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Impact of the Horizontal Heat Flux in the Mixed Layer on an Extreme Heat Event in North China:A Case Study 预览
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作者 Ying NA Riyu LU +2 位作者 Bing LU Min CHEN Shiguang MIAO 《大气科学进展:英文版》 SCIE CAS CSCD 2019年第2期133-142,共10页
Extreme heat over the North China Plain is typically induced by anomalous descending flows associated with anticyclonic circulation anomalies.However,an extreme heat event that happened in the North China Plain region... Extreme heat over the North China Plain is typically induced by anomalous descending flows associated with anticyclonic circulation anomalies.However,an extreme heat event that happened in the North China Plain region on 12–13 July 2015,with maximum temperature higher than 40℃at some stations,was characterized by only a weak simultaneous appearance of an anomalous anticyclone and descending flow,suggesting that some other factor(s)may have induced this heat event.In this study,we used the forecast data produced by the Beijing Rapid Updated Cycling operational forecast system,which predicted the heat event well,to investigate the formation mechanism of this extreme heat event.We calculated the cumulative heat in the mixed-layer air column of North China to represent the change in surface air temperature.The cumulative heat was composed of sensible heat flux from the ground surface and the horizontal heat flux convergence.The results indicated that the horizontal heat flux in the mixed layer played a crucial role in the temporal and spatial distribution of high temperatures.The horizontal heat flux was found to be induced by distinct distributions of air temperatures and horizontal winds at low levels during the two days,implying a complexity of the low-level atmosphere in causing the extreme heat. 展开更多
关键词 EXTREME HEAT North China Plain HORIZONTAL HEAT FLUX sensible HEAT FLUX WARM advection
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Major applications of heat pipe and its advances coupled with sorption system:a review
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作者 Yang YU Guoliang AN Liwei WANG 《能源前沿:英文版》 CSCD 2019年第1期172-184,共13页
Heat pipe utilizes continuous phase change process within a small temperature drop to achieve high thermal conductivity.For decades,heat pipes coupled with novel emerging technologies and methods(using nanofluids and ... Heat pipe utilizes continuous phase change process within a small temperature drop to achieve high thermal conductivity.For decades,heat pipes coupled with novel emerging technologies and methods(using nanofluids and self-rewetting fluids)have been highly appreciated,along with which a number of advances have taken place.In addition to some typical applications of themial control and heat recovery,the heat pipe technology combined with the sorption technology could efficiently improve the heat and mass transfer performance of sorption systems for heating,cooling and cogeneration.However,almost all existing studies on this combination or integration have not concentrated on the principle of the sorption technology with acting as the heat pipe technology for continuous heat transfer.This paper presents an overview of the emerging working fluids,the major applications of heat pipe,and the advances in heat pipe type sorption system.Besides,the ongoing and perspectives of the solid sorption heat pipe are presented,expecting to serve as useful guides for further investigations and new research potentials. 展开更多
关键词 HEAT PIPE SORPTION SYSTEM HEAT transfer solid SORPTION HEAT PIPE
Overexpression of HSP27 and HSP70 is associated with decreased survival among patients with esophageal adenocarcinoma 预览
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作者 Henna K Soerstrom Juha T Kauppi +4 位作者 Niku Oksala Timo Paavonen Leena Krogerus Jari Rasanen Tuomo Rantanen 《世界临床病例杂志》 2019年第3期260-269,共10页
BACKGROUND Overexpression of heat shock proteins(HSPs)is associated with several malignancies and contributes to the development,progression,and metastasis of cancer,in addition to the inhibition of cellular death.In ... BACKGROUND Overexpression of heat shock proteins(HSPs)is associated with several malignancies and contributes to the development,progression,and metastasis of cancer,in addition to the inhibition of cellular death.In recent years,there has been active research into using HSP inhibitors in several malignancies.Due to the poor prognosis of esophageal adenocarcinoma(EAC),it would be valuable to find new biomarkers for the development of cancer treatments.AIM To evaluate the expressions of HSP27 and HSP70 and their effect on survival in EAC.METHODS Immunohistochemical analyses and evaluations of HSP27 and HSP70 expression were performed on all available samples from 93 patients diagnosed with EAC between 1990 and 2007 at two university hospitals.Fifteen cases with Barrett’s metaplasia and 5 control cases from the same patient population were included in the analysis.HSP expression was quantitatively assessed and classified as high or low.Kaplan-Meier analyses and Cox regression models adjusting for age and sex as well as tumor site,stage,and grade were used to evaluate the effect on survival.RESULTS Tumor stage and surgical treatment were the main prognostic factors.High HSP27 expression in cancer cases was a strong negative predictive factor,with a mean survival of 23 mo compared to the 49 mo in cases with a low expression(P=0.018).The results were similar for HSP70,with a poorer survival of 17 mo in cases with high HSP70 expression,in contrast to 40 mo(P=0.006)in cases with a low expression.A Cox regression survival analysis was performed,adjusting for possible confounding factors,and higher HSP27 and HSP70 expressions remained an independent negative prognostic factor.The HSPs’correlation with survival was not affected by cancer treatments.When the analysis was adjusted for all factors,the odds ratios for HSP27 and HSP70 were 3.3(CI:1.6–6.6,P=0.001)and 2.2(CI:1.2–3.9,P=0.02),respectively.CONCLUSION HSP27 and HSP70 overexpression is associated with poor survival in EAC,which is,to the best of our knowledge, 展开更多
关键词 Esophageal adenocarcinoma HEAT shock proteins HEAT shock PROTEIN 27 HEAT shock PROTEIN 70 OVEREXPRESSION SURVIVAL
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Reversible and irreversible heat generation of NCA/Si–C pouch cell during electrochemical energy-storage process 预览
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作者 Ying Bai Limin Li +8 位作者 Yu Li Guanghai Chen Huichun Zhao Zhaohua Wang Chuan Wu Hongyun Ma Xinquan Wang Hongyue Cui Jiang Zhou 《能源化学:英文版》 SCIE EI CAS CSCD 2019年第2期95-102,共8页
To meet the requirements of electronic vehicles(EVs) and hybrid electric vehicles(HEVs),the high energy density Li Ni0.8 Co0.15 Al0.05 O2(NCA) cathode and Si–C anode have attracted more attention.Here we report the t... To meet the requirements of electronic vehicles(EVs) and hybrid electric vehicles(HEVs),the high energy density Li Ni0.8 Co0.15 Al0.05 O2(NCA) cathode and Si–C anode have attracted more attention.Here we report the thermal behaviors of NCA/Si–C pouch cell during the charge/discharge processes at different current densities.The total heat generations are derived from the surface temperature change during electrochemical Li+insertion/extraction in adiabatic surrounding.The reversible heat is determined by the entropic coefficients,which are related with open-circuit voltage at different temperatures;while the irreversible heat is determined by the internal resistance,which can be obtained via V–I characteristic,electrochemical impedance spectroscopy and hybrid pulse power characterization(HPPC).During the electrochemical process,the reversible heat contributes less than 10% to total heat generation;and the heat generated in charge process is less than that in discharge process.The results of thermal behaviors analyses are conducive to understanding the safety management and paving the way for building a reliable thermal model of high energy density lithium ion battery. 展开更多
关键词 HEAT generation Internal resistance REVERSIBLE HEAT IRREVERSIBLE HEAT POUCH CELL
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日光温室灌溉水与周围环境的热量迁移特性
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作者 苏冬阳 胡婧娟 《北方园艺》 CAS 北大核心 2019年第8期67-72,共6页
为探求越冬期日光温室灌溉水在升温过程中热量迁移规律,以山西省吕梁市离石区日光温室为研究对象,对日光温室内灌溉水水温、地温、气温等数据进行了跟踪观测;利用传热学的理论和方法,研究了灌溉水与周围环境的热量交换情况。结果表明:土... 为探求越冬期日光温室灌溉水在升温过程中热量迁移规律,以山西省吕梁市离石区日光温室为研究对象,对日光温室内灌溉水水温、地温、气温等数据进行了跟踪观测;利用传热学的理论和方法,研究了灌溉水与周围环境的热量交换情况。结果表明:土-水之间的热量交换方向在大部分时间内由土壤传递向灌溉水,48h内土壤向灌溉水的传热量由表层到深层分别为3.57、13.21、7.50、7.02、5.08、4.54、22.40 MJ,共计63.32 MJ;气-水之间的热量交换方向始终由空气传递向灌溉水,48h内空气向灌溉水的传热量为17.49 MJ;并根据土-水、气-水之间的热量迁移特性,提出增大升温池侧面积、早晨升温池池顶覆盖保温材料、中午增加通过换气量等科学、快速的提升灌溉水水温的措施。研究结果可丰富越冬期日光温室灌溉水管理技术。 展开更多
关键词 日光温室 灌溉水 热量 对流换热 辐射传热
航天炉真空闪蒸汽余热供热利用技术改造实践 预览
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作者 邓金泉 霍跃光 《煤化工》 CAS 2019年第3期44-46,共3页
航天炉在运行过程中,渣水闪蒸系统的真空闪蒸汽被循环水冷凝,热量没有利用,为利用这部分高品位热量,对真空闪蒸汽余热进行了利用改造。介绍了真空闪蒸汽余热供热系统的工艺改造方案及改造后的工艺流程,分析了航天炉余热供热改造的创新... 航天炉在运行过程中,渣水闪蒸系统的真空闪蒸汽被循环水冷凝,热量没有利用,为利用这部分高品位热量,对真空闪蒸汽余热进行了利用改造。介绍了真空闪蒸汽余热供热系统的工艺改造方案及改造后的工艺流程,分析了航天炉余热供热改造的创新点。生产运行表明,某公司改造后的余热供热系统,供水温度在70℃~80℃,供暖季回收热量22.75GJ,节煤1.75万t,减排CO21.6万t、SO260t。 展开更多
关键词 航天炉 真空闪蒸汽 热量 真空闪蒸冷凝器 余热供热
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Technical and Economic Aspects and Experience from 6 Years of Operating the Technology Using the Waste Heat from the Exhaust Gases of Heat Sources and 3 Years of Operating a Heating Plant in an Autonomous, Island Regime 预览
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作者 Imrich Discantiny 《地质资源与工程:英文版》 2019年第2期39-44,共6页
This article is focused on technical and economic evaluation of more than 6-years experiences of operating the Waste Heat Recovery technology—the manner and system of flue gas processing generated in the combustion p... This article is focused on technical and economic evaluation of more than 6-years experiences of operating the Waste Heat Recovery technology—the manner and system of flue gas processing generated in the combustion process in heat & power plants, cogeneration units, etc., which burn the gaseous fuel, primarily natural gas, or methane, biogas, geothermal gas, or other gaseous mixtures containing hydrogen. The solution proposes a more effective and non-traditional use of gaseous fuel for heating, the flue gases of which are processed in order to extract additional utilisable heat, with potential elimination of CO2 from them. Deploying of the heating plant in an island regime (OFF-GRID) enables definition of the benefits brought by the 3 years of operational experience and presents visions for the future offering the possibility to utilise the support energy services at the municipal as well as regional level. 展开更多
关键词 NATURAL GAS (NG) liquefied NATURAL GAS (LNG) liquefied propane GAS (LPG) combined HEAT & power (CHP) renewable energy sources (RES) waste HEAT recovery (WHR) international GAS union (IGU)
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Improving the performance of a thermoelectric power system using a flat-plate heat pipe
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作者 Suchen Wu Yiwen Ding +1 位作者 Chengbin Zhang Dehao Xu 《中国化学工程学报:英文版》 SCIE EI CAS CSCD 2019年第1期44-53,共10页
A gravitational flat-plate heat pipe is designed and fabricated in this paper to serve as a heat spreader to diffuse the local heat source to the hot side of the thermoelectric power module.Based on this,an experiment... A gravitational flat-plate heat pipe is designed and fabricated in this paper to serve as a heat spreader to diffuse the local heat source to the hot side of the thermoelectric power module.Based on this,an experimental test for the thermoelectric power generation system is conducted to study the influences of the heat spreader on the temperature uniformity and power generation performance when exposing to a local heat source.In addition,the effects of the heating power,inclination angle,and local heat source size on the power generation performance of the thermoelectric power module using a flat-plate heat pipe as a heat spreader are examined and compared with that using a metal plate.The results indicate that the gravitational flat-plate heat pipe has considerable advantages over the metal plate in the temperature uniformity.The superiority of temperature uniformity in the improvement of power generation performance for the thermoelectric power system using a heat pipe is demonstrated.Particularly,the heat pipe shows good adaptability to placement mode and the local heat source size,which is beneficial to the application in the thermoelectric power generation. 展开更多
关键词 THERMOELECTRIC HEAT pipe HEAT SPREADER Power generation
高温和干旱对水稻的影响及其机制的研究进展 预览
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作者 段骅 佟卉 +3 位作者 刘燕清 许庆芬 马骏 王春敏 《中国水稻科学》 CAS CSCD 北大核心 2019年第3期206-218,共13页
高温和干旱是影响水稻生长、发育、产量和品质的两个最重要的环境因子,全面理解高温和干旱胁迫对评价气候变化对水稻生产的影响至关重要。概述了高温、干旱及其复合胁迫对水稻生长发育、产量形成和稻米品质的影响;从光合作用、抗氧化系... 高温和干旱是影响水稻生长、发育、产量和品质的两个最重要的环境因子,全面理解高温和干旱胁迫对评价气候变化对水稻生产的影响至关重要。概述了高温、干旱及其复合胁迫对水稻生长发育、产量形成和稻米品质的影响;从光合作用、抗氧化系统、内源激素、蔗糖-淀粉代谢途径关键酶活性、分子机制等方面阐述其生理机制;提出减轻水稻高温干旱胁迫的调控措施;对未来深入开展水稻高温干旱逆境的研究提出建议。 展开更多
关键词 水稻 高温 干旱 高温干旱复合胁迫 产量 品质 生理机制
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Effect of heat input on austenite microstructural evolution of simulated heat affected zone in 2205 duplex stainless steel
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作者 Tian-hai Wu Jian-jun Wang +3 位作者 Hua-bing Li Zhou-hua Jiang Chun-ming Liu Hong-yang Zhang 《钢铁研究学报:英文版》 SCIE EI CAS CSCD 2019年第5期435-441,共7页
The effect of simulated welding thermal cycle on the microstructure and impact toughness of heat affected zone (HAZ) in 2205 duplex stainless steel was investigated by optical microscopy, scanning electron microscopy,... The effect of simulated welding thermal cycle on the microstructure and impact toughness of heat affected zone (HAZ) in 2205 duplex stainless steel was investigated by optical microscopy, scanning electron microscopy, transmission electron microscopy and room temperature impact test. The results show that the morphology and volume fraction of austenite change greatly with heat input. The amount of residual austenite and grain boundary austenite (GBA) decreases while Widmanstatten austenite (WA) laths and intergranular austenite increase with the increase in heat input. Only the fine equiaxed austenite exists in the HAZ when the heat input is increased up to 61.8 kJ/cm. WA laths nucleate initially either at the ferrite and GBA phase boundaries or directly in ferrite grains and begin to decompose into diamond-shaped austenite with the heat input larger than 25.2 kJ/cm. The impact toughness shows a non-monotonic variation, which is related to the increase in austenite fraction and the formation and the decomposition of WA laths. 展开更多
关键词 2205 duplex stainless steel SIMULATED HEAT affected zone HEAT input Widmanstatten AUSTENITE Impact toughness
“因毒生热”——毒热理论体系的构建与发展
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作者 周琪 夏士林 +4 位作者 刘建均 庞敏 于睿 尚东 白长川 《中华中医药学刊》 CAS 北大核心 2019年第7期1702-1705,共4页
通过阐述中医学毒与热的含义、毒热理论的形成与发展,毒热物理、生物、化学的演变过程,探讨毒热的来源、病因病机。毒热比热毒的范围更广,毒、热可互为因果,互相转化;其病因为因毒而热,病机或为玄府闭塞,寒郁化热;或伏邪蕴蓄,化毒生热;... 通过阐述中医学毒与热的含义、毒热理论的形成与发展,毒热物理、生物、化学的演变过程,探讨毒热的来源、病因病机。毒热比热毒的范围更广,毒、热可互为因果,互相转化;其病因为因毒而热,病机或为玄府闭塞,寒郁化热;或伏邪蕴蓄,化毒生热;或杂气瘟疫,感毒化热;或毒邪内生,热发于外。中医"毒热"理论与毒热的现代生物学研究彼此深度融合,毒热理论可用于理解指导治疗现代临床疾病。临床实践中,不应将西医炎性疾病同中医的"热毒"相等同,可将其放在中医"毒热"的理论体系框架中,根据毒热具体的病因病机,审证论治。 展开更多
关键词 毒热理论
The vertical heat transport of internal solitary waves over the continental slope in the northern South China Sea 预览
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作者 Changrong Liang Xiaodong Shang Guiying Chen 《海洋学报:英文版》 SCIE CAS CSCD 2019年第3期36-44,共9页
An integrated analysis of internal solitary wave(ISW) observations obtained from two moorings over the continental slope in the northern South China Sea(SCS) leads to an assessment of the vertical heat transport of th... An integrated analysis of internal solitary wave(ISW) observations obtained from two moorings over the continental slope in the northern South China Sea(SCS) leads to an assessment of the vertical heat transport of the ISWs. The clusters of ISW packets are phase-locked to the fortnightly cycle of the semidiurnal tide. The ISWs appear during large semidiurnal tides, and there is a period of 5–6 d when no ISWs are observed. The effect of the ISWs on the continental slope heat budget is observed. The ISWs can modify a local temperature field in which the temperature in the upper layer can be changed by O(100) °C after the ISWs passed the mooring. Both ISWinduced diffusion and ISW-induced advection contribute to the temperature variation. The estimates imply an average vertical heat flux of 0.01 to 0.1 MW/m~2 in the ISWs in the upper 500 m of the water column. The vertical heat transport ranges from 0.56 to 2.83 GJ/m~2 with a mean value of 1.63 GJ/m~2. The observations suggest that the vertical heat transport is proportional to the maximum vertical displacement. 展开更多
关键词 internal SOLITARY wave VERTICAL HEAT transport temperature variation DIFFUSION advection VERTICAL HEAT FLUX
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Quantifying the non-conservative production of potential temperature over the past 22000 years 预览
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作者 ZHANG Cunjie HAN Xueshuang LIN Xiaopei 《海洋湖沼学报(英文)》 SCIE CAS CSCD 2019年第2期410-422,共13页
The energy budgets of the ocean play a crucial role in the analysis of climate change. Potential temperature is traditionally used as a conservative quantity to express variations associated with “heat” in oceanogra... The energy budgets of the ocean play a crucial role in the analysis of climate change. Potential temperature is traditionally used as a conservative quantity to express variations associated with “heat” in oceanography, such as the heat content and heat transport. However, potential temperature is usually not conserved during turbulent mixing, so the use of conservative temperature is more accurate. Based on climatological simulations under the modern and Last Glacial Maximum (LGM;~21 ka;ka=thousand years ago), as well as a transient climate simulation of the past 22 000 years, we quantify the errors induced by the neglect of the non-conservation of potential temperature in paleo-climate research for the first time. The temperature error reaches 0.9℃ near the coasts aff ected by river discharges but is much smaller in the open oceans, typically 0.03°C above the main thermocline and less than 0.01℃ elsewhere. The error of the ocean heat content (OHC) is roughly 3×10^22 J and is relatively steady over the past 22 000 years. However, the OHC increases to six times the original value during the last glacial termination from 20 ka to 7 ka. As a result, the relative OHC error decreases from 1.2% in the LGM climate to 0.14% in the modern climate. The error of the ocean meridional heat transport (OMHT) is generally smaller than 0.005 PW (1 PW=10 15 W), with very small temporal variations (typically 0.000 4 PW), and induces a relative OMHT error of typically 0.3% over the past 22 000 years. Therefore, the neglect of the non-conservation of potential temperature induces a relative error of generally less than 1% in the analyses of basin-scale climate variations. 展开更多
关键词 CONSERVATIVE TEMPERATURE potential TEMPERATURE OCEAN HEAT content OCEAN HEAT transport PALEOCLIMATE
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Surface-to-bed heat transfer for high-density particles in conical spouted and spout–fluid beds
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作者 Onur Yaman Gorkem Kulaha Murat Koksalb 《中国颗粒学报:英文版》 SCIE EI CAS CSCD 2019年第1期35-47,共13页
Bed-to-surface heat transfer experiments from a vertically submerged cylindrical surface were conducted in laboratory-scale (Dc = 25 cm) conical spouted and spout–fluid beds at two different conical angles (31° ... Bed-to-surface heat transfer experiments from a vertically submerged cylindrical surface were conducted in laboratory-scale (Dc = 25 cm) conical spouted and spout–fluid beds at two different conical angles (31° and 66°) in the high particle density range (2500 kg/m3 ≤ρp ≤ 6000 kg/m3). The effects of the bed design parameters (conical angle and inlet diameter of spouting gas entrance) and operating conditions (static bed height, particle size, density, and spouting and fluidization gas flow rates) on the heat transfer characteristics were investigated in detail. The heat transfer coefficients were shown to be dependent on the density and size of the particles. The minimum stable spouting velocities of the denser and larger particles were higher, which led to higher operational spouting velocities and thereby resulted in higher heat transfer coefficients. The positive effect of increasing the particle diameter on heat transfer was more pronounced in the spout and at the spout–annulus interface, whereas this effect was diminished in the annulus region. The heat transfer coefficient increased with increasing spouting gas velocity up to 1.0Ums–1.1Ums, beyond which no significant change was observed regardless of the particle type. The heat transfer coefficient in the annulus decreased with increasing conical angle because of reduced particle circulation. The spout–fluid operation increased the heat transfer coefficient by a maximum of 10% at the expense of a significant increase of the total gas flow rate. This result was attributed to the inability of the fluidizing gas to penetrate the annulus. An empirical correlation for the average heat transfer coefficient in the annulus was also proposed based on the data obtained in this work. 展开更多
关键词 Conical spouted BED Spout–fluid BED Bed-to-surface HEAT TRANSFER Submerged HEAT TRANSFER SURFACE
Single-Reheating or Double-Reheating,Which is Better for S-CO2 Coal Fired Power Generation System?
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作者 SUN Enhui XU Jinliang +2 位作者 HU Han YAN Chenshuai LIU Chao 《热科学学报:英文版》 SCIE EI CAS CSCD 2019年第3期431-441,共11页
The objective of this paper is to provide the optimal choice of single-reheating or double-reheating when considering residual flue gas heat in S-CO2 coal fired power system.The cascade utilization of flue gas energy ... The objective of this paper is to provide the optimal choice of single-reheating or double-reheating when considering residual flue gas heat in S-CO2 coal fired power system.The cascade utilization of flue gas energy includes three temperature levels,with high and low temperature ranges of flue gas heat extracted by S-CO2 cycle and air preheater,respectively.Two methods are proposed to absorb residual flue gas heat Qre in middle temperature range.Both methods shall decrease CO2 temperature entering the boiler T4 and increase secondary air temperature Tsec air,whose maximum value is deduced based on energy conservation in air preheater.The system is analyzed incorporating thermodynamics,boiler pressure drop and energy distribution.It is shown that at a given main vapor temperature T5,the main vapor pressure P5 can be adjusted to a value so that Qre is completely eliminated,which is called the main vapor pressure adjustment method.For this method,single-reheating is only available for higher main vapor temperatures.The power generation efficiency for single-reheating is obviously higher than double-reheating.If residual flue gas heat does exist,a flue gas heater FGC is integrated with S-CO2 cycle,which is called the FGC method.Both single-reheating and double-reheating share similar power generation efficiency,but single-reheating creates less residual flue gas heat.We conclude that single-reheating is preferable,and the pressure adjustment method achieves obviously higher power generation efficiency than the FGC method. 展开更多
关键词 S-CO2 COAL fired power system thermodynamics HEAT transfer REHEATING residual FLUE gas HEAT
Variations of Surface Heat Fluxes over the Tibetan Plateau before and after the Onset of the South Asian Summer Monsoon during 1979-2016
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作者 Yizhe HAN Weiqiang MA +1 位作者 Yaoming MA Cuiyan SUN 《气象学报:英文版》 SCIE CSCD 2019年第3期491-500,共10页
As the "Third Pole of the World," the Tibetan Plateau (TP) is an important thermal forcing to the South Asian summer monsoon (ASM) and even the global atmospheric circulation. In this paper, surface heat flu... As the "Third Pole of the World," the Tibetan Plateau (TP) is an important thermal forcing to the South Asian summer monsoon (ASM) and even the global atmospheric circulation. In this paper, surface heat fluxes from the ERA-Interim reanalysis data during March-October of 1979-2016 in the TP and its surrounding areas are examined and analyzed. The results are as follows.(1) From March to May (before the ASM onset), the main body of the TP is dominated by sensible heat flux, which increases rapidly with high (low) values in the west (east), while the change of latent heat flux is small but it increases with time.(2) From June to August (after the ASM onset), sensible heat flux over the TP decreases, while latent heat flux increases rapidly with high (low) values in the east (west).(3) From September to October (after the ASM withdrawal), sensible and latent heat fluxes are comparable to each other in strength, again with high (low) sensible heat flux in the west (east).(4) During 1979-2016, surface sensible heat flux in the whole TP shows a slightly downward trend, while latent heat flux shows an increasing trend. Specifically, in the western TP, sensible (latent) heat flux shows a weak decreasing (an increasing) trend;while in the eastern TP, sensible (latent) heat flux decreases (increases obviously). These variations are consistent with the observed warming and moistening in the TP region. The above results are useful for further analysis of the change of atmospheric heat sources and surface heat fluxes over the TP based on the data from the Third Tibetan Plateau Atmospheric Science Experiment (TIPEX-Ⅲ). 展开更多
关键词 TIBETAN Plateau (TP) REANALYSIS data sensible HEAT FLUX LATENT HEAT FLUX
Dorsomorphin induces cancer cell apoptosis and sensitizes cancer cells to HSP90 and proteasome inhibitors by reducing nuclear heat shock factor 1 levels 预览
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作者 Na Li Ting Wang +12 位作者 Zongmeng Li Xiaoli Ye Bo Deng Shu Zhuo Pengle Yao Mengmei Yang Hong Mei Xiaofang Chen Tengfei Zhu Shiting Chen Hui Wang Jiming Wang Yingying Le 《癌症生物学与医学:英文版》 CAS CSCD 2019年第2期220-233,共14页
Objective: Heat shock factor 1(HSF1), a transcriptional regulator of heat shock proteins(HSPs), is an attractive therapeutic target for cancer. However, only a few HSF1 inhibitors have been identified so far.Methods: ... Objective: Heat shock factor 1(HSF1), a transcriptional regulator of heat shock proteins(HSPs), is an attractive therapeutic target for cancer. However, only a few HSF1 inhibitors have been identified so far.Methods: The mRNA and protein levels of HSF1, HSPs, cleaved PARP, and phosphorylated HSF1 were examined by real-time PCR and Western blot. Forced expression, RNA interference, and immunofluorescence assay were used for mechanistic studies.Cell viability and apoptosis were measured by WST-8 assay and flow cytometry, respectively. Xenograft studies were performed in nude mice to evaluate the effect of dorsomorphin and an HSP90 inhibitor on tumor growth.Results: Dorsomorphin suppressed multiple stimuli-induced and constitutive HSPs expression in cancer cells. Mechanistic studies revealed that dorsomorphin reduced heat-induced HSP expression independent of adenosine monophosphate activated protein kinase. Dorsomorphin reduced heat-stimulated HSF1 Ser320 phosphorylation and nuclear translocation, as well as resting nuclear HSF1 levels in cancer cells. Dorsomorphin induced cancer cell apoptosis by inhibiting HSF1 expression. A structure-activity study revealed that the 4-pyridyl at the 3-site of the pyrazolo [1, 5-a]pyrimidine ring is critical for the anti-HSF1 activities of dorsomorphin. Dorsomorphin sensitized cancer cells to HSP90 and proteasome inhibitors and inhibited HSP70 expression induced by these inhibitors in vitro. In tumor-bearing nude mice, dorsomorphin enhanced HSP90 inhibitor-induced cancer cell apoptosis, tumor growth inhibition, and HSP70 expression.Conclusions: Dorsomorphin is an HSF1 inhibitor. It induces cancer cell apoptosis, sensitizes cancer cells to both HSP90 and proteasome inhibitors, and suppresses HSP upregulation by these drugs, which may prevent the development of drug resistance.Hence, dorsomorphin and its derivates may serve as potential precursors for developing drugs against cancer. 展开更多
关键词 Dorsomorphin HEAT shock factor 1 HEAT shock protein APOPTOSIS cancer
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Research on the Heat Transfer Characteristics of a Loop Heat Pipe Used as Mainline Heat Transfer Mode for Spacecraft
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作者 WANG Lu MIAO Jianyin +4 位作者 GONG Mingming ZHOU Qiangu LIU Changu ZHANG Hongxing FAN Hanlin 《热科学学报:英文版》 SCIE EI CAS CSCD 2019年第4期736-744,共9页
An experimental research is conducted on the heat transfer characteristics of a loop heat pipe(LHP)used in the"mainline"heat transfer mode for spacecraft platform thermal control.The heat from multiple instr... An experimental research is conducted on the heat transfer characteristics of a loop heat pipe(LHP)used in the"mainline"heat transfer mode for spacecraft platform thermal control.The heat from multiple instruments scattered in different locations is collected by thermal control techniques such as axially grooved heat pipes and then transmitted to the radiant surface for dissipation through the LHP in an unified way.The research contents include the start-up characteristics,the operational stability characteristics,the operational blocking characteristics,the continuous blocking characteristics,the heat transfer capability,the thermal resistance,and the dynamic response characteristics under the change of the heat sink temperature.The results show that the higher the auxiliary starting power is,the easier it is to start the LHP;the higher the input power of the thermoelectric cooler is,the more beneficial it is to speed up the stabilization of the vapor-liquid interface in the condenser;the higher the blocking power,the shorter the blocking time of the LHP;the LHP can be operated stably within the heat sink temperature alteration process;the heat transfer ability is higher than 500 W with a systematic thermal resistance of 0.037℃/W. 展开更多
关键词 LHP mainline HEAT TRANSFER MODE HEAT TRANSFER characteristics
Estimation of Oceanic Heat Flux Under Sea Ice in the Arctic Ocean 预览
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作者 LIN Long ZHAO Jinping 《中国海洋大学学报:英文版》 SCIE CAS CSCD 2019年第3期605-614,共10页
Oceanic heat flux(Fw) is the vertical heat flux that is transmitted to the base of sea ice. It is the main source of sea ice bottom melting. The residual method was adopted to study oceanic heat flux under sea ice. Th... Oceanic heat flux(Fw) is the vertical heat flux that is transmitted to the base of sea ice. It is the main source of sea ice bottom melting. The residual method was adopted to study oceanic heat flux under sea ice. The data acquired by 28 ice mass balance buoys(IMBs) deployed over the period of 2004 to 2013 in the Arctic Ocean were used. Fw values presented striking seasonal and spatial variations. The average summer Fw values for the Canada Basin, Transpolar Drift, and Multiyear Ice area were 16.8, 7.7, and 5.9 W m^-2, respectively. The mean summer F-w for the whole Arctic was 10.1 W m^-2, which was equivalent to a bottom melt of 0.4 m. Fw showed an autumn peak in November in the presence of the near-surface temperature maximum(NSTM). The average Fw for October to December was 3.7 W m^-2. And the average Fw for January to March was 1.0 W m^-2, which was approximately one third of the average Fw in the presence of NSTM. The summer Fw was almost wholly attributed to the incident solar radiation that enters the upper ocean through leads and the open water. Fw calculated through the residual method using IMB data was compared with that calculated through the parameterization method using Autonomous Ocean Flux Buoy data. The results revealed that the Fw provided by the two methods were consistent when the sea ice concentration exceeded 70% and mixing layer temperature departure from freezing point was less than 0.15℃. Otherwise, the Fw yielded by the residual method was approximately one third smaller than that provided by the parameterization method. 展开更多
关键词 ARCTIC OCEAN OCEANIC HEAT flux RESIDUAL method NSTM HEAT release
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Optimization Potentials for the Waste Heat Recovery of a Gas-Steam Combined Cycle Power Plant Based on Absorption Heat Pump
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作者 ZHANG Hongsheng ZHAO Hongbin +1 位作者 LI Zhenlin HU Eric 《热科学学报:英文版》 SCIE EI CAS CSCD 2019年第2期283-293,共11页
A new waste heat recovery system is presented to recover exhausted steam waste heat from the steam turbine by absorption heat pump(AHP) in a gas-steam combined cycle(GSCC) power plant. The system can decrease energy c... A new waste heat recovery system is presented to recover exhausted steam waste heat from the steam turbine by absorption heat pump(AHP) in a gas-steam combined cycle(GSCC) power plant. The system can decrease energy consumption and further improve the energy utilization. The performance evaluation criteria are calculated, and exergy analysis for key components are implemented in terms of the energy and exergy analysis theory. Besides, the change of these criteria is also revealed before and after modification. The net power output approximately increases by 21738 kW, and equivalent coal consumption decreases by 5.58 g/kWh. A 1.81% and 1.92% increase in the thermal and exergy efficiency is respectively obtained in the new integrated system as the heating load is 401095 kJ at 100% condition. Meanwhile, the appropriate extraction parameters for heating have been also analyzed in the two systems. The proposed scheme can not only save energy consumption but also reduce emission and gain great economic benefit, which is proven to be a huge potential for practical application. 展开更多
关键词 combined CYCLE power plant absorption HEAT PUMP waste HEAT recovery evaluation CRITERIA EXERGY analysis
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