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通元针法对排卵障碍性不孕症患者妊娠成功率的影响 预览
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作者 张永宏 《上海针灸杂志》 2019年第5期520-524,共5页
目的观察通元针法对排卵障碍性不孕症患者妊娠成功率的影响。方法106例排卵障碍性不孕症患者,随机分为治疗组和对照组,每组53例。对照组给予西医促排卵治疗,治疗组在对照组基础上给予通元针法治疗。比较两组卵巢功能[卵泡刺激素(FSH)、... 目的观察通元针法对排卵障碍性不孕症患者妊娠成功率的影响。方法106例排卵障碍性不孕症患者,随机分为治疗组和对照组,每组53例。对照组给予西医促排卵治疗,治疗组在对照组基础上给予通元针法治疗。比较两组卵巢功能[卵泡刺激素(FSH)、黄体生成素(LH)、雌二醇(E2)]、子宫内膜厚度、排卵、妊娠情况。结果两组治疗后FSH、LH、E2明显高于治疗前(P<0.05),治疗组治疗后FSH、LH、E2明显高于对照组(P<0.05)。两组治疗1个疗程后、3个疗程后子宫内膜厚度明显高于治疗前(P<0.05),治疗组治疗1个疗程后、3个疗程后子宫内膜厚度明显高于对照组(P<0.05)。治疗组排卵率、妊娠成功率明显高于对照组,差异有统计学意义(P<0.05)。结论通元针法配合西医促排卵治疗可有效改善排卵障碍性不孕症患者卵巢功能、子宫内膜厚度,有利于促进患者排卵而提高妊娠成功率。 展开更多
关键词 针刺疗法 电针 通元针法 刺法 不育 女性 不孕症 卵巢疾病 排卵障碍
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Smoking, ACP<sub>1</sub>and Infertility in Subjects with Varicocele 预览
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作者 Anna Neri Maria Banci +2 位作者 Adalgisa Pietropolli Fulvia Gloria-Bottini Andrea Magrini 《健康(英文)》 2019年第10期1331-1337,共7页
Several studies suggest that smoking may have detrimental effect on seminal parameters and that genetic polymorphisms may influence this effect. In the present paper we have examined the relationship between ACP1 geno... Several studies suggest that smoking may have detrimental effect on seminal parameters and that genetic polymorphisms may influence this effect. In the present paper we have examined the relationship between ACP1 genotypes and the association of smoking and infertility in a sample of men with varicocele. 126 subjects with varicocele were studied. ACP1 genotype was determined by DNA analysis and statistical analyses were performed by SPSS software. In general there is a protective action of low activity *A/*B genotype against infertility that is much more marked in smokers than in non-smokers. If confirmed in other clinical settings, determinations of ACP1 genotype could have practical importance to evaluate the risk of infertility in smokers with varicocele. 展开更多
关键词 SMOKING ACP1 VARICOCELE INFERTILITY Genetic Polymorphism
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不孕不育人群淋球菌感染现状及耐药性分析 预览
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作者 胡坚 黄益飞 刘刚 《重庆医学》 CAS 2019年第10期1724-1725,1731共3页
目的了解不孕不育人群中淋球菌感染率及耐药现状。方法对2012年1月至2017年6月在中信湘雅生殖与遗传专科医院就诊的不孕不育患者生殖道分泌物标本进行淋球菌分离鉴定,鉴定为阳性菌株者进行药敏试验;药敏试验采用美国临床和实验室标准协... 目的了解不孕不育人群中淋球菌感染率及耐药现状。方法对2012年1月至2017年6月在中信湘雅生殖与遗传专科医院就诊的不孕不育患者生殖道分泌物标本进行淋球菌分离鉴定,鉴定为阳性菌株者进行药敏试验;药敏试验采用美国临床和实验室标准协会(CLSI)推荐的纸片扩散(K-B)法,药敏纸片选用5种常用抗菌药物。结果不孕不育人群淋球菌的感染率为0.05%,其中男性不育人群淋球菌感染率为0.03%,女性不孕人群淋球菌感染率为0.06%;分离鉴定的淋球菌菌株对5种抗菌药物的耐药性有明显的区别,菌株对四环素、青霉素和环丙沙星的耐药性比较高,对头孢曲松、大观霉素的灵敏度比较高。结论不孕不育人群中女性淋球菌感染率显著高于男性,第三代头孢菌素和大观霉素可作为淋病治疗的首选药物。 展开更多
关键词 不育 女(雌)性 不育 男(雄)性 淋球菌 感染率 抗菌药物 耐药性
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刘丽教授气滞血瘀型输卵管炎造模方法总结 预览
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作者 李楠 刘丽 《世界中西医结合杂志》 2019年第5期626-629,共4页
导师刘丽教授师从于龙江韩氏妇科,从医近30余年,擅长中西医结合治疗气滞血瘀型输卵管炎性不孕,经过多年理论研究与临床实践,根据病证结合理论,对气滞血瘀型输卵管炎模型建立颇有心得。导师造模方法为先用金黄色葡萄球菌注入到输卵管中... 导师刘丽教授师从于龙江韩氏妇科,从医近30余年,擅长中西医结合治疗气滞血瘀型输卵管炎性不孕,经过多年理论研究与临床实践,根据病证结合理论,对气滞血瘀型输卵管炎模型建立颇有心得。导师造模方法为先用金黄色葡萄球菌注入到输卵管中建立疾病模型,然后采用声、光、电等复合因素建立证型模型。目前中医研究疾病模型,大多很难病证相结合,文章通过对相关文献进行了总结论述,以期为同一疾病同一证候建立一个统一的造模方法和一个统一的评价体系。中医药从业人员,需要多角度、深入进行国际交流,不断完善自己的方法。 展开更多
关键词 不孕症 气滞血瘀 输卵管炎性不孕 病证结合 动物模型
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不明原因不孕病因与治疗 预览
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作者 徐晓旭 郁琦 《医学综述》 2019年第13期2643-2647,2653共6页
不明原因不孕是一种排除性诊断,目前尚无统一的标准。多种原因可导致不明原因不孕,如免疫因素、子宫及输卵管疾病、患者年龄以及子宫容受性等。不孕检查包括精液检查、排卵及黄体功能检查、输卵管检查等。目前该病的发病率正在随着诊断... 不明原因不孕是一种排除性诊断,目前尚无统一的标准。多种原因可导致不明原因不孕,如免疫因素、子宫及输卵管疾病、患者年龄以及子宫容受性等。不孕检查包括精液检查、排卵及黄体功能检查、输卵管检查等。目前该病的发病率正在随着诊断技术的提高而有下降的趋势。对于不明原因不孕可采用期待治疗、诱导排卵后指导同房、诱导排卵加宫腔内人工授精等,若经过上述治疗方法仍无法妊娠,可进行体外受精-胚胎移植。 展开更多
关键词 不孕症 不明原因不孕 腹腔镜 宫腔镜 体外受精-胚胎移植
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Effect of Follicular Fluid Lactoferrin Level on Oocytes Quality and Pregnancy Rate in Intracytoplasmic Sperm Injection Cycles 预览
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作者 Mohamed Hussein Mostafa Malames Mahmoud Faisal +1 位作者 Noha Refaat Mohamed Filsan Houssein Idle 《妇产科期刊(英文)》 2019年第6期745-754,共10页
Assessment of oocyte quality to avoid overproduction of embryos is now considered an important goal in ICSI cycles. Although in classic Intra Cytoplasmic Sperm Injection (ICSI) cycles selection is mainly done for embr... Assessment of oocyte quality to avoid overproduction of embryos is now considered an important goal in ICSI cycles. Although in classic Intra Cytoplasmic Sperm Injection (ICSI) cycles selection is mainly done for embryos and not for follicles. Follicular fluid and its contents representing the oocyte environment are now gaining more attention because not only of its crucial influence on oocyte developments but also due to easy isolation of follicular fluid with every case of ICSI. By its aspiration during ovum pick up (OPU). substances isolated from follicular fluid to assess oocyte quality were in the form of: hormones like, Follicle Stimulating Hormone (FSH), Luteinizing Hormone (LH), Anti-mullerian Hormon (AMH), Growth Hormone (GH) etc., growth factors like Insulin Like Growth Factor (ILGF), proteins and amino acids like Lactoferrin (LF) which is an iron-binding glycoprotein that was detected in follicular fluid and was thought to be related to good oocyte quality when present in high concentration. Objectives: The aim of this study was to detect the possible effect of follicular fluid lactoferrin on oocyte quality and hence pregnancy rate in ICSI cycles. Methods: Follicular fluid was obtained from 64 patients undergoing Intra-cytoplasmic sperm injection (ICSI) procedure in Ain Shams University Maternity Hospital. Follicular fluid (FF) was collected at the time of oocyte harvesting. The lactoferrin concentration in FF was assayed by ELISA. Results: The mean LF concentration in follicular fluid of the positive biochemical pregnancy group (0.63 ± 0.17 ng/mL) was not significantly higher than that in the negative biochemical pregnancy (0.61 ± 0.16 ng/mL). A positive correlation between a number of mature oocytes and lactoferrin concentration was not found (r.101). Conclusion: Lactoferrin level in follicular fluid does not correlate with oocytes quality or pregnancy rate. 展开更多
关键词 LACTOFERRIN INFERTILITY FOLLICULAR Fluid OOCYTE QUALITY
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Management of Infertility in Endometriosis by Operative Laparoscopy and Medical Therapy—Practiced at 3 Different Centres, from September 2005 to October 2007 预览
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作者 Pratibha Devabhaktuni Swathi Gogineni +1 位作者 Savitha Devi Yalamanchi Anuradha Katragadda 《妇产科期刊(英文)》 2019年第6期775-788,共14页
This is a prospective study conducted over a period of 2 years and 1 month (from September 2005 to October 2007). 60/117 (52.17%) patients who had laparoscopy for infertility at GMH had endometriosis. 60 patients oper... This is a prospective study conducted over a period of 2 years and 1 month (from September 2005 to October 2007). 60/117 (52.17%) patients who had laparoscopy for infertility at GMH had endometriosis. 60 patients operated for endometriosis at SHC and 40 patients managed at Anu Infertility Centre during the same period are also included in this study. All the 60 patients underwent operative laparoscopy for endometriosis. Adhesiolysis, electrocautery of surface endometriosis of the ovary, enucleation of endometriotic cyst, mobilization of ovary from uterus and pouch of Douglas and restoration of normal anatomy were carried out. Treatment interventions: Therapeutic hysteroscopy and laparoscopy, medical treatment by various ovulation induction protocols, monitoring by follicular sonography followed by pregnancy management were done in these women. Results: GMH—Seventeen 17 out of 18 coming for follow up conceived, 14 following ovulation induction and 3 after COH + IUI, by one year at GMH. SHC—14 out of 18 patients coming for follow up at the end of one year conceived, following ovulation induction 6, COH + IUI-3, IVF-3 and spontaneous 2. ANU—Out of 11 conceptions, COH + IUI resulted in 6, IVF in 4, spontaneous in 1—by one year. Pregnancy outcome: GMH: Ten delivered, Triplets in one, missed abortion two, emergency laparotomy in one. Pregnancy is continuing in 4. SHC: Eight patients delivered. Pregnancy is continuing in 4 patients. Ectopic-1, missed abortion-1. ANU: Five patients delivered. Pregnancy is continuing in 3 women, missed abortion-2, second trimester abruption-1. Discussion: The conception rate was 50% at the end of 6 months follow up <span s 展开更多
关键词 ENDOMETRIOSIS INFERTILITY CONCEPTIONS OVULATION INDUCTION
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Endometrial Preparation for Frozen Embryo Transfer by Supplemented Natural Cycle versus Hormone Replacement Cycle in Regularly Cycling Women 预览
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作者 Suzan Samir Elsharkawy Tamer Hanafy Mahmoud +1 位作者 Mervat Sheikh-Elarab Elsedeek Eman Monier Abd Elkader Amer 《妇产科期刊(英文)》 2019年第6期827-837,共11页
BACKGROUND: The first successful pregnancy from a frozen-thawed embryo transfer (FTET) was reported in 1983 and after more than three decades, significant changes have been introduced into clinical practice. OBJECTIVE... BACKGROUND: The first successful pregnancy from a frozen-thawed embryo transfer (FTET) was reported in 1983 and after more than three decades, significant changes have been introduced into clinical practice. OBJECTIVE: To compare endometrial preparation for frozen thawed embryo transfer (FTET) in supplemented natural cycle (NC) by hCG (human chorionic gonadotropin) versus HRT (hormonal replacement therapy) by estrogen and progesterone in regularly cycling women. METHODS: A prospective trial was conducted on 40 patients that were divided into two treatment groups. The first group underwent endometrial preparation by supplemented natural cycle by HCG, and the second group underwent endometrial preparation by HRT (estrogen and progesterone). RESULTS: No significant difference was revealed between the two groups regarding ongoing clinical pregnancy rate. CONCLUSION: This study concluded that there is no significant difference in clinical pregnancy rate between the two methods of endometrial preparation for frozen thawed embryo transfer;supplemented natural cycle by hCG or HRT by estrogen and progesterone, in regularly cycling women. 展开更多
关键词 INTRACYTOPLASMIC SPERM Injection (ICSI) INFERTILITY FROZEN Cycles
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Endometrial Necrosis Following B-Lynch Suture for Uterine Atony 预览
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作者 Wenying Li Wenzhi Qin 《妇产科期刊(英文)》 2019年第7期1032-1038,共7页
B-Lynch compression suturing was performed on a 30-year old primipara during emergency Cesarean section (CS). After CS, she developed a low-grade fever, a subinvolution and tenderness of the uterus, and a pronounced i... B-Lynch compression suturing was performed on a 30-year old primipara during emergency Cesarean section (CS). After CS, she developed a low-grade fever, a subinvolution and tenderness of the uterus, and a pronounced increase in the inflammatory markers. Antibiotics were altered according to bacterial cultures and drug sensitivity testing of the cervix. By 10 days postpartum, a diagnostic curettage was performed and released a foul-smelling liquid matter due to the substantial amount of heterogeneous material with gaseous echoes showed via ultrasonography. The inflammatory markers gradually returned to normal by 9 days post curettage. At 12-day post curettage, a foul-smelling purulent tissue was extruded spontaneously via the vagina and proved to be necrotic tissue on pathologic examination. Eighteen months after childbirth, the patient had not experienced a menstrual period or subsequent pregnancy and a small uterus without any evidence of an endometrium showed by ultrasonography. 展开更多
关键词 CESAREAN Section INFERTILITY POSTPARTUM Care POSTPARTUM Hemorrhage POSTPARTUM INFECTIONS
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The Effect of Balanced Hypocaloric Diet on the Anthropometric and Basic Metabolic Indicators in Infertile Women with Gluteofemoral Obesity 预览
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作者 Natalia V. Artymuk Natalia A. Sukhova +1 位作者 Olga A. Tachkova Moamar Al-Jefout 《妇产科期刊(英文)》 2019年第10期1325-1335,共11页
Purpose: To evaluate the effect of balanced hypocaloric diet therapy on the anthropometric and basic metabolic indicators in obese women with infertility. Methods: The follow up interventional clinical study included ... Purpose: To evaluate the effect of balanced hypocaloric diet therapy on the anthropometric and basic metabolic indicators in obese women with infertility. Methods: The follow up interventional clinical study included 23 infertile women in reproductive age with grade I gluteofemoral obesity. All patients have prescribed a balanced hypocaloric diet (1200 kcal/day), underwent exercise and behavioral therapy. Before and after 12-month treatment, an anthropometric study was conducted, determining the level of metabolic and hormonal indicators. Results: The total final number of study participants was 20 patients. A decrease in body weight was achieved in 87% of patients from 4 to 24 kg, on the average, by 10.58 ± 5.70 kg, there was also a decrease in BMI from 32.53 ± 1.40 to 28.55 ± 2.50 kg/m2 (p 0.001). The decrease in body weight was accompanied by a statistically significant decrease in leptin levels (p 0.001), E1 (p = 0.049), E2 (p = 0.032), fasting glucose (p 0.001), HOMA-IR (p = 0.002), cholesterol (p < 0.001), TG (p = 0.004), LDL-C (p = 0.001), atherogenic index of plasma (p <0.001) and an increase in progesterone levels (p = 0.030). Ovulatory menstrual cycles were resumed in all women (p = 0.007) and pregnancy occurred within a year in 1 patient. Conclusion: The implementation of a hypocaloric diet for 12 months in infertile women with first-degree obesity helps to normalize metabolic and hormonal indicators, reduces body weight and restores ovulatory menstrual cycle in all patients. 展开更多
关键词 OBESITY REPRODUCTIVE Age INFERTILITY Diet Therapy ANOVULATION
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不孕症患者卵巢储备功能下降的影响因素分析 预览
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作者 李维芝 《世界复合医学》 2019年第1期157-159,共3页
目的探讨不孕症患者卵巢储备功能下降(DOR)的系列影响因素,以为不孕症防治工作的顺利开展奠定基础。方法选择该院2016年11月-2018年5月收治的62例DOR不孕症患者作为观察组;同时间段选择62名健康女性作为对照组;针对不孕症患者表现出卵... 目的探讨不孕症患者卵巢储备功能下降(DOR)的系列影响因素,以为不孕症防治工作的顺利开展奠定基础。方法选择该院2016年11月-2018年5月收治的62例DOR不孕症患者作为观察组;同时间段选择62名健康女性作为对照组;针对不孕症患者表现出卵巢储备功能下降的具体原因进行分析,利用Logistic多因素回归分析方法就DOR系列因素进行总结。结果观察组人工流产次数为(0.83±0.25)次,BMI为(23.36±2.82)kg/m^2,自然流产次数为(0.41±0.11)次,药物流产次数为(0.45±0.12)次,促排卵次数为(1.27±0.39)次,对照组人工流产次数为(0.51±0.13)次,BMI为(22.17±2.51)kg/m2,自然流产次数为(0.22±0.04)次,药物流产次数为(0.30±0.06)次,促排卵次数为(0.91±0.25)次,对两组研究对象实施单因素分析后发现,在人工流产次数、BMI、自然流产次数、药物流产次数以及促排卵次数差异有统计学意义(t=8.942 0,2.481 9,12.781 7,8.803 4,6.1190,P<0.05)。在子宫内膜异位症史、月经量以及盆腔手术史方面,差异有统计学意义(χ^2=14.064 8,9.217 2,12.898 8,P<0.05),伴随着人工流产次数、BMI以及促排卵次数呈现出一定程度的增加,不孕症患者表现出DOR的概率呈现出一定程度增加。针对不孕症患者表现出DOR的独立危险因素进行分析,主要集中于盆腔手术史以及子宫内膜异位症史两方面。结论对于不孕症患者表现出DOR的系列因素进行分析,主要集中于人工流产史、BMI、子宫内膜异位症史、促排卵史以及盆腔手术史几方面,对此针对DOR发生风险加以预测,于早期合理选择激素展开对应治疗,对于DOR以及不孕症的发生风险可以有效降低。 展开更多
关键词 不孕症 卵巢储备功能 影响因素
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中药补肾四连方对肾虚血瘀型不孕症的临床疗效研究 预览
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作者 丁芳 王亮 杨淑英 《河北中医药学报》 2019年第5期15-18,22共5页
目的:研究中药补肾四连方对78例肾虚血瘀型不孕症的治疗作用。方法:随机选择78例肾虚血瘀型不孕症患者,给予中药补肾四连方干预6个疗程,观察其症状、血清性激素六项及B超下子宫内膜与卵泡发育的动态变化。结果:随着用药时间的推移,⑴症... 目的:研究中药补肾四连方对78例肾虚血瘀型不孕症的治疗作用。方法:随机选择78例肾虚血瘀型不孕症患者,给予中药补肾四连方干预6个疗程,观察其症状、血清性激素六项及B超下子宫内膜与卵泡发育的动态变化。结果:随着用药时间的推移,⑴症状明显改善,如腰膝痠痛、月经稀发、痛经等;⑵血清性激素指标改善,如促黄体激素(LH)/促卵泡激素(FSH)、雌二醇(E 2)/孕酮(P)比值趋于正常,睾酮(T)降低、P升高( P <0.05);⑶超声监测到优势卵泡,且子宫内膜与优势卵泡呈协同发展;⑷受孕率提升至84.62%。结论:补肾四连方对肾虚血瘀型不孕症患者有良好的治疗作用。 展开更多
关键词 补肾四连方 周期治疗 肾虚血瘀型 不孕症 月经不调 痛经 闭经
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从阴疽论治多囊卵巢综合征 预览
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作者 赵宗耀 侯雅静 +6 位作者 闫秋莹 张曼 陈剑北 柳辰玥 陈家旭 肖飞 裴学军 《世界中医药》 CAS 2019年第9期2245-2247,共3页
笔者从病理属性,核心病机,继发病机,临床表现,现代研究五方面正反论证了多囊卵巢综合征(Polycysti Covary Syndrome,PCOS)与阴疽的一致性,提出可从阴疽论治PCOS。认为PCOS的病机是肾虚瘀聚,气血亏衰,且常郁肝虚脾兼痰,治当“补肾为主,... 笔者从病理属性,核心病机,继发病机,临床表现,现代研究五方面正反论证了多囊卵巢综合征(Polycysti Covary Syndrome,PCOS)与阴疽的一致性,提出可从阴疽论治PCOS。认为PCOS的病机是肾虚瘀聚,气血亏衰,且常郁肝虚脾兼痰,治当“补肾为主,健脾疏肝;温阳为重,活血化痰”。不应重祛瘀而略化痰,知温肾而忘疏肝,忽视了肝郁夹痰的致病作用。 展开更多
关键词 阴疽 多囊卵巢综合征 肾虚血瘀 肝郁兼痰 小金丹 气血亏虚 不孕 闭经
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子宫输卵管造影的图像解读 被引量:3
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作者 郑兴邦 关菁 《中国实用妇科与产科杂志》 CAS CSCD 北大核心 2019年第1期77-80,共4页
女性不孕症25%-35%由输卵管不孕症引起,子宫输卵管造影是诊断输卵管不孕症的一线方法。文章探讨输卵管通而不畅,输卵管近端阻塞,结节性输卵管峡部炎,输卵管远端积水,盆腔粘连,盆腔结核等常见输卵管病变的造影图像表现,以指导临床诊断和... 女性不孕症25%-35%由输卵管不孕症引起,子宫输卵管造影是诊断输卵管不孕症的一线方法。文章探讨输卵管通而不畅,输卵管近端阻塞,结节性输卵管峡部炎,输卵管远端积水,盆腔粘连,盆腔结核等常见输卵管病变的造影图像表现,以指导临床诊断和手术预后评估。 展开更多
关键词 子宫输卵管造影 不孕症 输卵管
输卵管阻塞性不孕的介入治疗
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作者 王添平 张国福 《中国实用妇科与产科杂志》 CAS CSCD 北大核心 2019年第1期83-86,共4页
输卵管因素占女性不孕症的30%-50%。子宫输卵管造影(HSG)诊断输卵管完全阻塞或部分阻塞的患者,经选择性输卵管造影(SSG)及输卵管再通术(FTR)治疗,既可以排除大部分造影中的假阳性结果,也可疏通输卵管、改善输卵管通畅度,是治疗输卵管阻... 输卵管因素占女性不孕症的30%-50%。子宫输卵管造影(HSG)诊断输卵管完全阻塞或部分阻塞的患者,经选择性输卵管造影(SSG)及输卵管再通术(FTR)治疗,既可以排除大部分造影中的假阳性结果,也可疏通输卵管、改善输卵管通畅度,是治疗输卵管阻塞性不孕的一种重要手段。 展开更多
关键词 输卵管阻塞 不孕症 介入治疗
不孕症患者发生子宫内膜息肉的影响因素 预览
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作者 蒋儒芳 杨一华 +2 位作者 冯煜 黄馨月 覃爱平 《广西医学》 CAS 2019年第1期17-19,共3页
目的探讨不孕症患者发生子宫内膜息肉的影响因素。方法回顾性分析359例不孕症患者的临床资料。根据宫腔镜检查及术后病理结果,84例诊断为子宫内膜息肉(息肉组),275例诊断为非子宫内膜息肉(非息肉组)。比较两组患者的相关临床资料,采用Lo... 目的探讨不孕症患者发生子宫内膜息肉的影响因素。方法回顾性分析359例不孕症患者的临床资料。根据宫腔镜检查及术后病理结果,84例诊断为子宫内膜息肉(息肉组),275例诊断为非子宫内膜息肉(非息肉组)。比较两组患者的相关临床资料,采用Logistic模型进行多因素分析。结果与非息肉组比较,息肉组的输卵管积水患者比例较低、子宫内膜异位症患者比例较高、月经周期稍短(均P<0.05)。多因素分析结果显示,子宫内膜异位症是不孕患者发生子宫内膜息肉的独立危险因素(P<0.05)。结论合并子宫内膜异位症的不孕症患者发生子宫内膜息肉的风险更高。 展开更多
关键词 子宫内膜息肉 不孕症 影响因素 子宫内膜异位症
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补肾活血法治疗男性少弱精子症研究进展 预览
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作者 姚增民 赵玉 +2 位作者 耿强 陈少峰 李重 《天津中医药大学学报》 CAS 2019年第3期309-312,共4页
少弱精子症是男性不育的常见病因,因其发生机制不明,现代医学缺乏针对性的治疗方式。中医学在治疗少弱精子症方面具有明显优势。补肾活血法为辨证论治少弱精子症的法则之一,越来越多的基础及临床研究证实其在改善精子质量方面效果显著... 少弱精子症是男性不育的常见病因,因其发生机制不明,现代医学缺乏针对性的治疗方式。中医学在治疗少弱精子症方面具有明显优势。补肾活血法为辨证论治少弱精子症的法则之一,越来越多的基础及临床研究证实其在改善精子质量方面效果显著。文章就近期相关研究进行综述,旨在为临床上治疗本病提供新的思路。 展开更多
关键词 补肾活血 少弱精子症 不育 进展
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大黄蛰虫胶囊联合介入疗法治疗输卵管阻塞性不孕症的临床观察 预览
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作者 王华 王生卓 《中国初级卫生保健》 2019年第8期93-94,共2页
目的观察大黄蛰虫胶囊联合介入疗法治疗输卵管阻塞性不孕症的临床疗效及作用机制。方法将60例输卵管阻塞患者随机分为观察组和对照组,每组各30例。治疗组采用大黄蛰虫胶囊联合介入疗法治疗,对照组采用介入疗法抗感染治疗。结果治疗组有... 目的观察大黄蛰虫胶囊联合介入疗法治疗输卵管阻塞性不孕症的临床疗效及作用机制。方法将60例输卵管阻塞患者随机分为观察组和对照组,每组各30例。治疗组采用大黄蛰虫胶囊联合介入疗法治疗,对照组采用介入疗法抗感染治疗。结果治疗组有效率为92.67%,对照组有效率为82.67%,两组比较差异有统计学意义(P<0.05));治疗一年后,观察组再通率、妊娠率明显高于对照组,再闭塞率低于对照组,差异有统计学意义(P<0.05);治疗后观察组患者IL-6、hs-CRP和TNF-α均低于对照组,两组治疗后均低于治疗前,差异有统计学意义(P<0.05)。结论大黄蛰虫胶囊联合介入疗法可以显著改善输卵管通畅水平,提高患者妊娠率。 展开更多
关键词 大黄蛰虫胶囊 介入疗法 输卵管阻塞 不孕症
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精索静脉曲张超声诊断及分度标准研究进展 预览
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作者 梁雁 黄君 《中国医学影像技术》 CSCD 北大核心 2019年第4期610-613,共4页
精索静脉曲张由精索内蔓状静脉丛异常扩张导致,是不育症的常见病因之一。超声检查在精索静脉曲张的诊断中具有重要价值,同时还能对精索静脉曲张进行分度,为进一步临床治疗提供依据;但目前对于超声诊断精索静脉曲张的标准及分度标准仍存... 精索静脉曲张由精索内蔓状静脉丛异常扩张导致,是不育症的常见病因之一。超声检查在精索静脉曲张的诊断中具有重要价值,同时还能对精索静脉曲张进行分度,为进一步临床治疗提供依据;但目前对于超声诊断精索静脉曲张的标准及分度标准仍存争议。本文针对相关研究进行综述,旨在探讨适用于中国人精索静脉曲张的超声诊断及分度标准。 展开更多
关键词 不育症 精索静脉曲张 超声检查 分类法
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小Y染色体对男性生育力的影响及临床效应分析 预览
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作者 张峰 刘建兵 +2 位作者 车与睿 李天赋 虞斌 《福建医科大学学报》 2019年第2期91-93,101共4页
目的探讨小Y染色体对男性生育能力的影响及临床效应分析。方法收集因不孕不育或配偶有不良孕产史就诊的男性患者1804例(实验组),分为2组,其中A组1269例,拟行体外授精/卵胞质内单精子注射-胚胎移植(IVF/ICSI-ET)技术;B组535例,配偶既往... 目的探讨小Y染色体对男性生育能力的影响及临床效应分析。方法收集因不孕不育或配偶有不良孕产史就诊的男性患者1804例(实验组),分为2组,其中A组1269例,拟行体外授精/卵胞质内单精子注射-胚胎移植(IVF/ICSI-ET)技术;B组535例,配偶既往均有不良孕产史或羊水穿刺提示胎儿染色体异常等。对照组为行羊水穿刺诊断结果为正常的男性病例656例。采用染色体G显带技术对两组患者进行核型分析,筛选小Y染色体。对检出的小Y患者应用PCR荧光探针法检测Y染色体无精子因子(AZF)的相关序列标签位点。结果实验组共检出小Y染色体44例,其中A组31例,B组13例(已剔除1例);对照组检出6例。A组及B组的小Y染色体检出率与对照组比较,差别均有统计学意义(P<0.05),而A组与B组间差别无统计学意义(P>0.05)。Y染色体微缺失检测发现,A组AZF微缺失3例,其中2例为AZFc缺失,1例为AZFb+c复合缺失,B组未发现AZF微缺失,AZF微缺失发生率为6.81%(3/44)。结论小Y染色体可能与男性不育及不良妊娠结局的发生有关,存在潜在的临床效应。 展开更多
关键词 Y染色体 不育 男(雄)性 核型分析 染色体 Y/遗传学
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