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无偿献血者季节性招募方式对全血及红细胞类成分血采、供血工作的影响
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作者 刘艳红 朱和鸣 刘春玲 《国际输血及血液学杂志》 CAS 2019年第3期194-200,共7页
目的探讨无偿献血者季节性招募方式,对全血及红细胞类成分血采供血工作的影响。方法选择2013年1月至2018年12月于滨州市中心血站,参加全血及红细胞类成分血献血的239 949例无偿献血者为研究对象。其中,男性献血者为165 564例,女性为74 ... 目的探讨无偿献血者季节性招募方式,对全血及红细胞类成分血采供血工作的影响。方法选择2013年1月至2018年12月于滨州市中心血站,参加全血及红细胞类成分血献血的239 949例无偿献血者为研究对象。其中,男性献血者为165 564例,女性为74 385例;献血者年龄为18~55岁。采用启奥血站信息管理系统v9.0(唐山启奥科技有限公司),收集本研究239 949例献血者参与献血的时间、献血模式、全血和红细胞类成分血的采血量,以及全血及红细胞类成分血的供血量等献血相关资料。分别计算2013-2018年滨州市中心血站各季节的全血及红细胞类成分血采血量、采血量季节比率、全血及红细胞类成分血的供血量、供血量季节比率,以及采、供血量季节比率差。对2013-2018年滨州市中心血站的4个季节全血及红细胞类成分血的采血量、供血量总体比较,采用方差分析,各季节间两两比较,采用最小显著差数(LSD)法。本研究遵循的程序符合2013年修订的《世界医学协会赫尔辛基宣言》的要求,献血前与献血者均签署《献血者知情同意书》。结果①本研究滨州市中心血站2013-2018年春、夏、秋、冬4个季节全血及红细胞类成分血的采血量季节比率,依次分别为95.8%、93.8%、113.4%和97.0%;团体采血量季节比率,依次分别为39.9%、56.7%、190.3%和113.2%;街头采血量季节比率,依次分别为117.9%、108.5%、83.1%和90.6%。滨州市中心血站2013-2018年春、夏、秋、冬4个季节全血及红细胞类成分血的采血量,依次分别为(15 877.0±924.3)U、(15 548.2±1 105.3)U、(18 790.8±1 057.7)U和(16 065.7±1 062.3)U,4个季节采血量总体比较,差异有统计学意义(F=12.418,P<0.001),其中秋季采血量,分别高于春、夏和冬季,并且差异均有统计学意义(t=4.854、5.402、4.540,P<0.001)。②滨州市中心血站2013-2018年春、夏、秋、冬4个季节全血及红细胞类成分血的供血量季节� 展开更多
关键词 血液 季节性招募 无偿献血者 血液采集 血液供应 团体献血 街头献血
An Emergency Blood Allocation Approach Considering Blood Group Compatibility in Disaster Relief Operations
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作者 Zu-Jun Ma Ke-Ming Wang Ying Dai 《国际灾害风险科学学报:英文版》 CSCD 2019年第1期74-88,共15页
Large-scale sudden-onset disasters may cause massive injuries and thus place great pressure on the emergency blood supplies of local blood banks. When blood is in short supply, blood products gathered urgently to a lo... Large-scale sudden-onset disasters may cause massive injuries and thus place great pressure on the emergency blood supplies of local blood banks. When blood is in short supply, blood products gathered urgently to a local blood center should be appropriately allocated to blood banks in the affected area. Moreover, ABO/Rh(D) compatibilities among blood groups must be considered during emergency situations. To minimize the total unmet demand of blood products considering the optimal ABO/Rh(D)-compatible blood substitution scheme, a mixed integer programming model is developed and solved efficiently by using a greedy heuristic algorithm. Finally, a numerical example derived from the emergency blood supply scenario of the Wenchuan Earthquake is presented to verify the proposed model and algorithm. The results show that considering ABO/Rh(D)-compatible blood substitution can remarkably increase the efficiency of emergency blood allocation while lowering blood shortage, and the preference order of possible ABO/Rh(D)-compatible substitutions has an influence on the allocation solution. 展开更多
关键词 BLOOD group compatibility BLOOD substitution Disaster RELIEF EMERGENCY BLOOD ALLOCATION GREEDY HEURISTIC algorithm
Blood Pressure Variability and Its Relationship with Cognitive Function in Elderly Patients with Essential Hypertension and Type 2 Diabetes 预览
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作者 Man Xu 《老年医学(英文)》 2019年第1期1-7,共7页
Objective: To investigate blood pressure variability of Elder hypertensives with type 2 diabetes and its relationship with cognition. Methods: A total of 143 elderly hypertensives were enrolled and divided into diabet... Objective: To investigate blood pressure variability of Elder hypertensives with type 2 diabetes and its relationship with cognition. Methods: A total of 143 elderly hypertensives were enrolled and divided into diabetic group (59 cases) and non-diabetic group (84 cases). The difference of general clinical characteristics, biochemical parameters, carotid ultrasound, a neuropsychological Scales and 24-hour ambulatory blood pressure (24hABPM) parameters between the two groups of subjects were compared. Then, the two groups (diabetic group and non-diabetic group) were further divided into (Mild cognitive dysfunction) subgroup (MMSE>26) and normal cognition subgroup (MMSE≤26), respectively. On the basis of MMSE scores, the difference of the parameters of ABPM between the two subgroups was analyzed. Results: Compared with the control group, 24hSBP, 24hPP, dSBP, dPP, nSBP, nPP, 24hSSD, dSSD, nSSD, 24hSCV, dSCV and nSCV were significantly higher in the diabetic group (p<0.05). However, cognition was lower in the diabetic group. No significant difference was found in the circadian pattern of blood pressure between the two groups. 24hSSD, dSSD, nSSD, 24hSCV, dSCV, nSCV were significantly higher in the MCI subgroup than normal cognition subgroup in both diabetic and non-diabetic groups(p<0.05), and they were negatively associated with scores of MMSE, the correlation coefficient were -0.235,-0.246,-0.341,-0.158,-0.222,-0.238 (0.001≤P<0.05). Conclusion: The study showed that in the elderly with hypertension, the mean systolic blood pressure and blood pressure variability were both higher in the diabetic group, and the cognition was lower instead. Whether or not with diabetes, blood pressure variability was always higher in the MCI subgroup. Blood pressure variability increased in patients with diabetes, and was associated with cognitive decline. 展开更多
关键词 MILD cognitive DYSFUNCTION BLOOD PRESSURE variability diabetes hypertension 24-hour AMBULATORY BLOOD PRESSURE
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先秦两汉时期中医对“血”的认识 预览
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作者 梁秋语 王群 +3 位作者 罗浩 张延丞 张烁 熊益亮 《世界中医药》 CAS 2019年第7期1692-1695,共4页
现就目前已经完成整理并公布的先秦两汉出土文献中“血”的相关资料进行系统整理,并旁参《黄帝内经》和其他先秦两汉传世经典文献,以期梳理出这一时期中医对“血”的认识。整理按照血与生命的联系、血与气及其相关问题、血的转化和相关... 现就目前已经完成整理并公布的先秦两汉出土文献中“血”的相关资料进行系统整理,并旁参《黄帝内经》和其他先秦两汉传世经典文献,以期梳理出这一时期中医对“血”的认识。整理按照血与生命的联系、血与气及其相关问题、血的转化和相关的禁忌、病证及治疗几个角度进行,结果显示:1)人们关于血的认识,总是以生命作为起点;2)血与气关系密切,目前出土的文献中以血气出现的频率较高,而不是气血;3)血的转化有生理性的也有病理性的;4)先秦两汉时期血相关病证很多,血忌日是针灸家时日忌针说的来源。当时的人们对于血的认识包括生理和文化2个层面,并且这2个层面的认识既相对独立、相互交织,又相互影响。 展开更多
关键词 先秦两汉 中医 生命 转化 血忌日 出土文献
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Effect of lipid lowering mixture on blood lipid metabolism, LDL oxidation susceptibility and blood viscosity and coagulation in experimental hyperlipidemia rats
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作者 Xue-Bing Luan Fu-Chen Zhang +2 位作者 Zhi-Yuan Weng Yu Zhang Liang Ma 《海南医科大学学报(英文版)》 2019年第4期17-20,共4页
Objective:To investigate the effect of lipid lowering mixture on blood lipid metabolism, LDL oxidative susceptibility and blood viscosity and coagulation in experimental hyperlipidemia rats.Method: Select 60 male Wist... Objective:To investigate the effect of lipid lowering mixture on blood lipid metabolism, LDL oxidative susceptibility and blood viscosity and coagulation in experimental hyperlipidemia rats.Method: Select 60 male Wistar rats were randomly divided into six groups, ten rats in each group were recorded as low as lipid-lowering mixture, high dose group and simvastatin group, model group and control group. Patients in control group were treated with basic feed for feeding, other groups of rats are used high fat diet were fed to establish hyperlipidemia rat model, in the process of modeling and prophylactically, determination of rats after 10 weeks of lipid metabolism and susceptibility of LDL to oxidation and blood viscosity concentration coagulation state.Result: Antioxidant capacity of the model group rat's serum LDL-C decreased significantly, and simvastatin group and three groups of lipid-lowering mixture group rats serum LDL antioxidant capacity were significantly enhanced;and high lipid mixture, LDL antioxidant ability in middle dose group rats were significantly higher than those of the Jiangzhi Decoction low dose group rats (P<0.05). Lipid mixture of high, middle dose group rats of EET and ETA P, ETA B (high, medium and low shear), IED, HCT, the role of the IEA was significantly higher in Jiangzhi Decoction low dose group rats (P<0.05 or P<0.05).Conclusion:Lipid-lowering mixture on experimental hyperlipidemia rats blood lipid metabolism and blood viscosity concentration coagulation state has a good regulatory role, and lipid-lowering mixture on blood lipid and blood flow abnormalities lipid-lowering mixture can also play a good regulation and therapeutic effect. 展开更多
关键词 HYPERLIPEMIA LIPID lowering MIXTURE BLOOD LIPID METABOLISM BLOOD COAGULATION state LIPID carrier protein
2011-2017年广州血液中心血液报废原因分析
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作者 游冉冉 罗伟峰 +2 位作者 李然 周豪杰 黄可君 《热带医学杂志》 CAS 2019年第2期177-180,共4页
目的通过分析广州血液中心血液制品报废量及其原因,降低血液报废率。方法收集2011-2017年的血液报废情况,针对不同的报废原因作回顾性分析。结果 2011-2017年广州血液中心共采集制备6 655 046 U血液,报废血液总量414 512 U,其中因实验... 目的通过分析广州血液中心血液制品报废量及其原因,降低血液报废率。方法收集2011-2017年的血液报废情况,针对不同的报废原因作回顾性分析。结果 2011-2017年广州血液中心共采集制备6 655 046 U血液,报废血液总量414 512 U,其中因实验室检测不合格报废的血量为216 488 U,报废率3.25%。实验室检测不合格血液报废率在2011-2017年逐年下降,其中最常见的原因是丙氨酸转移酶(ALT)(1.33%)不合格,其后依次是HBsAg(0.83%),梅毒(0.41%),抗?HCV(0.35%),核酸检测(0.21%)。非实验室检测不合格报废的血量为198 024 U,报废率2.98%。非实验室检测不合格血液报废率在2011-2017年逐年上升,并在2015年超过了实验室检测不合格血液报废率。乳糜血(2.37%)和破袋(0.15%)是非实验室检测不合格血液报废的主要原因。结论近7年血液报废主要原因构成有所变化,前4年以实验室检测报废为主,2015年开始以非实验室检测报废为主。应意识到血液报废的严重性并提出相应对策,减少血液报废,确保血液质量和输血安全。 展开更多
关键词 血液 报废 无偿献血 广州
Analysis on the rules of prescriptions for ischemic stroke based on the traditional Chinese medicine inheritance auxiliary system 预览
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作者 Jing-Na Zhou Zi-Qi Jing +1 位作者 Xin-Zhe Zhao Guo-Wei Zhang 《TMR药物联合治疗》 2019年第2期65-74,共10页
In China,traditional Chinese medicine is widely used in the treatment of ischemic stroke,but its prescription rules needs to be further studied.This paper uses the traditional Chinese medicine inheritance auxiliary sy... In China,traditional Chinese medicine is widely used in the treatment of ischemic stroke,but its prescription rules needs to be further studied.This paper uses the traditional Chinese medicine inheritance auxiliary system(a software)to analyze the composition rules of a large number of prescriptions for the treatment of ischemic stroke,and discusses the clinical rationality of the new prescriptions.We found that the prescriptions for the treatment of ischemic stroke are mainly composed by herbs for promoting blood circulation and removing blood stasis,dredging collaterals and tonifying deficiency,and some of the new prescriptions are also in line with this characteristic.This paper can provide reference for clinical prescription in the treatment of ischemic stroke and the development of related new drugs. 展开更多
关键词 Ischemic stroke Traditional Chinese medicine INHERITANCE AUXILIARY SYSTEM Prescription rule Promoting BLOOD circulation and removing BLOOD STASIS
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Impact of perioperative transfusion in patients undergoing resection of colorectal cancer liver metastases:A population-based study 预览
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作者 Bo Long Zhen-Nan Xiao +2 位作者 Li-Hua Shang Bo-Yan Pan Jun Chai 《世界临床病例杂志》 2019年第10期1093-1102,共10页
BACKGROUND Perioperative allogeneic blood transfusion is associated with poorer outcomes.AIM To identify the factors that were associated with perioperative transfusion and to examine the impact of perioperative trans... BACKGROUND Perioperative allogeneic blood transfusion is associated with poorer outcomes.AIM To identify the factors that were associated with perioperative transfusion and to examine the impact of perioperative transfusion in patients undergoing resection of colorectal cancer(CRC)liver metastases.METHODS The United States National Inpatient Sample(NIS)database was searched for patients with CRC who received surgery for liver metastasis.Linear and logistic regression analyses were performed.RESULTS A total of 2018 patients were included,and 480 had a perioperative transfusion.Emergency admission(adjusted odds ratio[aOR]=1.42;95%CI:1.07-1.87),hepatic lobectomy(aOR=1.76;95%CI:1.42-2.19),and chronic anemia(aOR=2.62;95%CI:2.04-3.35)were associated with increased chances of receiving a transfusion,but receiving surgery at a teaching hospital(aOR=0.75;95%CI:0.58-0.98)was associated with a decreased chance of receiving a transfusion.Receiving a perioperative transfusion was significantly associated with increased in-hospital mortality(aOR=3.38;95%CI:1.57-7.25),and increased overall postoperative complications(aOR=1.67;95%CI:1.31-2.13),as well as longer length of hospital stay CONCLUSION Patients with an emergency admission,hepatic lobectomy,chronic anemia,and who have surgery at a non-teaching hospital are more likely to receive a perioperative transfusion.Patients with CRC undergoing surgery for hepatic metastases who receive a perioperative transfusion are at a higher risk of inhospital mortality,postoperative complications,and longer length of hospital stay. 展开更多
关键词 Colorectal cancer Liver metastasis PERIOPERATIVE BLOOD TRANSFUSION INTRAOPERATIVE BLOOD loss National INPATIENT sample
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试论“血之源头在乎肾”
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作者 崔家康 姜泉 《中医学报》 CAS 2019年第4期686-688,共3页
血在脉道中运行,流注周身,循环不已,维持人体正常的生理活动。肾为先天之本,肾主藏精,肾阴肾阳为五脏阴阳之本,其在血生成的过程中起着非常重要的作用,肾也影响着血行,故有'血之源头在乎肾'之说。肾精、肾气、肾阴、肾阳在血化... 血在脉道中运行,流注周身,循环不已,维持人体正常的生理活动。肾为先天之本,肾主藏精,肾阴肾阳为五脏阴阳之本,其在血生成的过程中起着非常重要的作用,肾也影响着血行,故有'血之源头在乎肾'之说。肾精、肾气、肾阴、肾阳在血化生的过程中起着关键的作用,肾是血化生的本原和动力,血液运行同样与肾关系密切,肾虚可导致血虚,亦可引起瘀血、出血等病理改变。在治疗上,当遵'损其肾者益其精''形不足者,温之以气;精不足者,补之以味'的原则,具体方法有填肾精益精髓而资血、温肾阳益肾气而养血、平补肾阴肾阳而生血等。 展开更多
关键词 肾精 肾阴 血行
Effects of Xuezhikang (Red Yeast Rice) on Blood lipids, Hemorheology and the Expression of P65 and Tissue Factor in Atherosclerotic Rats 预览
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作者 Yabing Yang Meilin Liu 《医学科学进展杂志(英文)》 2019年第1期10-15,共6页
Objective: To observe the effects of Xuezhikang (red yeast rice) on blood lipids, blood rheology, and expression of P65 and tissue factor, and to explore the anti-atherosclerosis effect and related mechanisms of Xuezh... Objective: To observe the effects of Xuezhikang (red yeast rice) on blood lipids, blood rheology, and expression of P65 and tissue factor, and to explore the anti-atherosclerosis effect and related mechanisms of Xuezhikang (red yeast rice). Methods: 32 Wistar rats were randomly divided into normal control group, Xuezhikang treatment group, lovastatin treatment group and atherosclerosis model group (8 in each group). Blood lipids, blood rheology, malondialdehyde (MDA), total antioxidant capacity (T-AOC), and expression of aortic tissue factor (TF) and P65 were measured in each group. Results:(1) Both Xuezhikang and lovastatin could reduce blood lipid levels, but there was no significant difference between the two groups;(2) Both Xuezhikang and lovastatin can improve the hemorheology of atherosclerotic rats, but the difference between the two groups is not significant;(3) Compared with lovastatin, Xuezhikang inhibited the expression of TF and P65 in aorta of rats with atherosclerosis;(4) Compared with lovastatin, the Xuezhikang group had lower MDA levels and higher T-AOC. Conclusion: Xuezhikang can improve blood lipid levels and hemorheology in rats with atherosclerosis. Compared with lovastatin, Xuezhikang has stronger effects on inhibiting oxidative stress and down-regulating the expression of tissue factor and P65. 展开更多
关键词 Xuezhikang Atherosclerosis BLOOD LIPIDS BLOOD RHEOLOGY Tissue factor P65
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Efficacy of Danlou Tablet in the Treatment of Coronary Heart Disease with Phlegm and Blood Stasis Syndrome and Its Effects on Serum Inflammatory Factors 预览
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作者 Jinfeng CHEN Zhongyi LEI +5 位作者 Chaofeng LIU Hong FAN Xueping WU Xiaoyong YU Peng LEI Yong WANG 《药用植物研究(英文版)》 2019年第3期87-89,92共4页
[Objectives] To explore the efficacy of Danlou Tablet( DLT) in the treatment of coronary heart disease( CHD) with phlegm and blood stasis syndrome and its effects on serum inflammatory factors. [Methods]One hundred an... [Objectives] To explore the efficacy of Danlou Tablet( DLT) in the treatment of coronary heart disease( CHD) with phlegm and blood stasis syndrome and its effects on serum inflammatory factors. [Methods]One hundred and ninety-seven patients with CHD and phlegm and blood stasis syndrome in our hospital from January 2016 to January 2018 were selected and randomly divided into two groups: control group( n =98) treated with aspirin plus atorvastatin,and research group( n =99) treated with DLT and aspirin plus atorvastatin for one month. The clinical efficacy and incidence of adverse reactions were observed. Serum secretory phospholipase A2( s PLA2),lipoprotein-associated phospholipase A2( LP-PLA2),oxidized low-density lipoprotein( ox-LDL),monocyte chemoattractant protein-1( MCP-1) and World Health Organization Quality of Life( WHOQOL-100) scores were compared before and after one month of treatment. [Results] The total effective rate was93. 94% in the research group,which was higher than that in the control group( 79. 59%,P < 0. 05);the levels of serum s PLA2,LP-PLA2,ox-LDL and MCP-1 in the research group were lower than those in the control group after one month of treatment( P < 0. 05). There was no statistical significance of the difference in the total incidence of adverse reactions between the research group and the control group( P > 0. 05).After one month of treatment,WHOQOL-100 scores were higher in two groups,which were higher in the research group than that in the control group( P < 0. 05). [Conclusions]DLT can significantly reduce the level of serum inflammatory factors,improve the quality of life in patients with CHD and phlegm and blood stasis syndrome. 展开更多
关键词 Coronary heart disease(CHD) PHLEGM and BLOOD STASIS SYNDROME Danlou Tablet(DLT) Inflammatory factors BLOOD lipid
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Effects of Activating Blood Circulation to Resolve Blood Stasis and Glucosamine Capsules Therapy on the Expression of Matrix Metalloproteinase in Post-traumatic Knee Osteoarthritis 预览
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作者 Mingguang CHEN Shiqiang CHEN +5 位作者 Ning YANG Jin YANG Yingang LI Xiaoxia CAO Chunfeng CHANG Xuelan WU 《药用植物研究(英文版)》 2019年第3期77-81,86共6页
[Objectives] To observe the clinical effects of activating blood circulation to resolve blood stasis and glucosamine hydrochloride capsules therapy on post-traumatic knee osteoarthritis treatment,to measure the expres... [Objectives] To observe the clinical effects of activating blood circulation to resolve blood stasis and glucosamine hydrochloride capsules therapy on post-traumatic knee osteoarthritis treatment,to measure the expression of matrix metalloproteinase in post-traumatic knee osteoarthritis patients before and after treatment,and to explore its relevant molecular mechanisms. [Methods]A total of 60 patients with posttraumatic knee osteoarthritis in early stage in Affiliated Hospital of Shannxi University of Chinese Medicine from January 2015 to December2017 were selected and randomly divided into the control group( n = 30) and the observation group( n = 30). The control group was given oral administration of glucosamine hydrochloride capsules for 6 courses of the treatment. The observation group was using the activating blood circulation to resolve blood stasis therapy for 6 courses of treatment. The recovery of traumatic knee osteoarthritis and the symptom of traditional Chinese medicine( TCM) in 2 groups was compared before and after treatment. The symptoms and the quantitative assessment rating scale of knee osteoarthritis,the pain index of knee and the TCM symptom scores were recorded in both groups. And the synovial fluid and serum of patients were collected to detect the expression of matrix metalloproteinase. [Results]The symptoms and the quantitative assessment rating scale of knee osteoarthritis,the pain index of knee and TCM symptom scores of the 2 groups in the 1 st week,the 12 th week and the 24 th week after the treatment were significantly lower than those before the treatment,and the difference was statistically significant( P < 0. 05). Two therapeutic methods had certain therapeutic effects on the recovery from traumatic knee osteoarthritis,and could significantly improve the TCM syndrome. There were better therapeutic effects on oral decoction of traditional Chinese medicine than oral glycosaminoglycans hydrochloride capsules on treating traumatic knee osteogenesis( P < 0. 05). The expression level of 展开更多
关键词 Activating BLOOD CIRCULATION to RESOLVE BLOOD stasis GLUCOSAMINE hydrochloride Osteoarthritis Knee joint MATRIX metalloproteinases-1 MATRIX metalloproteinases-3 MATRIX metalloproteinases-13 Therapeutic effects
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Heavy metals in maternal and cord blood in Beijing and their efficiency of placental transfer
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作者 Aijing Li Taifeng Zhuang +2 位作者 Jianbo Shi Yong Liang Maoyong Song 《环境科学学报:英文版》 SCIE EI CAS CSCD 2019年第6期99-106,共8页
This study aimed to determine the effect of exposure to heavy metals in pregnant women in Beijing, China. We also evaluated the association of these heavy metals with birth weight and length of newborns. We measured t... This study aimed to determine the effect of exposure to heavy metals in pregnant women in Beijing, China. We also evaluated the association of these heavy metals with birth weight and length of newborns. We measured the levels of 10 heavy metals,including lead(Pb), titanium(Ti), manganese(Mn), nickel(Ni), cadmium(Cd), chromium(Cr), antimony(Sb), stannum(Sn), vanadium(V), and arsenic(As), in 156 maternal and cord blood pairs. An inductively coupled plasma mass spectrometry method was used for measurement. Pb, As, Ti, Mn, and Sb showed high detection rates(> 50%) in both maternal and cord blood. Fourteen(9%) mothers had blood Pb levels greater than the United States Center for Disease Control allowable threshold limit for children(50 μg/L).In prenatal exposure to these heavy metals, there was no significant association between any heavy metal and birth weight/length. Moreover, we estimated the placental transfer efficiency of each heavy metal, and the median placental transfer efficiency ranged from 49.6%(Ni) to 194%(Mn)(except for Cd and Sn). The level and detection rate of Cd in maternal blood were much higher than that in cord blood, which suggested that Cd had difficulty in passing the placental barrier. Prospective research should focus on the source and risk of heavy metals in non-occupationally exposed pregnant women in Beijing. 展开更多
关键词 Heavy metal MATERNAL BLOOD Cord BLOOD NEWBORN PLACENTAL transfer EFFICIENCY
Retrospective evaluation of lymphatic and blood vessel invasion and Borrmann types in advanced proximal gastric cancer 预览
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作者 Shan Gao Guo-Hui Cao +5 位作者 Peng Ding Yang-Yang Zhao Peng Deng Bin Hou Kai Li Xiao-Fang Liu 《世界胃肠肿瘤学杂志:英文版(电子版)》 CAS 2019年第8期642-651,共10页
BACKGROUND The Borrmann classification system is used to describe the macroscopic appearance of advanced gastric cancer,and Borrmann typeⅣdisease is independently associated with a poor prognosis.AIM To evaluate the ... BACKGROUND The Borrmann classification system is used to describe the macroscopic appearance of advanced gastric cancer,and Borrmann typeⅣdisease is independently associated with a poor prognosis.AIM To evaluate the prognostic significance of lymphatic and/or blood vessel invasion(LBVI)combined with the Borrmann type in advanced proximal gastric cancer(APGC).METHODS The clinicopathological and survival data of 440 patients with APGC who underwent curative surgery between 2005 and 2012 were retrospectively analyzed.RESULTS In these 440 patients,LBVI+status was associated with Borrmann typeⅣ,low histological grade,large tumor size,and advanced pT and pN status.The 5-year survival rate of LBVI+patients was significantly lower than that of LBVI– patients,although LBVI was not an independent prognostic factor in the multivariate analysis.No significant difference in the prognosis of patients with Borrmann typeⅢ/LBVI+disease and patients with Borrmann typeⅣdisease was observed.Therefore,we proposed a revised Borrmann typeⅣ(r-BorⅣ)as Borrmann typeⅢplus LBVI+,and found that r-BorⅣwas associated with poor prognosis in patients with APGC,which outweighed the prognostic significance of pT status.CONCLUSION LBVI is related to the prognosis of APGC,but is not an independent prognostic factor.LBVI status can be used to differentiate Borrmann typesⅢandⅣ,and the same approach can be used to treat r-BorⅣand Borrmann typeⅣ. 展开更多
关键词 PROXIMAL gastric cancer LYMPHATIC and/or blood vessel INVASION BORRMANN TYPES Prognosis
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十堰市血液库存管理现状SWOT分析及建议
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作者 田海燕 陈晓霞 陈继勤 《中国输血杂志》 CAS 2019年第4期393-395,共3页
目的了解十堰市血液库存管理现状,为提升血液库存管理水平,保障辖区内血液供应提供决策依据。方法采用SWOT分析法对十堰市2014-2017年血液采集、供应和库存管理情况进行分析。结果十堰市血液库存管理的优势(S):无偿献血氛围良好,血源相... 目的了解十堰市血液库存管理现状,为提升血液库存管理水平,保障辖区内血液供应提供决策依据。方法采用SWOT分析法对十堰市2014-2017年血液采集、供应和库存管理情况进行分析。结果十堰市血液库存管理的优势(S):无偿献血氛围良好,血源相对充足;全省血液互动调剂,可有效调节库存量。劣势(W):绩效考核模式不利于血液采集计划的调控;供血区域跨度大,送血及时性有待提升;临床不合理用血和不合理库存影响血站的库存管理。机会(O):自体输血和科学用血的管控有利于降低供需矛盾;循证医学的发展为血站参与临床输血管理提供机遇。威胁(T):临床用血和无偿献血的不确定性;血液替代品的研发使用;设备和人员短缺;血液应急预案的响应能力都在不同程度影响血液库存管理。结论采供血机构需充分利用优势,有效规避劣势和风险,建立合理高效的血液库存管理机制,确保临床血液供应需求性和及时性。 展开更多
关键词 血液 库存管理 SWOT分析
Effects of High Intensity Interval Exercise on Blood Pressure 预览
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作者 Xiaoyu Wei 《校园英语》 2019年第18期255-256,共2页
This paper reviews the effect of high intensity interval exercise on blood pressure and discussed the mechanism of decreasing blood pressure.
关键词 High INTENSITY INTERVAL EXERCISE BLOOD PRESSURE Effect
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QuEChERS-超高效液相色谱-串联质谱法测定血液中4种乌头类生物碱 预览
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作者 钟世豪 任昕昕 +4 位作者 于忠山 董林沛 何亚 何欣龙 姜晓佳 《理化检验:化学分册》 CAS CSCD 北大核心 2019年第5期591-596,共6页
移取1.00mL血液样品,加入2mL乙腈和50mg氯化钠,振荡10min后,在-4℃下以8 000r·min-1转速离心10min,取上清液,加入15mg N-丙基乙二胺和25mg十八烷基硅烷,振荡5min,重复上述离心操作,取上清液,过0.22μm有机微孔膜,采用超高效液相色... 移取1.00mL血液样品,加入2mL乙腈和50mg氯化钠,振荡10min后,在-4℃下以8 000r·min-1转速离心10min,取上清液,加入15mg N-丙基乙二胺和25mg十八烷基硅烷,振荡5min,重复上述离心操作,取上清液,过0.22μm有机微孔膜,采用超高效液相色谱-串联质谱法测定滤液中次乌头碱、新乌头碱、乌头碱和滇乌头碱等4种乌头类生物碱的含量。以Agilent ZORBAX Eclipse Plus C18色谱柱为固定相,以不同体积比的0.1%(质量分数)氨水和甲醇的混合液为流动相进行梯度洗脱,串联质谱分析中采用电喷雾正离子源和多反应监测模式。4种乌头类生物碱的质量浓度在一定范围内与其对应的峰面积呈线性关系,方法的检出限(3S/N)为0.010~0.035μg·L-1。以空白样品为基体进行加标回收试验,所得回收率为96.3%~109%,回收量的日内相对标准偏差(n=6)为2.3%~4.2%,日间相对标准偏差(n=6)为0.70%~6.7%。 展开更多
关键词 超高效液相色谱-串联质谱法 QUECHERS 乌头类生物碱 血液
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高通量血液透析和低通量血液透析不同模式对老年维持性血液透析中血压的影响 预览
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作者 郭学文 《黑龙江医药》 CAS 2019年第2期288-291,共4页
目的:探讨高通量血液透析和低通量血液透析不用模式对老年维持性血液透析中血压的影响。方法:选取在本院进行维持性血液透析老年患者80例(2016年1月-2017年1月),采取数字表随机分组方法分成观察组、对照组各40例,观察组采取高通量血液... 目的:探讨高通量血液透析和低通量血液透析不用模式对老年维持性血液透析中血压的影响。方法:选取在本院进行维持性血液透析老年患者80例(2016年1月-2017年1月),采取数字表随机分组方法分成观察组、对照组各40例,观察组采取高通量血液透析方案,对照组采取低通量血液透析方案,比较两种方案临床治疗情况。结果:透析2小时、透析3小时,SBP、DBP有显著性差异(P<0.05),有统计学意义;观察组疗效优良率显著高于对照组(P<0.05),有统计学意义;观察组肾功能指标改善时间显著短于对照组肾功能改善时间(P<0.05),有统计学意义;透析后,两组C反应蛋白、甲状旁腺激素、血甘油三酯比较有显著性差异,(P<0.05),有统计学意义。结论:给予老年维持性血液透析患者采取高通量血液透析方案,有助于透析中血压值相对稳定,对于提高透析效果,缩短肾功能改善,特别对于改善相关临床指标有重要临床价值。 展开更多
关键词 高通量血液透析 低通量血液透析 维持性血液透析 血液
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Curative Effects of Warming Needle Moxibustion Combined with Manipulation Massage on Cervical Spondylotic Vertebral Arteriopathy and Its Influence on the Cerebral Blood Flow Parameters and Cervical Vertebral Function 预览
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作者 翟炳生 《世界中西医结合杂志(英文)》 2019年第3期17-23,共7页
OBJECTIVE: To explore the curative effects of warming needle moxibustion combined with manipulation massage on cervical spondylotic vertebral arteriopathy and its influence on the cerebral blood flow and cervical vert... OBJECTIVE: To explore the curative effects of warming needle moxibustion combined with manipulation massage on cervical spondylotic vertebral arteriopathy and its influence on the cerebral blood flow and cervical vertebra function. METHODS: A total of 84 patients with cervical spondylotic vertebral arteriopathy admitted to our hospital from February 2016 to June 2017 were selected, and all patients were divided into an observation group (n=42) and a control group (n=42) according to the random number table method. The patients in the control group were given conventional western treatment, and the patients in the observation group were treated with warming needle moxibustion combined with manipulation massage on the basis of the control group. After 4 weeks of treatment, the changes of main clinical symptoms (vertigo, headache, neck and shoulder pain, tinnitus), cervical function (clinical symptoms, clinical examination, daily life action) and cerebral blood flow parameters (average blood flow velocity of left vertebral artery, right vertebral artery and basilar artery) of the 2 groups were observed, and the clinical efficacy of the 2 groups were statistically analyzed. RESULTS: The scores of vertigo, headache, neck and shoulder pain and tinnitus in the 2 groups were all significantly lower than before treatment (P < 0.05), and the clinical symptom scores in the observation group were significantly lower after treatment (P < 0.05);After treatment, the scores of clinical symptoms, clinical examination and daily life action in the 2 groups were significantly higher than those before treatment (P < 0.05), and the increase of cervical vertebral function score in the observation group was better than that in the control group (P < 0.05);The mean blood flow velocity of the left vertebral artery, right vertebral artery and the basilar artery in the 2 groups after treatment were significantly higher than before treatment (P < 0.05), and the increase of the above cerebral blood flow parameters in the observation group wer 展开更多
关键词 CERVICAL spondylotic VERTEBRAL ARTERIOPATHY WARMING needle MOXIBUSTION Manipulation MASSAGE Cerebral blood flow parameters CERVICAL spine function
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髋膝关节置换围手术期血液管理的研究进展 预览
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作者 蔡立泉 胡舒 +2 位作者 代曹阳 郭现辉 廖威明 《中华关节外科杂志(电子版)》 CAS CSCD 2019年第2期220-224,共5页
骨关节炎是骨关节方面常见疾病,而髋膝关节置换术是治疗终末期骨关节炎的有效方法。由于髋膝关节置换围手术期贫血发生率高和出血量大,故安全、有效的血液管理有助于加快患者康复进程。目前髋膝关节置换血液管理贯穿于围手术期各个环节... 骨关节炎是骨关节方面常见疾病,而髋膝关节置换术是治疗终末期骨关节炎的有效方法。由于髋膝关节置换围手术期贫血发生率高和出血量大,故安全、有效的血液管理有助于加快患者康复进程。目前髋膝关节置换血液管理贯穿于围手术期各个环节,大致为术前纠正贫血、术中控制出血和术后改善贫血,应根据患者具体病情变化采取相应方式,减少围手术期出血、贫血及输血发生率,加快患者康复进程。本文通过分析、总结髋膝关节置换围手术期血液管理方面相关国内、外文献,综述髋膝关节置换围手术期血液管理研究进展。 展开更多
关键词 骨关节炎 关节成形术 置换 关节成形术 置换 血液
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