<strong>Introduction: </strong>Pain with neuropathic characteristics is one of the most limiting as a consequence of injury or disease that affects the somatosensory system. <strong>Objective: </s...<strong>Introduction: </strong>Pain with neuropathic characteristics is one of the most limiting as a consequence of injury or disease that affects the somatosensory system. <strong>Objective: </strong>An assessment protocol is proposed to quantify the impact of neuropathic pain integrating personal, clinical, work and social aspects and to establish guidelines in its management and evolutionary control. <strong>Method:</strong> The medical literature on neuropathic pain and its impact is reviewed as a basis for including the variables that must be part of the protocol. <strong>Results:</strong> The variables are quantified individually and by groups of factors. The final result is stratified into four grades (mild, moderate, severe, extreme), which will serve for the subsequent control, monitoring and prevention of risks. <strong>Conclusion:</strong> The proposed protocol evaluates the impact of neuropathic pain in all aspects of the person who suffers it and quantifies the results establishing degrees for its control, follow-up and clinical, social and occupational intervention.展开更多
Whether resection of recurrent colorectal cancer liver metastases (CLMs) can be safely performed after prior hepatectomy, especially after two-stage hepatectomy (TSH), and to what extent this aggressive surgical appro...Whether resection of recurrent colorectal cancer liver metastases (CLMs) can be safely performed after prior hepatectomy, especially after two-stage hepatectomy (TSH), and to what extent this aggressive surgical approach may impact patient outcomes and prolong survival, are important issues to investigate. To this end, Imai and colleagues recently published the Hospital Paul Brousse experience with resection of recurrent CLMs after TSH (1). In this study, the authors analyzed 93 patients who underwent TSH, among whom 81 had "globally curative"surgery, when all known disease—including extrahepatic disease if present—was successfully resected. Of these 81 patients, 62 (76.5%) experienced recurrence. For their entire study cohort, repeat liver surgery was ultimately performed in more than half of the patients, and survival for these patients was significantly greater than that for patients who did not undergo resection (45.8% vs. 26.3%, P=0.004). In fact, repeat hepatectomy for recurrence was the strongest independent predictor for improved survival. As the authors conclude, these results underscore the value of oncologic surveillance and the critical role of repeat hepatectomy. The present work expands on the concept of "third hepatectomy" previously reported by the same authors, focusing on those patients who have undergone the most aggressive surgical treatment of their prior CLMs in the form of TSH involving portal vein embolization and major hepatectomy (2).展开更多
Benign prostatic hyperplasia,which can be abbreviated as prostatic hyperplasia,is a urinary system disease that has a high incidence in middle-aged and elderly male populations in China.The incidence of benign prostat...Benign prostatic hyperplasia,which can be abbreviated as prostatic hyperplasia,is a urinary system disease that has a high incidence in middle-aged and elderly male populations in China.The incidence of benign prostatic hyperplasia is increasing year by year.Patients with benign prostatic hyperplasia are prone to have bladder outlet obstruction,which in turn leads to an increase in residual urine volume in the bladder and impurities in the urine,such as upper urinary calculi that enter the bladder,urine crystals,various exfoliated cells,etc.If these substances stay in the bladder for a long time,stones in the bladder will be generated.Benign prostatic hyperplasia with bladder stones can severely obstruct the urinary tract,causing clinical symptoms such as urinary tract infections,urinary urgency,frequent urination,and dysuria.These symptoms seriously affects the physical and mental health of patients,leading to low levels of normal work and quality of life.With the development of medical technology,surgical treatment is commonly used in clinical practice.Among them,transurethral prostatectomy is widely used in clinical treatment,and has achieved good results.展开更多
文摘<strong>Introduction: </strong>Pain with neuropathic characteristics is one of the most limiting as a consequence of injury or disease that affects the somatosensory system. <strong>Objective: </strong>An assessment protocol is proposed to quantify the impact of neuropathic pain integrating personal, clinical, work and social aspects and to establish guidelines in its management and evolutionary control. <strong>Method:</strong> The medical literature on neuropathic pain and its impact is reviewed as a basis for including the variables that must be part of the protocol. <strong>Results:</strong> The variables are quantified individually and by groups of factors. The final result is stratified into four grades (mild, moderate, severe, extreme), which will serve for the subsequent control, monitoring and prevention of risks. <strong>Conclusion:</strong> The proposed protocol evaluates the impact of neuropathic pain in all aspects of the person who suffers it and quantifies the results establishing degrees for its control, follow-up and clinical, social and occupational intervention.
基金The MD Anderson Cancer Center support grant P30 CA016672.
文摘Whether resection of recurrent colorectal cancer liver metastases (CLMs) can be safely performed after prior hepatectomy, especially after two-stage hepatectomy (TSH), and to what extent this aggressive surgical approach may impact patient outcomes and prolong survival, are important issues to investigate. To this end, Imai and colleagues recently published the Hospital Paul Brousse experience with resection of recurrent CLMs after TSH (1). In this study, the authors analyzed 93 patients who underwent TSH, among whom 81 had "globally curative"surgery, when all known disease—including extrahepatic disease if present—was successfully resected. Of these 81 patients, 62 (76.5%) experienced recurrence. For their entire study cohort, repeat liver surgery was ultimately performed in more than half of the patients, and survival for these patients was significantly greater than that for patients who did not undergo resection (45.8% vs. 26.3%, P=0.004). In fact, repeat hepatectomy for recurrence was the strongest independent predictor for improved survival. As the authors conclude, these results underscore the value of oncologic surveillance and the critical role of repeat hepatectomy. The present work expands on the concept of "third hepatectomy" previously reported by the same authors, focusing on those patients who have undergone the most aggressive surgical treatment of their prior CLMs in the form of TSH involving portal vein embolization and major hepatectomy (2).
文摘Benign prostatic hyperplasia,which can be abbreviated as prostatic hyperplasia,is a urinary system disease that has a high incidence in middle-aged and elderly male populations in China.The incidence of benign prostatic hyperplasia is increasing year by year.Patients with benign prostatic hyperplasia are prone to have bladder outlet obstruction,which in turn leads to an increase in residual urine volume in the bladder and impurities in the urine,such as upper urinary calculi that enter the bladder,urine crystals,various exfoliated cells,etc.If these substances stay in the bladder for a long time,stones in the bladder will be generated.Benign prostatic hyperplasia with bladder stones can severely obstruct the urinary tract,causing clinical symptoms such as urinary tract infections,urinary urgency,frequent urination,and dysuria.These symptoms seriously affects the physical and mental health of patients,leading to low levels of normal work and quality of life.With the development of medical technology,surgical treatment is commonly used in clinical practice.Among them,transurethral prostatectomy is widely used in clinical treatment,and has achieved good results.