneous coronary intervention (PCI), chronic total occlusion (CTO) coronary artery disease still remains difficult to treat. One of the reasons for the failure is the hard of the CTO lesions that balloon is di... In percutaneous coronary intervention (PCI), chronic total occlusion (CTO) coronary artery disease still remains difficult to treat. One of the reasons for the failure is the hard of the CTO lesions that balloon is difficult to pass through or expand. Previous methods to deal with CTO lesions that cannot be passed by balloon, include selecting reinforced catheter (such as 5 in 6 guiding catheter, Guidzilla catheter, or Tornus microcatheter), guidewire extrusion or rotary grinding technology. In recent years, excimer laser coronary angioplasty (ELCA) has been gradually applied to CTO lesions. Using inert halide as the laser medium, ELCA emits a 308 nm high-intensity unidirectional light wave with absorption depth of only 50 μmL, resulting in less thermal effect and less damage to non-target lesions. In this paper, we will describe a successful PCI case of an in-stent CTO lesion using ELCA with long term coronary angiography follow-up. 展开更多
关键词 Chronic total OCCLUSION Drug coating BALLOON EXCIMER laser CORONARY ANGIOPLASTY Percutaneous CORONARY intervention
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症状性颅外段椎动脉长节段闭塞复合手术一例 预览
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作者 杨斌 马妍 焦力群 《中国脑血管病杂志》 CAS CSCD 北大核心 2019年第1期36-38,52共4页
回顾性分析1例症状性颅外段椎动脉长节段闭塞且规范药物治疗期间仍有反复后循环缺血发作患者的临床及影像学资料,探讨复合手术治疗症状性颅外段椎动脉长节段闭塞的优势。患者为72岁男性,主要临床表现为发作性眩晕伴行走不稳。既往MRI检... 回顾性分析1例症状性颅外段椎动脉长节段闭塞且规范药物治疗期间仍有反复后循环缺血发作患者的临床及影像学资料,探讨复合手术治疗症状性颅外段椎动脉长节段闭塞的优势。患者为72岁男性,主要临床表现为发作性眩晕伴行走不稳。既往MRI检查示双侧小脑急性脑梗死,规范药物治疗期间仍有后循环缺血反复发作。本次入院DSA示右侧椎动脉V1至V2段闭塞,甲状颈干分支通过肌支血管代偿V2段及以远椎动脉血供,左侧椎动脉末端纤细;MRI无创优化血管分析提示右侧椎动脉V3段及基底动脉血流量明显低于正常值下限。患者于全身麻醉下接受右侧椎动脉闭塞复合再通术治疗后椎动脉再通,后循环血流改善。18个月随访期间血流通畅,症状无复发。结合文献复习认为对于药物治疗无效的症状性颅外段椎动脉长节段闭塞而言,复合手术结合了手术和介入的优势而能取得更优的治疗效果,可能是安全有效的治疗方式。 展开更多
关键词 椎动脉 闭塞 症状性 复合手术
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