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基于T淋巴细胞亚群探析中医药治疗慢性阻塞性肺疾病的研究进展 认领

Research Progress of Traditional Chinese Medicine on Chronic Obstructive Pulmonary Disease Based on T Lymphocyte Subsets
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摘要 T淋巴细胞亚群可介导细胞免疫反应,其可通过分泌细胞因子及信号通路间的相互调节、相互制约而维持机体免疫动态平衡。慢性阻塞性肺疾病(COPD)是呼吸系统常见疾病之一,研究表明,T淋巴细胞亚群失衡在其发病机制中具有重要作用。免疫低下与中医正气不足有相通之处,近年随着中医药治疗COPD的研究深入,越来越多证据表明中医药能调节T淋巴细胞亚群,进而增强患者免疫功能。笔者基于T淋巴细胞亚群综述了中医药治疗COPD的研究进展,旨在为COPD的诊疗提供新的思路。 T lymphocyte subsets can mediate cellular immunity,it can maintain the dynamic balance of the body's immune system through the mutual regulation and restriction of cytokine secretion and signaling pathways.Chronic obstructive pulmonary disease(COPD)is one of the common diseases of the respiratory system.Studies have shown that the imbalance of T lymphocyte subsets plays an important role in its pathogenesis.Immune deficiency has something in common with traditional Chinese medicine(TCM)deficiency of vital energy.In recent years,with the deepening of studies on TCM treatment of COPD,more and more evidences show that TCM can regulate T lymphocyte subsets,thus enhancing the immune function of COPD patients.In order to provide new ideas for the diagnosis and treatment of COPD,the research progress of TCM treatment was reviewed based on T lymphocyte subsets.
作者 曹亚坤 张业清 苏克雷 何孔琴 刘兴慈 CAO Yakun;ZHANG Yeqing;SU Kelei;HE Kongqin;LIU Xingci(Nanjing University of Chinese Medicine,Nanjing 210023,China;Affiliated Hospital of Integrated Traditional Chinese and Western Medicine,Nanjing University of Chinese Medicine,Nanjing 210028,China)
出处 《实用心脑肺血管病杂志》 2021年第3期132-137,共6页 Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
基金 2019年度江苏省中医药科技发展计划项目(YB201923) 江苏省青年医学人才培养项目(QNRC2016632)。
关键词 慢性阻塞性肺疾病 T淋巴细胞亚群 中医疗法 综述 Chronic obstructive pulmonary disease T-lymphocyte subsets TCM therapy Review
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