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中医药治疗臁疮研究进展 认领
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作者 于洋 王景 +3 位作者 郭伟光 张海丽 滕林 回雪颖 《辽宁中医药大学学报》 CAS 2020年第2期147-149,共3页
臁疮是临床较难治愈的疾病之一,危害患者的健康。西医治疗主要采用手术疗法,创口不易愈合导致病情反复。近几年中医药治疗臁疮取得显著的疗效,臁疮的中医病因病机为气血亏虚日久、气滞血瘀、经络痹阻、湿热下注、局部皮肤失于濡养、湿... 臁疮是临床较难治愈的疾病之一,危害患者的健康。西医治疗主要采用手术疗法,创口不易愈合导致病情反复。近几年中医药治疗臁疮取得显著的疗效,臁疮的中医病因病机为气血亏虚日久、气滞血瘀、经络痹阻、湿热下注、局部皮肤失于濡养、湿毒侵淫发而为病。中医药治疗主要是以中医基础理论为指导的内治和外治疗法,尤以外治法多见疗效也最为显著。但因其病程较久疾病的难治愈性,多种治疗方法并用从而更能发挥中医药的优势。文章综述了近10年中医药治疗臁疮取得的成果,以期为中医临床及科研工作者提供一定的理论参考。 展开更多
关键词 臁疮 中医药 病因病机 内治法 外治法 辨证论治
Using ultrasound to improve the sequential post-synthesis modification method for making mesoporous Y zeolites 认领
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作者 Rongxin Zhang Peinan Zhong +5 位作者 Hamidreza Arandivan Yanan Guan Jinmin Liu Na Wang Yilai Jiao Xiaolei Fan 《化学科学与工程前沿:英文版》 SCIE EI CAS CSCD 2020年第2期275-287,共13页
Mesoporous Y zeolites were prepared by the sequential chemical dealumination(using chelating agents such as ethylenediaminetetraacetic acid,H EDTA,and citric acid aqueous solutions)and alkaline desilication(using sodi... Mesoporous Y zeolites were prepared by the sequential chemical dealumination(using chelating agents such as ethylenediaminetetraacetic acid,H EDTA,and citric acid aqueous solutions)and alkaline desilication(using sodium hydroxide,NaOH,aqueous solutions)treatments.Specifically,the ultrasound-assisted alkaline treatment(i.e.,ultrasonic treatment)was proposed as the alternative to conventional alkaline treatments which are performed under hydrothermal conditions.In comparison with the hydrothermal alkaline treatment,the ultrasonic treatment showed the comparatively enhanced efficiency(with the reduced treatment time,i.e.,5 min vs.30 min,all with 0.2 mol·L NaOH at 65°C)in treating the dealuminated Y zeolites for creating mesoporosity.For example,after the treatment of a dealuminated zeolite Y(using 0.1 mol·L H EDTA at 100°C for 6 h),the ultrasonic treatment produced the mesoporous zeolite Y with the specific external surface area()of 160 m·g and mesopore volume()of 0.22 cm·g,being slightly higher than that by the conventional method(i.e.,=128 m·g and=0.19 cm·g).The acidic property and catalytic activity(in catalytic cracking of-octane)of mesoporous Y zeolites obtained by the two methods were comparable.The ultrasonic desilication treatment was found to be generic,also being effective to treat the dealuminated Y zeolites by citric acid.Additionally,the first step of chemical dealumination treatment was crucial to enable the effective creation of mesopores in the parent Y zeolite(with a silicon-to-aluminium ratio,Si/Al=2.6)regardless of the subsequent alkaline desilication treatment(i.e.,ultrasonic or hydrothermal).Therefore,appropriate selection of the condition of the chemical dealumination treatment based on the property of parent zeolites,such as Si/Al ratio and crystallinity,is important for making mesoporous zeolites effectively. 展开更多
关键词 zeolite Y mesoporous zeolite post-synthesis treatment ULTRASOUND chemical dealumination treatment alkaline desilication treatment
Adoption of Artificial Intelligence for Diagnosis and Treatment of <i>Staphylococcus aureus</i>Infections Disease on Humans 认领
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作者 Kanayo Kizito Uka Stanley Ikechukwu Oguoma +1 位作者 Chekwube Alphonsus Chukwu Chijioke Izuchukwu Emele 《远程医疗系统和网络(英文)》 2020年第1期1-15,共15页
The aim of this paper is to develop an expert system that could aid medical practitioner to effectively diagnose and treat Staphylococcus aureus infections disease on a human. The objective of the research includes to... The aim of this paper is to develop an expert system that could aid medical practitioner to effectively diagnose and treat Staphylococcus aureus infections disease on a human. The objective of the research includes to develop an expert system for quick diagnosis and detection of Staphylococcus aureus bacteria on human skin, a system that aids in accurate treatment of staph infectious diseases by doctors, helps in quick decision making in the hospital, improves accuracy in drug prescription, and a system that will bring about computerized storage process, and to enlighten the knowledge workers on how to implement a computer based decision support systems and importance of it in the health care. The research was motivated due to delay in diagnosis and identification of Staphylococcus aureus bacteria and the fast rate at which infectious disease is spreading, delay in treatment of these bacteria, increase of guess work by health practitioners leading to delay in decision making and lack of electronic storage facility in the hospitals. Top down approach was used in the system design of this research while adopting expert system as the methodology and the programming language used was Java and database design used was MySQL. The result after design was a computerized standalone application that assists health practitioners (Doctor’s) in quick identification, diagnosis, prescription and treatment of Staphylococcus aureus bacteria on human skin. The expert system will facilitate quick decision making in the clinic. 展开更多
关键词 Artificial Intelligence Expert System Diagnosis Treatment STAPHYLOCOCCUS AUREUS INFECTIOUS Disease
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Management of Subtalar Fractures-Dislocations at Ségou Hospital in Mali: A 7 Cases Series 认领
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作者 Mahamadou Diallo Abdoul Kadri Moussa +8 位作者 Layes Toure Louis Traoré Cheick Oumar Sanogo Terna Traore Seydina Alioune Beye Abdrahamane Toure Making Mounkoro Mahamadou Kane Tiéman Coulibaly 《外科学(英文)》 2020年第4期51-60,共10页
Introduction: Subtalar or peritalian dislocation is rare;it represents 15% of peritalian injuries. The aim of this study was to describe the radioclinical and therapeutic characteristics and to assess the functional r... Introduction: Subtalar or peritalian dislocation is rare;it represents 15% of peritalian injuries. The aim of this study was to describe the radioclinical and therapeutic characteristics and to assess the functional result. Patients and Methods: This study is about a continuous descriptive and prospective study over a period of 5 years. It has been conducted from March 2013 to February 2018 at the Ségou Hospital, a second referral hospital in Mali. The functional results were evaluated by the score of the American Orthopedic Foot and Ankle Society (AOFAS). Results: Seven cases of subtalar dislocation fractures were diagnosed in six male patients with an average age of 38 years (36 to 47 years old). In five cases the etiology of the trauma was a motorcycle accident and a fall from height. The lesion was bilateral in one case. The average time to care was 3 hours (1 to 9 hours). There was one case of open dislocation fracture with talus enucleation. The dislocation was medial in 6 cases and lateral in one case. It was pure in three cases. The treatment was orthopedic in 2 cases and surgical in 5 cases. The post-operative complications were complicated by an infection of the operative site in one case. The average length of hospital stay was 4 days. The functional result was excellent in 2 cases;good in 2 cases, fair in 2 cases and poor for 1 case. Conclusion: Subtalar dislocation is a rare and serious lesion of the posterior tarsus. The long-term prognosis depends on the earliness of treatment and the severity of the associated injuries. 展开更多
关键词 FRACTURE DISLOCATION SUBTALAR PROGNOSIS Treatment
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The Epidemiology of Acne Vulgaris among Adolescents and Young Adults in Jordan University Hospital 认领
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作者 Ruba M. Jaber Basma M. Alnshash +3 位作者 Suzan N. Mousa Hanan S. Fayoumi Lana M. Al-Qaderi Asma M. Zant 《护理学期刊(英文)》 2020年第4期353-366,共14页
Background: Acne vulgaris is a widely prevalent distressing problem among young adults and adolescents. Almost one-third of young people consider acne to be a major problem/burden. Less than half of acne diagnoses are... Background: Acne vulgaris is a widely prevalent distressing problem among young adults and adolescents. Almost one-third of young people consider acne to be a major problem/burden. Less than half of acne diagnoses are made by a physician, and acne is often self-managed. Objective: We aim to find the prevalence of acne among different age groups, treatment seeking behaviors and sources of knowledge about acne treatment. We also aim to determine impact of acne vulgaris on quality of life and psychology of patients. Design: A cross-sectional study. Setting: Jordan university hospital, Amman, Jordan. Subjects: Patients aged 15 - 35 years old who attended the family medicine clinic in Jordan University Hospital. Intervention: A self-administered questionnaire, consisted of three major parts, distributed during the period between August 2019 and October 2019. Results: Upon analyzing the data, 153 out of the 300 participants were found to have suffered or were still suffering from acne with a prevalence of 45%. The mean age at which the acne started was 16.20. There was a significant correlation between severity of acne and impact on life. More than half of the affected participants sought doctor help to treat their acne;patients depended on many sources of information to manage their acne. The majority of them reported the dermatologist as their source of information. Patients tended to use different methods of treatment to manage their acne. The cleanser was the most commonly used methods of treatment. Conclusion: Our article demonstrates that acne is a prevalent distressing problem among adolescents;it affects patients’ quality of life. Different modalities of treatment and sources of information were sought by patients. As family doctors, we emphasize the need for accessible, accurate, community-based education on the modalities of treatment of acne, and the importance of prompt medical attention toward its effect on quality of life. 展开更多
关键词 ACNE VULGARIS Prevalence Quality of Life Treatment Adolescents CYST Whiteheads Blackheads NODULES
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Surgical treatment of Lipodermoids - Case Report 认领
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作者 Shoshi Flaka Hoxha-Shoshi Mire +2 位作者 Shoshi Fitore Shoshi Fjolla Shoshi Avdyl 《眼科学期刊(英文)》 2020年第1期1-9,共9页
Lipodermoids are abnormal epibulbar growths of the adipose tissue. A conjunctival lesion, the lipodermoid (dermolipoma) is usually located near the temporal fornix and is composed of adipose tissue and dense connectiv... Lipodermoids are abnormal epibulbar growths of the adipose tissue. A conjunctival lesion, the lipodermoid (dermolipoma) is usually located near the temporal fornix and is composed of adipose tissue and dense connective tissue. The overlying conjunctival epithelium is normal, and hair follicles are absent. Lipodermoids may be extensive, sometimes involving orbital tissue, lacrimal gland, and extraocular muscle. Surgical treatment is only indicated when the existing lipodermoid disturbs the patient either functionally or aesthetically. Purpose The main purpose of this study is to present our experience on the surgical treatment of lipodermoids in those cases when lipodermoids cause functional and aesthetic problem to the patient. Materials and Methods In our study we have included two cases of male gender, one with bilateral lipodermoid (in both eyes) while the other with a mono lateral lipodermoid (only in one eye). The treatment was surgical, where we carefully removed the lipodermoid lesion inside palpebral fissures, to fully preserve the bulbar conjunctiva and Tenon’s membrane during the removal of the conjunctival lipodermoid.Surgery was performed under local anesthesia (lidocaine 2% and adrenaline). The surgical area was set ready by using betadine 5%. Results In both cases there were neither intra-operative nor extra-operative complications and the results were positive.Also the functional and aesthetic problems were corrected. There was no recurrence encountered.Conclusions In conclusion, based on the results of this study, in the rare cases of lipodermoids where surgical treatment is necessary, it is very important to perform a careful surgical intervention, in order to prevent any intra-operative injuries of the lacrimal gland and the lateral and superior rectus muscles. In general the surgical treatment is a successful method on treating lipodermoids, in cases when they concern the patient both functionally and aesthetically. 展开更多
关键词 Lipodermoids INTRA-OPERATIVE INJURIES TREATMENT
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The Long-Term Clinical Efficacy of Smart Plug in the Treatment of Aqueous Tear Deficiency Dry Eye: Results of a 5-Year Study 认领
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作者 Zhaoxia Kuang Yong Yao +6 位作者 Ye Yuan Yueting Ma Guanglin Chen Yingying Su Xingkai Zhang Vishal Jhanji Dennis Lam 《眼科学期刊(英文)》 2020年第1期21-27,共7页
Background: Dry eye syndrome, which affects 10% to 20% of adults, is a disorder of the tear film and is associated with symptoms of ocular discomfort. Smart Plug is a mechanical treatment in which the tear drainage sy... Background: Dry eye syndrome, which affects 10% to 20% of adults, is a disorder of the tear film and is associated with symptoms of ocular discomfort. Smart Plug is a mechanical treatment in which the tear drainage system is blocked in order to aid in the preservation of natural tears on the ocular surface. Purpose: To evaluate the long-term clinical efficacy of Smart Plug in the treatment of aqueous tear deficiency dry eye. Patients and Methods: Retrospective study. Three hundred and two patients with aqueous tear deficiency dry eye were enrolled and all the patients accepted the punctual plug of Smart plug from Jan. 2011 to Jan. 2016. The clinical symptoms, Schirmer’s I test, Fluorescein staining (FL), tear break up time (TBUT), and complications were observed and analyzed. Results: Three hundred and two patients (604 eyes) were treated with Smart Plug (22 cases accepted upper and lower punctual plug, 280 cases only lower punctual plug). There were 109 males (36.1%) and 193 females (63.9%) with a mean age of 44.54 years old (Range from 25 to 83 years). Ten cases required the upper Smart Plug after lower punctual plug insertion because of no significantly improved symptoms. Smart plug was removed in 3 patients (1%) due to tearing. Six patients had mild postoperative tearing and no special treatment was required. Lacrimal canaliculitis occurred postoperatively in 8 cases (2.6%) (6 lower and 2 upper), and the affected plug was removed and treated with topical antibiotic eye drops. The BUT, SIT and FL scores of all patients were significantly improved from (2.11 ± 1.01, 4.20 ± 1.07, 6.06 ± 1.97) to (4.34 ± 1.22, 9.01 ± 1.56, 2.33 ± 1.28) respectively after at least 36 months of follow-up (All P P Conclusion: During a mean follow-up of 4.3 years, Smart plug is an effective method for the treatment of aqueous tear deficiency dry eye in spite of its postoperative complications such as canaliculitis and tearing. 展开更多
关键词 LACRIMAL Dry Eye TREATMENT Smart-Plug Punctual PLUG
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Calyceal Diverticula and Megacalycosis Urographic Diagnosis Complications and Treatment 认领
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作者 Saleh Ahmed Akares Ahmed Awad Bahomil Ali Mothanna Al-Zubaidi 《泌尿学期刊(英文)》 2020年第5期167-175,共9页
Background: Calyceal diverticulae and megacalycosis are rare congenital anomalies. The majorities are asymptomatic but they can present with complications. Objective: The objective of this study is to describe the cli... Background: Calyceal diverticulae and megacalycosis are rare congenital anomalies. The majorities are asymptomatic but they can present with complications. Objective: The objective of this study is to describe the clinical presentations, complications, urographic diagnosis of calyceal diverticulae, megacalycosis, and their treatment. Methods: A descriptive study carried out over 8 years period from March 2012 to December 2019. In three big hospital of Aden province, we collect 15 patients aged from seven to 41 years (mean 13.5 years), our patients were 9 female (60%) and 6 male (40%). They diagnosed incidentally with calyceal diverticulae and megacalycosis by contrasted urography, describing the clinical manifestations, localization, complications, and type of treatment. Results: Sixty percent of patients with calyceal diverticulae and megacalycosis were women and (40%) were men. Clinical manifestations including, dull aching flank and abdominal pain in (40%), acute renal colic (20%), recurrent urinary tract infection (33%), and abdominal pain with a fever of unknown origin in (7%). Calyceal diverticula and megacalycosis were bilateral in (53%) and unilateral in (47%). In the right kidney were (57%), and in the left kidney (43%). In the upper pole of the kidney were (53.3%), middle pole (33.3%), and lower pole (13.3%). Complications occurred in (47%) of patients. They including, urinary stones in (71.4%), hypertension (14.3%), and delayed renal excretion (14.3%). Conservative treatment carried out in (73%) and surgically intervened in (27%). Conclusions: Calyceal diverticula and megacalycosis are rare anomalies. Dull aching flank pain and recurrent urinary tract infections are the most frequent clinical presentations. The most common complications are urinary stones. Conservative treatment is a common type of treatment. 展开更多
关键词 Calyceal Diverticulae and Megacalycosis DIAGNOSIS TREATMENT
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行为激活疗法在抑郁症治疗中的研究进展 认领
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作者 廖国栋 孙仁权 +4 位作者 蒙雪芳 蓝超越 黄大海 莫东波 苏艳飞 《中国卫生标准管理》 2020年第7期48-50,共3页
综述抑郁症患者防治的方式和效果,当前抑郁症疾病的防治也会逐渐成为心理精神科学研究过程中关注的主要内容,认知行为疗法在治疗的时候,主要是在人体的思维及行为等方面改变的基础上有效纠正人们所具备的不良认知,从而有效消除个人的不... 综述抑郁症患者防治的方式和效果,当前抑郁症疾病的防治也会逐渐成为心理精神科学研究过程中关注的主要内容,认知行为疗法在治疗的时候,主要是在人体的思维及行为等方面改变的基础上有效纠正人们所具备的不良认知,从而有效消除个人的不良情绪和不良行为的积极的治疗方式。行为激活疗法在抑郁症治疗中应用的时候,其具备自身的应用优势,但是这一治疗方式的具体实践要求比较高,在推广应用方面明显不足,而行为激活疗法是第3代认知疗法,行为激活疗法在具体应用的时候,对于抑郁症患者治疗具有操作简单和易推广等优势,这一方式的研究综述对之后抑郁症患者认知行为干预的研究提供参考。 展开更多
关键词 行为激活疗法 抑郁症 治疗 研究 进展 防治
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Odontogenic Cervico-Facial Cellulitis at the University Hospital of Brazzaville: About 431 Cases 认领
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作者 Eboungabeka Trigo Edith Rose Marcelle Dibansa Olivier Lekesse Chanelle 《口腔学期刊(英文)》 2020年第2期19-27,共9页
Context and Objective: Cellulitis is potentially serious polymicrobial infections that can be life-threatening for the patient. They are clearly increasing in our service. It is with the aim of determining the hospita... Context and Objective: Cellulitis is potentially serious polymicrobial infections that can be life-threatening for the patient. They are clearly increasing in our service. It is with the aim of determining the hospital frequency of cellulitis of dental origin epidemiological profile, describing the clinical types, the therapeutic modalities and evaluating the results obtained. Subjects and Methods: This is a retrospective descriptive study on the files of 431 hospitalized patients, between January 2010 and December 2018 in the department of stomatology and maxillofacial surgery of the University Hospital of Brazzaville (Congo). The studied parameters: The frequency, the age, the gender, the origin, the consultation average time, the contributing factors, the entrance gate, the seat, the paraclinical assessment, the therapeutic modalities and the evolution. Results: Cervico-facial cellulitis accounted for 32.8% of hospitalizations. The average age was 32.8 ± 1.98 years, ranges from 3 to 93 years. The predominance was male with 241 cases, or 55.9%. 64.73% of patients came from CHUB emergencies. The mandibular seat was dominant with 77.72% of cases. The average consultation time was 6 days. As a contributing factor, we found the consumption of nonsteroidal anti-inflammatory drugs (NSAIDs). Tooth decay was the most common etiology 92.5%. Antibiotic therapy and surgery had a good evolution in 96.8% of cases. The mortality rate was 3.3%. Conclusion: odontogenic cervicofacial cellulitis remains common in daily practice. Patient care should focus on the preventive component integrating patient awareness of oral health. 展开更多
关键词 Cervico-Facial CELLULITIS EPIDEMIOLOGY Clinical Treatment
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Management of complicated acute appendicitis in children:Still an existing controversy 认领
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作者 Nick Zavras George Vaos 《世界胃肠外科杂志:英文版(电子版)》 2020年第4期129-137,共9页
Complicated acute appendicitis(CAA)is a serious condition and carries significant morbidity in children.A strict diagnosis is challenging,as there are many lesions that mimic CAA.The management of CAA is still controv... Complicated acute appendicitis(CAA)is a serious condition and carries significant morbidity in children.A strict diagnosis is challenging,as there are many lesions that mimic CAA.The management of CAA is still controversial.There are two options for treatment:Immediate operative management and nonoperative management with antibiotics and/or drainage of any abscess or phlegmon.Each method of treatment has advantages and disadvantages.Operative management may be difficult due to the presence of inflamed tissues and may lead to detrimental events.In many cases,non-operative management with or without drainage and interval appendectomy is advised.The reasons for this approach include new medications and policies for the use of antibiotic therapy.Furthermore,advances in radiological interventions may overcome difficulties such as diagnosing and managing the complications of CAA without any surgeries.However,questions have been raised about the risk of recurrence,prolonged use of antibiotics,lengthened hospital stay and delay in returning to daily activities.Moreover,the need for interval appendectomy is currently under debate because of the low risk of recurrence.Due to the paucity of high-quality studies,more randomized controlled trials to determine the precise management strategy are needed.This review aims to study the current data on operative vs non-operative management for CAA in children and to extract any useful information from the literature. 展开更多
关键词 Complicated acute appendicitis Operative treatment Non-operative treatment ANTIBIOTICS CHILDREN
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A Study on the Biocompatibility of MgO Coating Prepared by Anodic Oxidation Method on Magnesium Metal 认领
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作者 Yangmei Chen Xugang Lu +5 位作者 Fenghua Zhao Yi Hu Shibing Xiong Yuqiang Guo Ping Huang Bangcheng Yang 《仿生工程学报:英文版》 SCIE EI CSCD 2020年第1期76-91,共16页
Magnesium(Mg),is widely used for the bone repair in oral and orthopedic application due to excellent bioactivity,degradation and biocompatibility.However,the range of application is greatly limited because of the rapi... Magnesium(Mg),is widely used for the bone repair in oral and orthopedic application due to excellent bioactivity,degradation and biocompatibility.However,the range of application is greatly limited because of the rapid degradation of Mg metal in the body.Surface modification is an effective method to enhance the corrosion resistance and reduce the degradation rate of Mg metal.In the present study,pure Mg metal(P-Mg)was subjected to alkali-heat treatment(AT-Mg)or anodic oxidation-heat treatment(AO-HT-Mg).Both AT-Mg and AO-HT-Mg had a layer of MgO on their surfaces after treatment.Then the effects of MgO coating on corrosion resistance,bioactivity,Mesenchymal Stem Cells’(MSCs)proliferation,adhesion and osteogenic differentiation,and the bone repair capability of Mg metal were investigated.We found both AT-Mg and AO-HT-Mg had stronger corrosion resistance than P-Mg.MSCs on both AT-Mg and AO-HT-Mg had higher expression of proteins and genes of ALP,OCN,Col-I and Runx2 than those on P-Mg.They also showed better bone repair property than P-Mg in vivo.In general,MgO layer formed by anodic oxidation-heat treatment had better resistance and biocompatibility than that produced by alkali-heat treatment.This study indicated the MgO coating not only improved the corrosion resistance of Mg metal,but also promoted the osteogenic differentiation of MSCs and bone regeneration. 展开更多
关键词 MAGNESIUM MgO coating alkali-heat treatment anodic oxidation-heat treatment corrosion resistance biomedical-materials
Hip Joint Osteoarthritis Pain Sources and Control 认领
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作者 Ray Marks 《疼痛研究与治疗(英文)》 2020年第1期1-21,共21页
Hip joint osteoarthritis, a widespread disabling disease with no known cause, produces considerable bouts of intractable pain as a result of multiple disease associated problems. This paper examines some sources of os... Hip joint osteoarthritis, a widespread disabling disease with no known cause, produces considerable bouts of intractable pain as a result of multiple disease associated problems. This paper examines some sources of osteoarthritic hip joint pain, a poorly understood topic at best. Presented in three parts are data retrieved from several sources, including animal models. It is concluded that to improve the effectiveness of treatments designed to minimize hip osteoarthritis pain, a better understanding of the diverse origins of hip joint pain, and hip joint neurology, may permit the development of more precise as well as targeted pain strategies. 展开更多
关键词 HIP Joint INNERVATION Muscles NERVES OSTEOARTHRITIS PAIN Prevention Treatment
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A review of traditional Chinese medicine in the treatment of alzheimer's disease 认领
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作者 Ke-Qing Dong 《衰老研究》 2020年第1期11-16,共6页
A systematic review and summary of the methods of traditional Chinese medicine for the treatment of Alzheimer's disease,and a preliminary discussion of its mechanism of action,in order to provide ideas and ways fo... A systematic review and summary of the methods of traditional Chinese medicine for the treatment of Alzheimer's disease,and a preliminary discussion of its mechanism of action,in order to provide ideas and ways for further scientific clinical summary and mechanism exploration. 展开更多
关键词 Alzheimer's DISEASE TCM TREATMENT ACUPUNCTURE TREATMENT
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Treatment satisfaction with rheumatoid arthritis in patients with different disease severity and financial burden: A subgroup analysis of a nationwide survey in China 认领
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作者 Hong-Bin Li Li-Jun Wu +13 位作者 Nan Jiang Ping-Ting Yang Sheng-Yun Liu Xiao-Fei Shi Yong-Fei Fang Yi Zhao Jian Xu Zhen-Yu Jiang Zhen-Biao Wu Xin-Wang Duan Qian Wang Meng-Tao Li Xin-Ping Tian Xiao-Feng Zeng 《中华医学杂志:英文版》 SCIE CAS CSCD 2020年第8期892-898,共7页
Background::Despite the recent advances in treatments for rheumatoid arthritis (RA), there are still unmet needs in disease outcomes. This study aimed to analyze the satisfaction with drug therapies for RA according t... Background::Despite the recent advances in treatments for rheumatoid arthritis (RA), there are still unmet needs in disease outcomes. This study aimed to analyze the satisfaction with drug therapies for RA according to the levels of disease severity (patientassessed) and proportions of treatment cost to household income.Methods::This was a subgroup study of a cross-sectional study in patients with RA and their physicians. The patients were subdivided into different subgroups based on their self-assessed severity of RA and on the proportions of treatment cost to household income (<10%, 10-30%, 31-50%, and >50%). The Treatment Satisfaction Questionnaire for Medication version II was used to assess patients’ treatment satisfaction.Results::When considering all medications, effectiveness, convenience, and global satisfaction scores were lower in the severe and moderate RA subgroups than those in the mild and extremely mild RA subgroups (all P < 0.001). Effectiveness, side effects, and convenience scores were higher in the <10% subgroup compared to those in the >50% subgroup (all P < 0.05). Global satisfaction score was higher in the <10% subgroup than that in the 31% to 50% subgroup ( F = 13.183, P = 0.004). For biological diseasemodifying anti-rheumatic drugs, effectiveness and convenience scores were lower in the severe RA subgroup than those in the extremely mild RA subgroup (both P < 0.05). Convenience score was higher in the <10% subgroup compared to that in the 31% to 50% and >50% subgroups ( F = 12.646, P = 0.005). Global satisfaction score was higher in the <10% subgroup than that in the 31% to 50% subgroup ( F = 8.794, P = 0.032). Conclusion::Higher disease severity and higher financial burden were associated with lower patient satisfaction. 展开更多
关键词 Disease severity Rheumatoid arthritis Treatment cost Treatment satisfaction
电厂化学水处理设备设施腐蚀问题和处理方法 认领
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作者 王勇 杨林 杨学荣 《化工设计通讯》 CAS 2020年第1期101-102,共2页
随着当前社会经济的不断发展与提升,人们对电力的要求也变的越来越大。对此,如果想要满足当前人们的电力需要,那么就需要在一定的程度上加强电厂的工作效率。但是,在当前的情况下,电厂存在着化学水处理设备设施腐蚀的问题,这些问题已经... 随着当前社会经济的不断发展与提升,人们对电力的要求也变的越来越大。对此,如果想要满足当前人们的电力需要,那么就需要在一定的程度上加强电厂的工作效率。但是,在当前的情况下,电厂存在着化学水处理设备设施腐蚀的问题,这些问题已经严重影响到了电厂的工作效率,还会让这些化学水处理设备设施造成严重的损害,为电厂带来一定的经济损失。主要分析了电厂化学水处理设备设施腐蚀的问题,并提出了相关的解决方法和建议。 展开更多
关键词 电厂 化学水 处理 设备设施 腐蚀问题 处理方法
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Male Urethral Strictures in Ouagadougou (Burkina Faso): Epidemiological Diagnostic and Therapeutic Aspects 认领
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作者 Clotaire Alexis Marie Kiemdiba Donega Yaméogo Mahamat Ali Mahamat +4 位作者 Brahima Kirakoya Adama Ouattara Tiéoule M. Traoré Bienvenu Ky Fasnewendé Aristide Kaboré 《泌尿学期刊(英文)》 2020年第4期101-110,共10页
Purpose: To conduct a study of epidemiological, diagnostic and therapeutic aspects of urethral strictures at Yalgado Ouedraogo University Teaching Hospital. Patients and methods: It was about a retrospective and descr... Purpose: To conduct a study of epidemiological, diagnostic and therapeutic aspects of urethral strictures at Yalgado Ouedraogo University Teaching Hospital. Patients and methods: It was about a retrospective and descriptive study conducted in the urology division of Yalgado Ouedraogo Hospital from October 1st 2009 to September 30th 2014. All the patients, included in this study, had a urethral stricture confirmed by the voiding retrograde cystourethrogram (VCUG) or during surgical intervention with useful surgical report and medical file. Results: During the period of study, 127 complete medical records were found. The hospital prevalence was 10.1%. The average age of the patients was 50.5 (from 3 to 80 years). 55.6% of the patients were from rural areas. Dysuria and urinary retention were the major causes of consultation with respectively 66.7% and 33.3%. The aetiology of urethral stricture was infectious in 71.4% of the cases. The VCUG permitted to objectify the characteristics of the stenosis. The urethral stenoses were single in the majority of the cases, about 88.8% of cases. The bulbar urethral stricture was the major location. Escherichia coli was isolated in 77.7% of the urinary infections. The majority of patients (61.9%) had undergone open surgery including 39.7% end to end anastomosis. No endoscopic treatment was recorded. Conclusion: The urethral stenosis is frequent in our division. Its major aetiology is infectious. The treatment is dominated by open surgery in our context. 展开更多
关键词 STRICTURE URETHRA Treatment Epidemiology
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Optimal treatment strategies for hepatic portal venous gas:A retrospective assessment 认领
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作者 Masanori Gonda Tatsuya Osuga +3 位作者 Yoshihiro Ikura Kazunori Hasegawa Kentaro Kawasaki Takatoshi Nakashima 《世界胃肠病学杂志:英文版》 SCIE CAS 2020年第14期1628-1637,共10页
BACKGROUND Hepatic portal venous gas(HPVG)generally indicates poor prognoses in patients with serious intestinal damage.Although surgical removal of the damaged portion is effective,some patients can recover with cons... BACKGROUND Hepatic portal venous gas(HPVG)generally indicates poor prognoses in patients with serious intestinal damage.Although surgical removal of the damaged portion is effective,some patients can recover with conservative treatments.AIM To establish an optimal treatment strategy for HPVG,we attempted to generate computed tomography(CT)-based criteria for determining surgical indication,and explored reliable prognostic factors in non-surgical cases.METHODS Thirty-four cases of HPVG(patients aged 34-99 years)were included.Necessity for surgery had been determined mainly by CT findings(i.e.free-air,embolism,lack of contrast enhancement of the intestinal wall,and intestinal pneumatosis).The clinical data,including treatment outcomes,were analyzed separately for the surgical cases and non-surgical cases.RESULTS Laparotomy was performed in eight cases(surgical cases).Seven patients(87.5%)survived but one(12.5%)died.In each case,severe intestinal damage was confirmed during surgery,and the necrotic portion,if present,was removed.Non-occlusive mesenteric ischemia was the most common cause(n=4).Twentysix cases were treated conservatively(non-surgical cases).Surgical treatments had been required for twelve but were abandoned because of the patients’poor general conditions.Surprisingly,however,three(25%)of the twelve inoperable patients survived.The remaining 14 of the 26 cases were diagnosed originally as being sufficiently cured by conservative treatments,and only one patient(7%)died.Comparative analyses of the fatal(n=10)and recovery(n=16)cases revealed that ascites,peritoneal irritation signs,and shock were significantly more frequent in the fatal cases.The mortality was 90%if two or all of these three clinical findings were detected.CONCLUSION HPVG related to intestinal necrosis requires surgery,and our CT-based criteria are probably useful to determine the surgical indication.In non-surgical cases,ascites,peritoneal irritation signs and shock were closely associated with poor prognoses,and are applicable as pred 展开更多
关键词 Hepatic portal venous gas Surgical treatment Conservative treatment Computed tomography Intestinal necrosis Prognostic factor
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Treatment of Uncomplicated Malaria among Under-Five Children: A Systematic Review 认领
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作者 Ndukaku Nwakwue Mary Achi Mgbekem +4 位作者 Alberta David Nsemo Margaret Armon Regina Ella Ifreke Willie Akpan Pricilla Adrew-Bassey 《健康(英文)》 2020年第4期378-395,共18页
Most uncomplicated malaria dominated countries have embraced the recommended first-line treatment of uncomplicated malaria. Artemisinin-based combination therapies such as Artemether-Lumefantrine, Artesunate + Amodiaq... Most uncomplicated malaria dominated countries have embraced the recommended first-line treatment of uncomplicated malaria. Artemisinin-based combination therapies such as Artemether-Lumefantrine, Artesunate + Amodiaquine and Dihydroartemisinin-Piperaquine have shown to be effective with Artemether-Lumefantrine and considered the most effective and approved by WHO. The study collected and reviewed recent randomized controlled trials for the treatment of uncomplicated malaria under five children. Eligibility criteria for the selected studies were based on the use of tools such as PICO (T) and data extraction tools such as REPOSE guidelines, PRISMA statement and eligibility criteria. This study includes only RCTs on the treatment of uncomplicated malaria under 5 s. Data was analyzed through comparative-narrative analysis. This study found 8 studies. Selected studies had a total of 10,682 participants within the age range of 0 - 59 months with the diagnosis of uncomplicated malaria and an MCP range of 2000 - 200,000 treated with different antimalarial drugs. Artesunate + Amodiaquine and Dihydroartemisinin-Piperaquine and Artemether-Lumefantrine drugs were found to be consistent in the treatment of uncomplicated malaria under 5 s within three days. Findings show that Artemether-Lumefantrine, Artesunate + Amodiaquine and Dihydroartemisinin-Piperaquine were the best drugs of choice due to their fast rate in fever reduction and parasite clearance. The efficacy of Artesunate + Amodiaquine and Dihydroartemisinin-Piperaquine is comparable to Dihydroartemisinin-Piperaquine. The study concludes that Artesunate + Amodiaquine and Dihydroartemisinin-Piperaquine can also be drugs of choice along with the well-known and utilized Artemether-Lumefantrine combination because of the fever reduction and parasite clearance within the first three days duration. 展开更多
关键词 MALARIA Under-Five ANTIMALARIAL TREATMENT UNCOMPLICATED MALARIA ACTS
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Multidisciplinary treatment of soft tissue sarcomas:An update 认领
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作者 Jorge Gómez Panagiotis Tsagozis 《世界临床肿瘤学杂志:英文版》 2020年第4期180-189,共10页
Standard treatment for soft tissue sarcoma,based on complete surgical resection with or without adjuvant radiotherapy and chemotherapy,has not substantially changed during the last several decades.Nevertheless,recent ... Standard treatment for soft tissue sarcoma,based on complete surgical resection with or without adjuvant radiotherapy and chemotherapy,has not substantially changed during the last several decades.Nevertheless,recent advances have contributed to considerable improvement in the management of these patients;for example,new magnetic resonance imaging sequences such as diffusionweighted imaging and magnetic resonance imaging radiomics can better assess tumor extension and even estimate its grade.Detection of circulating genetic material(liquid biopsy)and next-generation sequencing are powerful techniques for genetic analysis,which will increase our understanding of the underlying molecular mechanisms and may reveal potential therapeutic targets.The role of chemotherapy in non-metastatic disease is still controversial,and there is a need to identify patients who really benefit from this treatment.Novel chemotherapeutic regimens have entered clinical praxis and can change the outcome of patients with metastatic disease.Advances in radiotherapy have helped decrease local adverse effects and sustain good local control of the disease.The following report provides an updated view of the diagnosis,treatment,and future perspectives on the management of patients with soft tissue sarcomas. 展开更多
关键词 Soft tissue sarcomas Multidisciplinary treatment SURGERY RADIOTHERAPY CHEMOTHERAPY Targeted therapy Update treatment
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