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Significance of multivisceral resections in oncologic surgery: A systematic review of the literature 预览
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作者 Giorgi Nadiradze Can Yurttas +1 位作者 Alfred Konigsrainer Philipp Horvath 《世界荟萃分析杂志》 2019年第6期269-289,共21页
BACKGROUND Multivisceral resections (MVR) are often necessary to reach clear resections margins but are associated with relevant morbidity and mortality. Factors associated with favorable oncologic outcomes and elevat... BACKGROUND Multivisceral resections (MVR) are often necessary to reach clear resections margins but are associated with relevant morbidity and mortality. Factors associated with favorable oncologic outcomes and elevated morbidity rates are not clearly defined. AIM To systematically review the literature on oncologic long-term outcomes and morbidity and mortality in cancer surgery a systematic review of the literature was performed. METHODS PubMed was searched for relevant articles (published from 2000 to 2018). Retrieved abstracts were independently screened for relevance and data were extracted from selected studies by two researchers. RESULTS Included were 37 studies with 3112 patients receiving MVR for colorectal cancer (1095 for colon cancer, 1357 for rectal cancer, and in 660 patients origin was not specified). The most common resected organs were the small intestine, bladder and reproductive organs. Median postoperative morbidity rate was 37.9%(range: 7% to 76.6%) and median postoperative mortality rate was 1.3%(range: 0% to 10%). The median conversion rate for laparoscopic MVR was 7.9%(range: 4.5% to 33%). The median blood loss was lower after laparoscopic MVR compared to the open approach (60 mL vs 638 mL). Lymph-node harvest after laparoscopic MVR was comparable. Report on survival rates was heterogeneous, but the 5-year overall-survival rate ranged from 36.7% to 90%, being worst in recurrent rectalcancer patients with a median 5-year overall survival of 23%. R0 -resection, primary disease setting and no lymph-node or lymphovascular involvement were the strongest predictors for long-term survival. The presence of true malignant adhesions was not exclusively associated with poorer prognosis. Included were 16 studies with 1.600 patients receiving MVR for gastric cancer. The rate of morbidity ranged from 11.8% to 59.8%, and the main postoperative complications were pancreatic fistulas and pancreatitis, anastomotic leakage, cardiopulmonary events and post-operative bleedings. Total mortality was between 0% a 展开更多
关键词 COLORECTAL CANCER Gastric CANCER Primary RECURRENT Multivisceral RESECTION Hyperthermic INTRAPERITONEAL chemotherapy MORBIDITY
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较小的胆道结石和延期胆囊切除术可增加胆源性胰腺炎复发 预览
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作者 赵浩东 张刘兆 +3 位作者 吴雪生 陈卫东 刘辉 王兴宇 《肝胆外科杂志》 2019年第3期198-200,共3页
目的探讨急性胆源性胰腺炎(ABP)发生及复发的危险因素,并比较两种胆囊切除手术时机对ABP患者复发率的影响。方法选取安徽医科大学第一附属医院急诊外科2017年收治的ABP患者进行分析。将患者分为两组,复发性ABP患者(A组)及非复发性的ABP... 目的探讨急性胆源性胰腺炎(ABP)发生及复发的危险因素,并比较两种胆囊切除手术时机对ABP患者复发率的影响。方法选取安徽医科大学第一附属医院急诊外科2017年收治的ABP患者进行分析。将患者分为两组,复发性ABP患者(A组)及非复发性的ABP患者(B组)。结果延期胆囊切除术组与早期胆囊切除术组相比,ABP复发的风险明显增加(52.0%vs.7.4%,P<0.001)。在多因素回归分析显示,直径小于等于0.5cm的胆囊结石和胆囊切除术延迟是导致ABP复发的危险因素。结论小于等于0.5cm的胆囊结石和延期胆囊切除术是导致ABP复发的危险因素。 展开更多
关键词 急性胆源性胰腺炎 胆结石 胆囊切除术
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克霉唑联合左旋咪唑治疗外阴阴道假丝酵母菌病的效果 预览
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作者 蔡丽华 蔡文莲 《中国当代医药》 2019年第10期144-146,共3页
目的探讨克霉唑联合左旋咪唑治疗外阴阴道假丝酵母菌病的效果。方法选择鄂州市妇幼保健院妇女保健科2014年7月~2015年12月就诊的160例外阴阴道假丝酵母菌患者的临床资料,根据治疗方法不同,分为观察组和对照组,各80例。对照组给予克霉唑... 目的探讨克霉唑联合左旋咪唑治疗外阴阴道假丝酵母菌病的效果。方法选择鄂州市妇幼保健院妇女保健科2014年7月~2015年12月就诊的160例外阴阴道假丝酵母菌患者的临床资料,根据治疗方法不同,分为观察组和对照组,各80例。对照组给予克霉唑阴道用药,观察组在对照组基础上加用口服左旋咪唑,比较两组的临床疗效和复发率。结果观察组的临床治愈率为97.5%,明显高于对照组的82.5%,差异有统计学意义(P<0.01)。观察组的复发率为5.13%,明显低于对照组的15.15%,差异有统计学意义(P<0.01)。结论克霉唑联合左旋咪唑治疗外阴阴道假丝酵母菌病可以提高疗效,降低复发率,值得临床推广应用。 展开更多
关键词 左旋咪唑 复发性 外阴阴道假丝酵母菌 免疫调节
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孟鲁司特钠治疗小儿哮喘临床效果分析 预览
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作者 卢文强 《中国继续医学教育》 2019年第28期125-127,共3页
目的分析孟鲁司特钠治疗小儿哮喘临床效果、复发及不良反应。方法选择本院2015年5月—2018年5月收治的小儿哮喘患者作为研究对象,一共80例,随机分组,各组为40例,对照组给予常规治疗,观察组在常规治疗的前提下,结合白三烯受体拮抗剂孟鲁... 目的分析孟鲁司特钠治疗小儿哮喘临床效果、复发及不良反应。方法选择本院2015年5月—2018年5月收治的小儿哮喘患者作为研究对象,一共80例,随机分组,各组为40例,对照组给予常规治疗,观察组在常规治疗的前提下,结合白三烯受体拮抗剂孟鲁司特钠,治疗两周后比较两组患者的治疗疗效、复发情况、不良反应。结果(1)观察组治疗有效率明显高于对照组,P<0.05。(2)观察组复发率为2.50%,对照组复发率为25.00%,观察组复发率明显低于对照组,P<0.05。同时,观察组症状缓解时间和肺部症状结束时间明显比对照组更短,P<0.05。(3)观察组不良反应率明显低于对照组,P<0.05。结论孟鲁司特钠治疗小儿哮喘的疗效确切。 展开更多
关键词 孟鲁司特钠 治疗 小儿哮喘 效果 复发 不良反应
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Microsurgical ligation for incompletely coiled or recurrent intracranial aneurysms:a 17-year single-center experience
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作者 Jun Wu Xianzeng Tong +3 位作者 Qingyuan Liu Yong Cao Yuanli Zhao Shuo Wang 《中华神经外科杂志(英文)》 CSCD 2019年第2期71-84,共14页
Background:In this retrospective single-center study,we presented our experience in the microsurgical management of incompletely coiled or recurrent aneurysms after initial endovascular coiling.Methods:During a 17-yea... Background:In this retrospective single-center study,we presented our experience in the microsurgical management of incompletely coiled or recurrent aneurysms after initial endovascular coiling.Methods:During a 17-year period,48 patients underwent microsurgical clipping of incompletely coiled or recurrent aneurysms after coiling (Gurian group B).The clinical data,surgical technique,and postoperative outcome were recorded and analyzed.Results:Before coiling,42 patients (87.5%) experienced aneurysm rupture.Most of the aneurysms (46/48,96%) were located in the anterior circulation.After coiling,6 patients had incompletely coiled aneurysms and 42 patients had recurrent aneurysms,with a mean time of 20.2 months from coiling to recurrence.Coil extrusion occurred in none of the incompletely coiled aneurysms and 71% (30/42) of the recurrent aneurysms.Clipping techniques are direct microsurgical clipping without coil removal in 16 patients,partial coil removal in 14 patients,and total coil removal in 18 patients.Postoperative and follow-up angiography revealed complete occlusion of the aneurysms in all patients.No patient died during postoperative follow-up period (mean,78.9 months;range,10-190 months).Good outcomes (GOS of 4 or 5) were achieved in 87.5% (42/48) of the patients at the final follow-up.Conclusions:Microsurgical clipping is effective for incompletely coiled or recurrent aneurysms after initial coiling.For recurrent aneurysms that have coils in the neck,have no adequate neck for clipping,or cause mass effects on surrounding structures,partial or total removal of coiled mass can facilitate surgical clipping and lead to successful obliteration of the aneurysms. 展开更多
关键词 Coiled ANEURYSMS RECURRENT ANEURYSMS ENDOVASCULAR COILING Microsurgical CLIPPING
Expanding etiology of progressive familial intrahepatic cholestasis 预览
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作者 Sarah AF Henkel Judy H Squires +3 位作者 Mary Ayers Armando Ganoza Patrick Mckiernan James E Squires 《世界肝病学杂志:英文版(电子版)》 2019年第5期450-463,共14页
BACKGROUND Progressive familial intrahepatic cholestasis(PFIC)refers to a disparate group of autosomal recessive disorders that are linked by the inability to appropriately form and excrete bile from hepatocytes,resul... BACKGROUND Progressive familial intrahepatic cholestasis(PFIC)refers to a disparate group of autosomal recessive disorders that are linked by the inability to appropriately form and excrete bile from hepatocytes,resulting in a hepatocellular form of cholestasis.While the diagnosis of such disorders had historically been based on pattern recognition of unremitting cholestasis without other identified molecular or anatomic cause,recent scientific advancements have uncovered multiple specific responsible proteins.The variety of identified defects has resulted in an ever-broadening phenotypic spectrum,ranging from traditional benign recurrent jaundice to progressive cholestasis and end-stage liver disease.AIM To review current data on defects in bile acid homeostasis,explore the expanding knowledge base of genetic based diseases in this field,and report disease characteristics and management.METHODS We conducted a systemic review according to PRISMA guidelines.We performed a Medline/PubMed search in February-March 2019 for relevant articles relating to the understanding,diagnosis,and management of bile acid homeostasis with a focus on the family of diseases collectively known as PFIC.English only articles were accessed in full.The manual search included references of retrieved articles.We extracted data on disease characteristics,associations with other diseases,and treatment.Data was summarized and presented in text,figure,and table format.RESULTS Genetic-based liver disease resulting in the inability to properly form and secrete bile constitute an important cause of morbidity and mortality in children and increasingly in adults.A growing number of PFIC have been described based on an expanded understanding of biliary transport mechanism defects and the development of a common phenotype.CONCLUSION We present a summary of current advances made in a number of areas relevant to both the classically described FIC1(ATP8B1),BSEP(ABCB11),and MDR3(ABCB4)transporter deficiencies,as well as more recently described gene mutati 展开更多
关键词 CHOLESTASIS Progressive FAMILIAL INTRAHEPATIC CHOLESTASIS BENIGN recurrent INTRAHEPATIC CHOLESTASIS INTRAHEPATIC CHOLESTASIS of pregnancy Drug induced CHOLESTASIS BILE acids BILE transport
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Asymmetric Dimethylarginine Predicts One-year Recurrent Cardiovascular Events: Potential Biomarker of 'Toxin Syndrome' in Coronary Heart Disease
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作者 XU Hao CHEN Zhuo +4 位作者 SHANG Qing-hua GAO Zhu-ye YU Chang-an SHI Da-zhuo CHEN Ke-ji 《中国结合医学杂志:英文版》 SCIE CAS CSCD 2019年第5期327-333,共7页
Objective: To examine the prognostic value of serum levels of asymmetric dimethylarginine(ADMA)in patients with stable coronary heart disease(CHD) thus explore a potential biomarker of 'toxin syndrome' in CHD.... Objective: To examine the prognostic value of serum levels of asymmetric dimethylarginine(ADMA)in patients with stable coronary heart disease(CHD) thus explore a potential biomarker of 'toxin syndrome' in CHD.Methods: In this prospective nested case-control study, 36 of 1,503 Chinese patients with stable CHD experienced at least 1 recurrent cardiovascular event(RCE) during 1-year fol ow-up. Serum levels of ADMA at the start of fol ow-up were compared between these 36 cases and 36 controls which matched to cases in terms of gender, age, history of hypertension, and myocardial infarction. Results: Based on the crude model, subjects in the 2 highest ADMA quartiles showed signi?cantly higher risk of developing RCE than those in the lowest ADMA quartile (odds ratio(OR) 4.09, 95%confidence interval(CI) 1.01 to 16.58;OR 6.76, 95% CI 1.57 to 29.07)This association was also observed in the case-mix model(OR 5.51, 95% CI 1.23 to 24.61;OR 7.83, 95% CI 1.68 to 36.41) and multivariable model(OR 6.64,95% CI 1.40 to 31.49;OR 13.14, 95% CI 2.28 to 75.71) after adjusting for confounders. The multivariable model which combined ADMA and high-sensitivity C-reactive protein(hs CRP) showed better predictive power with areas under the receiver operator characteristic curves(0.779) than the model of either ADMA(0.694) or hs CRP(0.636). Conclusion:Serum ADMA level may be a potential biomarker of 'toxin syndrome' in CHD which shows favorable prognostic value in predicting 1-year RCE in patients with stable CHD. [The registration number is Chi CTR-PRNRC-07000012] 展开更多
关键词 asymmetric DIMETHYLARGININE RECURRENT cardiovascular event nested CASE-CONTROL study coronary heart disease TOXIN SYNDROME
口腔溃疡含片治疗复发性阿弗他溃疡的临床效果观察
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作者 张传钦 《智慧健康》 2019年第24期73-74,共2页
目的观察并分析口腔溃疡含片治疗复发性阿弗他溃疡的临床效果。方法遵循随机性的原则从医院收治的复发性阿弗他溃疡患者中抽取86例作为临床观察的对象,按照患者的不同入院顺序,将全部患者等量划分为对照组和研究组两组,平均每组中各有4... 目的观察并分析口腔溃疡含片治疗复发性阿弗他溃疡的临床效果。方法遵循随机性的原则从医院收治的复发性阿弗他溃疡患者中抽取86例作为临床观察的对象,按照患者的不同入院顺序,将全部患者等量划分为对照组和研究组两组,平均每组中各有43例患者。对对照组的患者主要使用口腔溃疡散治疗,对研究组的患者则主要应用口腔溃疡含片治疗。对比性研究两组患者在不同治疗方法下的临床效果以及不良反应症状的发生率。结果研究组患者口腔溃疡愈合时间(6.5±1.3)min短于对照组的(11.2±1.8)min,研究组疼痛度评分(1.1±0.4)分、不良症状发生率6.98%、溃疡复发率2.33%均低于对照组的疼痛度评分(2.8±1.6)分、不良症状发生率16.28%、溃疡复发率11.63%;且研究组的临床治疗总有效率为86.05%,显著高于对照组的67.41%。则口腔溃疡含片治疗复发性阿弗他溃疡的临床效果较好,具备统计学意义(P <0.05)。结论口腔溃疡含片治疗复发性阿弗他溃疡的临床效果较为显著,有效缓解了患者口腔溃疡的疼痛度,临床应用价值较为突出,值得在临床实践中作进一步的推广和使用。 展开更多
关键词 口腔溃疡散 口腔溃疡含片 复发性 阿弗他溃疡 临床效果
Risk factors for recurrent thrombosis in patients with polycythemia vera and essential thrombocythemia
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作者 韩雪 《中国医学文摘:内科学分册(英文版)》 2019年第2期120-121,共2页
Objective To analyze the clinical characteristics ofrecurrent thrombosis in patients with polycythemia vera(PV) and essential thrombocythemia (ET) to probe therisk factors for recurrent thrombosis in patients with ETa... Objective To analyze the clinical characteristics ofrecurrent thrombosis in patients with polycythemia vera(PV) and essential thrombocythemia (ET) to probe therisk factors for recurrent thrombosis in patients with ETand PV. Methods The clinical data of 104 ET and PVpatients with thrombosis in Beijing Anzhen Hospital fromFebruary 2001 to November 2016 were retrospectivelyanalyzed. Thrombosis reoccurred in 38 patients. Statisticalanalyses were performed by multivariate logistic regressionfor risk factors of recurrent thrombosis in ET andPV patients. Results Recurrent thrombosis occurred in36. 5% of patients with ET /PV,the total incidence ratein ET and PV patients was 9. 8% patient-years,12. 3%patient-years and 5. 7% patient-years in ET and PV respectively.There were 56 re-thrombotic events,and42. 1% of events occurred within 1 year after the firstthrombosis. 展开更多
关键词 Risk factors RECURRENT THROMBOSIS in PATIENTS POLYCYTHEMIA VERA essential THROMBOCYTHEMIA ACS
上睑联合筋膜鞘(CFS)治疗复发性中重度上睑下垂 预览 被引量:1
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作者 陈贵宗 田跃平 +2 位作者 罗延平 刘涛 李勤 《中国美容医学》 CAS 2019年第1期6-8,共3页
目的:探讨一种矫正中重度上睑下垂术后复发的稳定可靠的手术方法。方法:2016年1月-2017年12月,共治疗复发性重度上睑下垂16例,其中双眼10例,单眼6例,共26只眼,局麻下首先剥离出睑板组织,仔细分离前次手术瘢痕粘连组织,解剖出变性额肌组... 目的:探讨一种矫正中重度上睑下垂术后复发的稳定可靠的手术方法。方法:2016年1月-2017年12月,共治疗复发性重度上睑下垂16例,其中双眼10例,单眼6例,共26只眼,局麻下首先剥离出睑板组织,仔细分离前次手术瘢痕粘连组织,解剖出变性额肌组织或提上睑肌,于结膜与上睑提肌腱膜下向后上分离至上睑结膜穹窿处,见白色增厚联合腱膜鞘,6-0尼龙线将睑板悬挂缝合于联合腱膜上,再将提肌腱膜向前下方牵拉缝合于睑板上。术中调整缝挂联合腱膜及上睑提肌的位置,将上睑缘调整至合适的高度及睑缘曲率流畅。结果:随访6个月~1年,满意25只眼,1只欠满意,无明显严重并发症,轻度闭合不全在3个月内基本恢复,无角膜暴露。结论:上睑联合腱膜鞘(CFS)及上睑提肌腱膜前徒手术可以稳定有效矫正复发性中重度上睑下垂,术后闭合不全发生率低,美容效果好,复发率低。 展开更多
关键词 上睑下垂 复发性 中重度 上睑联合腱膜鞘(CFS)
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复发性与首发性脑梗死患者头颈部CT的血管成像特点分析 预览
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作者 王国昕 刘家树 《中国继续医学教育》 2019年第5期73-75,共3页
目的分析复发性与首发性脑梗死患者头颈部CT的血管成像特点。方法回顾性分析2015年6月—2018年6月我院38例复发性脑梗死(复发组)与40例首发性脑梗死(首发组)患者的影像资料。观察两组是否存在头颈部动脉狭窄,以及头颈部动脉斑块的类型... 目的分析复发性与首发性脑梗死患者头颈部CT的血管成像特点。方法回顾性分析2015年6月—2018年6月我院38例复发性脑梗死(复发组)与40例首发性脑梗死(首发组)患者的影像资料。观察两组是否存在头颈部动脉狭窄,以及头颈部动脉斑块的类型。结果复发组头颈部动脉狭窄率为89.47%,高于首发组的60.00%(P<0.05)。复发组软斑与溃疡斑发生率为35.80%、53.09%,高于首发组的17.50%、27.50%(P<0.05)。首发组硬斑的发生率为55.00%,高于复发组的11.11%(P<0.05)。结论复发性与首发性脑梗死的头颈部CT的血管成像存在明显差异,主要表现为头颈部动脉狭窄情况与动脉斑块类型,临床应做好相应的预防措施。 展开更多
关键词 复发性 首发性 脑梗死 头颈部CT 血管成像 成像特点
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Code Attention: translating source code to comments by exploiting the code constructs
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作者 Wenhao ZHENG Hongyu ZHOU +1 位作者 Ming LI Jianxin WU 《中国计算机科学前沿:英文版》 SCIE EI CSCD 2019年第3期565-578,共14页
Appropriate comments of code snippets provide insight for code functionality, which are helpful for program comprehension. However, due to the great cost of authoring with the comments, many code projects do not conta... Appropriate comments of code snippets provide insight for code functionality, which are helpful for program comprehension. However, due to the great cost of authoring with the comments, many code projects do not contain adequate comments. Automatic comment generation techniques have been proposed to generate comments from pieces of code in order to alleviate the human efforts in annotating the code. Most existing approaches attempt to exploit certain correlations (usually manually given) between code and generated comments, which could be easily violated if coding patterns change and hence the performance of comment generation declines. In addition, recent approaches ignore exploiting the code constructs and leveraging the code snippets like plain text. Furthermore, previous datasets are also too small to validate the methods and show their advantage. In this paper, we propose a new attention mechanism called CodeAttention to translate code to comments, which is able to utilize the code constructs, such as critical statements, symbols and keywords. By focusing on these specific points, CodeAttention could understand the semantic meanings of code better than previous methods. To verify our approach in wider coding patterns, we build a large dataset from open projects in GitHub. Experimental results in this large dataset demonstrate that the proposed method has better performance over existing approaches in both objective and subjective evaluation. We also perform ablation studies to determine effects of different parts in CodeAttention. 展开更多
关键词 software mining machine learning CODE COMMENT generation recurrent neural network ATTENTION mechanism
Treatment of Uncomplicated Recurrent Urinary Tract Infection with Chinese Medicine Formula: A Randomized Controlled Trial
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作者 LIU Shi-wei GUO Jie +2 位作者 WU Wei-kang CHEN Ze-liang ZHANG Ning 《中国结合医学杂志:英文版》 SCIE CAS CSCD 2019年第1期16-22,共7页
Objective:To evaluate Chinese medicine (CM)formula Bazheng Powder (八正散)as an alternative therapeutic option for female patients with recurrent urinary tract infection (RUTI).Methods:A randomized double-blinded tria... Objective:To evaluate Chinese medicine (CM)formula Bazheng Powder (八正散)as an alternative therapeutic option for female patients with recurrent urinary tract infection (RUTI).Methods:A randomized double-blinded trial was performed.Eligible female patients with RUTI were recruited from one hospital and two community health centers.By using a blocked randomization scheme,participants were randomized to receive a CM formula (10 herbs)and antibiotics placebo for 4 weeks,or antibiotics for 1 week followed by 3 weeks of placebo and CM formula placebo.Clinical cure rate and microbiological cure and recurrence after treatment were evaluated.Results:A total 122 eligible patients were enrolled,with 61 cases in each group.The clinical cure rate by the intent-to-treatment approach was 90.2% or the CM group and 82.0% for the antibiotics group (P>0.05).Bacteria were cleared from 88.5%(54/61)of patients in the CM group and 82.0%(50/61)in the antibiotics group.The recurrence rate in recovered patients at the 6-month follow-up was 9.1%(5/61)and 14.0(7/61)in the CM and antibiotics groups,respectively (P>0.05).Conclusion:CM formula Bazheng Powder is a good alternative option for RUTI treatment.(Registration No.NCT01745328) 展开更多
关键词 Chinese medicine RECURRENT URINARY TRACT infection RANDOMIZED control TRIAL
Is CT scan a predictor of instability in recurrent dislocation shoulder?
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作者 K.P.Shijith Munish Sood +1 位作者 Ajay Deep Sud Amresh Ghai 《中华创伤杂志:英文版》 CAS CSCD 2019年第3期177-181,共5页
Purpose: Glenoid bone defect and the defect on the posterior-superior surface of the humerus “Hill- Sachs lesion” are the commonly seen bony lesions in patients with recurrent dislocation shoulder. Computed tomograp... Purpose: Glenoid bone defect and the defect on the posterior-superior surface of the humerus “Hill- Sachs lesion” are the commonly seen bony lesions in patients with recurrent dislocation shoulder. Computed tomography (CT) scan is considered as the best option in assessing the bony defects in the recurrent dislocation shoulder. The aim of this study was to assess the clinical and radiological corelation in the patients with recurrent dislocation shoulder. Methods: Forty-four patients of recurrent dislocation shoulder who were evaluated between January 2015 and December 2017 at a tertiary care center, clinically and radiologically using CT scan and meeting the inclusion criteria, were included. The correlation between the clinical history of the number of dislocations and the bone loss using CT scan was evaluated. Two sided statistical tests were performed at a significance level of α=0.05. The analysis was conducted using IBM SPSS STATISTICS (version 22.0). Results: All the patients were male with mean age of 25.95 (SD ± 4.2) years were evaluated. Twenty-four patients sustained injury in sporting activities while 20 patients sustained injury in training. There were an average of 4.68 (SD ± 3.1, range 2e15, median 3) episodes of dislocation. Forty-one patients had the glenoid bone loss while 40 had the Hill-Sachs lesions. The mean glenoid width defect was 10.80%(range 0e27%) while the mean Hill-Sachs defect was 14.27 mm (range 0e26.6 mm). The mean area of bone loss of the glenoid surface was 10.81%(range 0e22.4%). The lesions were on track in 34 patients and off track in 10 patients. Conclusions: CT scan of the shoulder joint is an effective method for assessing the amount of bone loss. The number of dislocations are correlated significantly with off-track lesions and the amount of bone loss on the glenoid and Hill-Sachs lesion. The glenoid width bone loss of more than 9.80% or Hill-Sachs defect of more than 14.80 mm are the critical defects after which the frequency of dislocations increases. 展开更多
关键词 SHOULDER joint RECURRENT DISLOCATION HILL-SACHS LESION
复发高级别矢状窦旁脑膜瘤的显微外科手术治疗 预览
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作者 田海龙 刘斌 +4 位作者 危兆胜 钟原 郭文强 王超超 王志刚 《中国微侵袭神经外科杂志》 CAS 2019年第4期165-167,共3页
目的探讨显微外科治疗复发高级别矢状窦旁脑膜瘤的临床疗效,并进一步总结此类肿瘤的治疗经验。方法回顾性分析8例显微外科手术切除的复发高级别矢状窦旁脑膜瘤(WHOⅡ和Ⅲ级)病人的临床资料。6例肿瘤侵犯矢状窦腔和矢状窦壁的病人中,5例... 目的探讨显微外科治疗复发高级别矢状窦旁脑膜瘤的临床疗效,并进一步总结此类肿瘤的治疗经验。方法回顾性分析8例显微外科手术切除的复发高级别矢状窦旁脑膜瘤(WHOⅡ和Ⅲ级)病人的临床资料。6例肿瘤侵犯矢状窦腔和矢状窦壁的病人中,5例矢状窦未完全闭塞;余2例仅侵犯矢状窦壁和大脑镰。结果肿瘤切除程度:侵犯矢状窦腔和矢状窦壁的6例,其中SimpsonⅡ级切除4例,Ⅲ级切除2例;侵犯矢状窦壁和大脑镰的2例,其中SimpsonⅠ级切除1例,Ⅱ级切除1例。术后病理:不典型脑膜瘤4例(WHOⅡ级),脊索样脑膜瘤1例(WHOⅡ级),横纹肌样脑膜瘤1例(WHOⅢ级),间变型脑膜瘤2例(WHOⅢ级)。1例间变型脑膜瘤术后2个月死于脑脊液感染,余7例行常规放射治疗。随访7例,时间4~48个月,复发1例,偏瘫2例,余4例恢复良好。结论显微手术切除复发高级别矢状窦旁脑膜瘤可取得良好疗效,术前需做好周密的手术计划,术中应用神经电生理监测技术保护好与复发肿瘤明显黏连的引流静脉和脑组织,处理好肿瘤与上矢状窦的关系。 展开更多
关键词 脑膜瘤 矢状窦旁 高级别 复发 显微外科手术 放射治疗
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Pediatric recurrent Clostridium difficile infections in immunocompetent children:Lessons learned from case reports of the first twelve consecutive patients 预览
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作者 Angela Chu Sonia Michail 《世界荟萃分析杂志》 2019年第7期350-357,共8页
BACKGROUND Recurrent Clostridium difficile infection(CDI)in children can be difficult to manage and may represent an unidentified underlying pathology.Recurrence can be frequently encountered in immunodeficiency disor... BACKGROUND Recurrent Clostridium difficile infection(CDI)in children can be difficult to manage and may represent an unidentified underlying pathology.Recurrence can be frequently encountered in immunodeficiency disorders and inflammatory bowel disease(IBD).AIM To report cases of a select population of children with recurrent CDI who are immunocompetent and do not have an identified IBD and examine the potential for any underlying risk factors,disease course and disease outcome.METHODS Review of charts for children aged 1-21 years with recurrent CDI referred to see pediatric gastroenterology service was performed.All subjects with known immunosuppression or IBD were excluded.Subjects were followed for at least 24 mo.RESULTS Twelve children seen consecutively were identified.All patients were treated with antibiotic courses for CDI prior to their referral.Five out of 12 patients had an underlying pathology that was not previously identified,including eosinophilic colitis and IBD.CDI symptoms resolved after treatment of underlying colitis without the need to target therapy for CDI.There were 9 patients that failed antibiotic treatment of CDI and required fecal microbiome transplant,which was safe and highly effective in preventing recurrence(100%efficacy).The gut microbial changes after fecal transplant were characterized by a remarkable and durable increase in diversity and in abundance of Bacteroides.CONCLUSION Pediatric patients with frequent recurrence of CDI may have an unidentified underlying gastrointestinal pathology that may warrant further investigation by a specialist who can identify these diseases and help optimize management.Many of these children may benefit from fecal microbial transplant which appears to be a safe,highly effective therapy that results in long term changes in the gut microbiome. 展开更多
关键词 RECURRENT Clostridium DIFFICILE infection EOSINOPHILIC colitis Inflammatory bowel disease FECAL MICROBIOME transplant
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Learning Hand Latent Features for Unsupervised 3D Hand Pose Estimation 预览
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作者 Jamal Banzi Isack Bulugu Zhongfu Ye 《自主智能(英文)》 2019年第1期1-10,共10页
Recent hand pose estimation methods require large numbers of annotated training data to extract the dynamic information from a hand representation.Nevertheless,precise and dense annotation on the real data is difficul... Recent hand pose estimation methods require large numbers of annotated training data to extract the dynamic information from a hand representation.Nevertheless,precise and dense annotation on the real data is difficult to come by and the amount of information passed to the training algorithm is significantly higher.This paper presents an approach to developing a hand pose estimation system which can accurately regress a 3D pose in an unsupervised manner.The whole process is performed in three stages.Firstly,the hand is modelled by a novel latent tree dependency model (LTDM) which transforms internal joints location to an explicit representation.Secondly,we perform predictive coding of image sequences of hand poses in order to capture latent features underlying a given image without supervision.A mapping is then performed between an image depth and a generated representation.Thirdly,the hand joints are regressed using convolutional neural networks to finally estimate the latent pose given some depth map.Finally,an unsupervised error term which is a part of the recurrent architecture ensures smooth estimation of the final pose.To demonstrate the performance of the proposed system,a complete experiment was conducted on three challenging public datasets,ICVL,MSRA,and NYU.The empirical results show the significant performance of our method which is comparable or better than the state-of-the-art approaches. 展开更多
关键词 HAND Pose Estimation Convolutional NEURAL NETWORKS Recurrent NEURAL NETWORKS HUMAN-MACHINE Interaction Predictive Coding UNSUPERVISED LEARNING
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Gated recurrent unit model for a sequence tagging problem 预览
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作者 Rekia Kadari Zhang Yu +1 位作者 Zhang Weinan Liu Ting 《高技术通讯:英文版》 CAS 2019年第1期81-87,共7页
Combinatory categorial grammer (CCG) supertagging is an important subtask that takes place before full parsing and can benefit many natural language processing (NLP) tasks like question answering and machine translati... Combinatory categorial grammer (CCG) supertagging is an important subtask that takes place before full parsing and can benefit many natural language processing (NLP) tasks like question answering and machine translation. CCG supertagging can be regarded as a sequence labeling problem that remains a challenging problem where each word is assigned to a CCG lexical category and the number of the probably associated CCG supertags to each word is large. To address this, recently recurrent neural networks (RNNs), as extremely powerful sequential models, have been proposed for CCG supertagging and achieved good performances. In this paper, a variant of recurrent networks is proposed whose design makes it much easier to train and memorize information for long range dependencies based on gated recurrent units (GRUs), which have been recently introduced on some but not all tasks. Results of the experiments revealed the effectiveness of the proposed method on the CCGBank datasets and show that the model has comparable accuracy with the previously proposed models for CCG supertagging. 展开更多
关键词 combinatory categorial grammer (CCG) CCG supertagging DEEP LEARNING GATED RECURRENT UNIT (GRU)
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Homozygous loss-of-function mutations in FSIP2 cause male infertility with asthenoteratospermia
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作者 Wangjie Liu Huan Wu +13 位作者 Li Wang Xiaoyu Yang Chunyu Liu Xiaojin He Weiyu Li Jiajia Wang Yujie Chen Hongyan Wang Yang Gao Shuyan Tang Shenmin Yang Li Jin Feng Zhang Yunxia Cao 《遗传学报:英文版》 SCIE CAS CSCD 2019年第1期53-56,共4页
Male infertility, as a major issue of human reproduction health, prevents successful natural conception. Asthenoteratospermia mainly presents one or multiple anomalies in head, neck and tail of spermatozoa, and impair... Male infertility, as a major issue of human reproduction health, prevents successful natural conception. Asthenoteratospermia mainly presents one or multiple anomalies in head, neck and tail of spermatozoa, and impairs sperm function and motility (Coutton et al., 2015). Recurrent abnormalities of the fibrous sheath lead to multiple morphological abnormaliries of the sperm flagella (MMAF), which is a quite frequent type of asthenoteratospermia in male infertility (Chemes et al., 1987;Ben Khelifa et al, 2014). 展开更多
关键词 Male INFERTILITY REPRODUCTION health Recurrent ABNORMALITIES
强化健康认知护理在复发性念珠菌阴道炎患者护理中的应用分析 预览
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作者 于小青 《中国社区医师》 2019年第18期151-152,共2页
目的:探讨强化健康认知护理在复发性念珠菌性阴道炎患者护理中的应用价值。方法:收治复发性念珠菌性阴道炎患者150例,摸球法分为A组(强化健康认知护理)与B组(常规健康教育)。比较干预效果。结果:A组疾病相关知识知晓率、依从性评分及总... 目的:探讨强化健康认知护理在复发性念珠菌性阴道炎患者护理中的应用价值。方法:收治复发性念珠菌性阴道炎患者150例,摸球法分为A组(强化健康认知护理)与B组(常规健康教育)。比较干预效果。结果:A组疾病相关知识知晓率、依从性评分及总有效率优于B组,差异有统计学意义(P<0.05)。结论:复发性念珠菌性阴道炎护理中应用强化健康认知护理效果显著。 展开更多
关键词 复发性 念珠菌性阴道炎 强化健康认知护理 护理
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